WO2002022185A3 - Method for treating a patient using a cultured connective tissue construct - Google Patents

Method for treating a patient using a cultured connective tissue construct Download PDF

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Publication number
WO2002022185A3
WO2002022185A3 PCT/US2001/029323 US0129323W WO0222185A3 WO 2002022185 A3 WO2002022185 A3 WO 2002022185A3 US 0129323 W US0129323 W US 0129323W WO 0222185 A3 WO0222185 A3 WO 0222185A3
Authority
WO
WIPO (PCT)
Prior art keywords
connective tissue
tissue construct
patient
treating
cultured
Prior art date
Application number
PCT/US2001/029323
Other languages
French (fr)
Other versions
WO2002022185A2 (en
Inventor
Nancy L Parenteau
James T Robertson
Original Assignee
Organogenesis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organogenesis Inc filed Critical Organogenesis Inc
Priority to DE60128933T priority Critical patent/DE60128933T2/en
Priority to CA2422861A priority patent/CA2422861C/en
Priority to MXPA03002415A priority patent/MXPA03002415A/en
Priority to AU9459501A priority patent/AU9459501A/en
Priority to EP01975255A priority patent/EP1320391B1/en
Priority to AU2001294595A priority patent/AU2001294595B2/en
Publication of WO2002022185A2 publication Critical patent/WO2002022185A2/en
Publication of WO2002022185A3 publication Critical patent/WO2002022185A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A61L27/3654—Cartilage, e.g. meniscus
    • A61L27/3658—Intervertebral discs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3852—Cartilage, e.g. meniscus
    • A61L27/3856—Intervertebral discs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3878—Nerve tissue, brain, spinal cord, nerves, dura mater
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

Abstract

The invention is directed to a method of tissue replacement and repair using a cultured bioremodelable connective tissue construct. The invention is specifically directed to a method for repairing annulus fibrosis of the intervertebral disc, after discectomy surgery where the annulus fibrosis has been opened, with a cultured bioremodelable connective tissue construct.
PCT/US2001/029323 2000-09-18 2001-09-18 Method for treating a patient using a cultured connective tissue construct WO2002022185A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DE60128933T DE60128933T2 (en) 2000-09-18 2001-09-18 METHOD OF TREATING A PATIENT WITH A CULTURED BIND WEAVE CONSTRUCTURE
CA2422861A CA2422861C (en) 2000-09-18 2001-09-18 Method for treating a patient using a cultured connective tissue construct
MXPA03002415A MXPA03002415A (en) 2000-09-18 2001-09-18 Method for treating a patient using a cultured connective tissue construct.
AU9459501A AU9459501A (en) 2000-09-18 2001-09-18 Method for treating a patient using a cultured connective tissue construct
EP01975255A EP1320391B1 (en) 2000-09-18 2001-09-18 Method for treating a patient using a cultured connective tissue construct
AU2001294595A AU2001294595B2 (en) 2000-09-18 2001-09-18 Method for treating a patient using a cultured connective tissue construct

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23340100P 2000-09-18 2000-09-18
US60/233,401 2000-09-18

Publications (2)

Publication Number Publication Date
WO2002022185A2 WO2002022185A2 (en) 2002-03-21
WO2002022185A3 true WO2002022185A3 (en) 2002-05-30

Family

ID=22877096

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/029323 WO2002022185A2 (en) 2000-09-18 2001-09-18 Method for treating a patient using a cultured connective tissue construct

Country Status (9)

Country Link
US (1) US7597712B2 (en)
EP (1) EP1320391B1 (en)
AT (1) ATE364410T1 (en)
AU (2) AU2001294595B2 (en)
CA (2) CA2774204C (en)
DE (1) DE60128933T2 (en)
ES (1) ES2288995T3 (en)
MX (1) MXPA03002415A (en)
WO (1) WO2002022185A2 (en)

