WO2001057190A3 - Novel nucleic acids and polypeptides - Google Patents

Novel nucleic acids and polypeptides Download PDF

Info

Publication number
WO2001057190A3
WO2001057190A3 PCT/US2001/004098 US0104098W WO0157190A3 WO 2001057190 A3 WO2001057190 A3 WO 2001057190A3 US 0104098 W US0104098 W US 0104098W WO 0157190 A3 WO0157190 A3 WO 0157190A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acids
polypeptides
novel nucleic
novel
present
Prior art date
Application number
PCT/US2001/004098
Other languages
French (fr)
Other versions
WO2001057190A2 (en
Inventor
Y Tom Tang
Chenghua Liu
Radoje T Drmanac
Vinod Asundi
Ping Zhou
Chongjun Xu
Yicheng Cao
Yunquing Ma
Qing A Zhao
Dunrui Wang
Jian-Rui Wang
Jie Zhang
Feiyan Ren
Rui-Hong Chen
Zhi Wei Wang
Aidong J Xue
Yonghong Yang
Tom Wejhrman
Ryle Goodrich
Original Assignee
Hyseq Inc
Y Tom Tang
Chenghua Liu
Radoje T Drmanac
Vinod Asundi
Ping Zhou
Chongjun Xu
Yicheng Cao
Yunquing Ma
Qing A Zhao
Dunrui Wang
Jian-Rui Wang
Jie Zhang
Feiyan Ren
Rui-Hong Chen
Zhi Wei Wang
Aidong J Xue
Yonghong Yang
Tom Wejhrman
Ryle Goodrich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/728,422 external-priority patent/US20020128187A1/en
Application filed by Hyseq Inc, Y Tom Tang, Chenghua Liu, Radoje T Drmanac, Vinod Asundi, Ping Zhou, Chongjun Xu, Yicheng Cao, Yunquing Ma, Qing A Zhao, Dunrui Wang, Jian-Rui Wang, Jie Zhang, Feiyan Ren, Rui-Hong Chen, Zhi Wei Wang, Aidong J Xue, Yonghong Yang, Tom Wejhrman, Ryle Goodrich filed Critical Hyseq Inc
Priority to EP01907128A priority Critical patent/EP1572987A4/en
Priority to AU2001234944A priority patent/AU2001234944A1/en
Priority to CA002399776A priority patent/CA2399776A1/en
Publication of WO2001057190A2 publication Critical patent/WO2001057190A2/en
Priority to US10/627,373 priority patent/US20050164202A1/en
Priority to US11/218,141 priority patent/US20070042392A1/en
Publication of WO2001057190A3 publication Critical patent/WO2001057190A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6432Coagulation factor Xa (3.4.21.6)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21006Coagulation factor Xa (3.4.21.6)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Abstract

The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
PCT/US2001/004098 2000-02-03 2001-02-05 Novel nucleic acids and polypeptides WO2001057190A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP01907128A EP1572987A4 (en) 2000-02-03 2001-02-05 Novel nucleic acids and polypeptides
AU2001234944A AU2001234944A1 (en) 2000-02-03 2001-02-05 Novel nucleic acids and polypeptides
CA002399776A CA2399776A1 (en) 2000-02-03 2001-02-05 Novel nucleic acids and polypeptides
US10/627,373 US20050164202A1 (en) 2000-02-03 2003-07-24 Materials and methods relating to therapy and diagnosis using targeting of cells that express JPL polypeptides
US11/218,141 US20070042392A1 (en) 2000-02-03 2005-08-31 Novel nucleic acids and polypeptides

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US49691400A 2000-02-03 2000-02-03
US09/496,914 2000-02-03
US56087500A 2000-04-27 2000-04-27
US09/560,875 2000-04-27
US59807500A 2000-06-20 2000-06-20
US09/598,075 2000-06-20
US62032500A 2000-07-19 2000-07-19
US09/620,325 2000-07-19
US65493600A 2000-09-01 2000-09-01
US09/654,936 2000-09-01
US66356100A 2000-09-15 2000-09-15
US09/663,561 2000-09-15
US69332500A 2000-10-20 2000-10-20
US09/693,325 2000-10-20
US09/728,422 US20020128187A1 (en) 2000-02-03 2000-11-30 Novel nucleic acids and polypeptides
US09/728,422 2000-11-30

