WO2002040630A3 - Process of decellularizing biological matrices and acellular biological matrices useful in tissue engineering - Google Patents
Process of decellularizing biological matrices and acellular biological matrices useful in tissue engineering Download PDFInfo
- Publication number
- WO2002040630A3 WO2002040630A3 PCT/IL2001/001060 IL0101060W WO0240630A3 WO 2002040630 A3 WO2002040630 A3 WO 2002040630A3 IL 0101060 W IL0101060 W IL 0101060W WO 0240630 A3 WO0240630 A3 WO 0240630A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- biological matrices
- acellular
- decellularizing
- biological matrix
- tissue engineering
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002224003A AU2002224003A1 (en) | 2000-11-15 | 2001-11-15 | Process of decellularizing biological matrices and acellular biological matrices useful in tissue engineering |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL13970800A IL139708A0 (en) | 2000-11-15 | 2000-11-15 | Process of decellularizing biological matrices and acellular biological matrices useful in tissue engineering |
IL139708 | 2000-11-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002040630A2 WO2002040630A2 (en) | 2002-05-23 |
WO2002040630A3 true WO2002040630A3 (en) | 2004-06-10 |
Family
ID=11074822
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IL2001/001060 WO2002040630A2 (en) | 2000-11-15 | 2001-11-15 | Process of decellularizing biological matrices and acellular biological matrices useful in tissue engineering |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2002224003A1 (en) |
IL (1) | IL139708A0 (en) |
WO (1) | WO2002040630A2 (en) |
Cited By (1)
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KR101595108B1 (en) | 2006-10-06 | 2016-02-18 | 안트로제네시스 코포레이션 | Nativetelopeptide Placental Collagen Compositions |
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JP4092397B2 (en) * | 2002-09-10 | 2008-05-28 | 国立循環器病センター総長 | Treatment of living tissue for transplantation by applying ultrahigh hydrostatic pressure |
US7459154B2 (en) * | 2002-12-26 | 2008-12-02 | Cell Genesys, Inc. | Methods and reagents for the enhancement of virus transduction in the bladder epithelium |
AU2004270239C1 (en) | 2003-09-04 | 2011-07-07 | Cook Biotech Incorporated | Extracellular matrix composite materials, and manufacture and use thereof |
WO2006073626A2 (en) * | 2005-01-05 | 2006-07-13 | The Cleveland Clinic Foundation | Method for fixing tissue |
US8454678B2 (en) | 2005-03-19 | 2013-06-04 | Cook Biotech Incorporated | Prosthetic implants including ECM composite material |
EP1902127B1 (en) * | 2005-04-15 | 2012-08-29 | Wake Forest University Health Sciences | Bioreactor system and method of enhancing functionality of muscle cultured in vitro |
EP1719533A1 (en) * | 2005-05-04 | 2006-11-08 | Tecnobiomedica S.p.A. | Method of preparing acellularized, biocompatible, implantable material |
US9072816B2 (en) * | 2006-01-18 | 2015-07-07 | Cormatrix Cardiovascular, Inc. | Composition for modulating inflammation of cardiovascular tissue |
US8568761B2 (en) * | 2005-07-15 | 2013-10-29 | Cormatrix Cardiovascular, Inc. | Compositions for regenerating defective or absent myocardium |
PL1928519T3 (en) | 2005-08-26 | 2012-08-31 | Univ Minnesota | Decellularization and recellularization of organs and tissues |
WO2007056547A2 (en) * | 2005-11-08 | 2007-05-18 | Georgia Tech Research Corporation | Acellularized biomaterial from embryonic stem cells |
US20160082153A1 (en) * | 2006-01-18 | 2016-03-24 | Cormatrix Cardiovascular, Inc. | Method and System for Treatment of Damaged Biological Tissue |
GB0606231D0 (en) | 2006-03-29 | 2006-05-10 | Univ Leeds | Improvements relating to decellurisation of tissue matrices for bladder implantation |
AU2013203211B2 (en) * | 2006-10-06 | 2015-05-28 | Celularity Inc. | Native (telopeptide) placental collagen compositions |
EP2079490B1 (en) | 2006-10-23 | 2012-08-29 | Cook Biotech Incorporated | Processed ecm materials with enhanced component profiles |
CZ301086B6 (en) * | 2007-10-17 | 2009-11-04 | Bio-Skin, A. S. | Sterile autogenous, allogenic or xenogenic implant and process for preparing thereof |
EP3744357A1 (en) * | 2008-08-14 | 2020-12-02 | 3M Innovative Properties Company | Tissue scaffolds |
PL2588592T3 (en) * | 2010-06-30 | 2018-07-31 | Miromatrix Medical Inc. | Use of perfusion decellularized organs for matched recellularization |
US10233420B2 (en) | 2010-09-01 | 2019-03-19 | Regents Of The University Of Minnesota | Methods of recellularizing a tissue or organ for improved transplantability |
EP3011936B8 (en) | 2011-01-06 | 2019-07-24 | Humacyte, Inc. | Tissue-engineered constructs |
US20130013083A1 (en) * | 2011-01-06 | 2013-01-10 | Humacyte | Tissue-Engineered Constructs |
AU2012262311B2 (en) | 2011-05-31 | 2016-04-28 | Lifecell Corporation | Adipose tissue matrices |
EP2805164B1 (en) * | 2012-01-16 | 2017-11-08 | Koninklijke Philips N.V. | Determining a presence of target molecules in a body fluid comprising cells |
WO2013134009A1 (en) | 2012-03-08 | 2013-09-12 | Lifecell Corporation | Enzyme-activated collagen and tissue matrices |