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US7357798B2 (en) * 1996-07-16 2008-04-15 Arthrocare Corporation Systems and methods for electrosurgical prevention of disc herniations
US8632590B2 (en) 1999-10-20 2014-01-21 Anulex Technologies, Inc. Apparatus and methods for the treatment of the intervertebral disc
US7004970B2 (en) 1999-10-20 2006-02-28 Anulex Technologies, Inc. Methods and devices for spinal disc annulus reconstruction and repair
US7052516B2 (en) 1999-10-20 2006-05-30 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and deformable spinal disc annulus stent
US20030153976A1 (en) * 1999-10-20 2003-08-14 Cauthen Joseph C. Spinal disc annulus reconstruction method and spinal disc annulus stent
US7951201B2 (en) 1999-10-20 2011-05-31 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7935147B2 (en) 1999-10-20 2011-05-03 Anulex Technologies, Inc. Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus
US6592625B2 (en) * 1999-10-20 2003-07-15 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
US8128698B2 (en) 1999-10-20 2012-03-06 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7615076B2 (en) 1999-10-20 2009-11-10 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US6805695B2 (en) 2000-04-04 2004-10-19 Spinalabs, Llc Devices and methods for annular repair of intervertebral discs
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FR2812185B1 (en) 2000-07-25 2003-02-28 Spine Next Sa SEMI-RIGID CONNECTION PIECE FOR RACHIS STABILIZATION
US20030130738A1 (en) * 2001-11-08 2003-07-10 Arthrocare Corporation System and method for repairing a damaged intervertebral disc
US20070003525A1 (en) * 2003-01-31 2007-01-04 Moehlenbruck Jeffrey W Hydrogel compositions comprising nucleus pulposus tissue
US20040193274A1 (en) * 2003-03-28 2004-09-30 Trieu Hai H. Materials and methods for augmenting and/or repairing intervertebral discs
US7794456B2 (en) 2003-05-13 2010-09-14 Arthrocare Corporation Systems and methods for electrosurgical intervertebral disc replacement
US7708733B2 (en) 2003-10-20 2010-05-04 Arthrocare Corporation Electrosurgical method and apparatus for removing tissue within a bone body
US8148150B2 (en) * 2003-12-12 2012-04-03 Co.Don Ag Method for the production of intervertebral disk cell transplants and their use as transplantation material
US20070233274A1 (en) * 2004-04-12 2007-10-04 Hideyuki Miyake Artificial Tissue and Process for Producing the Same
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
US8568761B2 (en) * 2005-07-15 2013-10-29 Cormatrix Cardiovascular, Inc. Compositions for regenerating defective or absent myocardium
US20070027543A1 (en) * 2005-08-01 2007-02-01 Gimble Jeffrey M Use of adipose tissue-derived stromal cells in spinal fusion
US7879034B2 (en) 2006-03-02 2011-02-01 Arthrocare Corporation Internally located return electrode electrosurgical apparatus, system and method
US20080065218A1 (en) * 2006-09-13 2008-03-13 O'neil Michael J Annulus fibrosus repair devices and techniques
US20080082170A1 (en) * 2006-09-29 2008-04-03 Peterman Marc M Apparatus and methods for surgical repair
US20080172126A1 (en) * 2006-10-03 2008-07-17 Reynolds Martin A Nucleus pulposus injection devices and methods
WO2008060822A2 (en) * 2006-10-20 2008-05-22 Keracure, Inc. Devices with cells cultured on flexible supports
WO2009043052A1 (en) * 2007-09-27 2009-04-02 Columbia University Methods and systems for forming biocompatible materials
WO2009086535A2 (en) * 2007-12-27 2009-07-09 The Trustees Of Columbia University In The City Of New York Systems and methods for forming patterned extracellular matrix materials
US8163022B2 (en) 2008-10-14 2012-04-24 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US20100160968A1 (en) * 2008-12-19 2010-06-24 Abbott Spine Inc. Systems and methods for pedicle screw-based spine stabilization using flexible bands
US9044335B2 (en) 2009-05-05 2015-06-02 Cornell University Composite tissue-engineered intervertebral disc with self-assembled annular alignment
WO2011050107A2 (en) * 2009-10-20 2011-04-28 Cns Delivery Systems Compositions and methods for delivery of therapeutic agents to the cns
US8460319B2 (en) 2010-01-11 2013-06-11 Anulex Technologies, Inc. Intervertebral disc annulus repair system and method
US8979838B2 (en) 2010-05-24 2015-03-17 Arthrocare Corporation Symmetric switching electrode method and related system
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Also Published As

Publication number Publication date
DE60128933T2 (en) 2008-02-14
EP1320391B1 (en) 2007-06-13
US20020082698A1 (en) 2002-06-27
US7597712B2 (en) 2009-10-06
ES2288995T3 (en) 2008-02-01
MXPA03002415A (en) 2004-07-08
ATE364410T1 (en) 2007-07-15
CA2422861C (en) 2012-06-19
CA2774204C (en) 2013-10-08
CA2774204A1 (en) 2002-03-21
AU2001294595B2 (en) 2007-03-29
AU9459501A (en) 2002-03-26
DE60128933D1 (en) 2007-07-26
WO2002022185A2 (en) 2002-03-21
CA2422861A1 (en) 2002-03-21
EP1320391A2 (en) 2003-06-25

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