WO2002049539A2 - Dynamic implanted intervertebral spacer - Google Patents

Dynamic implanted intervertebral spacer Download PDF

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Publication number
WO2002049539A2
WO2002049539A2 PCT/US2001/048004 US0148004W WO0249539A2 WO 2002049539 A2 WO2002049539 A2 WO 2002049539A2 US 0148004 W US0148004 W US 0148004W WO 0249539 A2 WO0249539 A2 WO 0249539A2
Authority
WO
WIPO (PCT)
Prior art keywords
spacer
tail pieces
elongated
bone
barb
Prior art date
Application number
PCT/US2001/048004
Other languages
French (fr)
Other versions
WO2002049539A3 (en
Inventor
Salvatore Castro
Original Assignee
Cortek, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cortek, Inc. filed Critical Cortek, Inc.
Priority to AU2002229008A priority Critical patent/AU2002229008A1/en
Priority to EP01990138A priority patent/EP1343440B1/en
Priority to DE60128391T priority patent/DE60128391T2/en
Publication of WO2002049539A2 publication Critical patent/WO2002049539A2/en
Publication of WO2002049539A3 publication Critical patent/WO2002049539A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2/30965Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2835Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/286Bone stimulation by mechanical vibrations for enhancing ossification
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
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    • A61F2002/30112Rounded shapes, e.g. with rounded corners
    • A61F2002/30131Rounded shapes, e.g. with rounded corners horseshoe- or crescent- or C-shaped or U-shaped
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2002/30159Concave polygonal shapes
    • A61F2002/30168L-shaped
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30565Special structural features of bone or joint prostheses not otherwise provided for having spring elements
    • A61F2002/30571Leaf springs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30594Special structural features of bone or joint prostheses not otherwise provided for slotted, e.g. radial or meridian slot ending in a polar aperture, non-polar slots, horizontal or arcuate slots
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30604Special structural features of bone or joint prostheses not otherwise provided for modular
    • A61F2002/30616Sets comprising a plurality of prosthetic parts of different sizes or orientations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30841Sharp anchoring protrusions for impaction into the bone, e.g. sharp pins, spikes
    • A61F2002/30845Sharp anchoring protrusions for impaction into the bone, e.g. sharp pins, spikes with cutting edges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30878Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
    • A61F2002/30884Fins or wings, e.g. longitudinal wings for preventing rotation within the bone cavity
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2002/448Joints for the spine, e.g. vertebrae, spinal discs comprising multiple adjacent spinal implants within the same intervertebral space or within the same vertebra, e.g. comprising two adjacent spinal implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • A61F2230/0013Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
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Definitions

