WO2004010858A2 - Self-propelled imaging system - Google Patents

Self-propelled imaging system Download PDF

Info

Publication number
WO2004010858A2
WO2004010858A2 PCT/IL2003/000627 IL0300627W WO2004010858A2 WO 2004010858 A2 WO2004010858 A2 WO 2004010858A2 IL 0300627 W IL0300627 W IL 0300627W WO 2004010858 A2 WO2004010858 A2 WO 2004010858A2
Authority
WO
WIPO (PCT)
Prior art keywords
carrier
imaging system
expandable element
expandable
imaging
Prior art date
Application number
PCT/IL2003/000627
Other languages
French (fr)
Other versions
WO2004010858A3 (en
Inventor
Yosef Gross
Benad Goldwasser
Oz Cabiri
Original Assignee
Gi View Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/302,897 external-priority patent/US6988986B2/en
Application filed by Gi View Ltd. filed Critical Gi View Ltd.
Priority to JP2004524045A priority Critical patent/JP4541888B2/en
Priority to US10/523,578 priority patent/US20060201351A1/en
Priority to EP03741050A priority patent/EP1526802A2/en
Priority to AU2003281767A priority patent/AU2003281767A1/en
Publication of WO2004010858A2 publication Critical patent/WO2004010858A2/en
Publication of WO2004010858A3 publication Critical patent/WO2004010858A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/005Flexible endoscopes
    • A61B1/0051Flexible endoscopes with controlled bending of insertion part
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00147Holding or positioning arrangements
    • A61B1/00156Holding or positioning arrangements using self propulsion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/31Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the rectum, e.g. proctoscopes, sigmoidoscopes, colonoscopes

Definitions

  • the present invention relates generally to medical imaging systems, and particularly to a self-propelled imaging system, suitable for imaging body lumens, such as the gastrointestinal (GI) tract.
  • GI gastrointestinal
  • GI gastrointestinal
  • endoscopy is widely used for observing, photographing tissue, and taking specimens from lesions and the like.
  • the endoscope is typically manually inserted into the colon.
  • patients may often complain of abdominal pain and distention because the colon is extended or excessively dilated, thereby necessitating stopping the endoscopic procedure.
  • Insertion of an endoscope through the sigmoid colon and into the descending colon, or through the splenic flexure, the transverse colon, the hepatic flexure or parts affected by previous operations may also be accompanied with difficulty. Because of these reasons, a colonoscopy is typically performed by a relatively few number of skilled practitioners, and the rate of patient pain and discomfort is high.
  • US Patent 5,337,732 to Grundfest et al. describes a robot for performing endoscopic procedures, which includes a plurality of segments attached to each other through an articulated joint. Actuators can move the segments together and apart and change their angular orientation to allow the robot to move in an inchworm or snake-like fashion through a cavity or lumen within a patient. Inflatable balloons around the segments inflate to brace a temporarily stationary segment against the lumen walls while other segments move. A compressed gas line attached to the back segment provides compressed gas to inflate the balloons and optionally to drive the actuators.
  • the lead segment includes a television camera and biopsy arm or other sensors and surgical instruments.
  • the present invention seeks to provide an improved imaging system which is self- propelled, suitable for imaging body lumens, such as the gastrointestinal (GI) tract.
  • the imaging system of the invention may be sterile and disposable, and may be manufactured at very low cost.
  • the system causes virtually no pain to the patient, being of very low friction and providing maximum comfort and flexibility.
  • the system provides excellent visibility and full movement control.
  • the imaging system of the present invention may comprise an imaging device assembled on a carrier.
  • First and second outwardly expandable elements may be mounted on the carrier.
  • the second expandable element may be expanded both radially and axially.
  • obstruction of the radial expansion of the second expandable element causes the axial expansion of the second expandable element to propel the carrier and the imaging device axially, as is described more in detail hereinbelow.
  • the imaging system may thus self-propel distally into the body lumen without any need for knowing the local diameter of the body lumen. Other embodiments are also described hereinbelow.
