WO2002009597A3 - Diaphysial cortical dowel - Google Patents

Diaphysial cortical dowel Download PDF

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Publication number
WO2002009597A3
WO2002009597A3 PCT/US2001/024145 US0124145W WO0209597A3 WO 2002009597 A3 WO2002009597 A3 WO 2002009597A3 US 0124145 W US0124145 W US 0124145W WO 0209597 A3 WO0209597 A3 WO 0209597A3
Authority
WO
WIPO (PCT)
Prior art keywords
dowel
intra
biologically active
active substances
implants
Prior art date
Application number
PCT/US2001/024145
Other languages
French (fr)
Other versions
WO2002009597A2 (en
Inventor
Russell S Donda
Nicholas E Grivas
Jamie M Grooms
Kevin C Carter
Original Assignee
Regeneration Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneration Tech Inc filed Critical Regeneration Tech Inc
Priority to AU2001280962A priority Critical patent/AU2001280962A1/en
Publication of WO2002009597A2 publication Critical patent/WO2002009597A2/en
Publication of WO2002009597A3 publication Critical patent/WO2002009597A3/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0017—Angular shapes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0017—Angular shapes
    • A61F2230/0019—Angular shapes rectangular
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028—Shapes in the form of latin or greek characters
    • A61F2230/0034—D-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0067—Three-dimensional shapes conical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0069—Three-dimensional shapes cylindrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0082—Three-dimensional shapes parallelepipedal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
    • A61F2250/0097—Visible markings, e.g. indicia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00976—Coating or prosthesis-covering structure made of proteins or of polypeptides, e.g. of bone morphogenic proteins BMP or of transforming growth factors TGF

Abstract

A dowel (800) is provided by obtaining a plug from the shaft (diaphysis) of various long bones. The dowel (800) has an intra-medullary canal (30), which can be packed with any of a variety of osteogenic materials. The dowel (800) has a cortical surface (10) into which an instrument attachment hole (15) may be machined and onto which an alignment mark (16) may be inscribed for proper orientation of the intra-medullary canal (30). The dowel (800) has a chamfered insertion end (822) and has improved biomechanical and vertebral fusion induction properties as compared to standard dowels known in the art. Also disclosed herein are various implants that comprise a plurality of holes (810) to aid in the delivery of biologically active substances associated with said implants. The implant (800) may further be infused, embedded soaked or coated, or combinations thereof, with biologically active substances selected from growth factors, bone morphogenetic proteins, cells, antibiotics, proteins, peptides, and nucleic acids.
PCT/US2001/024145 2000-08-01 2001-08-01 Diaphysial cortical dowel WO2002009597A2 (en)

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AU2001280962A AU2001280962A1 (en) 2000-08-01 2001-08-01 Diaphysial cortical dowel

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US63017900A 2000-08-01 2000-08-01
US09/630,179 2000-08-01

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WO2002009597A3 true WO2002009597A3 (en) 2002-08-08