  • the present invention relates to implants for repair of spinal defects and injuries. It relates in particular to implants having utility to maintain intervertebral spacing after disc removal. It further relates to intervertebral spacers which can permit at least some remaining spinal flexibility.
  • Natural intervertebral spinal discs serve multiple purposes. The first, and perhaps most basic, is to preserve the anatomical spacing between adjacent vertebrae such that the spinal column and horizontally branching nerve bundles are allowed to function normally. A second major purpose is to allow relative flexural motion between adjacent vertebral bodies. Natural flexibility, at least of the upper spine, permits rotation about two horizontal axes and one vertical axis. Finally, the disc also serves as a shock absorber for columnar loading of the spine. However, mechanical trauma, degenerative disc disease, and other pathogenesis can compromise a disc's ability to maintain the spacing, facilitate flexibility, and provide the shock absorbing function.
  • interbody fusion wherein the disc is partially or wholly excised and living bone or various forms of calcium phosphate or other substrate material is placed within the space previously occupied by the disc for the purpose of restoring the normal separation, strength, and stability. Fusion is intended to provide healthy, living bone between the adjacent vertebrae.
  • the bone grafts have been available for anterior cervical fusion.
  • One type is a round dowel plug-like configuration, such as the original Cloward dowel.
  • the second type a rectangular plug in a rectangular hole, is often referred to as the Smith-Robinson technique.
  • the bone can be obtained from the patient's own iliac crest, from allograft cadaveric crest, or cut from a hard femoral cortical bone.
  • intervertebral spacers designed for installation between adjacent vertebrae have been patented. These include: U.S. Pat. No. 6,086,613 to CAMINO, et al, relates to intervertebral spacers used in connection with spinal fusion. U.S. Pat. No. 6,039,762 to McKay describes a spacer body having an outer surface and a height approximating the height of a human disc space, said body composed of a porous, biocompatible ceramic material for permitting tissue ingrowth therethrough. U.S. Pat. No. 5,989,291 to RALPH, et al.
  • an intervertebral spacer having a pair of opposing plates for seating against opposing vertebral bone surfaces, separated by at least one spring mechanism.
  • there are two Belleville washers which are oriented in opposite directions such that the narrow ends thereof are in contact with each other and the wider ends are in contact with the respective end plates.
  • the Belleville washers work as springs. (Belleville washers are described as frustoconical in shape.)
  • U.S. Pat. No. 5,984,922 to McKay describes a spinal fixation device consisting of an intervertebral body wedge which is inserted between vertebral bodies by sequentially expanding the disc space using a spacer. No posterior fixation devices are needed for stabilization of the vertebrae.
  • U.S. Pat. No. 5,888,222 to COATES, et al. describes a spinal spacer that engages adjacent vertebrae. The spacer includes a body having two ends, at least one of which "defines" an inferior vertebral engaging surface having a set of migration resistance grooves.
  • 5,534,029 to Shia discloses an articulated vertebral body spacer consisting of a pair of upper and lower joint pieces to be inserted between vertebrae. This spacer allows its components to pivot in accordance with forward/backward and bending motions of vertebral bodies.
  • U.S. Pat. No. 4,599,086 to Dogy discloses a spinal stabilization device positionable between separated but neighboring vertebrae. A wrench can be inserted into the opening until it engages a pair of pins, and then the wrench can be rotated to advance the pins into the abutting vertebral bodies.
  • U.S. Pat. No. 5,888,223 to BRAY, Jr. discloses an anterior fixation device consisting of an oval shaped hollow intervertebral spacer and a retaining plate.
  • the spacer has a side wall and superior and inferior walls.
  • the superior and inferior walls are dome-shaped and porous to allow bone to grow through the device to achieve fusion of two adjacent vertebral bodies;
  • U.S. Pat. No. 5,865,848 to Baker describing a spinal fusion implant assembly for spacing vertebrae.
  • the device includes a translation mechanism for providing relative motion between the components.
  • An additional area of prior art includes all devices designed to be applied to one or more exterior surfaces of the spine.
  • Such devices include all types of plates, struts, and rods which are attached by hooks, wires and screws.
  • Other devices are simply variations on the use of rods (e.g. Harrington, Luque, Cotrel-Dubosset, Zielke), wires or cables (Dwyer), plates and screws (Steffee), or struts (Dunn, Knowles).
  • a preferable spacer would at least to some extent preserve the ability of the patient to rotate portions of the spinal column about two perpendicular horizontal axes (and linear combinations thereof) and about the vertical axis. All of the prior art approaches suffer from the drawback that they either do not attempt to preserve such flexibility or they are unable in practice to achieve a workable device. In addition they suffer from other drawbacks.
  • Spacers have the drawback that, by themselves, they do not achieve the beneficial results of fusion. On the other hand, most of them are rigid, and therefore also have the same drawback as successful fusion, namely reducing the patient's flexibility.
  • Another object of the present invention is to provide an artificial disc prosthesis able to allow for full bending movement of the two vertebral bodies between which it is installed, allowing flexibility within both the lateral and sagittal planes.
  • Yet another object of the present invention is to provide an intervertebral implant device that can pierce the bony cortex of the vertebral bodied during installation.
  • Yet another object of the present invention is to provide an intervertebral implant device that provides the correct amount of loading in order to promote bone growth and vertebral fusion.
  • a final object of the invention is to provide a single-piece device which alone in the cervical region of the spine or in combination with a second like device in the lumbar region of the spine can be driven into an intervertebral space with a single force- applying operation for each of the one or two devices.
  • the present invention is an implantable intervertebral spacer designed to both preserve the space between adjacent vertebrae and to provide some continued spinal flexibility by virtue of its flexible construction.
  • This spacer is also characterized by single piece construction and by the property of being self guiding upon initial insertion into the intervertebral space.
  • This invention also has four spaced-apart tail pieces flexibly linked to one another, consisting of one upper set of two horizontally spaced-apart tail pieces and one lower set of two horizontally spaced-apart tail pieces, the upper and lower sets also being vertically spaced-apart from one another.
  • Each of the two upper spaced-apart elongated tail pieces is independently flexibly linked to each of the corresponding spaced apart elongated lower tail pieces.
  • Each of the tail pieces also comprises an elongated post supporting a bone gripping barb and a cutting edge having an inwardly angled facet.
  • the implant Upon installation between adjacent vertebral bodies, the implant is self locking by virtue of strain induced in the elongated barb-supporting posts.
  • the device is implantable as a single unit within the intervertebral space between adjacent cervical vertebrae or it is implantable in conjunction with a second spacer within the same intervertebral space.
  • the device Because of the cutting edges and barbs, it is implanted by being impacted with a driver device, at which point it is firmly seated and will not pull or creep out.
  • the device also has a wedge shaped front portion to guide it into the desired position during installation.
  • the bone gripping induced strain manifests within each of the elongated posts supporting each barb of each spaced-apart pair of barbs when the facet causes inward bending strain of the elongated posts upon installation into the vertebral bone.
  • the present invention is an implantable intervertebral device that can be configured also to promote bone growth and vertebral fusion.
  • the vertical slot between the upper and lower sets of the two horizontally spaced-apart tail pieces can be loaded with bone graft material and/or bone morphogenic protein so as to create a fusion column and promote intervertebral fusion. It is known that compressive loading of graft material promotes new bone growth and healing.
  • the horizontal slot between the upper and lower sets of tail pieces can be varied in height, and the radius of the internal void in the portion connecting the upper part of the device to the lower part of the device can be varied, both so as to provide flexing sufficient to produce enough loading on the graft material to promote bone growth and vertebral fusion while still providing sufficient compressive strength to maintain the necessary intervertebral spacing.
  • the spacer of the current invention can be fabricated from metal, preferably titanium or stainless steel. Or it can be fabricated from organic polymer such as thermoplastic or thermosetting plastic unfilled or filled with fibers such as glass, metal or carbon.
  • said implant spacer if fabricated from organic polymer, is to be fabricated from polyether ether ketone (PEEK), most preferably filled with fibers of metal or glass or, most preferably, carbon.
  • PEEK polyether ether ketone
  • a second embodiment of the said cervicalMumbar implant spacer employs the use of bullets situated upon elongated posts instead of barbs as a way to grip the vertebral bone. The forward cutting edge of each bullet has an angled facet that causes induced strain to arise within the elongated support post during installation.
  • FIGURE 1 is an oblique view of the cervical/lumbar implant spacer
  • FIGURE 2 A is a lateral orthogonal view of a single cervical/lumbar spacer inserted between two vertebrae;
  • FIGURE 2B is a sagittal orthogonal view of a single cervical/lumbar spacer inserted between two vertebrae;
  • FIGURE 3 A is a top view of the cervical/lumbar spacer
  • FIGURE 3B is a rear view of the cervical/lumbar spacer
  • FIGURE 3C is a side view of the cervical/lumbar spacer
  • FIGURE 4 is an oblique view of one embodiment of the cervical/lumbar implant spacer.
  • FIGURE 5 is an oblique view of a second embodiment of the cervical/lumbar implant spacer.
  • FIGURE 1 la ⁇ upper portion lb ⁇ lower portion
  • FIGURE 3B 2 dynamic cervical/lumbar spacer
  • the present invention known as the dynamic lumbar/cervical spacer, is an intervertebral implant device designed to perform one or a combination of three basic functions: (1) vertebral spacer; (2) spacer to be used in conjunction with vertebral fusion; and (3) artificial disc.
  • the said dynamic spacer is of single piece construction. It is self guiding upon initial insertion into the intervertebral space, and it is self locking upon installation between adjacent vertebral bodies. It is dynamic in the sense that it is designed to be flexible within both the sagittal and lateral planes; that is, subsequent to installation, the patient will be able to move in such a way that the vertebrae between which the spacer has been installed will be able to have some or all of the motions allowed by a natural and healthy intervertebral disc.
  • the dynamic spacer is provided with a pair of spaced apart cutting edges on the spacer's upper face and a similar pair of cutting edges on the spacer's lower face.
  • the respective pairs of spaced apart cutting edges enable the spacer to cut into the adjacent vertebral bodies upon being driven into the intervertebral disc space.
  • Each of the said cutting edges is furthermore provided with either “barbs” or “bullets” that inhibit subsequent movement or pullout of the spacer away from the vertebrae into which it has been driven.
  • each pair of cutting edges is geometrically arranged upon an elongated post so as to provide a grasping force, through induced strain within the elongated posts so as to hold the spacer within intimate contact with each respective vertebra to which it is attached.
  • the dynamic vertebral spacer of the present invention is designed to be installable by being impacted or otherwise driven or forced into place with a driver device.
  • the said spacer is also designed to be manufactured in a multiplicity of sizes and a multiplicity of proportions of length, width and height so as to accommodate a variety of intervertebral spacings and vertebral body sizes according to the needs of the patient.
  • the dynamic spacer is designed to also promote bone growth and intervertebral fusion.
  • the vertical slot between the upper and lower sets of the two horizontally spaced-apart tail pieces can be configures so that it can be loaded with graft to create a fusion column and promote fusion.
  • the horizontal slot between the upper and lower sets of tail pieces can be varied in height, and the radius of the inner void in the portion of the implant connecting the upper portions of the spacer to the lower portions of the spacer can also be varied, so as to provide enough flexing to produce loading on the graft sufficient to promote bone growth and vertebral fusion while also providing compressive strength sufficient to maintain the required separation of the adjacent vertebrae.
  • FIGURE 1 there is shown in oblique view one embodiment of a single dynamic cervical/lumbar spacer 2 according to the present invention.
  • the spacer 2 consists of a single piece body 4 having a wedge shaped front end 6 and four elongated tail pieces 7a, 7b, 7c and 7d flexibly attached to one another by way of the wedge shaped front end 6 located in the forward portion 9 of the spacer.
  • FIGURES 2A and 2B are orthogonal views of a single dynamic spacer according to the present invention inserted between the anterior portions of two vertebral bodies 20a, 20b.
  • the bone grabbing latching portions 8 of the spacer 2 are shown embedded within the adjacent vertebral bodies 20a, 20b. The dynamic features of the dynamic spacer 2 will become evident upon examination of the following additional FIGURES.
  • FIGURES 3 A, 3B and 3C show three orthogonal views of the dynamic spacer 2 shown in FIGURE 1.
  • FIGURE 3 A is a side view of the spacer 2 showing the single piece body 4 with the wedge shaped front end 6 and two of the four spaced apart and elongated tail pieces 7b, 7d separated from one another by the slot 16 and flexibly attached to one another by way of the wedge shaped front end 6.
  • the slot 16 terminates in the stress relieving circular portion 18 near the front region 6 of the spacer.
  • the bone gripping latching portions 8 are shown in FIGURE 3A being contiguous with the sharp forward cutting edge 10 and the medially inwardly angled facet 11 and the elongated bone engaging barb 14. More specifically, each bone latching portion 8 consists of an elongated support post 5a, 5b, 5c or 5d upon which is disposed the elongated bone engaging barb 14 having a forward cutting edge 10 with an angled facet 11.
  • FIGURE 3B Contemplation of the FIGURES 3 A, 3B and 3C will reveal to those skilled in the mechanical arts the dynamic aspect of the present vertebral spacer invention.
  • the respective elongated tail pieces 7a,7b,7c,7d are able to move flexurally in relation to one another.
  • the spacer 2 is shown after having been inserted into the intervertebral space 17, by being forced in or driven in by impact.
  • the four medially inwardly directed facets 11 of the bone gripping portions 8 engage the cortex bone the vertebral bodies 20a, 20b in such as way as to force medially inwards, towards one another, the respective pairs of spaced apart elongated posts 5a, 5b and 5c, 5d such that induced strain in the elongated posts, as well as in the region 15 between the respective pairs of elongated tail pieces 7a,7c and 7b,7d, forces the elongated barbs 14 into intimate gripping contact with the vertebral bone.
  • flexure of the region 15 necessarily forces together the respective pairs of tail pieces 7a,7c and 7b,7d, but primarily induces gripping strain in the respective pairs of elongated posts 5a, 5c and 5b, 5d.
  • the induced strain produces a laterally outwardly directed force that causes the elongated bone engaging barbs 14 to maintain in intimate contact with the vertebral bone.
  • the inventor recognizes that the vertical portions of the bone gripping latching portions 8 also undergo a small degree of flexure and thereby also have an induced strain that serves to secure the spacer 2 in intimate contact with the vertebral bodies 20a, 20b.
  • FIGURES 2 A and 2B show the spacer 2 implanted between the two vertebrae 20a, 20b.
  • FIGURE 2A shows the spacer 2 located more or less within the sagittal plane, with said the spacer being close to the anterior side of the vertebral bodies.
  • Such increasing separation of the anterior sides of the respective vertebral bodies 20a, 20b can be accommodated by the dynamic spacer 2 in that the elongated tail pieces 7a,7c (and 7b,7d, not shown) can flex apart from one another about the fulcrum 28 within the circular stress-relieving region 18 located in the forward portion 9 of the spacer.
  • the flexure of the tail pieces 7a,7c is indicated by the small arrows 24,26. It is important to note that during spinal flexure of the sort causing increasing separation of the vertebral bodies 20a, 20b that the bone gripping latching portions 8 remain tightly in contact with the respective vertebral bodies, according to the design function of the elongated bone engaging barbs 14.
  • the space between the anterior sides of the vertebral bodies 20a, 20b shown in FIGURE 2A decreases.
  • the two-headed arrow 22 would be reversed so as to indicate a coming together of the vertebral bodies.
  • the tail pieces, 7a,7c would also be forced into closer proximity about the fulcrum 28, and the orientation of the small motion indicating arrows 24a,24b would be reversed from that shown in FIGURE 2 A.
  • the fulcrum 28 can be seen to be a line (dotted) along the forwardmost side of the stress relieving region 18.
  • the line denoted by the callout number 28 in FIGURE 2B designates a zone of tension or compression as the whole forward region 9 of the spacer flexes in respective response to the increasing or decreasing separation of the upper tail pieces 7a,7b from the lower tail pieces 7c, 7d.
  • FIGURE 2B is a view of the implanted spacer from the anterior side of the spine, i.e., looking toward it from the front of the patient's body.
  • the pair of curved arrows 30,32 and the single two-headed arrow 34 illustrate the relative motion of the two vertebral bodies 20a, 20b if the patient were to bend laterally (specifically toward the patient's left side).
  • the right side of the vertebral bodies 20a, 20b become closer while the left side of the bodies move farther apart.
  • the spacer 2 is able to accommodate such motion because the tail pieces 7b, 7d on the right side of the FIGURE can flex into closer proximity, due to compression, while the tail pieces 7a, 7c on the left side move farther apart, due to tension.
  • FIGURE 4 shows in oblique view a first embodiment of the dynamic lumbar/cervical spacer 40 according to the present invention.
  • the spacer 40 is of single- piece construction. It consists of a wedge shaped front portion 42 and an upper set of two spaced apart elongated tail pieces 44a, 44b and a lower set of two spaced apart elongated tail pieces 44c, 44d. Each of the upper pair of spaced apart tail pieces 44a, 44b are independently flexibly linked to each of the corresponding spaced apart lower tail pieces 44c, 44d respectively.
  • the flexible link between the respective spaced apart upper tail pieces 44a, 44b and the corresponding lower tail pieces 44c, 44d is the front portion 42 containing a stress relieving circular region 46 at the forward end portion of the slot 47 separating the respective upper and lower pairs of tail pieces.
  • the upper portion 48a and lower portion 48b of the spacer 40 are symmetrical with one another about the horizontal plane defined by the plane of the slot 47.
  • 44b is able to move in the vertical direction, independently of the other, in relation to each of the corresponding two lower tail pieces 44c, 44d, thereby affording movement between the vertebrae (20a, 20b in FIGURES 2A, 2B) in both the lateral and the sagittal planes.
  • 44a, 44c from the right tail pieces 44b, 44d are two elongated posts 52a, 52c.
  • Each of the two elongated posts 52a, 52c is topped by an elongated barb 54a, 54c.
  • Corresponding elongated barbs 54b, 54d are disposed on the lower portion 44b of the spacer 40.
  • Facets 56 are disposed at the forward end of each elongated post and barb set, providing a sharp forward cutting edge 58 at the forward end of each of the four post and barb sets.
  • Each of the four facets 56 (only two are shown in the FIGURE) is angled in such a way that when the spacer 40 is forced between the vertebral bodies (20a, 20b in FIGURES 2A, 2B), the upper set of elongated posts 52a, 52b and the lower sets of elongated posts 52c, 52d are forced medially toward one another in such a way that strain is induced in the respective elongated posts so as to facilitate the ability of the elongated barbs 54a, 54b, 54c, 54d to remain in continuing firm contact with the vertebral bone (not shown in FIGURE 4).
  • a portion of medially directed strain in each set of the elongated posts 52a, 52b and 52c, 52d is born by the respective tail pieces 44a through 44d.
  • FIGURE 5 shows in oblique view a second embodiment of the dynamic lumbar/cervical spacer 60 according to the present invention.
  • the spacer 60 is of single- piece construction. It consists of a wedge shaped front portion 62 and an upper set of two spaced apart elongated tail pieces 64a, 64b and a lower set of two spaced apart elongated tail pieces 64c, 64d. Each of the upper pair of spaced apart tail pieces 64a, 64b are independently flexibly linked to each of the corresponding spaced apart lower tail pieces
  • the flexible link between the respective spaced apart upper tail pieces 64a, 64b and the corresponding lower tail pieces 64c, 64d is the front portion 62 containing a stress relieving circular region 66 at the forward end portion of the slot 67 separating the respective upper and lower pairs of tail pieces.
  • the upper portion 68a and lower portion 68b of the spacer 60 are symmetrical with one another about the horizontal plane defined by the plane of the slot 67.
  • Each of the two elongated upper tail pieces 64a, 64b is able to move in the vertical direction, independently of the other, in relation to each of the corresponding two lower tail pieces 64c, 64d, thereby affording movement between the vertebrae (20a, 20b in FIGURES 2A, 2B) in both the lateral and the sagittal planes.
  • Each of the two elongated posts 72a, 72c is topped by an elongated bullet 74a, 74c.
  • Corresponding elongated bullets 74b, 74d are disposed on the lower portion 68b of the spacer 60. Facets 76 are disposed at the forward end of each elongated post and bullet set, providing a sharp forward cutting edge 78 at the forward end of each of the four post and bullet sets.
  • Each of the four facets 76 (only two are shown in the FIGURE) is angled in such a way that when the spacer 60 is forced between the vertebral bodies (20a, 20b in FIGURES 2A, 2B), the upper set of elongated posts 72a, 72b and the lower sets of elongated posts 72c, 72d are forced medially toward one another in such a way that strain is induced in the respective elongated posts so as to facilitate the ability of the elongated bullets 74a, 74b, 74c, 74d to remain in continuing firm contact with the vertebral bone (not shown in FIGURE 5).
  • a portion of medially directed strain in each set of the elongated posts 72a, 72b and 72c, 72d is born by the respective tail pieces 64a through 64d.

Abstract

The invention is a single piece, self seating and locking dynamic intervertebral spacer (2). The dynamic spacer (2) is load-supporting by also able to undergo flexure in either or both the lateral and sagittal planes.