  • Fig. 1 A is a simplified pictorial and cut-away illustration of an imaging system, constructed and operative in accordance with an embodiment of the present invention, in a contracted orientation;
  • Fig. IB is a simplified pictorial illustration of a distal end of the imaging system of Fig. 1A;
  • Fig. 1C is a simplified sectional illustration of the imaging system of Fig. 1A;
  • Figs. 1D-1G are simplified pictorial illustrations of the imaging system of Fig. 1 A, showing four steps of a mode of operation thereof, wherein in Fig. ID a proximal expandable element and a distal expandable element are both contracted, in Fig. IE the proximal expandable element expands generally spherically, in Fig. IF the distal and proximal expandable elements are both expanded, and in Fig. 1G the distal expandable element is expanded while the proximal expandable element is contracted;
  • FIG. 2 is a simplified side-view illustration of the imaging system of Fig. 1A inserted in a body lumen in a contracted orientation, prior to self-propulsion therethrough, in accordance with an embodiment of the present invention
  • Fig. 3 is a simplified side-view illustration of the imaging system of Fig. 1A with the proximal expandable element partially expanded and not yet touching the inner wall of the body lumen;
  • Fig. 4 is a simplified side-view illustration of the imaging system of Fig. 1A with the proximal expandable element further expanded and touching the inner wall of the body lumen;
  • Fig. 5 is a simplified side-view illustration of the imaging system of Fig. 1A with the proximal expandable element further expanded, pressing against the inner wall of the body lumen, and propelling the imaging system distally through the body lumen;
  • Fig. 6 is a simplified pictorial and cut-away illustration of the imaging system of Fig. 1A in the orientation of Fig. 4 or 5;
  • Fig. 7 is a simplified pictorial and cut-away illustration of the imaging system of Fig. 1A with the proximal expandable element expanded and a distal expandable element also expanded, in accordance with an embodiment of the present invention
  • Fig. 8 is a simplified pictorial and cut-away illustration of the imaging system of Fig. 1A with the proximal expandable element contracted and the distal expandable element expanded, in accordance with an embodiment of the present invention
  • FIGs. 9 and 10 are simplified pictorial and cut-away illustrations, respectively, of an imaging system, constructed and operative in accordance with another embodiment of the present invention, comprising an expandable element mounted on a carrier;
  • Figs. 11 and 12 are simplified pictorial and side-view sectional illustrations, respectively, of the imaging system of Figs. 9 and 10, with the expandable element extended distally relative to the carrier;
  • Fig. 13 is a simplified pictorial illustration of an imaging system, constructed and operative in accordance with another embodiment of the present invention, comprising a jet-action head mounted on a carrier;
  • Figs. 14-16 are simplified pictorial illustrations of an imaging system, constructed and operative in accordance with yet another embodiment of the present invention, comprising traction members extending from a carrier, wherein in the embodiment illustrated in Fig. 14, the traction members have a helical shape, in Fig. 15, the traction members extend towards a proximal end of the carrier, and in Fig. 16, the traction members extend towards a distal end of the carrier; and
  • Fig. 17 is a simplified pictorial illustration of an imaging system, constructed and operative in accordance with still another embodiment of the present invention, comprising a percussion device mounted on a carrier.
  • FIG. 1A illustrates an imaging system 10, constructed and operative in accordance with an embodiment of the present invention.
  • Imaging system 10 may comprise first and second outwardly expandable elements 12 and 14.
  • One of the outwardly expandable elements may be the proximal element and the other one may be the distal element.
  • first element 12 is the distal element that enters the body lumen first
  • second element 14 is the proximal element that enters the body lumen last.
  • first and second expandable elements 12 and 14 expand to different shapes.
  • First expandable element 12 may expand substantially radially with negligible axial expansion.
  • second expandable element 14 may expand both radially and axially, such as expanding generally spherically.
  • First and second expandable elements 12 and 14 may be mounted coaxially on a carrier 16.
  • Carrier 16 may be made of any suitable, flexible, medically approved material, and may take the form of a tube.
  • the expandable elements 12 and 14 may comprise full circumference or partial circumference elements.
  • Each expandable element 12 or 14 may comprise an inflatable, elastomeric tubular element formed with annular rings 18.
  • Each expandable element 12 or 14 may be mounted in a pair of collar elements 20, wherein the annular rings 18 are received in annular grooves 22 formed in collar elements 20.
