WO2003039326A3 - Method for noninvasive continuous determination of physiologic characteristics - Google Patents
Method for noninvasive continuous determination of physiologic characteristics Download PDFInfo
- Publication number
- WO2003039326A3 WO2003039326A3 PCT/US2001/046855 US0146855W WO03039326A3 WO 2003039326 A3 WO2003039326 A3 WO 2003039326A3 US 0146855 W US0146855 W US 0146855W WO 03039326 A3 WO03039326 A3 WO 03039326A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- blood
- level sensor
- converter
- patient
- changes
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000008280 blood Substances 0.000 abstract 4
- 210000004369 blood Anatomy 0.000 abstract 4
- 230000036772 blood pressure Effects 0.000 abstract 2
- 239000000523 sample Substances 0.000 abstract 2
- 238000002835 absorbance Methods 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6825—Hand
- A61B5/6826—Finger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/02028—Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
- A61B5/02055—Simultaneously evaluating both cardiovascular condition and temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring pH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4821—Determining level or depth of anaesthesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/683—Means for maintaining contact with the body
- A61B5/6838—Clamps or clips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0242—Operational features adapted to measure environmental factors, e.g. temperature, pollution
- A61B2560/0247—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value
- A61B2560/0261—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value using hydrostatic pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/024—Detecting, measuring or recording pulse rate or heart rate
- A61B5/02416—Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
- A61B5/0285—Measuring or recording phase velocity of blood waves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
- A61B5/029—Measuring or recording blood output from the heart, e.g. minute volume
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14552—Details of sensors specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/369—Electroencephalography [EEG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/389—Electromyography [EMG]
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002466012A CA2466012A1 (en) | 2001-11-07 | 2001-11-07 | Method for noninvasive continuous determination of physiologic characteristics |
JP2003541424A JP2005507298A (en) | 2001-11-07 | 2001-11-07 | A non-invasive method for continuous measurement of physiological characteristics |
PCT/US2001/046855 WO2003039326A2 (en) | 2001-11-07 | 2001-11-07 | Method for noninvasive continuous determination of physiologic characteristics |
MXPA04004286A MXPA04004286A (en) | 2001-11-07 | 2001-11-07 | Method for noninvasive continuous determination of physiologic characteristics. |
AU2001297917A AU2001297917B2 (en) | 2001-11-07 | 2001-11-07 | Method for noninvasive continuous determination of physiologic characteristics |
EP01274207A EP1450672A4 (en) | 2001-11-07 | 2001-11-07 | Method for noninvasive continuous determination of physiologic characteristics |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2001/046855 WO2003039326A2 (en) | 2001-11-07 | 2001-11-07 | Method for noninvasive continuous determination of physiologic characteristics |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2003039326A2 WO2003039326A2 (en) | 2003-05-15 |
WO2003039326A3 true WO2003039326A3 (en) | 2003-07-24 |
WO2003039326A8 WO2003039326A8 (en) | 2007-09-07 |
Family
ID=21743081
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/046855 WO2003039326A2 (en) | 2001-11-07 | 2001-11-07 | Method for noninvasive continuous determination of physiologic characteristics |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1450672A4 (en) |
JP (1) | JP2005507298A (en) |
AU (1) | AU2001297917B2 (en) |
CA (1) | CA2466012A1 (en) |
MX (1) | MXPA04004286A (en) |
WO (1) | WO2003039326A2 (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7684842B2 (en) | 2006-09-29 | 2010-03-23 | Nellcor Puritan Bennett Llc | System and method for preventing sensor misuse |