Description

DYNAMIC IMPLANTED INTERVERTEBRAL SPACER
PRIORITY This application is related to and claims priority from the United States Provisional
Application No. 60/256,632, filed December 19, 2000.
FIELD OF THE INVENTION
The present invention relates to implants for repair of spinal defects and injuries. It relates in particular to implants having utility to maintain intervertebral spacing after disc removal. It further relates to intervertebral spacers which can permit at least some remaining spinal flexibility.
BACKGROUND OF THE INVENTION Natural intervertebral spinal discs serve multiple purposes. The first, and perhaps most basic, is to preserve the anatomical spacing between adjacent vertebrae such that the spinal column and horizontally branching nerve bundles are allowed to function normally. A second major purpose is to allow relative flexural motion between adjacent vertebral bodies. Natural flexibility, at least of the upper spine, permits rotation about two horizontal axes and one vertical axis. Finally, the disc also serves as a shock absorber for columnar loading of the spine. However, mechanical trauma, degenerative disc disease, and other pathogenesis can compromise a disc's ability to maintain the spacing, facilitate flexibility, and provide the shock absorbing function.
One option after the surgical removal of a damaged disc might be to allow the intervertebral space to collapse. Collapse, however, usually causes compressive damage to the spinal cord and the associated nerve bundles. Also, the intervertebral space may fill with scar tissue that can aggravate nerve damage. Thus the simple removal of a damaged disc, without providing for maintenance of the normal vertebral spacing is undesirable. Discectomy therefore is usually supplemented by (1) rigid fusion of the adjacent vertebrae with new bone growth; (2) application of rigid nonfusing hardware; or (3) insertion of an artificial disc. As the patent literature shows, these approaches have been tried in many variations but have significant disadvantages. a. Vertebral Fusion
Well-known to those skilled in the art is interbody fusion wherein the disc is partially or wholly excised and living bone or various forms of calcium phosphate or other substrate material is placed within the space previously occupied by the disc for the purpose of restoring the normal separation, strength, and stability. Fusion is intended to provide healthy, living bone between the adjacent vertebrae.
For fusion to occur within the disc space, it is frequently necessary to prepare the adjacent vertebrae by excising portions of the cortical exterior surfaces, usually of the vertebral endplates so as to allow an interposed bone graft to come into direct contact with the cancellous (and vascularized) interior of the vertebrae.
Historically, two types of bone grafts have been available for anterior cervical fusion. One type is a round dowel plug-like configuration, such as the original Cloward dowel. The second type, a rectangular plug in a rectangular hole, is often referred to as the Smith-Robinson technique. The bone can be obtained from the patient's own iliac crest, from allograft cadaveric crest, or cut from a hard femoral cortical bone.
Both techniques can have disadvantages. For example, the dowel approach frequently flattens the intervertebral space, causing it to induce an undesirable kink in the natural lordosis. Also, the instrumentation used to implant the dowel is bulky and tends to be difficult to use. Thus many surgeons have abandoned this technique. The Smith-
Robinson approach has problems because lack of preparation of the endplates leads to non-incorporation and eventual collapse. Moreover, the use of autograft bone to fill the disc space is often less than optimal since it requires an additional incision and healing and is of limited availability in its most useful form. b. Artificial Discs
Extensive research has been devoted to developing an effective artificial disc. No such device has yet been found that is medically acceptable. Examples of various prosthetic or artificial disc attempts include Fassio, U.S. Pat. No. 2,372,622; Stubstad, U.S. Pat. No. 3,867,728; Froning, U.S. Pat. No. 3,875,595; Patil, U.S. Pat. No. 4,309,777; Kuntz, U.S. Pat. No. 4,349,921; Hirayama, et al., U.S. Pat. No. 4,946,378;
Nishijima, et al., U.S. Pat. No. 5,899,941; Bryan, et al., U.S. Pat. No. 6,001,130. Substantial numbers of others exist. c. Spacers
A number of intervertebral spacers designed for installation between adjacent vertebrae have been patented. These include: U.S. Pat. No. 6,086,613 to CAMINO, et al, relates to intervertebral spacers used in connection with spinal fusion. U.S. Pat. No. 6,039,762 to McKay describes a spacer body having an outer surface and a height approximating the height of a human disc space, said body composed of a porous, biocompatible ceramic material for permitting tissue ingrowth therethrough. U.S. Pat. No. 5,989,291 to RALPH, et al. describes an intervertebral spacer having a pair of opposing plates for seating against opposing vertebral bone surfaces, separated by at least one spring mechanism. In a first embodiment there are two Belleville washers which are oriented in opposite directions such that the narrow ends thereof are in contact with each other and the wider ends are in contact with the respective end plates. The Belleville washers work as springs. (Belleville washers are described as frustoconical in shape.)
U.S. Pat. No. 5,984,922 to McKay describes a spinal fixation device consisting of an intervertebral body wedge which is inserted between vertebral bodies by sequentially expanding the disc space using a spacer. No posterior fixation devices are needed for stabilization of the vertebrae. U.S. Pat. No. 5,888,222 to COATES, et al. describes a spinal spacer that engages adjacent vertebrae. The spacer includes a body having two ends, at least one of which "defines" an inferior vertebral engaging surface having a set of migration resistance grooves. U.S. Pat. No. 5,534,029 to Shia discloses an articulated vertebral body spacer consisting of a pair of upper and lower joint pieces to be inserted between vertebrae. This spacer allows its components to pivot in accordance with forward/backward and bending motions of vertebral bodies. U.S. Pat. No. 4,599,086 to Dogy discloses a spinal stabilization device positionable between separated but neighboring vertebrae. A wrench can be inserted into the opening until it engages a pair of pins, and then the wrench can be rotated to advance the pins into the abutting vertebral bodies.
Two spacer inventions that are designed specifically for use in connection with subsequent fusion processes are: U.S. Pat. No. 5,888,223 to BRAY, Jr., which discloses an anterior fixation device consisting of an oval shaped hollow intervertebral spacer and a retaining plate. The spacer has a side wall and superior and inferior walls. The superior and inferior walls are dome-shaped and porous to allow bone to grow through the device to achieve fusion of two adjacent vertebral bodies; and U.S. Pat. No. 5,865,848 to Baker describing a spinal fusion implant assembly for spacing vertebrae. The device includes a translation mechanism for providing relative motion between the components. An additional area of prior art includes all devices designed to be applied to one or more exterior surfaces of the spine. Such devices include all types of plates, struts, and rods which are attached by hooks, wires and screws. Other devices are simply variations on the use of rods (e.g. Harrington, Luque, Cotrel-Dubosset, Zielke), wires or cables (Dwyer), plates and screws (Steffee), or struts (Dunn, Knowles). A preferable spacer would at least to some extent preserve the ability of the patient to rotate portions of the spinal column about two perpendicular horizontal axes (and linear combinations thereof) and about the vertical axis. All of the prior art approaches suffer from the drawback that they either do not attempt to preserve such flexibility or they are unable in practice to achieve a workable device. In addition they suffer from other drawbacks.
The principal drawbacks of the fusion approach are that until very recently the success rate, that is, actual achievement of fusion, has been very modest. Secondly, in cervical as opposed to lumbar application, the diminution in mobility of the spine about rotational axes is a much more significant lasting effect for the patient. The principal aim of artificial discs has been to provide a prosthesis which ' preserves as much of the patient's prior ability to move as possible. The principal drawback of artificial discs is that they simply do not work in a medical sense.
Spacers have the drawback that, by themselves, they do not achieve the beneficial results of fusion. On the other hand, most of them are rigid, and therefore also have the same drawback as successful fusion, namely reducing the patient's flexibility.
OBJECTS OF THE INVENTION
Accordingly, it is an object of the present invention to provide a single- piece intervertebral implant that can serve as a spacer between adjacent cervical vertebrae. Another object of the invention is to provide an intervertebral implant that allows relative motion of the adjacent vertebral bodies. Another object of the present invention is to provide a low cost intervertebral implant that is small enough to allow rapid and easy anterior or posterior installation into either the cervical or the lumbar regions of the spine. Another object of the present invention is to provide an intervertebral implant device that is self-adhering upon installation. Another object of the present invention is to provide an intervertebral implant device that can maintain intimate, grasping adherence with the vertebral bodies, even when loaded in tension. Another object of the present invention is to provide an artificial disc prosthesis able to allow for full bending movement of the two vertebral bodies between which it is installed, allowing flexibility within both the lateral and sagittal planes.. Yet another object of the present invention is to provide an intervertebral implant device that can pierce the bony cortex of the vertebral bodied during installation. And yet a further object of the present invention is to provide an intervertebral implant device that provides self-centering alignment upon installation. Additional objects of the invention are to provide a single-piece spacer device which alone, or with a second such spacer device, can serve as a spacer between adjacent vertebra within the lumbar region of the spine as part of a vertebral fusion process. Yet another object of the present invention is to provide an intervertebral implant device that provides the correct amount of loading in order to promote bone growth and vertebral fusion. A final object of the invention is to provide a single-piece device which alone in the cervical region of the spine or in combination with a second like device in the lumbar region of the spine can be driven into an intervertebral space with a single force- applying operation for each of the one or two devices.
SUMMARY OF THE INVENTION
The present invention is an implantable intervertebral spacer designed to both preserve the space between adjacent vertebrae and to provide some continued spinal flexibility by virtue of its flexible construction. This spacer is also characterized by single piece construction and by the property of being self guiding upon initial insertion into the intervertebral space. This invention also has four spaced-apart tail pieces flexibly linked to one another, consisting of one upper set of two horizontally spaced-apart tail pieces and one lower set of two horizontally spaced-apart tail pieces, the upper and lower sets also being vertically spaced-apart from one another. Each of the two upper spaced-apart elongated tail pieces is independently flexibly linked to each of the corresponding spaced apart elongated lower tail pieces. Each of the tail pieces also comprises an elongated post supporting a bone gripping barb and a cutting edge having an inwardly angled facet. Upon installation between adjacent vertebral bodies, the implant is self locking by virtue of strain induced in the elongated barb-supporting posts. The device is implantable as a single unit within the intervertebral space between adjacent cervical vertebrae or it is implantable in conjunction with a second spacer within the same intervertebral space.
Because of the cutting edges and barbs, it is implanted by being impacted with a driver device, at which point it is firmly seated and will not pull or creep out. The device also has a wedge shaped front portion to guide it into the desired position during installation. The bone gripping induced strain manifests within each of the elongated posts supporting each barb of each spaced-apart pair of barbs when the facet causes inward bending strain of the elongated posts upon installation into the vertebral bone.
The present invention is an implantable intervertebral device that can be configured also to promote bone growth and vertebral fusion. The vertical slot between the upper and lower sets of the two horizontally spaced-apart tail pieces can be loaded with bone graft material and/or bone morphogenic protein so as to create a fusion column and promote intervertebral fusion. It is known that compressive loading of graft material promotes new bone growth and healing. (This principle is generally referred to as Wolffs law.) The horizontal slot between the upper and lower sets of tail pieces can be varied in height, and the radius of the internal void in the portion connecting the upper part of the device to the lower part of the device can be varied, both so as to provide flexing sufficient to produce enough loading on the graft material to promote bone growth and vertebral fusion while still providing sufficient compressive strength to maintain the necessary intervertebral spacing.
The spacer of the current invention can be fabricated from metal, preferably titanium or stainless steel. Or it can be fabricated from organic polymer such as thermoplastic or thermosetting plastic unfilled or filled with fibers such as glass, metal or carbon. Preferably, said implant spacer, if fabricated from organic polymer, is to be fabricated from polyether ether ketone (PEEK), most preferably filled with fibers of metal or glass or, most preferably, carbon. A second embodiment of the said cervicalMumbar implant spacer employs the use of bullets situated upon elongated posts instead of barbs as a way to grip the vertebral bone. The forward cutting edge of each bullet has an angled facet that causes induced strain to arise within the elongated support post during installation.
BRIEF DESCRIPTION OF THE DRAWINGS
FIGURE 1 is an oblique view of the cervical/lumbar implant spacer; FIGURE 2 A is a lateral orthogonal view of a single cervical/lumbar spacer inserted between two vertebrae;
FIGURE 2B is a sagittal orthogonal view of a single cervical/lumbar spacer inserted between two vertebrae;
FIGURE 3 A is a top view of the cervical/lumbar spacer; FIGURE 3B is a rear view of the cervical/lumbar spacer;
FIGURE 3C is a side view of the cervical/lumbar spacer;
FIGURE 4 is an oblique view of one embodiment of the cervical/lumbar implant spacer; and
FIGURE 5 is an oblique view of a second embodiment of the cervical/lumbar implant spacer.
IDENTIFICATION OF ITEMS IN THE FIGURES FIGURE 1 la ~ upper portion lb ~ lower portion
2 — dynamic cervical/lumbar spacer
3 ~ vertical slot
4 ~ body of spacer 5a,5b,5c,5d ~ elongated barb support posts (see 8)
6 ~ wedge shaped forward end of spacer 7a,7b,7c,7d ~ tail pieces of spacer
8 ~ bone gripping latching portion of spacer (see 5x)
9 — forward portion of the spacer 10 - sharp forward cutting edge of bone gripping latch portion
11 - medially inwardly angled facet
12 ~ rounded top side 14 — elongated bone engaging barb 16 — horizontal slot between tail pieces 18 ~ stress relieving region
FIGURE 2A
2 ~ dynamic cervical/lumbar spacer 7a,7c ~ tail pieces of spacer
8 ~ bone gripping latching portion of spacer
9 ~ forward portion of the spacer 11 — medially inwardly angled facet
14 — elongated bone engaging barb
16 — horizontal slot between tail pieces
17 — intervertebral space
18 ~ stress relieving region 20a — anterior side of vertebral body
20b ~ anterior side of vertebral body
22 ~ motion indicating two headed arrow (vertebral)
24a,24b — motion-indicating little arrows (spacer)
28 ~ flexural fulcrum region
FIGURE 2B
2 ~ dynamic cervical/lumbar spacer
7a,7b,7c,7d ~ tail pieces of spacer
8 ~ bone gripping latching portion of spacer 14 ~ elongated bone engaging barb
15 ~ stress relieving lateral flexure region 20a ~ anterior side of vertebral body 20b — anterior side of vertebral body
28 — flexural fulcrum region 30,32 ~ motion indicating arrows (vertebral)
34 ~ motion indicating two headed arrow (vertebral) 35a,35b ~ motion-indicating little arrows (spacer) 36a,36b ~ motion-indicating little arrows (spacer)
FIGURE 3A
2 ~ dynamic cervical/lumbar spacer 4 — body of spacer
5a, 5b, 5c, 5d - elongated barb support posts 6 — wedge shaped forward end of spacer 7b,7d ~ tail pieces of spacer 8 ~ bone gripping latching portion of spacer 9 — forward portion of the spacer
10 ~ sharp forward cutting edge of bone gripping latch portion
11 — medially inwardly angled facet