  • Annular ring 18 may be held in groove 22 by means of an annular fastener 21, which snaps together with tongues 19 axially protruding from collar element 20.
  • Collar elements 20 may be formed separately for each expandable element, and may be adjoined together by snapping together or by means of fasteners or any other suitable method.
  • a single collar element 20 may be placed between first and second expandable elements 12 and 14, wherein the single collar element 20 has two sets of annular grooves 22 to receive therein the proximal annular ring 18 of the distal expandable element 12 and the distal annular ring 18 of the proximal expandable element 14.
  • the collar elements 20 may be flexible and resilient to permit passage of imaging system 10 through folds of the GI tract.
  • An O-ring 23 may slidingly seal the most proximal collar element 20 with respect to carrier 16. Accordingly, the collar elements 20 at the ends of first expandable element 12 may be fixed axially with respect to carrier 16, thereby preventing first expandable element 12 from expanding axially. In contrast, second expandable element 14 may slide axially relative to carrier 16.
  • first expandable element 12 may expand both radially and axially, if desired, instead of second expandable element 14, which may cause imaging system 10 to move in a proximal direction instead of a distal direction.
  • Carrier 16 may be formed with a distal aperture 24 and a proximal aperture 26.
  • a first supply tube 28 may be introduced through carrier 16 in fluid communication with distal aperture 24.
  • a second supply tube 30 may be introduced through earner 16 in fluid communication with proximal aperture 26.
  • First expandable element 12 may be expanded outwards by introducing therein a fluid, such as but not limited to, air or water, by means of first supply tube 28 via distal aperture 24.
  • second expandable element 14 may be expanded outwards by introducing therein a fluid (which may or may not be the same fluid used to expand first expandable element 12), by means of second supply tube 30 via proximal aperture 26.
  • An imaging device 32 such as but not limited to, a CCD (charge coupled device) or CMOS (complementary metal oxide semiconductor) camera, may be mounted at a distal end of imaging system 10.
  • imaging device 32 may be mounted in the most distal collar element 20, which may be formed with a viewing window 34 through which images may be captured.
  • Imaging device 32 and viewing window 34 may be oriented for capturing images either axially or radially with respect to carrier 16.
  • a light source 36 may be provided for imaging device 32, wherein electrical wiring and/or optic fibers 38 (Fig. 1C) may be fed through carrier 16 to imaging device 32 and light source 36.
  • Imaging device 32 may be connected to an imaging processor (not shown) by optical fibers.
  • a control system (not shown) may be provided that oversees and controls the expansion/contraction of the expandable elements 12 and 14, and other functions of imaging system 10, such as but not limited to, the timing and amount of the expansion/contraction of the expandable elements 12 and 14.
  • a suction tube 40 (Fig. IB) may be provided for sucking debris or other material.
  • a tool lumen 42 may be provided for introducing therethrough mechanical devices and/or sensors (not shown), such as but not limited to, cutting devices for cutting and collecting materials for biopsies and the like, and biosensors.
  • passageways 44 may be provided for passing therethrough control wires 46 for directing the imaging system 10 through tight bends and the like.
  • a guide member 50 (Fig. 1C) may be disposed at the proximal end of carrier 16.
  • Guide member 50 may be funnel-shaped, for example, for comfortable placement in a rectum of a patient (not shown).
  • a linear encoder 52 may be disposed at the proximal end of carrier 16 and pass through guide member 50.
  • Linear encoder 52 may comprise markings and the like detectable by a decoder 54 mounted on guide member 50. Decoder 54 may sense linear movement of carrier 16 with respect to linear encoder 52, which movement is described in greater detail hereinbelow.
  • imaging system 10 may wirelessly transmit or receive data to or from an external processor (not shown).
  • FIGs. 1D-1G and Figs. 2-5 illustrate imaging system 10 in different orientations for self-propulsion through a body lumen 60, such as but not limited to, the colon, in accordance with an embodiment of the present invention.
  • body lumen 60 is omitted in Figs. 1D-1G for clarity.
  • imaging system 10 may be inserted in body lumen 60.
  • second (proximal) expandable element 14 may be expanded outwardly.