US9290738B2 (en) | 2012-06-13 | 2016-03-22 | Miromatrix Medical Inc. | Methods of decellularizing bone |
US10363343B2 (en) | 2012-07-05 | 2019-07-30 | Lifecell Corporation | Tissue-based drain manifolds |
CN103536967B (en) * | 2012-07-10 | 2016-04-13 | 上海微创医疗器械(集团)有限公司 | A kind of method for removing cells preparing extracellular matrix support material |
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US10035980B2 (en) | 2013-01-14 | 2018-07-31 | Florida State University Research Foundation, Inc. | Extracellular matrix derived from stem cells and methods for production |
ES2831756T3 (en) | 2013-03-15 | 2021-06-09 | Miromatrix Medical Inc | Use of perfusion decellularized liver for recellularization of islet cells |
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CN105013014A (en) * | 2015-07-31 | 2015-11-04 | 武汉蓝普医品有限公司 | Preparation method and application of acellular matrix biological material |
CN105920670A (en) * | 2016-05-19 | 2016-09-07 | 李世荣 | Degradable male genital organ patch composite material with biological elasticity and preparation method thereof |
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WO2018009428A1 (en) | 2016-07-05 | 2018-01-11 | Lifecell Corporation | Tissue matrices incorporating multiple tissue types |
US11278643B2 (en) | 2016-09-06 | 2022-03-22 | Mayo Foundation For Medical Education And Research | Use of resected liver serum for whole liver-engineering |
US20200222589A1 (en) * | 2017-05-30 | 2020-07-16 | Adeka Corporation | Method for producing decellularized material for transplantation and graft composition consisting of biocompatible material including said material |
CN107596446B (en) * | 2017-09-16 | 2020-07-28 | 温州医科大学 | Decellularization kit for maintaining tissue ultrastructure and nutrition microenvironment |
CN115252910A (en) | 2017-10-18 | 2022-11-01 | 生命细胞公司 | Adipose tissue products and methods of production |
US11123375B2 (en) | 2017-10-18 | 2021-09-21 | Lifecell Corporation | Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products |
US11246994B2 (en) | 2017-10-19 | 2022-02-15 | Lifecell Corporation | Methods for introduction of flowable acellular tissue matrix products into a hand |
EP3697462B1 (en) | 2017-10-19 | 2023-07-12 | LifeCell Corporation | Flowable acellular tissue matrix products and methods of production |
CN110876816A (en) * | 2018-09-06 | 2020-03-13 | 韩嫣 | Pig bladder source bioactive repair material |
EP3976127A1 (en) | 2019-05-30 | 2022-04-06 | LifeCell Corporation | Biologic breast implant |
CN111569151B (en) * | 2020-05-12 | 2021-12-17 | 上海亚朋生物技术有限公司 | Acellular dermal matrix tissue engineering scaffold and preparation method thereof |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4776853A (en) * | 1986-07-28 | 1988-10-11 | Hsc Research Development Corporation | Process for preparing biological mammalian implants |
US5376110A (en) * | 1991-02-14 | 1994-12-27 | Baxter International Inc. | Method of manufacturing pliable biological grafts materials |
US5735902A (en) * | 1987-07-20 | 1998-04-07 | Regen Biologics, Inc. | Hand implant device |
US5855620A (en) * | 1995-04-19 | 1999-01-05 | St. Jude Medical, Inc. | Matrix substrate for a viable body tissue-derived prosthesis and method for making the same |
US6042610A (en) * | 1987-07-20 | 2000-03-28 | Regen Biologics, Inc. | Meniscal augmentation device |
US6376244B1 (en) * | 1999-12-29 | 2002-04-23 | Children's Medical Center Corporation | Methods and compositions for organ decellularization |
-
2000
- 2000-11-15 IL IL13970800A patent/IL139708A0/en unknown
-
2001
- 2001-11-15 AU AU2002224003A patent/AU2002224003A1/en not_active Abandoned
- 2001-11-15 WO PCT/IL2001/001060 patent/WO2002040630A2/en not_active Application Discontinuation
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4776853A (en) * | 1986-07-28 | 1988-10-11 | Hsc Research Development Corporation | Process for preparing biological mammalian implants |
US5735902A (en) * | 1987-07-20 | 1998-04-07 | Regen Biologics, Inc. | Hand implant device |
US6042610A (en) * | 1987-07-20 | 2000-03-28 | Regen Biologics, Inc. | Meniscal augmentation device |
US5376110A (en) * | 1991-02-14 | 1994-12-27 | Baxter International Inc. | Method of manufacturing pliable biological grafts materials |
US5855620A (en) * | 1995-04-19 | 1999-01-05 | St. Jude Medical, Inc. | Matrix substrate for a viable body tissue-derived prosthesis and method for making the same |
US6376244B1 (en) * | 1999-12-29 | 2002-04-23 | Children's Medical Center Corporation | Methods and compositions for organ decellularization |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101595108B1 (en) | 2006-10-06 | 2016-02-18 | 안트로제네시스 코포레이션 | Nativetelopeptide Placental Collagen Compositions |
KR101644985B1 (en) | 2006-10-06 | 2016-08-02 | 안트로제네시스 코포레이션 | Native(telopeptide) Placental Collagen Compositions |
Also Published As
Publication number | Publication date |
---|---|
AU2002224003A1 (en) | 2002-05-27 |
IL139708A0 (en) | 2002-02-10 |
WO2002040630A2 (en) | 2002-05-23 |
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