12 ~ rounded top side
14 — elongated bone engaging barb 16 — slot between tail pieces
18 — stress relieving region FIGURE 3B 2 ~ dynamic cervical/lumbar spacer
5a, 5b, 5c, 5d - elongated barb support posts
7a,7b,7c,7d — tail pieces of spacer
8 ~ bone gripping latching portion of spacer
12 ~ rounded top side
14 ~ elongated bone engaging barb 15 — stress relieving lateral flexure region
16 - horizontal slot between tail pieces
FIGURE 3C
2 ~ dynamic cervical/lumbar spacer 6 ~ wedge shaped forward end of spacer
7a,7b ~ tail pieces of spacer 8 ~ bone gripping latching portion of spacer 9 ~ forward portion of the spacer
10 — sharp forward cutting edge of bone gripping latch portion
11 — medially inwardly angled facet 14 ~ elongated bone engaging barb 15 — stress relieving lateral flexure region
FIGURE 4
40 ~ first embodiment of the dynamic lumbar/cervical spacer 42 — wedge shaped front portion 44a,44b,44c,44d ~ spaced apart elongated tail pieces
46 ~ strain relieving circular region
47 — slot separating upper and lower tail piece pairs. 48a,48b ~ upper and lower portions of spacer 40 50 ~ juncture slot separating the tail pieces 52a,52b,52c,52d — elongated support posts
54a,54b,54c,54d — elongated barbs 56 — facets 58 ~ sharp forward cutting edge
FIGURE 5
60 — second embodiment of the dynamic lumbar/cervical spacer
62 ~ wedge shaped front portion
64a,64b,64c,64d — spaced apart elongated tail pieces
66 — strain relieving circular region 67 ~ slot separating upper and lower tail piece pairs.
68a,68b ~ upper and lower portions of spacer 60
70 —juncture slot separating the tail pieces
72a,72b,72c,72d ~ elongated support posts
74a,74b,74c,74d ~ elongated bullets 76 ~ facets 78 ~ sharp forward cutting edge DESCRIPTION OF THE PREFERRED EMBODIMENTS
The present invention, known as the dynamic lumbar/cervical spacer, is an intervertebral implant device designed to perform one or a combination of three basic functions: (1) vertebral spacer; (2) spacer to be used in conjunction with vertebral fusion; and (3) artificial disc.
The said dynamic spacer is of single piece construction. It is self guiding upon initial insertion into the intervertebral space, and it is self locking upon installation between adjacent vertebral bodies. It is dynamic in the sense that it is designed to be flexible within both the sagittal and lateral planes; that is, subsequent to installation, the patient will be able to move in such a way that the vertebrae between which the spacer has been installed will be able to have some or all of the motions allowed by a natural and healthy intervertebral disc.
The dynamic spacer is provided with a pair of spaced apart cutting edges on the spacer's upper face and a similar pair of cutting edges on the spacer's lower face. The respective pairs of spaced apart cutting edges enable the spacer to cut into the adjacent vertebral bodies upon being driven into the intervertebral disc space. Each of the said cutting edges is furthermore provided with either "barbs" or "bullets" that inhibit subsequent movement or pullout of the spacer away from the vertebrae into which it has been driven. In addition, each pair of cutting edges is geometrically arranged upon an elongated post so as to provide a grasping force, through induced strain within the elongated posts so as to hold the spacer within intimate contact with each respective vertebra to which it is attached.
The dynamic vertebral spacer of the present invention is designed to be installable by being impacted or otherwise driven or forced into place with a driver device. The said spacer is also designed to be manufactured in a multiplicity of sizes and a multiplicity of proportions of length, width and height so as to accommodate a variety of intervertebral spacings and vertebral body sizes according to the needs of the patient.
The dynamic spacer is designed to also promote bone growth and intervertebral fusion. The vertical slot between the upper and lower sets of the two horizontally spaced-apart tail pieces can be configures so that it can be loaded with graft to create a fusion column and promote fusion. The horizontal slot between the upper and lower sets of tail pieces can be varied in height, and the radius of the inner void in the portion of the implant connecting the upper portions of the spacer to the lower portions of the spacer can also be varied, so as to provide enough flexing to produce loading on the graft sufficient to promote bone growth and vertebral fusion while also providing compressive strength sufficient to maintain the required separation of the adjacent vertebrae.
Referring now to FIGURE 1, there is shown in oblique view one embodiment of a single dynamic cervical/lumbar spacer 2 according to the present invention. The spacer 2 consists of a single piece body 4 having a wedge shaped front end 6 and four elongated tail pieces 7a, 7b, 7c and 7d flexibly attached to one another by way of the wedge shaped front end 6 located in the forward portion 9 of the spacer. Each of the elongated tail pieces 7a, 7b, 7c and 7d has contiguous with it a bone gripping latching portion 8 consisting of an elongated post 5a, 5b, 5c, 5d upon each of which is disposed a sharp forward cutting edge 10 having a medially inwardly angled facet 11, a rounded top side 12 and an elongated bone engaging barb 14. FIGURES 2A and 2B are orthogonal views of a single dynamic spacer according to the present invention inserted between the anterior portions of two vertebral bodies 20a, 20b. The bone grabbing latching portions 8 of the spacer 2 are shown embedded within the adjacent vertebral bodies 20a, 20b. The dynamic features of the dynamic spacer 2 will become evident upon examination of the following additional FIGURES.
FIGURES 3 A, 3B and 3C show three orthogonal views of the dynamic spacer 2 shown in FIGURE 1. FIGURE 3 A is a side view of the spacer 2 showing the single piece body 4 with the wedge shaped front end 6 and two of the four spaced apart and elongated tail pieces 7b, 7d separated from one another by the slot 16 and flexibly attached to one another by way of the wedge shaped front end 6. The slot 16 terminates in the stress relieving circular portion 18 near the front region 6 of the spacer. The bone gripping latching portions 8 are shown in FIGURE 3A being contiguous with the sharp forward cutting edge 10 and the medially inwardly angled facet 11 and the elongated bone engaging barb 14. More specifically, each bone latching portion 8 consists of an elongated support post 5a, 5b, 5c or 5d upon which is disposed the elongated bone engaging barb 14 having a forward cutting edge 10 with an angled facet 11.
Contemplation of the FIGURES 3 A, 3B and 3C will reveal to those skilled in the mechanical arts the dynamic aspect of the present vertebral spacer invention. In particular, in FIGURE 3B, the respective elongated tail pieces 7a,7b,7c,7d are able to move flexurally in relation to one another. For example, and referring to FIGURES 2A, 2B the spacer 2 is shown after having been inserted into the intervertebral space 17, by being forced in or driven in by impact. During the insertion process, the four medially inwardly directed facets 11 of the bone gripping portions 8 engage the cortex bone the vertebral bodies 20a, 20b in such as way as to force medially inwards, towards one another, the respective pairs of spaced apart elongated posts 5a, 5b and 5c, 5d such that induced strain in the elongated posts, as well as in the region 15 between the respective pairs of elongated tail pieces 7a,7c and 7b,7d, forces the elongated barbs 14 into intimate gripping contact with the vertebral bone.
During installation, flexure of the region 15 necessarily forces together the respective pairs of tail pieces 7a,7c and 7b,7d, but primarily induces gripping strain in the respective pairs of elongated posts 5a, 5c and 5b, 5d. As a result, the induced strain produces a laterally outwardly directed force that causes the elongated bone engaging barbs 14 to maintain in intimate contact with the vertebral bone. The inventor recognizes that the vertical portions of the bone gripping latching portions 8 also undergo a small degree of flexure and thereby also have an induced strain that serves to secure the spacer 2 in intimate contact with the vertebral bodies 20a, 20b. The dynamic aspects of the dynamic lumbar/cervical spacer are yet further evident within the context of FIGURES 2 A and 2B, which show the spacer 2 implanted between the two vertebrae 20a, 20b. FIGURE 2A shows the spacer 2 located more or less within the sagittal plane, with said the spacer being close to the anterior side of the vertebral bodies. Note the two-headed curved arrow 22, indicating relative motion of the two vertebral bodies, such motion being of the sort arising between vertebrae when the patient moves in such a way as corresponds to an arching of the back, i.e., bending backwards. Such increasing separation of the anterior sides of the respective vertebral bodies 20a, 20b can be accommodated by the dynamic spacer 2 in that the elongated tail pieces 7a,7c (and 7b,7d, not shown) can flex apart from one another about the fulcrum 28 within the circular stress-relieving region 18 located in the forward portion 9 of the spacer.
The flexure of the tail pieces 7a,7c is indicated by the small arrows 24,26. It is important to note that during spinal flexure of the sort causing increasing separation of the vertebral bodies 20a, 20b that the bone gripping latching portions 8 remain tightly in contact with the respective vertebral bodies, according to the design function of the elongated bone engaging barbs 14.
Correspondingly, when the patient's spine is flexed in the opposite direction, as during a forward bending motion, the space between the anterior sides of the vertebral bodies 20a, 20b shown in FIGURE 2A decreases. Under such conditions, the two-headed arrow 22 would be reversed so as to indicate a coming together of the vertebral bodies. Likewise, the tail pieces, 7a,7c would also be forced into closer proximity about the fulcrum 28, and the orientation of the small motion indicating arrows 24a,24b would be reversed from that shown in FIGURE 2 A. In FIGURE 2B, the fulcrum 28 can be seen to be a line (dotted) along the forwardmost side of the stress relieving region 18. (NOTE: In more specific point of fact, the line denoted by the callout number 28 in FIGURE 2B designates a zone of tension or compression as the whole forward region 9 of the spacer flexes in respective response to the increasing or decreasing separation of the upper tail pieces 7a,7b from the lower tail pieces 7c, 7d.)
Further details of the dynamic properties of the vertebral spacer 2 according to the present invention are illustrated in FIGURE 2B, which is a view of the implanted spacer from the anterior side of the spine, i.e., looking toward it from the front of the patient's body. The pair of curved arrows 30,32 and the single two-headed arrow 34 illustrate the relative motion of the two vertebral bodies 20a, 20b if the patient were to bend laterally (specifically toward the patient's left side). As viewed in FIGURE 2B, the right side of the vertebral bodies 20a, 20b become closer while the left side of the bodies move farther apart. The spacer 2 is able to accommodate such motion because the tail pieces 7b, 7d on the right side of the FIGURE can flex into closer proximity, due to compression, while the tail pieces 7a, 7c on the left side move farther apart, due to tension.
In both instances, compression or tension, the relative motions of the respective pairs of tail pieces 7a, 7c and 7b, 7d is associated with flexure about the fulcrum region 28 located within the stress relieving region 18 of the forward region 9 of the spacer.
Embodiment #1
FIGURE 4 shows in oblique view a first embodiment of the dynamic lumbar/cervical spacer 40 according to the present invention. The spacer 40 is of single- piece construction. It consists of a wedge shaped front portion 42 and an upper set of two spaced apart elongated tail pieces 44a, 44b and a lower set of two spaced apart elongated tail pieces 44c, 44d. Each of the upper pair of spaced apart tail pieces 44a, 44b are independently flexibly linked to each of the corresponding spaced apart lower tail pieces 44c, 44d respectively. The flexible link between the respective spaced apart upper tail pieces 44a, 44b and the corresponding lower tail pieces 44c, 44d is the front portion 42 containing a stress relieving circular region 46 at the forward end portion of the slot 47 separating the respective upper and lower pairs of tail pieces. The upper portion 48a and lower portion 48b of the spacer 40 are symmetrical with one another about the horizontal plane defined by the plane of the slot 47. Each of the two elongated upper tail pieces 44a,
44b is able to move in the vertical direction, independently of the other, in relation to each of the corresponding two lower tail pieces 44c, 44d, thereby affording movement between the vertebrae (20a, 20b in FIGURES 2A, 2B) in both the lateral and the sagittal planes. On the top of the upper portion 44a, disposed in a bilaterally symmetric way about the vertical plane defined by the juncture slot 50 separating the left tail pieces
44a, 44c from the right tail pieces 44b, 44d, are two elongated posts 52a, 52c. Each of the two elongated posts 52a, 52c is topped by an elongated barb 54a, 54c. Corresponding elongated barbs 54b, 54d are disposed on the lower portion 44b of the spacer 40. Facets 56 are disposed at the forward end of each elongated post and barb set, providing a sharp forward cutting edge 58 at the forward end of each of the four post and barb sets. Each of the four facets 56 (only two are shown in the FIGURE) is angled in such a way that when the spacer 40 is forced between the vertebral bodies (20a, 20b in FIGURES 2A, 2B), the upper set of elongated posts 52a, 52b and the lower sets of elongated posts 52c, 52d are forced medially toward one another in such a way that strain is induced in the respective elongated posts so as to facilitate the ability of the elongated barbs 54a, 54b, 54c, 54d to remain in continuing firm contact with the vertebral bone (not shown in FIGURE 4). As should be apparent to those skilled in the art, a portion of medially directed strain in each set of the elongated posts 52a, 52b and 52c, 52d is born by the respective tail pieces 44a through 44d.
Embodiment #2
FIGURE 5 shows in oblique view a second embodiment of the dynamic lumbar/cervical spacer 60 according to the present invention. The spacer 60 is of single- piece construction. It consists of a wedge shaped front portion 62 and an upper set of two spaced apart elongated tail pieces 64a, 64b and a lower set of two spaced apart elongated tail pieces 64c, 64d. Each of the upper pair of spaced apart tail pieces 64a, 64b are independently flexibly linked to each of the corresponding spaced apart lower tail pieces
64c, 64d respectively. The flexible link between the respective spaced apart upper tail pieces 64a, 64b and the corresponding lower tail pieces 64c, 64d is the front portion 62 containing a stress relieving circular region 66 at the forward end portion of the slot 67 separating the respective upper and lower pairs of tail pieces. The upper portion 68a and lower portion 68b of the spacer 60 are symmetrical with one another about the horizontal plane defined by the plane of the slot 67. Each of the two elongated upper tail pieces 64a, 64b is able to move in the vertical direction, independently of the other, in relation to each of the corresponding two lower tail pieces 64c, 64d, thereby affording movement between the vertebrae (20a, 20b in FIGURES 2A, 2B) in both the lateral and the sagittal planes. On the top of the upper portion 68a, disposed in a bilaterally symmetric way about the vertical plane defined by the juncture slot 70 separating the left tail pieces 64a, 64c from the right tail pieces 64b, 64d, are two elongated posts 72a, 72c. Each of the two elongated posts 72a, 72c is topped by an elongated bullet 74a, 74c. Corresponding elongated bullets 74b, 74d are disposed on the lower portion 68b of the spacer 60. Facets 76 are disposed at the forward end of each elongated post and bullet set, providing a sharp forward cutting edge 78 at the forward end of each of the four post and bullet sets. Each of the four facets 76 (only two are shown in the FIGURE) is angled in such a way that when the spacer 60 is forced between the vertebral bodies (20a, 20b in FIGURES 2A, 2B), the upper set of elongated posts 72a, 72b and the lower sets of elongated posts 72c, 72d are forced medially toward one another in such a way that strain is induced in the respective elongated posts so as to facilitate the ability of the elongated bullets 74a, 74b, 74c, 74d to remain in continuing firm contact with the vertebral bone (not shown in FIGURE 5). As should be apparent to those skilled in the art, a portion of medially directed strain in each set of the elongated posts 72a, 72b and 72c, 72d is born by the respective tail pieces 64a through 64d.
It will now be apparent to those skilled in the art that other embodiments, improvements, details and uses can be made consistent with the letter and spirit of the foregoing disclosure and within the scope of this patent, which is limited only by the following claims, construed in accordance with the patent law, including the doctrine of equivalents.