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US65493600A Continuation-In-Part 2000-02-03 2000-09-01

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US10258899 A-371-Of-International 2001-02-05
US29324402A Continuation-In-Part 2000-02-03 2002-11-12
US11/218,141 Continuation-In-Part US20070042392A1 (en) 2000-02-03 2005-08-31 Novel nucleic acids and polypeptides

Publications (2)

Publication Number Publication Date
WO2001057190A2 WO2001057190A2 (en) 2001-08-09
WO2001057190A3 true WO2001057190A3 (en) 2006-11-16

Family

ID=27575454

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/004098 WO2001057190A2 (en) 2000-02-03 2001-02-05 Novel nucleic acids and polypeptides

Country Status (4)

Country Link
EP (1) EP1572987A4 (en)
AU (1) AU2001234944A1 (en)
CA (1) CA2399776A1 (en)
WO (1) WO2001057190A2 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8835387B2 (en) 2012-02-16 2014-09-16 Atyr Pharma, Inc. Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases
US8958881B2 (en) 2005-08-19 2015-02-17 Brainsgate Ltd. Neuroprotective electrical stimulation
US9127268B2 (en) 2009-12-11 2015-09-08 Atyr Pharma, Inc. Aminoacyl tRNA synthetases for modulating inflammation
US9233245B2 (en) 2004-02-20 2016-01-12 Brainsgate Ltd. SPG stimulation
US9422539B2 (en) 2010-07-12 2016-08-23 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-tRNA synthetases
US9587235B2 (en) 2013-03-15 2017-03-07 Atyr Pharma, Inc. Histidyl-tRNA synthetase-Fc conjugates