  • O-ring 23 slides proximally along carrier 16, as indicated by arrow 53, with the result that carrier 16 (along with imaging device 32) does not yet advance in body lumen 60.
  • proximal expandable element 14 has expanded sufficiently so that it touches the inner wall of body lumen 60.
  • Carrier 16 (along with imaging device 32) has still not advanced in body lumen 60, and O-ring 23 has continued to slide proximally along carrier 16, as indicated by arrow 53.
  • the orientation of Fig. 4 is shown in pictorially in Fig. 6.
  • the proximal expandable element 14 continues to expand. Since the proximal expandable element 14 has already contacted the inner wall of body lumen 60, the continued expansion of expandable element 14 presses it against the inner wall of body lumen 60. The friction between expandable element 14 and the inner wall resists the radial expansion, with the result that most of the expansion of the proximal expandable element 14 is in the axial direction, as indicated by double arrow 57. This causes carrier
  • carrier 16 (along with imaging device 32) to advance distally in body lumen 60, as indicated by arrow 62, by a distance ⁇ in Fig. 5.
  • the distal advancement of carrier 16 relative to guide member 50 may be detected by linear encoder 52 and decoder 54 (seen also in Fig. IE).
  • second expandable element 14 may advance the carrier 16 distally in body lumen 60, without any need for sensing when second expandable element 14 has actually contacted the inner wall of body lumen 60. Rather once second expandable element 14 presses against the inner wall of body lumen 60, further expansion of second expandable element 14 may advance the carrier 16 distally in body lumen 60.
  • the control system may control the further expansion of second expandable element 14 in order to control the amount of incremental advancement of carrier 16 and imaging device 32.
  • first (distal) expandable element 12 may be expanded radially. Both first and second expandable elements 12 and 14 now press against the inner wall of body lumen 60 (not shown in Fig. 7) and fix imaging system 10 in place in lumen 60.
  • second expandable element 14 may be contracted inwardly (e.g., deflated) so that it no longer presses against the inner wall of body lumen 60 (not shown in Fig. 8). Images may be captured by imaging device 32 at either of the orientations shown in Figs. 7 and 8. As seen best in Fig. 1G, second expandable element 14 advances distally along carrier 16 when it is contracted inwardly, as indicated by arrow 67.
  • first expandable element 12 may be contracted so that imaging system 10 returns to the contracted orientation of Fig. 2, and the operating cycle may be repeated to incrementally advance imaging system 10 through body lumen 60.
  • the user or control system may ensure that carrier 16 does not move back proximally at each increment distal advance.
  • first expandable element 12 may initially remain expanded against the inner wall of body lumen 60 while re-expanding second expandable element 14, and then first expandable element 12 may be contracted so as not to impede the incremental distal advancement caused by the re-expansion of second expandable element 14.
  • the control system may control the timing of the contraction of the first expandable element 12 and the expansion of the second expandable element 14.
  • Imaging system 10 may be contracted to the orientation of Fig. 2 for removal from body lumen 60.
  • FIG. 9-12 illustrate an imaging system 70, constructed and operative in accordance with an embodiment of the present invention.
  • Imaging system 70 may comprise a carrier 72, such as in the form of a tube, to which a stopper 74 is mounted at a distal portion thereof.
  • An expandable element 82 may be at a distal portion of carrier 72 in fluid communication with a fluid source (not shown) via one or more apertures 80.
  • Expandable element 82 and carrier 72 may comprise an elastic, flexible member folded into itself, wherein the expandable element 82 is at the distal end and the carrier 72 extends proximally therefrom.
  • An O-ring 78 may seal expandable element 82 with respect to the rest of carrier 72 (Fig. 12). Fluid 79 may flow through aperture 80 to at least partially fill expandable element 82 (Fig. 12).
  • Expandable element 82 may comprise a flexible sleeve, such as a sleeve made of an elastomeric material (e.g., rubber, latex, etc.).
  • Imaging system 70 may be inserted in a body lumen, e.g., rectum of a patient (not shown), wherein stopper 74 abuts against the anus (not shown). Fluid 79 may then be introduced via aperture 80 to at least partially fill the flexible sleeve, thereby expanding expandable element 82 relative to carrier 72 and further into the colon (not shown). The portion of carrier 72 proximal to stopper 74 may be drawn distally into the colon by the expansion of expandable element 82.