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6648894B2 (en) 2000-12-21 2003-11-18 Stryker Spine Bone graft forming guide and method of forming bone grafts
CN1303950C (en) * 2004-01-08 2007-03-14 东南大学 Cervical vertebra pyramid microfrauma fusion apparatus
US8278094B2 (en) 2005-12-14 2012-10-02 The Invention Science Fund I, Llc Bone semi-permeable device
US9061075B2 (en) 2005-12-14 2015-06-23 The Invention Science Fund I, Llc Bone delivery device
US8682619B2 (en) 2005-12-14 2014-03-25 The Invention Science Fund I, Llc Device including altered microorganisms, and methods and systems of use
US8354258B2 (en) 2005-12-14 2013-01-15 The Invention Science Fund I, Llc Diatom device
US8900865B2 (en) * 2005-12-14 2014-12-02 The Invention Science Fund I, Llc Blood brain barrier device
US8367384B2 (en) 2005-12-14 2013-02-05 The Invention Science Fund I, Llc Bone semi-permeable device
US8198080B2 (en) 2005-12-14 2012-06-12 The Invention Science Fund I, Llc Bone delivery device
US9005944B2 (en) 2005-12-14 2015-04-14 The Invention Science Fund I, Llc Bone cell delivery device
US8734823B2 (en) 2005-12-14 2014-05-27 The Invention Science Fund I, Llc Device including altered microorganisms, and methods and systems of use
US8469964B2 (en) * 2006-05-10 2013-06-25 Warsaw Orthopedic, Inc. Bone cutting template and method of treating bone fractures
CA2793185C (en) 2010-03-16 2019-02-12 Pinnacle Spine Group, Llc Intervertebral implants and graft delivery systems and methods
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WO2014159739A1 (en) 2013-03-14 2014-10-02 Pinnacle Spine Group, Llc Interbody implants and graft delivery systems
WO2016044053A1 (en) 2014-09-19 2016-03-24 Crossroads Extremity Systems, Llc Bone fixation implant and means of fixation
WO2021076245A1 (en) 2019-10-18 2021-04-22 Sparta Biopharma LLC Connective tissue to bone interface scaffolds
US20230364304A1 (en) 2020-08-24 2023-11-16 Sparta Biopharma LLC Methods of forming bone interface scaffolds

Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501269A (en) * 1981-12-11 1985-02-26 Washington State University Research Foundation, Inc. Process for fusing bone joints
GB2148122A (en) * 1983-09-30 1985-05-30 Gendler El Process for stimulating induction of bone formation and stimulation of bone regeneration by artificially perforated bone matrix
WO1989004646A1 (en) * 1987-11-13 1989-06-01 Jefferies Steven R Bone repair material and delayed drug delivery
US5112354A (en) * 1989-11-16 1992-05-12 Northwestern University Bone allograft material and method
WO1995028973A1 (en) * 1994-04-27 1995-11-02 Board Of Regents, The University Of Texas System Porous prosthesis with biodegradable material impregnated intersticial spaces
EP0732093A2 (en) * 1995-02-17 1996-09-18 Sofamor Danek Group, Inc. Interbody spinal fusion implants
WO1996040019A1 (en) * 1995-06-07 1996-12-19 Michelson Gary K Frusto-conical interbody spinal fusion implants
WO1996039988A2 (en) * 1995-06-07 1996-12-19 Michelson Gary K Translateral spinal implant
US5609635A (en) * 1988-06-28 1997-03-11 Michelson; Gary K. Lordotic interbody spinal fusion implants
WO1997025945A1 (en) * 1996-01-16 1997-07-24 University Of Florida, Tissue Bank, Inc. Diaphysial cortical dowel
EP0806212A1 (en) * 1996-05-10 1997-11-12 Matrix Medical B.V. Device for incorporation and release of biologically active agents
WO1998017209A2 (en) * 1996-10-23 1998-04-30 Sdgi Holdings, Inc. Spinal spacer
WO1998040113A1 (en) * 1997-03-13 1998-09-17 University Of Florida Tissue Bank, Inc. Bone paste
WO1998055052A1 (en) * 1997-06-03 1998-12-10 Sdgi Holdings, Inc. Open intervertebral spacer
WO1999009914A1 (en) * 1997-08-27 1999-03-04 University Of Florida Tissue Bank, Inc. Cortical bone cervical smith-robinson fusion implant
WO1999021515A1 (en) * 1997-10-27 1999-05-06 University Of Florida Tissue Bank, Inc. Segmentally demineralized bone implant
WO1999051171A1 (en) * 1998-04-07 1999-10-14 Macropore, Inc. Membrane with tissue-guiding surface corrugations
WO2000025707A1 (en) * 1998-10-30 2000-05-11 Michelson Gary K Self-broaching, rotatable, push-in interbody fusion implant and method for deployment thereof
WO2000040177A1 (en) * 1999-01-05 2000-07-13 Lifenet Composite bone graft, method of making and using same
WO2000041654A2 (en) * 1999-01-11 2000-07-20 Sdgi Holdings, Inc. Truncated open intervertebral spacers

