WO2002008740A3 - Apparatus and method for probing light absorbing agents in biological tissues - Google Patents

Apparatus and method for probing light absorbing agents in biological tissues Download PDF

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Publication number
WO2002008740A3
WO2002008740A3 PCT/IL2001/000674 IL0100674W WO0208740A3 WO 2002008740 A3 WO2002008740 A3 WO 2002008740A3 IL 0100674 W IL0100674 W IL 0100674W WO 0208740 A3 WO0208740 A3 WO 0208740A3
Authority
WO
WIPO (PCT)
Prior art keywords
radiation
ultrasound
interest
region
electromagnetic radiation
Prior art date
Application number
PCT/IL2001/000674
Other languages
French (fr)
Other versions
WO2002008740A2 (en
Inventor
Bruno Gad Sfez
Aner Lev
Zvi Kotler
Original Assignee
Israel Atomic Energy Comm
Bruno Gad Sfez
Aner Lev
Zvi Kotler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Israel Atomic Energy Comm, Bruno Gad Sfez, Aner Lev, Zvi Kotler filed Critical Israel Atomic Energy Comm
Priority to US10/333,684 priority Critical patent/US6815694B2/en
Priority to DE60106270T priority patent/DE60106270T2/en
Priority to AU2001278665A priority patent/AU2001278665A1/en
Priority to AT01956750T priority patent/ATE278947T1/en
Priority to EP01956750A priority patent/EP1303756B1/en
Publication of WO2002008740A2 publication Critical patent/WO2002008740A2/en
Publication of WO2002008740A3 publication Critical patent/WO2002008740A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0097—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying acoustic waves and detecting light, i.e. acoustooptic measurements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4416—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to combined acquisition of different diagnostic modalities, e.g. combination of ultrasound and X-ray acquisitions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717—Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/0035—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography

Abstract

A method and apparatus are presented for detecting an effect of interactions of electromagnetic radiation with ultrasound radiation at different locations within a region of interest in a scattering medium to thereby enable imaging of said medium. A plurality of sequences of pulses of ultrasound radiation is transmitted towards a plurality of locations, respectively, in said region of interest within an X-Y plane perpendicular to axes of propagation of the ultrasound pulses. Said region of interest is illuminated with incident electromagnetic radiation of at least one wavelength. The phases of the ultrasound radiation or the phases of the electromagnetic radiation components are appropriately controlled in order to be enable identification of the interactions between the electromagnetic and ultrasound radiation that occur at different locations along the Z-axis. Signals of the electromagnetic radiation, each being frequency modulated by a frequency of the ultrasound radiation, are detected, to thereby enabling the imaging of the region of interest.
PCT/IL2001/000674 2000-07-23 2001-07-23 Apparatus and method for probing light absorbing agents in biological tissues WO2002008740A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US10/333,684 US6815694B2 (en) 2000-07-23 2001-07-23 Apparatus and method for probing light absorbing agents in biological tissues
DE60106270T DE60106270T2 (en) 2000-07-23 2001-07-23 METHOD AND DEVICE FOR TESTING LIGHT ABSORBING MEDICINES IN BIOLOGICAL TISSUE
AU2001278665A AU2001278665A1 (en) 2000-07-23 2001-07-23 Apparatus and method for probing light absorbing agents in biological tissues
AT01956750T ATE278947T1 (en) 2000-07-23 2001-07-23 METHOD AND APPARATUS FOR TESTING LIGHT ABSORBING AGENTS IN BIOLOGICAL TISSUE
EP01956750A EP1303756B1 (en) 2000-07-23 2001-07-23 Apparatus and method for probing light absorbing agents in biological tissues

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL137447A IL137447A (en) 2000-07-23 2000-07-23 Apparatus and method for probing light absorbing agents in biological tissues
IL137447 2000-07-23

Publications (2)

Publication Number Publication Date
WO2002008740A2 WO2002008740A2 (en) 2002-01-31
WO2002008740A3 true WO2002008740A3 (en) 2003-01-23

Family

ID=11074428

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2001/000674 WO2002008740A2 (en) 2000-07-23 2001-07-23 Apparatus and method for probing light absorbing agents in biological tissues

Country Status (7)

Country Link
US (1) US6815694B2 (en)
EP (1) EP1303756B1 (en)
AT (1) ATE278947T1 (en)
AU (1) AU2001278665A1 (en)
DE (1) DE60106270T2 (en)
IL (1) IL137447A (en)
WO (1) WO2002008740A2 (en)

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JP5847841B2 (en) 2011-01-06 2016-01-27 アプライド マテリアルズ イスラエル リミテッド Method and system for coherence reduction
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Also Published As

Publication number Publication date
AU2001278665A1 (en) 2002-02-05
IL137447A0 (en) 2001-07-24
US6815694B2 (en) 2004-11-09
DE60106270D1 (en) 2004-11-11
EP1303756A2 (en) 2003-04-23
IL137447A (en) 2007-03-08
ATE278947T1 (en) 2004-10-15
US20040099815A1 (en) 2004-05-27
EP1303756B1 (en) 2004-10-06
DE60106270T2 (en) 2005-09-08
WO2002008740A2 (en) 2002-01-31

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