  • Carrier 72 may have a lumen 76 for passage therethrough of an instrument 84, such as but not limited to, imaging devices (e.g., camera, x-ray imaging device), illumination devices, biopsy collecting tools, optical devices, fluid devices, etc.
  • the instrument 84 may pass all the way through lumen 76 and through a distal aperture 73. In this manner, for example, an imaging device may be introduced through carrier 72 to provide images of the colon.
  • FIG. 13 illustrates an imaging system 90, constructed and operative in accordance with another embodiment of the present invention.
  • Imaging system 90 may comprise a carrier 92, such as in the form of a tube, comprising a fluid passageway 93 for passage of a fluid 94 (liquid or gas) therethrough.
  • a jet-action head 95 may be mounted on a distal end 91 of carrier 92. Jet-action head 95 may be formed with fluid jet outlets 96 facing a proximal end of carrier 92, which are in fluid communication with fluid passageway 93.
  • An imaging device 97 may be disposed in jet-action head 95. As mentioned similarly above, imaging device 97 may comprise, without limitation, illumination devices, biopsy devices, other tools, etc. Imaging device
  • jet-action head 95 may comprise a camera, in which case jet-action head 95 is preferably transparent.
  • Imaging device 97 may alternatively comprise an x-ray imaging device, for example.
  • Imaging system 90 may be inserted in a rectum of a patient (not shown), and fluid 94 introduced in fluid passageway 93 (from a fluid source, not shown) exits fluid jet outlets 96 to propel imaging system 90 in the body lumen, e.g., colon (not shown).
  • Jet-action head 95 may be expandable and contractible, such as made of an elastomeric material. Alternatively, jet-action head 95 may be made of a rigid material, such as but not limited to, plastic or metal. Jet-action head 95 may comprise a magnet 98 for attaching to an imaging device (capsule or bolus) in the gastrointestinal tract (not shown). Any of the other embodiments of the present invention may also comprise a magnet like magnet 98.
  • Imaging system 100 may comprise a carrier 102, such as in the form of a tube, which comprises one or more traction members 104.
  • Traction member 104 may comprise a loop 106 extending from carrier 102.
  • An actuator 108 may be in operative communication with traction member 104.
  • Actuator 108 may comprise, without limitation, a servomotor, gear motor, step motor and the like.
  • loop 106 may have a helical shape that at least partially corkscrews around a periphery of carrier 102.
  • loop 106 protrudes from a side of carrier 102 and extends towards a proximal end 109 of carrier 102.
  • loop 106 protrudes from a side of carrier 102 and extends towards a distal end 111 of carrier 102. It is appreciated that these are just some examples of possible loops and the invention is not limited to these examples.
  • the traction members 104 may be provided in any amount, size and shape.
  • Actuator 108 may move loop 106 relative to carrier 102.
  • loop 106 may be rotated about its own axis (as indicated by arrows 112).
  • loops 106 may be rotated like the track of a tracked vehicle.
  • the rotational movement of loops 106 against the inner wall of the body lumen, e.g., colon (not shown) propels and advances imaging system 100 through the colon.
  • loop 106 may be expandable and contractible, such as by means of a fluid introduced therein through appropriate fluid passageways (not shown) in carrier 102, as similarly described hereinabove for the embodiment of Figs. 9-12.
  • components may be inflated to improve the view for imaging.
  • Imaging device 116 (seen in the embodiment of Fig. 16) may be disposed in carrier 102.
  • Imaging device 116 may comprise a camera, in which case the distal end of carrier 102 is preferably transparent.
  • Imaging device 116 may alternatively comprise an x-ray imaging device.
  • the components of the system may be energized by an internal or external power source, and may comprise a transmitter and/ or receiver to an external device.
  • the elements that move in the body lumen may be shaped or may comprise structure that preferentially facilitate movement in one direction (e.g., in the distal direction) as opposed to the opposite direction (e.g., in the proximal direction).
  • Such structure may comprise, without limitation, inflatable protrusions or spurs, which when deflated or contracted, permit movement in the opposite direction (e.g., in the proximal direction).