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5053049A (en) 1985-05-29 1991-10-01 Baxter International Flexible prostheses of predetermined shapes and process for making same
US4627853A (en) 1985-05-29 1986-12-09 American Hospital Supply Corporation Method of producing prostheses for replacement of articular cartilage and prostheses so produced
US5015247A (en) 1988-06-13 1991-05-14 Michelson Gary K Threaded spinal implant
US5811094A (en) 1990-11-16 1998-09-22 Osiris Therapeutics, Inc. Connective tissue regeneration using human mesenchymal stem cell preparations
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5306303A (en) 1991-11-19 1994-04-26 The Medical College Of Wisconsin, Inc. Bone induction method
US5171279A (en) 1992-03-17 1992-12-15 Danek Medical Method for subcutaneous suprafascial pedicular internal fixation

Patent Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501269A (en) * 1981-12-11 1985-02-26 Washington State University Research Foundation, Inc. Process for fusing bone joints
GB2148122A (en) * 1983-09-30 1985-05-30 Gendler El Process for stimulating induction of bone formation and stimulation of bone regeneration by artificially perforated bone matrix
WO1989004646A1 (en) * 1987-11-13 1989-06-01 Jefferies Steven R Bone repair material and delayed drug delivery
US5609635A (en) * 1988-06-28 1997-03-11 Michelson; Gary K. Lordotic interbody spinal fusion implants
US5112354A (en) * 1989-11-16 1992-05-12 Northwestern University Bone allograft material and method
WO1995028973A1 (en) * 1994-04-27 1995-11-02 Board Of Regents, The University Of Texas System Porous prosthesis with biodegradable material impregnated intersticial spaces
EP0732093A2 (en) * 1995-02-17 1996-09-18 Sofamor Danek Group, Inc. Interbody spinal fusion implants
WO1996040019A1 (en) * 1995-06-07 1996-12-19 Michelson Gary K Frusto-conical interbody spinal fusion implants
WO1996039988A2 (en) * 1995-06-07 1996-12-19 Michelson Gary K Translateral spinal implant
WO1997025945A1 (en) * 1996-01-16 1997-07-24 University Of Florida, Tissue Bank, Inc. Diaphysial cortical dowel
EP0806212A1 (en) * 1996-05-10 1997-11-12 Matrix Medical B.V. Device for incorporation and release of biologically active agents
WO1998017209A2 (en) * 1996-10-23 1998-04-30 Sdgi Holdings, Inc. Spinal spacer
WO1998040113A1 (en) * 1997-03-13 1998-09-17 University Of Florida Tissue Bank, Inc. Bone paste
WO1998055052A1 (en) * 1997-06-03 1998-12-10 Sdgi Holdings, Inc. Open intervertebral spacer
WO1999009914A1 (en) * 1997-08-27 1999-03-04 University Of Florida Tissue Bank, Inc. Cortical bone cervical smith-robinson fusion implant
WO1999021515A1 (en) * 1997-10-27 1999-05-06 University Of Florida Tissue Bank, Inc. Segmentally demineralized bone implant
WO1999051171A1 (en) * 1998-04-07 1999-10-14 Macropore, Inc. Membrane with tissue-guiding surface corrugations
WO2000025707A1 (en) * 1998-10-30 2000-05-11 Michelson Gary K Self-broaching, rotatable, push-in interbody fusion implant and method for deployment thereof
WO2000040177A1 (en) * 1999-01-05 2000-07-13 Lifenet Composite bone graft, method of making and using same
WO2000041654A2 (en) * 1999-01-11 2000-07-20 Sdgi Holdings, Inc. Truncated open intervertebral spacers

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