Claims

CLAIMSI claim:
1. An implantable dynamic intervertebral spacer configured to be flexible in both the saggital and lateral planes.
2. The spacer of Claim 1 wherein the spacer is of single piece construction.
3. The spacer of Claim 2 further having a body comprising a plurality of upper tail pieces and a plurality of lower tail pieces.
4. The spacer of Claim 3 in which the plurality of upper tail pieces comprises exactly two elongated tail pieces, the plurality of lower tail pieces comprises exactly two elongated tail pieces.
5. The spacer of Claim 4 in which the tail pieces are of equal length.
6. The spacer of Claim 4 in which the two upper tail pieces are vertically spaced apart from the two lower tail pieces, the two upper tail pieces being also horizontally spaced apart from each other by a specified distance, the lower tail pieces further being horizontally spaced apart from each other by a distance equal to the spacing apart distance of the upper tail pieces.
7. The spacer of Claim 3 in which each of the plural upper tail pieces and each of the plural lower tail pieces additionally comprises a barb support post.
8. The spacer of Claim 7 in which each of the barb support posts additionally comprises attached thereto an elongated bone engaging barb.
9. The spacer of Claim 4 in which each of the exactly two upper elongated tail pieces and each of the exactly two lower elongated tail pieces additionally comprises a barb support post.
10. The spacer of Claim 9 in which each of the barb support posts additionally comprises attached thereto an elongated bone engaging barb.
11. The spacer of Claim 8 in which each of the barb support posts additionally comprising an elongated bone engaging barb further additionally comprises a medially inwardly angled facet.
12. The spacer of Claim 10 in which each of the barb support posts additionally comprising an elongated bone engaging barb further additionally comprises a medially inwardly angled facet.
13. The spacer of Claim 11 in which each of the barb support posts additionally comprising an elongated bone engaging barb further comprises a bone gripping latching portion.
14. The spacer of Claim 12 in which each of the barb support posts additionally comprising an elongated bone engaging barb further comprises a bone gripping latching portion.
15. The spacer of Claim 7 in which each of the barb support posts additionally comprises attached thereto an elongated bullet configured to engage bone.
16. The spacer of Claim 9 in which each of the barb support posts additionally comprises attached thereto an elongated bullet configured to engage bone.
17. The spacer of Claim 15 in which each of the barb support posts additionally comprising an elongated bullet configured to engage bone further additionally comprises a medially inwardly angled facet.
18. The spacer of Claim 10 in which each of the barb support posts additionally comprising an elongated bullet configured to engage bone further additionally comprises a medially inwardly angled facet.
19. The spacer of Claim 2 in which the spacer is configured to be self guiding during installation.
20. The spacer of Claim 19 in which the self guiding configuration comprises a generally wedge shaped configuration on the distal portion of the spacer.
21. The spacer of Claim 4 in which the portion of the body connecting the upper tail pieces and the lower tail pieces provides independently flexible linkage between each of the upper tail pieces and the corresponding lower tail pieces.
22. The spacer of Claim 6 in which the two upper tail pieces and the two lower tail pieces are configured to provide a space capable of receiving bone graft and bone growth material.
23. The spacer of Claim 22 in which the two upper tail pieces and the two lower tail pieces are vertically spaced apart by a distance selected to provide sufficient flexibility to the overall configuration to promote new bone growth in bone graft and bone growth material placed in the space capable of receiving such material.
24. The spacer of Claim 3 additionally comprising a connecting portion between the upper tail pieces and the lower tail pieces, said connecting portion being configured with an open inner portion with a radius, said radius being capable of being chosen to produce a desired flexibility of the spacer as a whole.
PCT/US2001/048004 2000-12-19 2001-12-12 Dynamic implanted intervertebral spacer WO2002049539A2 (en)

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AU2002229008A AU2002229008A1 (en) 2000-12-19 2001-12-12 Dynamic implanted intervertebral spacer
EP01990138A EP1343440B1 (en) 2000-12-19 2001-12-12 Dynamic implanted intervertebral spacer
DE60128391T DE60128391T2 (en) 2000-12-19 2001-12-12 DYNAMIC IMPLANT INTERMEDIATE SPARKLING

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US25663200P 2000-12-19 2000-12-19
US60/256,632 2000-12-19
US09/988,931 US6743257B2 (en) 2000-12-19 2001-11-21 Dynamic implanted intervertebral spacer
US09/988,931 2001-11-21

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2902639A1 (en) * 2006-06-26 2007-12-28 Arca Medica Gmbh Patient`s lumbo-sacral region stabilizing implant, has U-shaped clamps respectively anchored on upper edges of plates of sacral vertebra and provided on both sides of branch of central body that is made of elastic material