  • FIG. 17 illustrates an imaging system 120, constructed and operative in accordance with another embodiment of the present invention.
  • Imaging system 120 may comprise a carrier 122, such as in the form of a tube.
  • a percussion device 124 may be mounted on a distal portion of carrier 122.
  • Percussion device 124 may comprise, without limitation, a vibrator, an oscillator, a solenoid device, a pneumatic, hydraulic, or electromechanical hammering device and the like.
  • Percussion device 124 may contain its own power source (e.g., battery) or may be operated by an external actuator (not shown). Oscillation or vibration of percussion device 124, indicated by arrows 126, against the inner wall of the body lumen, e.g., colon (not shown), propels and advances imaging system 120 through the colon.
  • An imaging device 128 may be disposed in the distal portion of carrier 122.
  • Imaging device 128 may comprise a camera, in which case the distal end of carrier 122 is preferably transparent.
  • Imaging device 128 may alternatively comprise an x-ray imaging device.
  • carrier 122 as a guide member or wire for a catheter-like procedure (as similarly used in angioplasty procedures), wherein an instrument may be introduced in or over carrier 122.
  • an outer catheter 129 may be slipped over carrier 122.
  • An instrument 127 may be introduced over carrier 122, on either side of percussion device 124, and may be pushed distally by any suitable means.
  • instrument 84 the instrument
  • carrier 127 may comprise, without limitation, a torus-shaped camera (CCD) or other imaging device (e.g., x-ray imaging device), illumination device, biopsy collecting tool, optical device, fluid device, etc.
  • CCD torus-shaped camera
  • imaging device e.g., x-ray imaging device

Abstract

An imaging system comprising an imaging device assembled on a carrier, and a first outwardly expandable element and a second outwardly expandable element mounted on the carrier, wherein the second expandable element is expandable both radially and axially, the imaging system comprising a mode of operation, wherein during expansion of the second expandable element, obstruction of the radial expansion of the second expandable element causes the axial expansion of the second expandable element to propel the carrier and the imaging device axially. Other embodiments are also described.

Description

SELF-PROPELLED IMAGING SYSTEM FIELD OF THE INVENTION
The present invention relates generally to medical imaging systems, and particularly to a self-propelled imaging system, suitable for imaging body lumens, such as the gastrointestinal (GI) tract.
BACKGROUND OF THE INVENTION
Many imaging devices are known for producing medical images of body lumens, such as the gastrointestinal (GI) tract. For example, endoscopy is widely used for observing, photographing tissue, and taking specimens from lesions and the like. In a conventional method of examining a colon using an endoscope, for example, the endoscope is typically manually inserted into the colon. In this manual technique, patients may often complain of abdominal pain and distention because the colon is extended or excessively dilated, thereby necessitating stopping the endoscopic procedure. Furthermore, it is not unusual for the colon to bleed and be accidentally perforated. Insertion of an endoscope through the sigmoid colon and into the descending colon, or through the splenic flexure, the transverse colon, the hepatic flexure or parts affected by previous operations may also be accompanied with difficulty. Because of these reasons, a colonoscopy is typically performed by a relatively few number of skilled practitioners, and the rate of patient pain and discomfort is high.
US Patent 5,337,732 to Grundfest et al. describes a robot for performing endoscopic procedures, which includes a plurality of segments attached to each other through an articulated joint. Actuators can move the segments together and apart and change their angular orientation to allow the robot to move in an inchworm or snake-like fashion through a cavity or lumen within a patient. Inflatable balloons around the segments inflate to brace a temporarily stationary segment against the lumen walls while other segments move. A compressed gas line attached to the back segment provides compressed gas to inflate the balloons and optionally to drive the actuators. The lead segment includes a television camera and biopsy arm or other sensors and surgical instruments.
SUMMARY OF THE INVENTION
The present invention seeks to provide an improved imaging system which is self- propelled, suitable for imaging body lumens, such as the gastrointestinal (GI) tract. The imaging system of the invention may be sterile and disposable, and may be manufactured at very low cost. The system causes virtually no pain to the patient, being of very low friction and providing maximum comfort and flexibility. The system provides excellent visibility and full movement control.