Families Citing this family (154)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000073454A1 (en) * 1999-06-02 2000-12-07 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO2001034627A1 (en) * 1999-11-12 2001-05-17 Human Genome Sciences, Inc. 28 human secreted proteins
US20020137890A1 (en) 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7057017B2 (en) 1997-04-16 2006-06-06 Millennium Pharmaceuticals, Inc. Human dickkopf-related protein and nucleic acid molecules and uses therefor
US20030083461A1 (en) 1997-06-16 2003-05-01 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7446181B2 (en) 1998-01-15 2008-11-04 Millennium Pharmaceuticals, Inc. Antibodies that bind human Dickkopf-1 proteins
US20030149531A1 (en) 2000-12-06 2003-08-07 Hubert Rene S. Serpentine transmembrane antigens expressed in human cancers and uses thereof
DK1086223T3 (en) 1998-06-01 2009-11-30 Agensys Inc Novel serpentine transmembrane antigens expressed in human cancers and their applications
US6833438B1 (en) 1999-06-01 2004-12-21 Agensys, Inc. Serpentine transmembrane antigens expressed in human cancers and uses thereof
US7264801B2 (en) 1998-08-11 2007-09-04 Genentech, Inc. EG-VEGF nucleic acids and polypeptides and method of use
US20020172678A1 (en) 2000-06-23 2002-11-21 Napoleone Ferrara EG-VEGF nucleic acids and polypeptides and methods of use
US20030003507A1 (en) 1999-06-02 2003-01-02 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US6344541B1 (en) 1998-09-25 2002-02-05 Amgen Inc. DKR polypeptides
JP2002534112A (en) 1999-01-15 2002-10-15 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド Bone marrow specific protein
US7034132B2 (en) 2001-06-04 2006-04-25 Anderson David W Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US20030204052A1 (en) * 2000-10-04 2003-10-30 Herrmann John L. Novel proteins and nucleic acids encoding same and antibodies directed against these proteins
KR20020033763A (en) * 1999-08-19 2002-05-07 구로카와 기요시 Meg-1 protein
US20020042062A1 (en) 1999-09-24 2002-04-11 Mark Stearns Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
US7790861B2 (en) * 1999-09-24 2010-09-07 Philadelphia Health And Education Corporation Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
AU2288601A (en) 1999-12-23 2001-07-03 Millennium Pharmaceuticals, Inc. P2Y12 receptor
WO2001059079A1 (en) 2000-02-11 2001-08-16 Glycozym Aps UDP-GALACTOSE: β-D-GALACTOSE-R 4-α-D-GALACTOSYLTRANSFERASE, α4GAL-T1
JP4342069B2 (en) * 2000-02-14 2009-10-14 生化学工業株式会社 α1,4-Galactosyltransferase and DNA encoding the same
AU6802801A (en) * 2000-03-01 2001-09-24 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU2001242750A1 (en) * 2000-03-24 2001-10-03 Takeda Chemical Industries Ltd. Novel protein, process for producing the same and use thereof
AU5904101A (en) * 2000-04-05 2001-10-23 Hyseq Inc Methods and materials relating to novel stem cell growth factor-like polypeptides and polynucleotides
WO2001079466A2 (en) * 2000-04-18 2001-10-25 Bayer Aktiengesellschaft Regulation of human epithin-like serine protease
EP1280917A2 (en) * 2000-04-26 2003-02-05 Millennium Pharmaceuticals, Inc. 21657, a human short-chain dehydrogenase and uses thereof
US7510845B2 (en) 2000-05-04 2009-03-31 California Institute Of Technology Assay employing G protein-coupled receptor expressed in dorsal root ganglia
US20030092035A1 (en) 2000-05-04 2003-05-15 Anderson David J. Pain signaling molecules
WO2001085935A2 (en) * 2000-05-09 2001-11-15 Bayer Aktiengesellschaft Endothelial differentiation gene 6-like g protein coupled receptor
EP1311688A2 (en) * 2000-05-26 2003-05-21 Millennium Pharmaceuticals, Inc. 50250, a human lipase and uses thereof
WO2001096375A2 (en) * 2000-06-16 2001-12-20 Millennium Pharmaceuticals, Inc. 33358, a novel human ankyrin family member and uses thereof
CA2414015A1 (en) * 2000-06-21 2001-12-27 Incyte Genomics, Inc. Human receptors