Families Citing this family (284)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050245937A1 (en) * 2004-04-28 2005-11-03 St. Francis Medical Technologies, Inc. System and method for insertion of an interspinous process implant that is rotatable in order to retain the implant relative to the spinous processes
US20080086212A1 (en) 1997-01-02 2008-04-10 St. Francis Medical Technologies, Inc. Spine distraction implant
US6068630A (en) 1997-01-02 2000-05-30 St. Francis Medical Technologies, Inc. Spine distraction implant
US7201751B2 (en) * 1997-01-02 2007-04-10 St. Francis Medical Technologies, Inc. Supplemental spine fixation device
US7959652B2 (en) 2005-04-18 2011-06-14 Kyphon Sarl Interspinous process implant having deployable wings and method of implantation
US20080039859A1 (en) 1997-01-02 2008-02-14 Zucherman James F Spine distraction implant and method
FR2767675B1 (en) * 1997-08-26 1999-12-03 Materiel Orthopedique En Abreg INTERSOMATIC IMPLANT AND ANCILLARY OF PREPARATION SUITABLE FOR ALLOWING ITS POSITION
BR9917397A (en) 1999-07-02 2002-03-05 Spine Solutions Inc Intervertebral Implant
FR2897259B1 (en) 2006-02-15 2008-05-09 Ldr Medical Soc Par Actions Si INTERSOMATIC TRANSFORAMINAL CAGE WITH INTERBREBAL FUSION GRAFT AND CAGE IMPLANTATION INSTRUMENT
MXPA02002672A (en) * 1999-09-14 2003-10-14 Spine Solutions Inc Instrument for inserting intervertebral implants.
US6740090B1 (en) 2000-02-16 2004-05-25 Trans1 Inc. Methods and apparatus for forming shaped axial bores through spinal vertebrae
US6899716B2 (en) * 2000-02-16 2005-05-31 Trans1, Inc. Method and apparatus for spinal augmentation
DK1578315T3 (en) 2000-02-16 2008-10-06 Trans1 Inc Device for vertebral column distribution and fusion
US7744599B2 (en) 2000-02-16 2010-06-29 Trans1 Inc. Articulating spinal implant
US6558390B2 (en) * 2000-02-16 2003-05-06 Axiamed, Inc. Methods and apparatus for performing therapeutic procedures in the spine
US7169183B2 (en) * 2000-03-14 2007-01-30 Warsaw Orthopedic, Inc. Vertebral implant for promoting arthrodesis of the spine
FR2808995B1 (en) 2000-05-18 2003-02-21 Aesculap Sa INTERSOMATIC CAGE WITH UNIFIED GRAFT
EP1294295A4 (en) 2000-06-30 2009-12-23 Stephen Ritland Polyaxial connection device and method
FR2827156B1 (en) * 2001-07-13 2003-11-14 Ldr Medical VERTEBRAL CAGE DEVICE WITH MODULAR FASTENING
US8021399B2 (en) 2005-07-19 2011-09-20 Stephen Ritland Rod extension for extending fusion construct
CA2460183C (en) 2001-09-28 2011-04-12 Stephen Ritland Connection rod for screw or hook polyaxial system and method of use
AR038680A1 (en) 2002-02-19 2005-01-26 Synthes Ag INTERVERTEBRAL IMPLANT
WO2003073908A2 (en) 2002-02-20 2003-09-12 Stephen Ritland Pedicle screw connector apparatus and method
FR2837094B1 (en) * 2002-03-15 2004-11-26 Fixano INTERVERTEBRAL IMPLANT
US6966910B2 (en) * 2002-04-05 2005-11-22 Stephen Ritland Dynamic fixation device and method of use
US20080027548A9 (en) 2002-04-12 2008-01-31 Ferree Bret A Spacerless artificial disc replacements
US8038713B2 (en) 2002-04-23 2011-10-18 Spinecore, Inc. Two-component artificial disc replacements
US6706068B2 (en) 2002-04-23 2004-03-16 Bret A. Ferree Artificial disc replacements with natural kinematics
EP2457529A1 (en) 2002-05-08 2012-05-30 Stephen Ritland Dynamic fixation device and method of use
US7001433B2 (en) * 2002-05-23 2006-02-21 Pioneer Laboratories, Inc. Artificial intervertebral disc device
US8388684B2 (en) 2002-05-23 2013-03-05 Pioneer Signal Technology, Inc. Artificial disc device
US7052497B2 (en) 2002-08-14 2006-05-30 Sdgi Holdings, Inc. Techniques for spinal surgery and attaching constructs to vertebral elements
BR0313502A (en) * 2002-08-15 2005-07-12 Justin K Coppes Intervertebral disc
WO2004016217A2 (en) 2002-08-15 2004-02-26 David Gerber Controlled artificial intervertebral disc implant
US7125425B2 (en) * 2002-10-21 2006-10-24 Sdgi Holdings, Inc. Systems and techniques for restoring and maintaining intervertebral anatomy
US7063725B2 (en) * 2002-10-21 2006-06-20 Sdgi Holdings, Inc. Systems and techniques for restoring and maintaining intervertebral anatomy
US20080021468A1 (en) 2002-10-29 2008-01-24 Zucherman James F Interspinous process implants and methods of use
US7931674B2 (en) 2005-03-21 2011-04-26 Kyphon Sarl Interspinous process implant having deployable wing and method of implantation
US8070778B2 (en) 2003-05-22 2011-12-06 Kyphon Sarl Interspinous process implant with slide-in distraction piece and method of implantation
US8048117B2 (en) 2003-05-22 2011-11-01 Kyphon Sarl Interspinous process implant and method of implantation
US7549999B2 (en) 2003-05-22 2009-06-23 Kyphon Sarl Interspinous process distraction implant and method of implantation
US8147548B2 (en) 2005-03-21 2012-04-03 Kyphon Sarl Interspinous process implant having a thread-shaped wing and method of implantation
US7204852B2 (en) 2002-12-13 2007-04-17 Spine Solutions, Inc. Intervertebral implant, insertion tool and method of inserting same
EP2457541A1 (en) 2003-02-06 2012-05-30 Synthes GmbH Implant between vertebrae
US20040158254A1 (en) * 2003-02-12 2004-08-12 Sdgi Holdings, Inc. Instrument and method for milling a path into bone
US7235101B2 (en) 2003-09-15 2007-06-26 Warsaw Orthopedic, Inc. Revisable prosthetic device
CA2516791C (en) * 2003-02-25 2011-12-13 Stephen Ritland Adjustable rod and connector device and method of use
US20040176853A1 (en) * 2003-03-05 2004-09-09 Sennett Andrew R. Apparatus and method for spinal fusion using posteriorly implanted devices
US6908484B2 (en) * 2003-03-06 2005-06-21 Spinecore, Inc. Cervical disc replacement
AU2004220634B2 (en) * 2003-03-06 2009-09-17 Spinecore, Inc. Instrumentation and methods for use in implanting a cervical disc replacement device
US7491204B2 (en) * 2003-04-28 2009-02-17 Spine Solutions, Inc. Instruments and method for preparing an intervertebral space for receiving an artificial disc implant
WO2004110247A2 (en) 2003-05-22 2004-12-23 Stephen Ritland Intermuscular guide for retractor insertion and method of use
US7803162B2 (en) * 2003-07-21 2010-09-28 Spine Solutions, Inc. Instruments and method for inserting an intervertebral implant
US7204853B2 (en) * 2003-08-05 2007-04-17 Flexuspine, Inc. Artificial functional spinal unit assemblies
US7753958B2 (en) 2003-08-05 2010-07-13 Gordon Charles R Expandable intervertebral implant
US7909869B2 (en) 2003-08-05 2011-03-22 Flexuspine, Inc. Artificial spinal unit assemblies
US7785351B2 (en) * 2003-08-05 2010-08-31 Flexuspine, Inc. Artificial functional spinal implant unit system and method for use
US20050055099A1 (en) * 2003-09-09 2005-03-10 Ku David N. Flexible spinal disc
US7938858B2 (en) * 2003-09-15 2011-05-10 Warsaw Orthopedic, Inc. Spinal implant system
FR2860428B1 (en) * 2003-10-02 2006-05-12 Fixano INTERVERTEBRAL IMPLANT
MXPA06004374A (en) * 2003-10-20 2006-07-06 Blackstone Medical Inc Vertebral body replacement apparatus and method.
US9445916B2 (en) * 2003-10-22 2016-09-20 Pioneer Surgical Technology, Inc. Joint arthroplasty devices having articulating members
JP2007516738A (en) 2003-10-23 2007-06-28 トランスワン インコーポレイティッド Tools and tool kits for minimal intrusion processing on the spine
EP1694228B1 (en) * 2003-10-23 2011-08-31 TRANS1, Inc. Spinal mobility preservation apparatus
FR2861285B1 (en) * 2003-10-24 2006-02-17 Cousin Biotech INTERLAMARY SUPPORT
US7481839B2 (en) * 2003-12-02 2009-01-27 Kyphon Sarl Bioresorbable interspinous process implant for use with intervertebral disk remediation or replacement implants and procedures
US20050171608A1 (en) * 2004-01-09 2005-08-04 Sdgi Holdings, Inc. Centrally articulating spinal device and method
US20050171610A1 (en) * 2004-01-09 2005-08-04 Sdgi Holdings, Inc. Mobile bearing spinal device and method
US7771479B2 (en) 2004-01-09 2010-08-10 Warsaw Orthopedic, Inc. Dual articulating spinal device and method
US7297146B2 (en) 2004-01-30 2007-11-20 Warsaw Orthopedic, Inc. Orthopedic distraction implants and techniques
AU2005225208B2 (en) * 2004-03-26 2009-11-19 Nuvasive, Inc. Porous implant for spinal disc nucleus replacement
ATE506919T1 (en) * 2004-03-26 2011-05-15 Nuvasive Inc DISC PROSTHESIS
US20050222683A1 (en) * 2004-03-31 2005-10-06 Sdgi Holdings Shape memory alloy disc replacement device
WO2005112833A1 (en) * 2004-05-20 2005-12-01 Pearsalls Limited Improvements in and relating to surgical implants
US8388667B2 (en) * 2004-08-09 2013-03-05 Si-Bone, Inc. Systems and methods for the fixation or fusion of bone using compressive implants
US8470004B2 (en) 2004-08-09 2013-06-25 Si-Bone Inc. Apparatus, systems, and methods for stabilizing a spondylolisthesis
US7854752B2 (en) 2004-08-09 2010-12-21 Theken Spine, Llc System and method for dynamic skeletal stabilization
US9949843B2 (en) 2004-08-09 2018-04-24 Si-Bone Inc. Apparatus, systems, and methods for the fixation or fusion of bone
US8414648B2 (en) 2004-08-09 2013-04-09 Si-Bone Inc. Apparatus, systems, and methods for achieving trans-iliac lumbar fusion
US20060036251A1 (en) 2004-08-09 2006-02-16 Reiley Mark A Systems and methods for the fixation or fusion of bone
US8425570B2 (en) 2004-08-09 2013-04-23 Si-Bone Inc. Apparatus, systems, and methods for achieving anterior lumbar interbody fusion
US20180228621A1 (en) 2004-08-09 2018-08-16 Mark A. Reiley Apparatus, systems, and methods for the fixation or fusion of bone
WO2006020530A2 (en) * 2004-08-09 2006-02-23 Innovative Spinal Technologies System and method for dynamic skeletal stabilization
US8444693B2 (en) 2004-08-09 2013-05-21 Si-Bone Inc. Apparatus, systems, and methods for achieving lumbar facet fusion
US9662158B2 (en) 2004-08-09 2017-05-30 Si-Bone Inc. Systems and methods for the fixation or fusion of bone at or near a sacroiliac joint
US20070156241A1 (en) 2004-08-09 2007-07-05 Reiley Mark A Systems and methods for the fixation or fusion of bone
US20080097486A1 (en) * 2004-10-06 2008-04-24 Ross Anthony C Systems and Methods for Direct Restoration of Foraminal Volume
ATE524121T1 (en) 2004-11-24 2011-09-15 Abdou Samy DEVICES FOR PLACING AN ORTHOPEDIC INTERVERTEBRAL IMPLANT
US8038698B2 (en) 2005-02-17 2011-10-18 Kphon Sarl Percutaneous spinal implants and methods
US8097018B2 (en) 2005-02-17 2012-01-17 Kyphon Sarl Percutaneous spinal implants and methods
US8029567B2 (en) 2005-02-17 2011-10-04 Kyphon Sarl Percutaneous spinal implants and methods
US8157841B2 (en) 2005-02-17 2012-04-17 Kyphon Sarl Percutaneous spinal implants and methods
US7998174B2 (en) * 2005-02-17 2011-08-16 Kyphon Sarl Percutaneous spinal implants and methods
US8057513B2 (en) 2005-02-17 2011-11-15 Kyphon Sarl Percutaneous spinal implants and methods
US7988709B2 (en) 2005-02-17 2011-08-02 Kyphon Sarl Percutaneous spinal implants and methods
US20070276493A1 (en) 2005-02-17 2007-11-29 Malandain Hugues F Percutaneous spinal implants and methods
US8096994B2 (en) 2005-02-17 2012-01-17 Kyphon Sarl Percutaneous spinal implants and methods
US8100943B2 (en) * 2005-02-17 2012-01-24 Kyphon Sarl Percutaneous spinal implants and methods
US8007521B2 (en) 2005-02-17 2011-08-30 Kyphon Sarl Percutaneous spinal implants and methods
US8034080B2 (en) 2005-02-17 2011-10-11 Kyphon Sarl Percutaneous spinal implants and methods
US20060217731A1 (en) * 2005-03-28 2006-09-28 Sdgi Holdings, Inc. X-ray and fluoroscopic visualization slots
US8034079B2 (en) 2005-04-12 2011-10-11 Warsaw Orthopedic, Inc. Implants and methods for posterior dynamic stabilization of a spinal motion segment
US7727233B2 (en) 2005-04-29 2010-06-01 Warsaw Orthopedic, Inc. Spinous process stabilization devices and methods
US7799083B2 (en) * 2005-05-02 2010-09-21 Seaspine, Inc. Prosthesis for restoring motion in an appendage or spinal joint and an intervertebral spacer
WO2006119092A2 (en) * 2005-05-02 2006-11-09 Seaspine, Inc. Motion restoring intervertebral device
GB0514891D0 (en) * 2005-07-20 2005-08-24 Pearsalls Ltd Improvements in and relating to implants
US20090105826A1 (en) * 2005-06-03 2009-04-23 Mcleod Alan Surgical Implants
FR2887434B1 (en) 2005-06-28 2008-03-28 Jean Taylor SURGICAL TREATMENT EQUIPMENT OF TWO VERTEBRATES
EP1919403A2 (en) * 2005-07-06 2008-05-14 Copf jun., Franz Cage for the introduction into an intervertebral-disc compartment
FR2891135B1 (en) 2005-09-23 2008-09-12 Ldr Medical Sarl INTERVERTEBRAL DISC PROSTHESIS
US8267970B2 (en) * 2005-10-25 2012-09-18 Depuy Spine, Inc. Laminar hook spring
CA2632322C (en) * 2005-12-08 2014-04-08 Fbcdevice Aps Disc implant
US8002802B2 (en) * 2005-12-19 2011-08-23 Samy Abdou Devices and methods for inter-vertebral orthopedic device placement
US7922745B2 (en) * 2006-01-09 2011-04-12 Zimmer Spine, Inc. Posterior dynamic stabilization of the spine
US8083795B2 (en) 2006-01-18 2011-12-27 Warsaw Orthopedic, Inc. Intervertebral prosthetic device for spinal stabilization and method of manufacturing same
US7682376B2 (en) 2006-01-27 2010-03-23 Warsaw Orthopedic, Inc. Interspinous devices and methods of use
US7578849B2 (en) * 2006-01-27 2009-08-25 Warsaw Orthopedic, Inc. Intervertebral implants and methods of use
US7815663B2 (en) 2006-01-27 2010-10-19 Warsaw Orthopedic, Inc. Vertebral rods and methods of use
US7811326B2 (en) 2006-01-30 2010-10-12 Warsaw Orthopedic Inc. Posterior joint replacement device
US7635389B2 (en) * 2006-01-30 2009-12-22 Warsaw Orthopedic, Inc. Posterior joint replacement device
EP1988855A2 (en) * 2006-02-27 2008-11-12 Synthes GmbH Intervertebral implant with fixation geometry
US20070213826A1 (en) * 2006-03-08 2007-09-13 Seaspine, Inc. Intervertebral spacer and insertion tool providing multiple angles of insertion
US8118869B2 (en) 2006-03-08 2012-02-21 Flexuspine, Inc. Dynamic interbody device
US8409290B2 (en) 2006-03-08 2013-04-02 Seaspine, Inc. Interbody device for spinal applications
US8262698B2 (en) 2006-03-16 2012-09-11 Warsaw Orthopedic, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US8025681B2 (en) 2006-03-29 2011-09-27 Theken Spine, Llc Dynamic motion spinal stabilization system
US8118844B2 (en) 2006-04-24 2012-02-21 Warsaw Orthopedic, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US8048118B2 (en) 2006-04-28 2011-11-01 Warsaw Orthopedic, Inc. Adjustable interspinous process brace
US7959564B2 (en) 2006-07-08 2011-06-14 Stephen Ritland Pedicle seeker and retractor, and methods of use
US8048119B2 (en) 2006-07-20 2011-11-01 Warsaw Orthopedic, Inc. Apparatus for insertion between anatomical structures and a procedure utilizing same
US8998990B2 (en) 2006-07-24 2015-04-07 DePuy Synthes Products, LLC Intervertebral implant with keel
BRPI0714955A2 (en) 2006-07-31 2013-07-23 Systhes Gmbh instrument system and method for preparing an intervertebral space to receive an implant, and milling guide for use with an instrument system
US20080086115A1 (en) 2006-09-07 2008-04-10 Warsaw Orthopedic, Inc. Intercostal spacer device and method for use in correcting a spinal deformity
US8715350B2 (en) 2006-09-15 2014-05-06 Pioneer Surgical Technology, Inc. Systems and methods for securing an implant in intervertebral space
DE102006046330A1 (en) * 2006-09-28 2008-04-03 Bayer Materialscience Ag Polycarbonates and copolycarbonates with improved metal adhesion
US20080082172A1 (en) * 2006-09-29 2008-04-03 Jackson Roger P Interspinous process spacer
US8066750B2 (en) 2006-10-06 2011-11-29 Warsaw Orthopedic, Inc Port structures for non-rigid bone plates
US8097019B2 (en) 2006-10-24 2012-01-17 Kyphon Sarl Systems and methods for in situ assembly of an interspinous process distraction implant
FR2908035B1 (en) 2006-11-08 2009-05-01 Jean Taylor INTEREPINE IMPLANT
US7879104B2 (en) 2006-11-15 2011-02-01 Warsaw Orthopedic, Inc. Spinal implant system
US7955392B2 (en) * 2006-12-14 2011-06-07 Warsaw Orthopedic, Inc. Interspinous process devices and methods
US20080177389A1 (en) * 2006-12-21 2008-07-24 Rob Gene Parrish Intervertebral disc spacer
US9039768B2 (en) 2006-12-22 2015-05-26 Medos International Sarl Composite vertebral spacers and instrument
