WO2000050924A8 - Nuclear magnetic resonance analysis of multiple samples - Google Patents

Nuclear magnetic resonance analysis of multiple samples

Info

Publication number
WO2000050924A8
WO2000050924A8 PCT/US2000/004842 US0004842W WO0050924A8 WO 2000050924 A8 WO2000050924 A8 WO 2000050924A8 US 0004842 W US0004842 W US 0004842W WO 0050924 A8 WO0050924 A8 WO 0050924A8
Authority
WO
WIPO (PCT)
Prior art keywords
detection coils
magnetic resonance
nuclear magnetic
multiple samples
resonance analysis
Prior art date
Application number
PCT/US2000/004842
Other languages
French (fr)
Other versions
WO2000050924A1 (en
Inventor
Daniel Raftery
George G Fisher
Christopher J Petucci
Ernesto Macnamara
Original Assignee
Purdue Research Foundation
Daniel Raftery
George G Fisher
Christopher J Petucci
Ernesto Macnamara
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation, Daniel Raftery, George G Fisher, Christopher J Petucci, Ernesto Macnamara filed Critical Purdue Research Foundation
Priority to AU30073/00A priority Critical patent/AU3007300A/en
Publication of WO2000050924A1 publication Critical patent/WO2000050924A1/en
Priority to US09/938,996 priority patent/US6696838B2/en
Publication of WO2000050924A8 publication Critical patent/WO2000050924A8/en
Priority to US10/785,918 priority patent/US6958609B2/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
    • G01R33/34—Constructional details, e.g. resonators, specially adapted to MR
    • G01R33/34046—Volume type coils, e.g. bird-cage coils; Quadrature bird-cage coils; Circularly polarised coils
    • G01R33/34053—Solenoid coils; Toroidal coils
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/30—Sample handling arrangements, e.g. sample cells, spinning mechanisms
    • G01R33/307—Sample handling arrangements, e.g. sample cells, spinning mechanisms specially adapted for moving the sample relative to the MR system, e.g. spinning mechanisms, flow cells or means for positioning the sample inside a spectrometer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
    • G01R33/36—Electrical details, e.g. matching or coupling of the coil to the receiver
    • G01R33/3628—Tuning/matching of the transmit/receive coil
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
    • G01R33/36—Electrical details, e.g. matching or coupling of the coil to the receiver
    • G01R33/3642—Mutual coupling or decoupling of multiple coils, e.g. decoupling of a receive coil from a transmission coil, or intentional coupling of RF coils, e.g. for RF magnetic field amplification
    • G01R33/365—Decoupling of multiple RF coils wherein the multiple RF coils have the same function in MR, e.g. decoupling of a receive coil from another receive coil in a receive coil array, decoupling of a transmission coil from another transmission coil in a transmission coil array
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/30—Sample handling arrangements, e.g. sample cells, spinning mechanisms
    • G01R33/302—Miniaturized sample handling arrangements for sampling small quantities, e.g. flow-through microfluidic NMR chips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/42—Screening
    • G01R33/422—Screening of the radio frequency field

Abstract

A Nuclear Magnetic Resonance (NMR) probe device (20) is disclosed. NMR prove device (20) includes a plurality of detection coils (30, 40) each operable to detect a signal from a corresponding one of a plurality of samples (34, 44) undergoing NMR analysis. Also included is a plurality of tuning circuits (31, 41, 38, 48) each coupled to one of detection coils (30, 40) to tune the one of the detection coils (30, 40) to a corresponding resonant frequency for the NMR analysis of the corresponding one of the samples. An electromagnetic shield (22) is positioned between a first one of the detection coils (30, 40) and a second one of the detection coils (30, 40) to isolate the first one of the detection coils (30, 40) and the second one of the detection coils (30, 40) from each other.
PCT/US2000/004842 1999-02-26 2000-02-25 Nuclear magnetic resonance analysis of multiple samples WO2000050924A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU30073/00A AU3007300A (en) 1999-02-26 2000-02-25 Nuclear magnetic resonance analysis of multiple samples
US09/938,996 US6696838B2 (en) 1999-02-26 2001-08-24 Nuclear magnetic resonance analysis of multiple samples
US10/785,918 US6958609B2 (en) 1999-02-26 2004-02-24 Nuclear magnetic resonance analysis of multiple samples

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12186999P 1999-02-26 1999-02-26
US60/121,869 1999-02-26

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US09/938,996 Continuation US6696838B2 (en) 1999-02-26 2001-08-24 Nuclear magnetic resonance analysis of multiple samples

Publications (2)

Publication Number Publication Date
WO2000050924A1 WO2000050924A1 (en) 2000-08-31
WO2000050924A8 true WO2000050924A8 (en) 2001-09-27

Family

ID=22399265

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/004842 WO2000050924A1 (en) 1999-02-26 2000-02-25 Nuclear magnetic resonance analysis of multiple samples

Country Status (3)

Country Link
US (2) US6696838B2 (en)
AU (1) AU3007300A (en)
WO (1) WO2000050924A1 (en)

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Also Published As

Publication number Publication date
US6958609B2 (en) 2005-10-25
US20020130661A1 (en) 2002-09-19
US20040164738A1 (en) 2004-08-26
AU3007300A (en) 2000-09-14
US6696838B2 (en) 2004-02-24
WO2000050924A1 (en) 2000-08-31

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