EP1325114A2 (en) * 2000-06-26 2003-07-09 Millennium Pharmaceuticals, Inc. A human beta-ketoacyl synthase (46619) and uses thereof
WO2002002599A2 (en) * 2000-06-30 2002-01-10 Ingenium Pharmaceuticals Ag HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR17, AND USES THEROF
AU2001281974A1 (en) * 2000-07-13 2002-01-30 Novartis Ag Disease-associated gene
WO2002008392A2 (en) * 2000-07-25 2002-01-31 Bayer Aktiengesellschaft Regulation of human matriptase-like serine protease
WO2002010217A2 (en) 2000-08-02 2002-02-07 The Johns Hopkins University Endothelial cell expression patterns
WO2003024276A1 (en) * 2000-08-02 2003-03-27 Millennium Pharmaceuticals,Inc. A human gtp-releasing factor family member (15368) and uses therefor
CA2417368A1 (en) * 2000-08-04 2002-02-14 Xin Lu Suppressor gene
EP1688496A3 (en) * 2000-08-14 2006-08-16 Actimis Pharmaceuticals, Inc., Regulation of human P2Y1-like G protein-coupled receptor
ATE315089T1 (en) * 2000-08-14 2006-02-15 REGULATION OF THE HUMAN P2Y1-LIKE G-PROTEIN COUPLED RECEPTOR
AU2001284902A1 (en) * 2000-08-15 2002-02-25 Zymogenetics Inc. Human adenosine deaminase
US6706513B2 (en) 2000-08-21 2004-03-16 Bristol-Myers Squibb Company Adenosine deaminase homolog
US20030166300A1 (en) * 2000-08-30 2003-09-04 Tang Y. Tom Growth-related inflammatory and immune response protein
AU2001285908A1 (en) * 2000-08-30 2002-03-13 Bayer Aktiengesellschaft Regulation of human aminotransferase-like enzyme
EP1317527A2 (en) * 2000-09-15 2003-06-11 Institut National De La Sante Et De La Recherche Medicale (Inserm) Cellular genes involved in oncogenesis, products of said genes and their diagnostic and therapeutic uses
US7754435B2 (en) * 2000-09-21 2010-07-13 Philadelphia Health And Education Corporation Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
AU2002220613A1 (en) * 2000-10-11 2002-04-22 Bayer Aktiengesellschaft Regulation of human cyclophilin-type peptidyl-prolyl cis-trans isomerase
US6984502B2 (en) 2000-10-19 2006-01-10 Millennium Pharmaceuticals, Inc. Methods and compositions of human 69087 nucleic acids and uses thereof
WO2002036625A2 (en) 2000-11-03 2002-05-10 The Regents Of The University Of California Prokineticin polypeptides, related compositions and methods
WO2002077233A2 (en) * 2000-11-08 2002-10-03 Millennium Pharmaceuticals, Inc. 38650, 28472, 5495, 65507, 81588 and 14354 METHODS AND COMPOSITIONS OF HUMAN PROTEINS AND USES THEREOF
ATE477332T1 (en) * 2000-11-09 2010-08-15 Univ Virginia HUMAN TESTIS-SPECIFIC SERINE/THREONINE KINASE
WO2002038743A2 (en) * 2000-11-09 2002-05-16 Glaxo Group Limited Deaminase catalyzing the removal of the cyclopropyl moiety from abacavir-mp
US7312086B2 (en) 2000-12-07 2007-12-25 Bristol-Myers Squibb Company Methods of diagnosing colon adenocarcinoma using the human g-protein coupled receptor hgprbmy23
AU2002232822A1 (en) * 2000-12-21 2002-07-01 Incyte Genomics, Inc. Nucleic acid-associated proteins
US7892730B2 (en) * 2000-12-22 2011-02-22 Sagres Discovery, Inc. Compositions and methods for cancer
US20030148920A1 (en) * 2000-12-27 2003-08-07 Steven Rosen Sulfatases and methods of use thereof
WO2002053719A2 (en) * 2001-01-04 2002-07-11 Incyte Genomics, Inc. Cytoskeleton-associated proteins
WO2002064792A2 (en) * 2001-01-05 2002-08-22 Incyte Genomics, Inc. Molecules for disease detection and treatment
US6319679B1 (en) * 2001-01-26 2001-11-20 Board Of Regents, The University Of Texas System PAS kinase
US20020115136A1 (en) * 2001-02-07 2002-08-22 Gennady Merkulov Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002064777A2 (en) * 2001-02-14 2002-08-22 Axaron Bioscience Ag Proteins 7b6 and 11b4 and dna sequences encoding the same
WO2002074913A2 (en) * 2001-03-16 2002-09-26 Incyte Genomics, Inc. Nucleic acid-associated proteins
US20030044813A1 (en) * 2001-03-30 2003-03-06 Old Lloyd J. Cancer-testis antigens
