WO2002056049A3 - Microfluidic device with multiple microcoil nmr detectors - Google Patents

Microfluidic device with multiple microcoil nmr detectors Download PDF

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Publication number
WO2002056049A3
WO2002056049A3 PCT/US2001/046733 US0146733W WO02056049A3 WO 2002056049 A3 WO2002056049 A3 WO 2002056049A3 US 0146733 W US0146733 W US 0146733W WO 02056049 A3 WO02056049 A3 WO 02056049A3
Authority
WO
WIPO (PCT)
Prior art keywords
nmr
microfluidic device
detection sites
nmr detectors
microcoil nmr
Prior art date
Application number
PCT/US2001/046733
Other languages
French (fr)
Other versions
WO2002056049A2 (en
Inventor
Tim Peck
Dean Olson
Jim Norcross
David Strand
Jonathan Sweedler
Original Assignee
Protasis Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protasis Corporation filed Critical Protasis Corporation
Priority to AU2002241595A priority Critical patent/AU2002241595A1/en
Priority to EP01988273A priority patent/EP1340094A2/en
Publication of WO2002056049A2 publication Critical patent/WO2002056049A2/en
Publication of WO2002056049A3 publication Critical patent/WO2002056049A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/30—Sample handling arrangements, e.g. sample cells, spinning mechanisms
    • G01R33/302—Miniaturized sample handling arrangements for sampling small quantities, e.g. flow-through microfluidic NMR chips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/30—Sample handling arrangements, e.g. sample cells, spinning mechanisms
    • G01R33/307—Sample handling arrangements, e.g. sample cells, spinning mechanisms specially adapted for moving the sample relative to the MR system, e.g. spinning mechanisms, flow cells or means for positioning the sample inside a spectrometer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
    • G01R33/34—Constructional details, e.g. resonators, specially adapted to MR
    • G01R33/34046—Volume type coils, e.g. bird-cage coils; Quadrature bird-cage coils; Circularly polarised coils
    • G01R33/34053—Solenoid coils; Toroidal coils
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
    • G01R33/34—Constructional details, e.g. resonators, specially adapted to MR
    • G01R33/34092—RF coils specially adapted for NMR spectrometers

Abstract

An NMR system comprises an NMR probe comprising multiple NMR detection sites. Each of the multiple NMR detection sites comprises a sample holding void and an associated NMR microcoil. The NMR system further comprises a controllable fluid router operative to direct fluid sample to the multiple NMR detection sites.
PCT/US2001/046733 2000-12-01 2001-12-03 Microfluidic device with multiple microcoil nmr detectors WO2002056049A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2002241595A AU2002241595A1 (en) 2000-12-01 2001-12-03 Microfluidic device with multiple microcoil nmr detectors
EP01988273A EP1340094A2 (en) 2000-12-01 2001-12-03 Microfluidic device with multiple microcoil nmr detectors

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25087400P 2000-12-01 2000-12-01
US60/250,874 2000-12-01

Publications (2)

Publication Number Publication Date
WO2002056049A2 WO2002056049A2 (en) 2002-07-18
WO2002056049A3 true WO2002056049A3 (en) 2003-04-10

Family

ID=22949502

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/046733 WO2002056049A2 (en) 2000-12-01 2001-12-03 Microfluidic device with multiple microcoil nmr detectors

Country Status (4)

Country Link
US (3) US6822454B2 (en)
EP (1) EP1340094A2 (en)
AU (1) AU2002241595A1 (en)
WO (1) WO2002056049A2 (en)

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Also Published As

Publication number Publication date
EP1340094A2 (en) 2003-09-03
US20050253587A1 (en) 2005-11-17
US6822454B2 (en) 2004-11-23
US20020149369A1 (en) 2002-10-17
US7141978B2 (en) 2006-11-28
AU2002241595A1 (en) 2002-07-24
US20050030033A1 (en) 2005-02-10
WO2002056049A2 (en) 2002-07-18

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