US8029544B2 (en) 2007-01-02 2011-10-04 Zimmer Spine, Inc. Spine stiffening device
US8597358B2 (en) * 2007-01-19 2013-12-03 Flexuspine, Inc. Dynamic interbody devices
US7942104B2 (en) * 2007-01-22 2011-05-17 Nuvasive, Inc. 3-dimensional embroidery structures via tension shaping
US7946236B2 (en) * 2007-01-31 2011-05-24 Nuvasive, Inc. Using zigzags to create three-dimensional embroidered structures
US8034081B2 (en) 2007-02-06 2011-10-11 CollabComl, LLC Interspinous dynamic stabilization implant and method of implanting
WO2008098125A2 (en) * 2007-02-08 2008-08-14 Nuvasive, Inc. Medical implants with pre-settled cores and related methods
US9381047B2 (en) 2007-05-09 2016-07-05 Ebi, Llc Interspinous implant
US9173686B2 (en) * 2007-05-09 2015-11-03 Ebi, Llc Interspinous implant
US8864832B2 (en) * 2007-06-20 2014-10-21 Hh Spinal Llc Posterior total joint replacement
FR2916956B1 (en) 2007-06-08 2012-12-14 Ldr Medical INTERSOMATIC CAGE, INTERVERTEBRAL PROSTHESIS, ANCHORING DEVICE AND IMPLANTATION INSTRUMENTATION
US20100191333A1 (en) * 2007-06-08 2010-07-29 Morrison Iii Thomas J Load-bearing spinal interbody device
US10821003B2 (en) 2007-06-20 2020-11-03 3Spline Sezc Spinal osteotomy
US8282681B2 (en) * 2007-08-13 2012-10-09 Nuvasive, Inc. Bioresorbable spinal implant and related methods
US8968365B2 (en) * 2007-09-14 2015-03-03 DePuy Synthes Products, LLC Interspinous spacer
US8182514B2 (en) 2007-10-22 2012-05-22 Flexuspine, Inc. Dampener system for a posterior stabilization system with a fixed length elongated member
US8187330B2 (en) 2007-10-22 2012-05-29 Flexuspine, Inc. Dampener system for a posterior stabilization system with a variable length elongated member
US8267965B2 (en) 2007-10-22 2012-09-18 Flexuspine, Inc. Spinal stabilization systems with dynamic interbody devices
US8162994B2 (en) 2007-10-22 2012-04-24 Flexuspine, Inc. Posterior stabilization system with isolated, dual dampener systems
US8523912B2 (en) 2007-10-22 2013-09-03 Flexuspine, Inc. Posterior stabilization systems with shared, dual dampener systems
US8157844B2 (en) 2007-10-22 2012-04-17 Flexuspine, Inc. Dampener system for a posterior stabilization system with a variable length elongated member
EP2217179A1 (en) 2007-11-16 2010-08-18 Synthes GmbH Low profile intervertebral implant
WO2009092030A1 (en) * 2008-01-16 2009-07-23 Life Spine, Inc. Spinal inetrbody fusion cages providing variable anterior/posterior profieles
US20090198338A1 (en) * 2008-02-04 2009-08-06 Phan Christopher U Medical implants and methods
US8088163B1 (en) 2008-02-06 2012-01-03 Kleiner Jeffrey B Tools and methods for spinal fusion
US8083796B1 (en) * 2008-02-29 2011-12-27 Nuvasive, Inc. Implants and methods for spinal fusion
US8114136B2 (en) 2008-03-18 2012-02-14 Warsaw Orthopedic, Inc. Implants and methods for inter-spinous process dynamic stabilization of a spinal motion segment
US20090248092A1 (en) 2008-03-26 2009-10-01 Jonathan Bellas Posterior Intervertebral Disc Inserter and Expansion Techniques
US8377135B1 (en) 2008-03-31 2013-02-19 Nuvasive, Inc. Textile-based surgical implant and related methods
KR101547212B1 (en) * 2008-04-22 2015-08-25 키네틱 스파인 테크놀로지스 인크. Artificial intervertebral spacer
US20100004747A1 (en) * 2008-07-07 2010-01-07 Jin-Fu Lin Trans-Vertebral and Intra-Vertebral Plate and Fusion Cage Device for Spinal Interbody Fusion and Method of Operation
USD853560S1 (en) 2008-10-09 2019-07-09 Nuvasive, Inc. Spinal implant insertion device
JP5893407B2 (en) 2008-10-21 2016-03-23 ダブリュ・ダブリュ・テクノロジー・アクチェンゲゼルシャフトWw Technology Ag Fusion device and tool set for fusing human or animal joints
US8114131B2 (en) 2008-11-05 2012-02-14 Kyphon Sarl Extension limiting devices and methods of use for the spine
BRPI0921486A2 (en) 2008-11-07 2019-09-10 Synthes Gmbh vertebral intercorporeal unit of spacer and coupled plate
US8366748B2 (en) 2008-12-05 2013-02-05 Kleiner Jeffrey Apparatus and method of spinal implant and fusion
US9717403B2 (en) 2008-12-05 2017-08-01 Jeffrey B. Kleiner Method and apparatus for performing retro peritoneal dissection
US8864654B2 (en) 2010-04-20 2014-10-21 Jeffrey B. Kleiner Method and apparatus for performing retro peritoneal dissection
EP2376028B1 (en) * 2008-12-22 2017-02-22 Synthes GmbH Orthopedic implant with flexible keel
US8157865B2 (en) * 2009-01-22 2012-04-17 Stephen Hochschuler Apparatus and method for stabilizing adjacent bone portions
US10052139B2 (en) 2009-01-26 2018-08-21 Life Spine, Inc. Flexible and static interspinous/inter-laminar spinal spacers
US8236031B2 (en) * 2009-01-26 2012-08-07 Life Spine, Inc. Flexible and static interspinous/inter-laminar spinal spacers
US9247943B1 (en) 2009-02-06 2016-02-02 Kleiner Intellectual Property, Llc Devices and methods for preparing an intervertebral workspace
USD656610S1 (en) 2009-02-06 2012-03-27 Kleiner Jeffrey B Spinal distraction instrument
EP2408382A4 (en) 2009-03-13 2013-06-19 Univ Toledo Minimally invasive collapsible cage
US9526620B2 (en) 2009-03-30 2016-12-27 DePuy Synthes Products, Inc. Zero profile spinal fusion cage
US8372117B2 (en) 2009-06-05 2013-02-12 Kyphon Sarl Multi-level interspinous implants and methods of use
US8157842B2 (en) 2009-06-12 2012-04-17 Kyphon Sarl Interspinous implant and methods of use
ES2659063T3 (en) 2009-09-17 2018-03-13 Ldr Holding Corporation Intervertebral implant incorporating expandable bone fixation members
US8685031B2 (en) 2009-09-18 2014-04-01 Spinal Surgical Strategies, Llc Bone graft delivery system
US10973656B2 (en) 2009-09-18 2021-04-13 Spinal Surgical Strategies, Inc. Bone graft delivery system and method for using same
USD723682S1 (en) 2013-05-03 2015-03-03 Spinal Surgical Strategies, Llc Bone graft delivery tool
USD750249S1 (en) 2014-10-20 2016-02-23 Spinal Surgical Strategies, Llc Expandable fusion cage
US8906028B2 (en) 2009-09-18 2014-12-09 Spinal Surgical Strategies, Llc Bone graft delivery device and method of using the same
US10245159B1 (en) 2009-09-18 2019-04-02 Spinal Surgical Strategies, Llc Bone graft delivery system and method for using same
US9173694B2 (en) 2009-09-18 2015-11-03 Spinal Surgical Strategies, Llc Fusion cage with combined biological delivery system
US9629729B2 (en) 2009-09-18 2017-04-25 Spinal Surgical Strategies, Llc Biological delivery system with adaptable fusion cage interface
US9060877B2 (en) 2009-09-18 2015-06-23 Spinal Surgical Strategies, Llc Fusion cage with combined biological delivery system
US9186193B2 (en) 2009-09-18 2015-11-17 Spinal Surgical Strategies, Llc Fusion cage with combined biological delivery system
US20170238984A1 (en) 2009-09-18 2017-08-24 Spinal Surgical Strategies, Llc Bone graft delivery device with positioning handle
US8771317B2 (en) 2009-10-28 2014-07-08 Warsaw Orthopedic, Inc. Interspinous process implant and method of implantation
US8764806B2 (en) 2009-12-07 2014-07-01 Samy Abdou Devices and methods for minimally invasive spinal stabilization and instrumentation
US9393129B2 (en) 2009-12-10 2016-07-19 DePuy Synthes Products, Inc. Bellows-like expandable interbody fusion cage
CA3003975A1 (en) 2009-12-31 2011-07-07 Ldr Medical Anchoring device, intervertebral implant and implantation instrument
US8317831B2 (en) 2010-01-13 2012-11-27 Kyphon Sarl Interspinous process spacer diagnostic balloon catheter and methods of use
US8114132B2 (en) 2010-01-13 2012-02-14 Kyphon Sarl Dynamic interspinous process device
US8388656B2 (en) * 2010-02-04 2013-03-05 Ebi, Llc Interspinous spacer with deployable members and related method
EP2538889A1 (en) * 2010-02-22 2013-01-02 Synthes GmbH Total disc replacement with w-shaped spring elements
US8147526B2 (en) 2010-02-26 2012-04-03 Kyphon Sarl Interspinous process spacer diagnostic parallel balloon catheter and methods of use
US8814908B2 (en) 2010-07-26 2014-08-26 Warsaw Orthopedic, Inc. Injectable flexible interspinous process device system
US20120078373A1 (en) 2010-09-23 2012-03-29 Thomas Gamache Stand alone intervertebral fusion device
US11529241B2 (en) 2010-09-23 2022-12-20 DePuy Synthes Products, Inc. Fusion cage with in-line single piece fixation
US20120078372A1 (en) 2010-09-23 2012-03-29 Thomas Gamache Novel implant inserter having a laterally-extending dovetail engagement feature
KR101052833B1 (en) * 2010-10-28 2011-07-29 박경우 A intervertebral cage having flexibility
US8512408B2 (en) 2010-12-17 2013-08-20 Warsaw Orthopedic, Inc. Flexiable spinal implant
EP2654626B1 (en) 2010-12-21 2016-02-24 Synthes GmbH Intervertebral implants and systems
US8388687B2 (en) 2011-03-25 2013-03-05 Flexuspine, Inc. Interbody device insertion systems and methods
US8591548B2 (en) 2011-03-31 2013-11-26 Warsaw Orthopedic, Inc. Spinous process fusion plate assembly
US8591549B2 (en) 2011-04-08 2013-11-26 Warsaw Orthopedic, Inc. Variable durometer lumbar-sacral implant
WO2013025702A1 (en) 2011-08-16 2013-02-21 Osteospring Medical, Inc. Wedge shaped fracture fixation devices and methods for using the same
US9668783B2 (en) 2011-09-06 2017-06-06 Atul Goel Devices and method for treatment of spondylotic disease
US8845728B1 (en) 2011-09-23 2014-09-30 Samy Abdou Spinal fixation devices and methods of use
US9526627B2 (en) 2011-11-17 2016-12-27 Exactech, Inc. Expandable interbody device system and method
US9198769B2 (en) 2011-12-23 2015-12-01 Pioneer Surgical Technology, Inc. Bone anchor assembly, bone plate system, and method
WO2013123497A1 (en) * 2012-02-17 2013-08-22 The Unversity Of Toledo Hybrid multifunctional posterior interspinous fusion device
US20130226240A1 (en) 2012-02-22 2013-08-29 Samy Abdou Spinous process fixation devices and methods of use
FR2987256B1 (en) 2012-02-24 2014-08-08 Ldr Medical ANCHORING DEVICE FOR INTERVERTEBRAL IMPLANT, INTERVERTEBRAL IMPLANT AND IMPLANTATION INSTRUMENTATION
US9271836B2 (en) 2012-03-06 2016-03-01 DePuy Synthes Products, Inc. Nubbed plate
WO2013134682A1 (en) 2012-03-09 2013-09-12 Si-Bone Inc. Artificial si joint
IN2014DN06946A (en) 2012-03-09 2015-04-10 Si Bone Inc
US10363140B2 (en) 2012-03-09 2019-07-30 Si-Bone Inc. Systems, device, and methods for joint fusion
WO2013149134A2 (en) * 2012-03-30 2013-10-03 Olympus Biotech Corporation Alif spinal implant
ES2828357T3 (en) 2012-05-04 2021-05-26 Si Bone Inc Fenestrated implant
US9278008B2 (en) 2012-05-30 2016-03-08 Globus Medical, Inc. Expandable interbody spacer
US9044342B2 (en) 2012-05-30 2015-06-02 Globus Medical, Inc. Expandable interbody spacer
US9198767B2 (en) 2012-08-28 2015-12-01 Samy Abdou Devices and methods for spinal stabilization and instrumentation
US9320617B2 (en) 2012-10-22 2016-04-26 Cogent Spine, LLC Devices and methods for spinal stabilization and instrumentation
US10182921B2 (en) 2012-11-09 2019-01-22 DePuy Synthes Products, Inc. Interbody device with opening to allow packing graft and other biologics
US8945228B2 (en) 2012-11-15 2015-02-03 DePuy Synthes Products, LLC Endplate for a vertebral implant
US9492288B2 (en) 2013-02-20 2016-11-15 Flexuspine, Inc. Expandable fusion device for positioning between adjacent vertebral bodies
US20170319348A1 (en) * 2015-08-10 2017-11-09 Catalyst Orthoscience Inc. Arthroplasty prostheses with multi-axis fixation
US11007063B2 (en) 2013-03-11 2021-05-18 Catalyst Orthoscience Inc. Offset reamers
US10973646B2 (en) 2013-03-11 2021-04-13 Catalyst Orthoscience Inc. Stabilized drill guide
US9913728B2 (en) 2013-03-14 2018-03-13 Quandary Medical, Llc Spinal implants and implantation system
US9149366B2 (en) * 2013-03-14 2015-10-06 Warsaw Orthopedic, Inc. Adaptable interbody implant and methods of use
CA2906882A1 (en) 2013-03-15 2014-09-18 Revivo Medical, Llc Intervertebral cage and method of treating vertebrae with an intervertebral cage
US9936983B2 (en) 2013-03-15 2018-04-10 Si-Bone Inc. Implants for spinal fixation or fusion
US11147688B2 (en) 2013-10-15 2021-10-19 Si-Bone Inc. Implant placement
WO2015057866A1 (en) 2013-10-15 2015-04-23 Si-Bone Inc. Implant placement
EP3104793B1 (en) * 2014-02-14 2024-02-21 Spectrum Spine IP Holdings, LLC Cervical minimal access fusion system
US9757248B2 (en) 2014-04-08 2017-09-12 Degen Medical, Inc. Intervertebral spacers
US9517144B2 (en) 2014-04-24 2016-12-13 Exactech, Inc. Limited profile intervertebral implant with incorporated fastening mechanism
US10398565B2 (en) 2014-04-24 2019-09-03 Choice Spine, Llc Limited profile intervertebral implant with incorporated fastening and locking mechanism
WO2016044731A1 (en) 2014-09-18 2016-03-24 Si-Bone Inc. Implants for bone fixation or fusion
US9662157B2 (en) 2014-09-18 2017-05-30 Si-Bone Inc. Matrix implant
US10383733B2 (en) 2014-10-22 2019-08-20 Biomet C.V. Method and apparatus for bone fixation
US9867718B2 (en) 2014-10-22 2018-01-16 DePuy Synthes Products, Inc. Intervertebral implants, systems, and methods of use
FR3029770B1 (en) * 2014-12-12 2019-11-08 Hassan Razian INTERVERTEBRAL CAGE
CN104546230B (en) * 2015-01-19 2017-02-01 南京航空航天大学 Artificial cervical intervertebral disc based on bending section with reversed U-shaped structure having like-trapezoidal section
US10376206B2 (en) 2015-04-01 2019-08-13 Si-Bone Inc. Neuromonitoring systems and methods for bone fixation or fusion procedures
US10857003B1 (en) 2015-10-14 2020-12-08 Samy Abdou Devices and methods for vertebral stabilization
USD797290S1 (en) 2015-10-19 2017-09-12 Spinal Surgical Strategies, Llc Bone graft delivery tool
EP3393404A4 (en) 2015-12-21 2019-08-07 Southern Spine, LLC Expandable interbody devices and related instruments and methods for spinal fusion surgery
EP3484416A1 (en) * 2016-07-18 2019-05-22 Catalyst Orthoscience Inc. Arthroplasty prostheses with multi-axis fixation
US10537434B2 (en) * 2016-08-08 2020-01-21 Wu Jau Ching Intervertebral implant
US10258483B2 (en) 2016-08-19 2019-04-16 Degen Medical, Inc. Laminate implantable medical devices
US10744000B1 (en) 2016-10-25 2020-08-18 Samy Abdou Devices and methods for vertebral bone realignment
US10973648B1 (en) 2016-10-25 2021-04-13 Samy Abdou Devices and methods for vertebral bone realignment
US11553946B2 (en) 2017-04-24 2023-01-17 Southern Spine, Llc Convertible dynamic interspinous process devices and methods for spinal surgery
US10940016B2 (en) 2017-07-05 2021-03-09 Medos International Sarl Expandable intervertebral fusion cage
AU2018327353A1 (en) 2017-09-08 2020-03-19 Pioneer Surgical Technology, Inc. Intervertebral implants, instruments, and methods
US11801144B2 (en) 2017-09-14 2023-10-31 Degen Medical, Inc. Methods of making medical devices
EP3687422A4 (en) 2017-09-26 2021-09-22 SI-Bone, Inc. Systems and methods for decorticating the sacroiliac joint
USD907771S1 (en) 2017-10-09 2021-01-12 Pioneer Surgical Technology, Inc. Intervertebral implant
US11179248B2 (en) 2018-10-02 2021-11-23 Samy Abdou Devices and methods for spinal implantation
US11123198B2 (en) 2018-11-13 2021-09-21 Degen Medical, Inc. Expandable spacers
US11234829B2 (en) 2019-01-21 2022-02-01 Degen Medical, Inc. Expandable intervertebral spacers
AU2020223180A1 (en) 2019-02-14 2021-07-22 Si-Bone Inc. Implants for spinal fixation and or fusion
US11369419B2 (en) 2019-02-14 2022-06-28 Si-Bone Inc. Implants for spinal fixation and or fusion
US11547575B2 (en) 2019-09-27 2023-01-10 Degen Medical, Inc. Expandable intervertebral spacers
EP4065015A4 (en) 2019-11-27 2024-01-03 Si Bone Inc Bone stabilizing implants and methods of placement across si joints
EP4259015A1 (en) 2020-12-09 2023-10-18 SI-Bone, Inc. Sacro-iliac joint stabilizing implants and methods of implantation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059193A (en) * 1989-11-20 1991-10-22 Spine-Tech, Inc. Expandable spinal implant and surgical method
US5390683A (en) * 1991-02-22 1995-02-21 Pisharodi; Madhavan Spinal implantation methods utilizing a middle expandable implant
US6019793A (en) * 1996-10-21 2000-02-01 Synthes Surgical prosthetic device
US6129763A (en) * 1996-09-13 2000-10-10 Chauvin; Jean-Luc Expandable osteosynthesis cage