US20020146795A1 (en) * 2001-04-02 2002-10-10 Shiaoping Zhu Isolated human Ras-like proteins, nucleic acid molecules encoding these human Ras-like proteins, and uses thereof
WO2002083921A2 (en) 2001-04-10 2002-10-24 Agensys, Inc. Nuleic acids and corresponding proteins useful in the detection and treatment of various cancers
US7927597B2 (en) * 2001-04-10 2011-04-19 Agensys, Inc. Methods to inhibit cell growth
US6962811B2 (en) 2001-05-09 2005-11-08 Millennium Pharmaceuticals, Inc. 14715, a human fringe family member nucleic acids and uses therefor
WO2002097088A1 (en) * 2001-05-29 2002-12-05 Human Cell Systems, Inc. Testicular carnitine transporter and its gene
DE60237917D1 (en) 2001-06-05 2010-11-18 Exelixis Inc GFATS AS MODULATORS OF THE P53 PATH AND METHOD OF USE
CA2633171C (en) * 2001-06-20 2012-11-20 Genentech, Inc. Antibodies against tumor-associated antigenic target (tat) polypeptides
WO2003000874A2 (en) * 2001-06-25 2003-01-03 Bayer Aktiengesellschaft Regulation of human serine/threonine protein kinase nek3
US7494646B2 (en) 2001-09-06 2009-02-24 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
EP2287186B1 (en) 2001-09-06 2014-12-31 Agensys, Inc. Nucleic acid and corresponding protein entitled STEAP-1 useful in treatment and detection of cancer
ES2276964T3 (en) * 2001-09-24 2007-07-01 Grunenthal Gmbh SCREENING PROCEDURE USED BY BNPI FOR DIFFERENT INDICATIONS.
US7265214B2 (en) 2001-10-19 2007-09-04 Rigel Pharmaceuticals, Inc. Germinal center kinase proteins, compositions and methods of use
AU2002349924A1 (en) * 2001-10-29 2003-05-12 Millennium Pharmaceuticals, Inc. 32235, a human aminotransferase family member and uses therefor
WO2003037253A2 (en) 2001-10-31 2003-05-08 Millennium Pharmaceuticals, Inc. Methods for the treatment and diagnosis of tumorigenic and angiogenic disorders using 32616
EP1440169A4 (en) * 2001-10-31 2005-09-21 Millennium Pharm Inc Methods and compositions for the treatment and diagnosis of pain disorders using 57749
DE60220621T2 (en) 2001-11-09 2008-03-06 Proteologics, Inc. Posh nucleic acid, polypeptides and related methods
AU2002360460A1 (en) * 2001-12-03 2003-06-17 Nuvelo, Inc. Methods and materials relating to novel polypeptides and polynucleotides
AU2002356624A1 (en) * 2001-12-04 2003-06-17 Develogen Aktiengesellschaft Fur Entwicklungsbiologische Forschung Ptp10d, tec and edtp involved in triglycerid-metabolism
WO2003054153A2 (en) * 2001-12-12 2003-07-03 University Of Cincinnati Apyrase polypeptides and nucleic acids encoding same
EP1458754B1 (en) * 2001-12-18 2009-12-09 Endocube SAS Novel death associated proteins of the thap family and related par4 pathways involved in apoptosis control
US7858297B2 (en) 2001-12-18 2010-12-28 Centre National De La Recherche Scientifique Cnrs Chemokine-binding protein and methods of use
AU2003244347A1 (en) * 2002-02-04 2003-09-02 Takeda Chemical Industries, Ltd. Angiogenesis inhibitors
GB0205112D0 (en) * 2002-03-05 2002-04-17 Pantherix Ltd Enzyme
JP4176022B2 (en) 2002-03-11 2008-11-05 独立行政法人科学技術振興機構 Practical chiral zirconium catalyst
DE10212397A1 (en) * 2002-03-20 2003-10-16 Universitaetsklinikum Freiburg Repressor of skeletal muscle differentiation, nucleic acid coding for it and its use in diagnostics and therapy
AU2003221052A1 (en) * 2002-03-29 2003-10-27 Celestar Lexico-Sciences, Inc. c-Jun PHOSPHORYLATION INHIBITORS
US20050202431A1 (en) * 2002-04-01 2005-09-15 National Institute Of Advanced Industrial Science Application of kiaa0172 gene to treatment and diagnosis of diseases and drug discovery
US7538088B2 (en) 2002-04-26 2009-05-26 California Institute Of Technology Method for inhibiting angiogenesis by administration of the extracellular domain of D1-1 polypeptide
