WO2001079469A3 - Cloning of corynebacteriaceae histidine ammonia lyase and therapeutic uses - Google Patents
Cloning of corynebacteriaceae histidine ammonia lyase and therapeutic uses Download PDFInfo
- Publication number
- WO2001079469A3 WO2001079469A3 PCT/US2001/012053 US0112053W WO0179469A3 WO 2001079469 A3 WO2001079469 A3 WO 2001079469A3 US 0112053 W US0112053 W US 0112053W WO 0179469 A3 WO0179469 A3 WO 0179469A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- corynebacteriaceae
- histidine
- histidine ammonia
- ammonia lyase
- cloning
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y403/00—Carbon-nitrogen lyases (4.3)
- C12Y403/01—Ammonia-lyases (4.3.1)
- C12Y403/01003—Histidine ammonia-lyase (4.3.1.3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2001257032A AU2001257032A1 (en) | 2000-04-14 | 2001-04-13 | Cloning, overexpression and therapeutic uses of bioactive histidine ammonia lyase |
CA002406390A CA2406390A1 (en) | 2000-04-14 | 2001-04-13 | Cloning, overexpression and therapeutic uses of bioactive histidine ammonia lyase |
JP2001577453A JP2003530850A (en) | 2000-04-14 | 2001-04-13 | Cloning, overexpression and therapeutic use of bioactive histidine ammonia lyase |
EP01930503A EP1280924A2 (en) | 2000-04-14 | 2001-04-13 | Cloning of corynebacteriaceae histidine ammonia lyase and therapeutic uses |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19777000P | 2000-04-14 | 2000-04-14 | |
US60/197,770 | 2000-04-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001079469A2 WO2001079469A2 (en) | 2001-10-25 |
WO2001079469A3 true WO2001079469A3 (en) | 2002-05-10 |
Family
ID=22730684
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/012053 WO2001079469A2 (en) | 2000-04-14 | 2001-04-13 | Cloning of corynebacteriaceae histidine ammonia lyase and therapeutic uses |
Country Status (6)
Country | Link |
---|---|
US (2) | US6939541B2 (en) |
EP (1) | EP1280924A2 (en) |
JP (1) | JP2003530850A (en) |
AU (1) | AU2001257032A1 (en) |
CA (1) | CA2406390A1 (en) |
WO (1) | WO2001079469A2 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7181608B2 (en) * | 2000-02-03 | 2007-02-20 | Realtime Data Llc | Systems and methods for accelerated loading of operating systems and application programs |
JP2003289869A (en) * | 2002-04-02 | 2003-10-14 | Tosoh Corp | Oligonucleotide for assaying mycobacterium avium as atypical acid-fast bacterium, and method for detecting the same |
FI20031793A0 (en) * | 2003-12-09 | 2003-12-09 | Lasse Leino | New anti-proliferative pharmaceutical composition |
US7553653B2 (en) * | 2004-09-17 | 2009-06-30 | Biomarin Pharmaceutical Inc. | Variants and chemically-modified variants of phenylalanine ammonia-lyase |
EP2886658A1 (en) | 2005-03-10 | 2015-06-24 | BASF Enzymes LLC | Lyase enzymes, nucleic acids encoding them and methods for making and using them |
US20110027346A1 (en) * | 2006-06-02 | 2011-02-03 | Verenium Corporation | Lyase Enzymes, Nucleic Acids Encoding Them and Methods for Making and Using Them |
US7531341B1 (en) | 2006-06-12 | 2009-05-12 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof |
US7534595B2 (en) * | 2006-06-12 | 2009-05-19 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof |
US7560263B2 (en) * | 2007-08-17 | 2009-07-14 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof |
WO2010014225A2 (en) | 2008-07-30 | 2010-02-04 | Biomarin Pharmaceutical Inc. | Assays for detection of phenylalanine ammonia-lyase and antibodies to phenylalanine ammonia-lyase |
ES2582459T3 (en) | 2010-02-04 | 2016-09-13 | Biomarin Pharmaceutical Inc. | Compositions of phenylalanine ammonia-lyase variants of prokaryotes and methods of using their compositions |
WO2017150304A1 (en) * | 2016-02-29 | 2017-09-08 | 長瀬産業株式会社 | Fermentation product of ergothioneine |
CN109673548B (en) * | 2018-12-29 | 2021-08-06 | 汕头大学 | Application of urocanic acid in preparation of anti-white spot syndrome virus preparation |
WO2023283558A1 (en) * | 2021-07-08 | 2023-01-12 | Regeneron Pharmaceuticals, Inc. | Methods of treating skin cancer with histidine ammonia-lyase (hal) agonists |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4955857A (en) * | 1988-07-18 | 1990-09-11 | Shettigar Udipi R | Multi-enzyme bioreactor therapy for cancer |
ES2063574T3 (en) * | 1990-12-17 | 1995-01-01 | Univ Manitoba | IMPROVED TREATMENT METHOD FOR CANCER. |
US5824784A (en) * | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
-
2001
- 2001-04-13 EP EP01930503A patent/EP1280924A2/en not_active Withdrawn
- 2001-04-13 WO PCT/US2001/012053 patent/WO2001079469A2/en active Application Filing
- 2001-04-13 JP JP2001577453A patent/JP2003530850A/en active Pending
- 2001-04-13 US US09/833,745 patent/US6939541B2/en not_active Expired - Fee Related
- 2001-04-13 AU AU2001257032A patent/AU2001257032A1/en not_active Abandoned
- 2001-04-13 CA CA002406390A patent/CA2406390A1/en not_active Abandoned
-
2005
- 2005-05-24 US US11/135,667 patent/US20060034817A1/en not_active Abandoned
Non-Patent Citations (6)
Title |
---|
BRAND L M ET AL: "HISTIDINE AMMONIA LYASE EC-4.3.1.3 FROM RAT LIVER PURIFICATION PROPERTIES AND INHIBITION BY SUBSTRATE ANALOGS", BIOCHEMISTRY, vol. 15, no. 9, 1976, pages 1814 - 1821, XP002188387, ISSN: 0006-2960 * |
DE FABO E C ET AL: "Altered skin cytokine environment after UVB irradiation in UCA-deficient histidinemic C57BL/6-HalEdi mice.", PHOTOCHEMISTRY AND PHOTOBIOLOGY, vol. 69, no. SPEC. ISSUE., June 1999 (1999-06-01), Twenty Seventh Annual Meeting of the American Society for Photobiology;Washington, D.C., USA; July 10-15,1999, pages 18S - 19S, XP001053095, ISSN: 0031-8655 * |
ROBERTS J ET AL: "BIOLOGIC AND ANTI NEOPLASTIC EFFECTS OF ENZYME MEDIATED IN-VIVO DEPLETION OF L GLUTAMINE L TRYPTOPHAN AND L HISTIDINE", CANCER TREATMENT REPORTS, vol. 63, no. 6, 1979, pages 1045 - 1054, XP010309040, ISSN: 0361-5960 * |
See also references of EP1280924A2 * |
WU P-C ET AL: "PURIFICATION OF HISTIDASE FROM STREPTOMYCES-GRISEUS AND NUCLEOTIDE SEQUENCE OF THE HUTH STRUCTURAL GENE", JOURNAL OF BACTERIOLOGY, vol. 174, no. 5, 1992, pages 1647 - 1655, XP001053073, ISSN: 0021-9193 * |
ZAHARKO D ET AL: "L HISTIDINOL PRECLINICAL THERAPEUTIC STUDIES IN COMBINATION WITH ANTITUMOR AGENTS AND PHARMACOKINETIC STUDIES IN MICE", CANCER RESEARCH, vol. 52, no. 13, 1992, pages 3604 - 3609, XP002188388, ISSN: 0008-5472 * |
Also Published As
Publication number | Publication date |
---|---|
AU2001257032A1 (en) | 2001-10-30 |
EP1280924A2 (en) | 2003-02-05 |
US6939541B2 (en) | 2005-09-06 |
US20060034817A1 (en) | 2006-02-16 |
JP2003530850A (en) | 2003-10-21 |
WO2001079469A2 (en) | 2001-10-25 |
US20020052038A1 (en) | 2002-05-02 |
CA2406390A1 (en) | 2001-10-25 |
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