WO2003026611A3 - Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal - Google Patents
Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal Download PDFInfo
- Publication number
- WO2003026611A3 WO2003026611A3 PCT/US2002/030447 US0230447W WO03026611A3 WO 2003026611 A3 WO2003026611 A3 WO 2003026611A3 US 0230447 W US0230447 W US 0230447W WO 03026611 A3 WO03026611 A3 WO 03026611A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- solvent
- preparation
- liquid phase
- submicron sized
- sized nanoparticles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
Abstract
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003530248A JP2005504090A (en) | 2001-09-26 | 2002-09-25 | Preparation of submicron size-nanoparticles by removal of dispersion and solvent or liquid phase |
BR0212833-0A BR0212833A (en) | 2001-09-26 | 2002-09-25 | Preparation of submicron sized nanoparticles by dispersion and solvent or liquid phase removal |
CA2461349A CA2461349C (en) | 2001-09-26 | 2002-09-25 | Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal |
AU2002337692A AU2002337692B2 (en) | 2001-09-26 | 2002-09-25 | Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal |
EP02773579A EP1429749A2 (en) | 2001-09-26 | 2002-09-25 | Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal |
IL16057002A IL160570A0 (en) | 2001-09-26 | 2002-09-25 | Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal |
MXPA04002446A MXPA04002446A (en) | 2001-09-26 | 2002-09-25 | Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal. |
IL196631A IL196631A (en) | 2001-09-26 | 2009-01-21 | Process for preparing submicron sized particles via dispersion and solvent or liquid phase removal |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/964,273 US20060003012A9 (en) | 2001-09-26 | 2001-09-26 | Preparation of submicron solid particle suspensions by sonication of multiphase systems |
US09/964,273 | 2001-09-26 | ||
US10/183,035 | 2002-06-26 | ||
US10/183,035 US6835396B2 (en) | 2001-09-26 | 2002-06-26 | Preparation of submicron sized nanoparticles via dispersion lyophilization |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003026611A2 WO2003026611A2 (en) | 2003-04-03 |
WO2003026611A3 true WO2003026611A3 (en) | 2003-07-03 |
Family
ID=26878679
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/030447 WO2003026611A2 (en) | 2001-09-26 | 2002-09-25 | Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal |
Country Status (10)
Country | Link |
---|---|
US (1) | US8722091B2 (en) |
EP (1) | EP1429749A2 (en) |
JP (1) | JP2005504090A (en) |
CN (1) | CN1558755A (en) |
AU (1) | AU2002337692B2 (en) |
BR (1) | BR0212833A (en) |
CA (1) | CA2461349C (en) |
IL (1) | IL160570A0 (en) |
MX (1) | MXPA04002446A (en) |
WO (1) | WO2003026611A2 (en) |
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US6835396B2 (en) | 2001-09-26 | 2004-12-28 | Baxter International Inc. | Preparation of submicron sized nanoparticles via dispersion lyophilization |
US8067032B2 (en) | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
US8722091B2 (en) | 2001-09-26 | 2014-05-13 | Baxter International Inc. | Preparation of submicron sized nanoparticles via dispersion lyophilization |
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- 2002-09-25 JP JP2003530248A patent/JP2005504090A/en active Pending
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- 2002-09-25 CN CNA028189590A patent/CN1558755A/en active Pending
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Cited By (3)
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US8067032B2 (en) | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
US6835396B2 (en) | 2001-09-26 | 2004-12-28 | Baxter International Inc. | Preparation of submicron sized nanoparticles via dispersion lyophilization |
US8722091B2 (en) | 2001-09-26 | 2014-05-13 | Baxter International Inc. | Preparation of submicron sized nanoparticles via dispersion lyophilization |
Also Published As
Publication number | Publication date |
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IL160570A0 (en) | 2004-07-25 |
WO2003026611A2 (en) | 2003-04-03 |
CA2461349C (en) | 2011-11-29 |
BR0212833A (en) | 2004-10-13 |
JP2005504090A (en) | 2005-02-10 |
CA2461349A1 (en) | 2003-04-03 |
MXPA04002446A (en) | 2004-07-23 |
US20050013868A1 (en) | 2005-01-20 |
CN1558755A (en) | 2004-12-29 |
EP1429749A2 (en) | 2004-06-23 |
US8722091B2 (en) | 2014-05-13 |
AU2002337692B2 (en) | 2007-09-13 |
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