US7622443B2 (en) 2002-04-26 2009-11-24 California Institute Of Technology Method for inhibiting pro-angiogenic activities of endothelial cells selectively at a site of neoangiogenesis in a mammal by administration of the extracellular domain of D1-1 polypeptides
DE10222845A1 (en) * 2002-05-23 2003-12-04 Dresden Arzneimittel Cloning, expression and characterization of the overall sequence of phosphodiesterase 8B
DE60334400D1 (en) * 2002-06-28 2010-11-11 Imclone Llc NEW POLYNUCLEOTIDE AND POLYPEPTIDE SEQUENCES AND THEIR USES
CA2493007A1 (en) * 2002-07-19 2004-01-29 Cellzome Ag Protein complexes of the tip60 transcriptional activator protein
US7135556B2 (en) 2002-07-19 2006-11-14 Schering Corporation NPC1L1 (NPC3) and methods of use thereof
JP2004290170A (en) * 2002-08-02 2004-10-21 Takeda Chem Ind Ltd Use of gene associated with disease
TW200413725A (en) * 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
US7056685B1 (en) 2002-11-05 2006-06-06 Amgen Inc. Receptor ligands and methods of modulating receptors
US20080213166A1 (en) * 2002-11-20 2008-09-04 Biogen Idec Inc. Novel Gene Targets and Ligands that Bind Thereto for Treatment and Diagnosis of Colon Carcinomas
US20040224408A1 (en) * 2002-12-10 2004-11-11 Jean-Philippe Girard THAP proteins as nuclear receptors for chemokines and roles in transcriptional regulation, cell proliferation and cell differentiation
JP4140951B2 (en) * 2002-12-18 2008-08-27 独立行政法人科学技術振興機構 Transcriptional regulator ZHX3
EP2141235B1 (en) 2002-12-29 2014-06-11 Toudai Tlo, Ltd. Adiponectin receptor and gene coding for the same
AU2004206250B8 (en) * 2003-01-21 2009-09-17 Bristol-Myers Squibb Company Polynucleotide encoding a novel acyl coenzyme a, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof
KR20090096561A (en) * 2003-02-03 2009-09-10 도쿠리쓰교세이호징 가가쿠 기주쓰 신코 기코 REGENERATION AND NEOGENESIS OF RETINAL VISUAL CELL WITH Otx2 GENE
AU2004293369A1 (en) * 2003-03-03 2005-06-09 Genentech, Inc. Compositions and methods for the treatment of systemic lupus erythematosis
CA2522994C (en) * 2003-04-30 2012-09-25 Agensys, Inc. Nucleic acids and corresponding proteins entitled 109p1d4 useful in treatment and detection of cancer
WO2004104218A1 (en) * 2003-05-23 2004-12-02 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with x-prolyl aminopeptidase (aminopeptidase p) 1 (xpnpep1)
WO2005023855A2 (en) * 2003-09-10 2005-03-17 Friedrich-Alexander-Uni- Versitatet Erlangen- Nuernberg K203 gene and protein
JP4634302B2 (en) * 2003-09-30 2011-02-16 第一三共株式会社 Tetrahydrofolate synthase gene
WO2005059504A2 (en) * 2003-12-12 2005-06-30 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled receptor gpr34 (gpr34)
WO2005069900A2 (en) 2004-01-16 2005-08-04 Merck & Co., Inc. Npc1l1 (npc3) and methods of identifying ligands thereof
CA2555675A1 (en) * 2004-02-10 2005-08-25 Trustees Of Dartmouth College Nicotinamide riboside kinase compositions and methods for using the same
US8010189B2 (en) 2004-02-20 2011-08-30 Brainsgate Ltd. SPG stimulation for treating complications of subarachnoid hemorrhage
EP1786833A4 (en) * 2004-03-19 2009-02-25 Univ Yale Detection, isolation and uses of renalase (monoamine oxidase c)
KR101204286B1 (en) * 2004-03-30 2012-11-26 엔에스진 에이/에스 Therapeutic use of a growth factor, NsG33
US20050222040A1 (en) * 2004-04-05 2005-10-06 Blm Group, Inc. Vertebrate peptide modulators of lipid metabolism
CN101258166B (en) 2004-04-22 2013-01-30 阿根西斯公司 Antibody combining with STEAP-1 protein and deriving molecule thereof
WO2006015373A2 (en) 2004-08-04 2006-02-09 Amgen Inc Antibodies to dkk-1
WO2006069592A2 (en) * 2004-12-31 2006-07-06 Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg Method for diagnosing an/or predicting preeclampsia and/or related disorders
FI20050011A (en) * 2005-01-05 2006-07-06 Jurilab Ltd Oy Procedure and test package to detect the risk of type 2 diabetes mellitus
WO2006074914A2 (en) * 2005-01-13 2006-07-20 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research Human rna helicase and therapeutic uses thereof
