WO2001034810A3 - Genes essential for microbial proliferation - Google Patents

Genes essential for microbial proliferation Download PDF

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Publication number
WO2001034810A3
WO2001034810A3 PCT/US2000/030950 US0030950W WO0134810A3 WO 2001034810 A3 WO2001034810 A3 WO 2001034810A3 US 0030950 W US0030950 W US 0030950W WO 0134810 A3 WO0134810 A3 WO 0134810A3
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WO
WIPO (PCT)
Prior art keywords
nucleic acids
screen
proliferation
proteins
coli
Prior art date
Application number
PCT/US2000/030950
Other languages
French (fr)
Other versions
WO2001034810A2 (en
Inventor
R Allyn Forsyth
Kari Ohlsen
Judith Zyskind
Original Assignee
Elitra Pharmaceuticals Inc
R Allyn Forsyth
Kari Ohlsen
Judith Zyskind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elitra Pharmaceuticals Inc, R Allyn Forsyth, Kari Ohlsen, Judith Zyskind filed Critical Elitra Pharmaceuticals Inc
Priority to AU20419/01A priority Critical patent/AU2041901A/en
Publication of WO2001034810A2 publication Critical patent/WO2001034810A2/en
Publication of WO2001034810A3 publication Critical patent/WO2001034810A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)

Abstract

The sequences of nucleic acids encoding proteins required for E. coli proliferation are disclosed. The nucleic acids can be used to express proteins or portions thereof, to obtain antibodies capable of specifically binding to the expressed proteins, and to use those expressed proteins as a screen to isolate candidate molecules for rational drug discovery programs. The nucleic acids can also be used to screen for homologous genes that are required for proliferation in microorganisms other than E. coli. The nucleic acids can also be used to design expression vectors and secretion vectors. The nucleic acids of the present invention can also be used in various assay systems to screen for proliferation required genes in other organisms as well as to screen for antimicrobial agents.
PCT/US2000/030950 1999-11-09 2000-11-09 Genes essential for microbial proliferation WO2001034810A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU20419/01A AU2041901A (en) 1999-11-09 2000-11-09 Genes essential for microbial proliferation and antisense thereto

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16441599P 1999-11-09 1999-11-09
US60/164,415 1999-11-09

Publications (2)

Publication Number Publication Date
WO2001034810A2 WO2001034810A2 (en) 2001-05-17
WO2001034810A3 true WO2001034810A3 (en) 2002-05-10

Family

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Family Applications (1)

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PCT/US2000/030950 WO2001034810A2 (en) 1999-11-09 2000-11-09 Genes essential for microbial proliferation

Country Status (3)

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US (2) US6589738B1 (en)
AU (1) AU2041901A (en)
WO (1) WO2001034810A2 (en)

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US11866728B2 (en) 2022-01-21 2024-01-09 Renagade Therapeutics Management Inc. Engineered retrons and methods of use

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Also Published As

Publication number Publication date
US6589738B1 (en) 2003-07-08
WO2001034810A2 (en) 2001-05-17
AU2041901A (en) 2001-06-06
US20030181408A1 (en) 2003-09-25

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