US8219170B2 (en) | 2006-09-20 | 2012-07-10 | Nellcor Puritan Bennett Llc | System and method for practicing spectrophotometry using light emitting nanostructure devices |
US8265724B2 (en) | 2007-03-09 | 2012-09-11 | Nellcor Puritan Bennett Llc | Cancellation of light shunting |
US8280469B2 (en) | 2007-03-09 | 2012-10-02 | Nellcor Puritan Bennett Llc | Method for detection of aberrant tissue spectra |
US8315685B2 (en) | 2006-09-27 | 2012-11-20 | Nellcor Puritan Bennett Llc | Flexible medical sensor enclosure |
US8600469B2 (en) | 2005-09-29 | 2013-12-03 | Covidien Lp | Medical sensor and technique for using the same |
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US9468378B2 (en) | 1997-01-27 | 2016-10-18 | Lawrence A. Lynn | Airway instability detection system and method |
US9042952B2 (en) | 1997-01-27 | 2015-05-26 | Lawrence A. Lynn | System and method for automatic detection of a plurality of SPO2 time series pattern types |
US8932227B2 (en) | 2000-07-28 | 2015-01-13 | Lawrence A. Lynn | System and method for CO2 and oximetry integration |
US9521971B2 (en) | 1997-07-14 | 2016-12-20 | Lawrence A. Lynn | System and method for automatic detection of a plurality of SPO2 time series pattern types |
US20060195041A1 (en) | 2002-05-17 | 2006-08-31 | Lynn Lawrence A | Centralized hospital monitoring system for automatically detecting upper airway instability and for preventing and aborting adverse drug reactions |
US9053222B2 (en) | 2002-05-17 | 2015-06-09 | Lawrence A. Lynn | Patient safety processor |
GB0213836D0 (en) * | 2002-06-14 | 2002-07-24 | Electrode Company The Ltd | Analytical apparatus |
KR100624412B1 (en) * | 2003-09-16 | 2006-09-18 | 삼성전자주식회사 | Blood components measuring apparatus and method of measuring blood components using the same |
JP2006231012A (en) * | 2005-01-28 | 2006-09-07 | Nippon Koden Corp | Method and apparatus for measuring circulation time of oxygen delivery |
US7641614B2 (en) | 2005-08-22 | 2010-01-05 | Massachusetts Institute Of Technology | Wearable blood pressure sensor and method of calibration |
US7674231B2 (en) | 2005-08-22 | 2010-03-09 | Massachusetts Institute Of Technology | Wearable pulse wave velocity blood pressure sensor and methods of calibration thereof |
US7869850B2 (en) | 2005-09-29 | 2011-01-11 | Nellcor Puritan Bennett Llc | Medical sensor for reducing motion artifacts and technique for using the same |
ITMI20070464A1 (en) * | 2007-03-09 | 2008-09-10 | Vittorio Londoni | DIODIC LASER DEVICE FOR INCRUABLE DETERMINATION OF GLYCEMIA |
US8750953B2 (en) | 2008-02-19 | 2014-06-10 | Covidien Lp | Methods and systems for alerting practitioners to physiological conditions |
WO2009137682A1 (en) | 2008-05-07 | 2009-11-12 | Lynn Lawrence A | Medical failure pattern search engine |
US8295567B2 (en) | 2008-06-30 | 2012-10-23 | Nellcor Puritan Bennett Ireland | Systems and methods for ridge selection in scalograms of signals |
US9895068B2 (en) | 2008-06-30 | 2018-02-20 | Covidien Lp | Pulse oximeter with wait-time indication |
US8968193B2 (en) | 2008-09-30 | 2015-03-03 | Covidien Lp | System and method for enabling a research mode on physiological monitors |
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US8313439B2 (en) | 2009-03-20 | 2012-11-20 | Massachusetts Institute Of Technology | Calibration of pulse transit time measurements to arterial blood pressure using external arterial pressure applied along the pulse transit path |
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JP5302257B2 (en) * | 2010-04-05 | 2013-10-02 | 建夫 斎藤 | Tissue blood flow measuring device and tissue blood flow measuring program |
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US11399898B2 (en) | 2012-03-06 | 2022-08-02 | Briteseed, Llc | User interface for a system used to determine tissue or artifact characteristics |
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US10827961B1 (en) | 2012-08-29 | 2020-11-10 | Masimo Corporation | Physiological measurement calibration |
US9241646B2 (en) | 2012-09-11 | 2016-01-26 | Covidien Lp | System and method for determining stroke volume of a patient |
JP6055688B2 (en) | 2013-01-31 | 2016-12-27 | 日本光電工業株式会社 | Biosignal measurement system, biosignal measurement device, and control program for biosignal measurement device |