US7521195B1 (en) 2005-07-21 2009-04-21 Celera Corporation Lung disease targets and uses thereof
EP1951291A4 (en) 2005-11-21 2012-04-04 Univ Yale Methods of regulating renalase (monoamine oxidase c)
US9206242B2 (en) * 2005-11-22 2015-12-08 National University Corporation Nagoya University Application of actin-binding protein to disease associated with cell motility
US7910698B2 (en) 2006-02-24 2011-03-22 Schering Corporation NPC1L1 orthologues
KR101541550B1 (en) 2006-10-27 2015-08-04 제넨테크, 인크. Antibodies and immunoconjugates and uses therefor
WO2008136541A1 (en) * 2007-05-02 2008-11-13 Snu R&Db Foundation Angiogenesis inhibitor comprising meteorin as an active ingredient
US8158758B2 (en) 2007-07-02 2012-04-17 Oncomed Pharmaceuticals, Inc. Compositions and methods for treating and diagnosing cancer
US20100209436A1 (en) * 2007-07-03 2010-08-19 Andreas Reichert Method for treating diseases related to mitochondrial dysfunction
US20100204128A1 (en) * 2007-07-24 2010-08-12 Sanare Investment As Novel peptides
CN101910196A (en) 2007-12-28 2010-12-08 诺沃-诺迪斯克有限公司 DDR1-mediated cell purification of pancreatic endocrine cells through their progenitors
AU2009273600B2 (en) 2008-07-24 2013-04-18 Hoba Therapeutics Aps Therapeutic use of a growth factor, METRNL
EP3255146B1 (en) 2009-03-16 2019-05-15 Pangu Biopharma Limited Compositions and methods comprising histidyl-trna synthetase splice variants having non-canonical biological activities
AR075989A1 (en) 2009-04-10 2011-05-11 Lilly Co Eli ANTIBODY DKK -1 (DICKKOPF-1) HUMAN DESIGNED BY ENGINEERING
US8815779B2 (en) 2009-09-16 2014-08-26 SwitchGear Genomics, Inc. Transcription biomarkers of biological responses and methods
CN102741294A (en) 2009-11-30 2012-10-17 霍夫曼-拉罗奇有限公司 Antibodies for treating and diagnosing tumors expressing SLC34A2 (TAT211 = SEQID 2)
JP6008843B2 (en) 2010-05-04 2016-10-19 エータイアー ファーマ, インコーポレイテッド Innovative discovery of therapeutic, diagnostic and antibody compositions related to protein fragments of glutamyl-prolyl tRNA synthetase
CN108079279B (en) 2010-10-01 2022-04-12 霍巴治疗公司 Use of nickel-line protein for treating allodynia, hyperalgesia, spontaneous pain and phantom pain
CN106167526A (en) 2011-07-15 2016-11-30 昂考梅德药品有限公司 RSPO bonding agent and its application
US9474786B2 (en) 2011-09-05 2016-10-25 Nsgene A/S Treatment of allodynia
IN2015KN00350A (en) 2012-07-13 2015-07-10 Oncomed Pharm Inc
EP2742935A1 (en) * 2012-12-14 2014-06-18 Tissue Med Biosciences Forschungs- und Entwicklungsgesellschaft mbH SERF2 for the treatment of atrophy and for increasing cell growth
US9675796B2 (en) 2013-11-10 2017-06-13 Brainsgate Ltd. Implant and delivery system for neural stimulator
MA40574A (en) 2014-09-16 2016-03-24 Oncomed Pharm Inc Treatment of fibrotic diseases
US10271907B2 (en) 2015-05-13 2019-04-30 Brainsgate Ltd. Implant and delivery system for neural stimulator
CN110049769A (en) 2016-12-04 2019-07-23 阿拉维·霍拉萨尼·默哈达姆·马塞尔·维克托 Treatment and mitochondria stress relevant disease method
US10905766B2 (en) * 2017-03-23 2021-02-02 Oregon State University Therapeutic compositions and methods for treatment of muscle wasting diseases
CA3055132A1 (en) 2017-04-03 2018-10-11 F. Hoffmann-La Roche Ag Antibodies binding to steap-1
US11767520B2 (en) 2017-04-20 2023-09-26 Atyr Pharma, Inc. Compositions and methods for treating lung inflammation
CN110910960B (en) * 2019-11-30 2022-07-08 浙江天科高新技术发展有限公司 Acinetobacter baumannii molecular serotype rapid analysis method
MX2023004579A (en) * 2020-12-08 2023-05-04 Imagine Pharma Llc Compositions and methods for treating wounds.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7172198A (en) * 1997-04-29 1998-11-24 Incyte Pharmaceuticals, Inc. Human c-type lectin
GB9711148D0 (en) * 1997-05-31 1997-07-23 Peptide Therapeutics Ltd Human MAFA

