WO2002064205A3 - Multi-electrode apparatus and method for treatment of congestive heart failure - Google Patents

Multi-electrode apparatus and method for treatment of congestive heart failure Download PDF

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Publication number
WO2002064205A3
WO2002064205A3 PCT/US2002/004330 US0204330W WO02064205A3 WO 2002064205 A3 WO2002064205 A3 WO 2002064205A3 US 0204330 W US0204330 W US 0204330W WO 02064205 A3 WO02064205 A3 WO 02064205A3
Authority
WO
WIPO (PCT)
Prior art keywords
electrodes
ventricular
treatment
heart
heart failure
Prior art date
Application number
PCT/US2002/004330
Other languages
French (fr)
Other versions
WO2002064205A2 (en
Inventor
Scott Mathis
John K Prentice
John A Schmidt
William B Rottenberg
Original Assignee
Quetzal Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quetzal Biomedical Inc filed Critical Quetzal Biomedical Inc
Priority to AU2002240363A priority Critical patent/AU2002240363A1/en
Publication of WO2002064205A2 publication Critical patent/WO2002064205A2/en
Publication of WO2002064205A3 publication Critical patent/WO2002064205A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/3627—Heart stimulators for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
    • A61N1/3684—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions for stimulating the heart at multiple sites of the ventricle or the atrium
    • A61N1/36842—Multi-site stimulation in the same chamber
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
    • A61N1/3686—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions configured for selecting the electrode configuration on a lead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
    • A61N1/3684—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions for stimulating the heart at multiple sites of the ventricle or the atrium

Abstract

An apparatus (100) and method for treatment of congestive heart failure from the right side of the heart. An implantable cardiac stimulation system (10) with a multi-electrode lead (14) having three or more selectable electrodes (E1, E2....En), together with apparatus for identifying an optimal subset of electrodes (114, 120, 124, 104), apparatus for shaping a propagating wave front, and apparatus for modifying the intrinsic ventricular cardiac activation sequence (104, 108, 118, 122, 126), or generating simultaneous or near simultaneous pacing pulses to the septum or right ventricular outflow tract during ventricular systole in order to improve left ventricular cardiac efficiency and reduce mitral regurgitation in patients with dilated cardiomyopathy. A three dimensional map of electrode placement may be calculated. A sub set of the available electrodes in the right side of the heart is selected for stimulation such that septal motion during systole is reduced or the mitral valve area is stiffened to reduce mitral regurgitation.
PCT/US2002/004330 2001-02-13 2002-02-13 Multi-electrode apparatus and method for treatment of congestive heart failure WO2002064205A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002240363A AU2002240363A1 (en) 2001-02-13 2002-02-13 Multi-electrode apparatus and method for treatment of congestive heart failure

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26844901P 2001-02-13 2001-02-13
US60/268,449 2001-02-13

Publications (2)

Publication Number Publication Date
WO2002064205A2 WO2002064205A2 (en) 2002-08-22
WO2002064205A3 true WO2002064205A3 (en) 2003-03-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/004330 WO2002064205A2 (en) 2001-02-13 2002-02-13 Multi-electrode apparatus and method for treatment of congestive heart failure

Country Status (3)

Country Link
US (2) US6643546B2 (en)
AU (1) AU2002240363A1 (en)
WO (1) WO2002064205A2 (en)

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