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JP6511471B2 (en) | 2014-03-25 | 2019-05-15 | ブライトシード・エルエルシーBriteseed,Llc | Vessel detector and detection method |
US10820838B2 (en) | 2015-02-19 | 2020-11-03 | Briteseed, Llc | System for determining vessel size using light absorption |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4968137A (en) * | 1986-12-05 | 1990-11-06 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University | Devices and procedures for in vitro testing of pulse oximetry monitors |
US5638816A (en) * | 1995-06-07 | 1997-06-17 | Masimo Corporation | Active pulse blood constituent monitoring |
US5964701A (en) * | 1996-10-24 | 1999-10-12 | Massachusetts Institute Of Technology | Patient monitoring finger ring sensor |
US5978691A (en) * | 1996-07-19 | 1999-11-02 | Mills; Alexander Knight | Device and method for noninvasive continuous determination of blood gases, pH, hemoglobin level, and oxygen content |
US6222189B1 (en) * | 1992-07-15 | 2001-04-24 | Optix, Lp | Methods of enhancing optical signals by mechanical manipulation in non-invasive testing |
US6334065B1 (en) * | 1998-06-03 | 2001-12-25 | Masimo Corporation | Stereo pulse oximeter |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5372136A (en) * | 1990-10-06 | 1994-12-13 | Noninvasive Medical Technology Corporation | System and method for noninvasive hematocrit monitoring |
JP3116252B2 (en) * | 1992-07-09 | 2000-12-11 | 日本光電工業株式会社 | Pulse oximeter |
NZ518142A (en) * | 1999-10-07 | 2003-11-28 | Alexander K | Optical determination of blood characteristics accounting for heart/limb relative height |
-
2001
- 2001-11-07 MX MXPA04004286A patent/MXPA04004286A/en active IP Right Grant
- 2001-11-07 CA CA002466012A patent/CA2466012A1/en not_active Abandoned
- 2001-11-07 WO PCT/US2001/046855 patent/WO2003039326A2/en active Application Filing
- 2001-11-07 EP EP01274207A patent/EP1450672A4/en not_active Withdrawn
- 2001-11-07 JP JP2003541424A patent/JP2005507298A/en active Pending
- 2001-11-07 AU AU2001297917A patent/AU2001297917B2/en not_active Ceased
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4968137A (en) * | 1986-12-05 | 1990-11-06 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University | Devices and procedures for in vitro testing of pulse oximetry monitors |
US6222189B1 (en) * | 1992-07-15 | 2001-04-24 | Optix, Lp | Methods of enhancing optical signals by mechanical manipulation in non-invasive testing |
US5638816A (en) * | 1995-06-07 | 1997-06-17 | Masimo Corporation | Active pulse blood constituent monitoring |
US5978691A (en) * | 1996-07-19 | 1999-11-02 | Mills; Alexander Knight | Device and method for noninvasive continuous determination of blood gases, pH, hemoglobin level, and oxygen content |
US5964701A (en) * | 1996-10-24 | 1999-10-12 | Massachusetts Institute Of Technology | Patient monitoring finger ring sensor |
US6334065B1 (en) * | 1998-06-03 | 2001-12-25 | Masimo Corporation | Stereo pulse oximeter |
Non-Patent Citations (1)
Title |
---|
See also references of EP1450672A4 * |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8600469B2 (en) | 2005-09-29 | 2013-12-03 | Covidien Lp | Medical sensor and technique for using the same |
US8219170B2 (en) | 2006-09-20 | 2012-07-10 | Nellcor Puritan Bennett Llc | System and method for practicing spectrophotometry using light emitting nanostructure devices |
US8315685B2 (en) | 2006-09-27 | 2012-11-20 | Nellcor Puritan Bennett Llc | Flexible medical sensor enclosure |
US7684842B2 (en) | 2006-09-29 | 2010-03-23 | Nellcor Puritan Bennett Llc | System and method for preventing sensor misuse |
US8265724B2 (en) | 2007-03-09 | 2012-09-11 | Nellcor Puritan Bennett Llc | Cancellation of light shunting |
US8280469B2 (en) | 2007-03-09 | 2012-10-02 | Nellcor Puritan Bennett Llc | Method for detection of aberrant tissue spectra |
Also Published As
Publication number | Publication date |
---|---|
CA2466012A1 (en) | 2003-05-15 |
AU2001297917B2 (en) | 2007-11-01 |
WO2003039326A2 (en) | 2003-05-15 |
WO2003039326A8 (en) | 2007-09-07 |
MXPA04004286A (en) | 2004-09-10 |
AU2001297917A1 (en) | 2003-05-19 |
JP2005507298A (en) | 2005-03-17 |
EP1450672A2 (en) | 2004-09-01 |
EP1450672A4 (en) | 2005-06-22 |
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