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA992255A (en) 1971-01-25 1976-07-06 Cutter Laboratories Prosthesis for spinal repair
US3875595A (en) 1974-04-15 1975-04-08 Edward C Froning Intervertebral disc prosthesis and instruments for locating same
CA1146301A (en) 1980-06-13 1983-05-17 J. David Kuntz Intervertebral disc prosthesis
US4309777A (en) 1980-11-13 1982-01-12 Patil Arun A Artificial intervertebral disc
US4599086A (en) 1985-06-07 1986-07-08 Doty James R Spine stabilization device and method
JPH01136655A (en) * 1987-11-24 1989-05-29 Asahi Optical Co Ltd Movable type pyramid spacer
US5320644A (en) * 1991-08-30 1994-06-14 Sulzer Brothers Limited Intervertebral disk prosthesis
SE510158C2 (en) * 1992-10-29 1999-04-26 Medevelop Ab Anchorage elements for supporting prostheses and the use of such anchorage elements for fixing dentures
JPH06178787A (en) 1992-12-14 1994-06-28 Shima Yumiko Centrum spacer with joint, intervertebral cavity measuring device and centrum spacer pattern
FR2707480B1 (en) * 1993-06-28 1995-10-20 Bisserie Michel Intervertebral disc prosthesis.
US5584831A (en) 1993-07-09 1996-12-17 September 28, Inc. Spinal fixation device and method
FR2709949B1 (en) * 1993-09-14 1995-10-13 Commissariat Energie Atomique Intervertebral disc prosthesis.
FR2715293B1 (en) * 1994-01-26 1996-03-22 Biomat Vertebral interbody fusion cage.
FR2722980B1 (en) * 1994-07-26 1996-09-27 Samani Jacques INTERTEPINOUS VERTEBRAL IMPLANT
EP0700671B1 (en) * 1994-09-08 2001-08-08 Stryker Technologies Corporation Hydrogel intervertebral disc nucleus
US5470230A (en) * 1994-09-30 1995-11-28 Daftary; Fereidoun Anatomical dental implant with expandable root
US5824093A (en) * 1994-10-17 1998-10-20 Raymedica, Inc. Prosthetic spinal disc nucleus
US5674296A (en) 1994-11-14 1997-10-07 Spinal Dynamics Corporation Human spinal disc prosthesis
FR2728159B1 (en) * 1994-12-16 1997-06-27 Tornier Sa ELASTIC DISC PROSTHESIS
US6039762A (en) 1995-06-07 2000-03-21 Sdgi Holdings, Inc. Reinforced bone graft substitutes
US5782865A (en) * 1995-08-25 1998-07-21 Grotz; Robert Thomas Stabilizer for human joints
US5888222A (en) 1995-10-16 1999-03-30 Sdgi Holding, Inc. Intervertebral spacers
AU705598B2 (en) 1995-12-08 1999-05-27 Robert S. Bray Jr. Anterior stabilization device
US5749916A (en) * 1997-01-21 1998-05-12 Spinal Innovations Fusion implant
US5865848A (en) 1997-09-12 1999-02-02 Artifex, Ltd. Dynamic intervertebral spacer and method of use
US5899941A (en) 1997-12-09 1999-05-04 Chubu Bearing Kabushiki Kaisha Artificial intervertebral disk
US6086613A (en) 1997-12-23 2000-07-11 Depuy Acromed, Inc. Spacer assembly for use in spinal surgeries
US5989291A (en) 1998-02-26 1999-11-23 Third Millennium Engineering, Llc Intervertebral spacer device
US6132465A (en) * 1998-06-04 2000-10-17 Raymedica, Inc. Tapered prosthetic spinal disc nucleus
US6126689A (en) * 1998-06-15 2000-10-03 Expanding Concepts, L.L.C. Collapsible and expandable interbody fusion device
JP4230666B2 (en) * 1998-10-20 2009-02-25 ジンテーズ ゲゼルシャフト ミト ベシュレンクテル ハフツング Strain adjustment fixture for vertebral fixation surgery
US6193757B1 (en) * 1998-10-29 2001-02-27 Sdgi Holdings, Inc. Expandable intervertebral spacers
US6461359B1 (en) * 1999-11-10 2002-10-08 Clifford Tribus Spine stabilization device
EP1576938B1 (en) * 2000-10-11 2006-08-02 Michael D. Mason Spinal fusion device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059193A (en) * 1989-11-20 1991-10-22 Spine-Tech, Inc. Expandable spinal implant and surgical method
US5390683A (en) * 1991-02-22 1995-02-21 Pisharodi; Madhavan Spinal implantation methods utilizing a middle expandable implant
US6129763A (en) * 1996-09-13 2000-10-10 Chauvin; Jean-Luc Expandable osteosynthesis cage
US6019793A (en) * 1996-10-21 2000-02-01 Synthes Surgical prosthetic device

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1343440A2 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2902639A1 (en) * 2006-06-26 2007-12-28 Arca Medica Gmbh Patient`s lumbo-sacral region stabilizing implant, has U-shaped clamps respectively anchored on upper edges of plates of sacral vertebra and provided on both sides of branch of central body that is made of elastic material
EP1872731A1 (en) * 2006-06-26 2008-01-02 ARCA-MEDICA GmbH Implant intended for stabilising the lumbo-sacral region

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Publication number Publication date
EP1343440B1 (en) 2007-05-09
DE60128391D1 (en) 2007-06-21
US6743257B2 (en) 2004-06-01
EP1343440A4 (en) 2005-02-23
ATE361722T1 (en) 2007-06-15
EP1343440A2 (en) 2003-09-17
AU2002229008A1 (en) 2002-07-01
WO2002049539A3 (en) 2003-02-27
US20020077702A1 (en) 2002-06-20
DE60128391T2 (en) 2008-01-10

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