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] accession no. NCBI Database accession no. (AI765329) *
See also references of EP1572987A4 *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9233245B2 (en) 2004-02-20 2016-01-12 Brainsgate Ltd. SPG stimulation
US8958881B2 (en) 2005-08-19 2015-02-17 Brainsgate Ltd. Neuroprotective electrical stimulation
US9127268B2 (en) 2009-12-11 2015-09-08 Atyr Pharma, Inc. Aminoacyl tRNA synthetases for modulating inflammation
US9328340B2 (en) 2009-12-11 2016-05-03 Atyr Pharma, Inc. Amino acyl tRNA synthetases for modulating inflammation
US9540628B2 (en) 2009-12-11 2017-01-10 Atyr Pharma, Inc. Aminoacyl tRNA synthetases for modulating inflammation
US9422539B2 (en) 2010-07-12 2016-08-23 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-tRNA synthetases
US8835387B2 (en) 2012-02-16 2014-09-16 Atyr Pharma, Inc. Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases
US9273302B2 (en) 2012-02-16 2016-03-01 Atyr Pharma, Inc. Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases
US9587235B2 (en) 2013-03-15 2017-03-07 Atyr Pharma, Inc. Histidyl-tRNA synthetase-Fc conjugates

Also Published As

Publication number Publication date
AU2001234944A1 (en) 2001-08-14
EP1572987A2 (en) 2005-09-14
EP1572987A4 (en) 2005-11-30
WO2001057190A2 (en) 2001-08-09
AU2001234944A8 (en) 2006-12-21
CA2399776A1 (en) 2001-08-09

Similar Documents

Publication Publication Date Title
WO2001075067A3 (en) Novel nucleic acids and polypeptides
WO2001057188A3 (en) Novel nucleic acids and polypeptides
WO2001057190A3 (en) Novel nucleic acids and polypeptides
WO2002022660A3 (en) Novel nucleic acids and polypeptides
WO2001066689A3 (en) Novel nucleic acids and polypeptides
WO2002031111A3 (en) Novel nucleic acids and polypeptides
WO2001088088A3 (en) Novel nucleic acids and polypeptides
WO2002059260A3 (en) Nucleic acids and polypeptides
WO2003054152A3 (en) Novel nucleic acids and polypeptides
WO2003025148A3 (en) Novel nucleic acids and polypeptides
WO2002070539A3 (en) Novel nucleic acids and polypeptides
WO2003023013A3 (en) Novel nucleic acids and polypeptides
WO2002081731A3 (en) Novel nucleic acids and polypeptides
WO2001053312A8 (en) Novel nucleic acids and polypeptides
WO2001053455A3 (en) Novel nucleic acids and polypeptides
WO2004009834A3 (en) Novel nucleic acids and secreted polypeptides
WO2003029271A3 (en) Novel nucleic acids and polypeptides
WO2004080148A3 (en) Novel nucleic acids and polypeptides
WO2002018424A3 (en) Nucleic acids and polypeptides
WO2004087874A3 (en) Novel nucleic acids and polypeptides
WO2001079449A3 (en) Novel nucleic acids and polypeptides
WO2001002571A3 (en) An interleukin-1 receptor antagonist and uses thereof
WO2003080795A8 (en) Novel nucleic acids and secreted polypeptides
WO2001075068A3 (en) Secreted proteins and polynucleotides encoding them
WO2002044340A3 (en) Novel nucleic acids and polypeptides

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US US US US US US US US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWE Wipo information: entry into national phase

Ref document number: 2399776

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2001907128

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP

WWE Wipo information: entry into national phase

Ref document number: 11218141

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 2001907128

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 11218141

Country of ref document: US