The imaging system of the present invention may comprise an imaging device assembled on a carrier. First and second outwardly expandable elements may be mounted on the carrier. The second expandable element may be expanded both radially and axially. In one mode of operation, in accordance with an embodiment of the invention, during expansion of the second expandable element, obstruction of the radial expansion of the second expandable element (such as when the second expandable element presses against the inner wall of a body lumen) causes the axial expansion of the second expandable element to propel the carrier and the imaging device axially, as is described more in detail hereinbelow. The imaging system may thus self-propel distally into the body lumen without any need for knowing the local diameter of the body lumen. Other embodiments are also described hereinbelow.
BRIEF DESCRIPTION OF THE DRAWINGS
The present invention will be understood and appreciated more fully from the following detailed description taken in conjunction with the drawings in which:
Fig. 1 A is a simplified pictorial and cut-away illustration of an imaging system, constructed and operative in accordance with an embodiment of the present invention, in a contracted orientation;
Fig. IB is a simplified pictorial illustration of a distal end of the imaging system of Fig. 1A;
Fig. 1C is a simplified sectional illustration of the imaging system of Fig. 1A;
Figs. 1D-1G are simplified pictorial illustrations of the imaging system of Fig. 1 A, showing four steps of a mode of operation thereof, wherein in Fig. ID a proximal expandable element and a distal expandable element are both contracted, in Fig. IE the proximal expandable element expands generally spherically, in Fig. IF the distal and proximal expandable elements are both expanded, and in Fig. 1G the distal expandable element is expanded while the proximal expandable element is contracted;
Fig. 2 is a simplified side-view illustration of the imaging system of Fig. 1A inserted in a body lumen in a contracted orientation, prior to self-propulsion therethrough, in accordance with an embodiment of the present invention; Fig. 3 is a simplified side-view illustration of the imaging system of Fig. 1A with the proximal expandable element partially expanded and not yet touching the inner wall of the body lumen;
Fig. 4 is a simplified side-view illustration of the imaging system of Fig. 1A with the proximal expandable element further expanded and touching the inner wall of the body lumen;
Fig. 5 is a simplified side-view illustration of the imaging system of Fig. 1A with the proximal expandable element further expanded, pressing against the inner wall of the body lumen, and propelling the imaging system distally through the body lumen;
Fig. 6 is a simplified pictorial and cut-away illustration of the imaging system of Fig. 1A in the orientation of Fig. 4 or 5;
Fig. 7 is a simplified pictorial and cut-away illustration of the imaging system of Fig. 1A with the proximal expandable element expanded and a distal expandable element also expanded, in accordance with an embodiment of the present invention;
Fig. 8 is a simplified pictorial and cut-away illustration of the imaging system of Fig. 1A with the proximal expandable element contracted and the distal expandable element expanded, in accordance with an embodiment of the present invention;
Figs. 9 and 10 are simplified pictorial and cut-away illustrations, respectively, of an imaging system, constructed and operative in accordance with another embodiment of the present invention, comprising an expandable element mounted on a carrier;
Figs. 11 and 12 are simplified pictorial and side-view sectional illustrations, respectively, of the imaging system of Figs. 9 and 10, with the expandable element extended distally relative to the carrier;
Fig. 13 is a simplified pictorial illustration of an imaging system, constructed and operative in accordance with another embodiment of the present invention, comprising a jet-action head mounted on a carrier;
Figs. 14-16 are simplified pictorial illustrations of an imaging system, constructed and operative in accordance with yet another embodiment of the present invention, comprising traction members extending from a carrier, wherein in the embodiment illustrated in Fig. 14, the traction members have a helical shape, in Fig. 15, the traction members extend towards a proximal end of the carrier, and in Fig. 16, the traction members extend towards a distal end of the carrier; and
Fig. 17 is a simplified pictorial illustration of an imaging system, constructed and operative in accordance with still another embodiment of the present invention, comprising a percussion device mounted on a carrier.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT
Reference is now made to Fig. 1A, which illustrates an imaging system 10, constructed and operative in accordance with an embodiment of the present invention.
Imaging system 10 may comprise first and second outwardly expandable elements 12 and 14. One of the outwardly expandable elements may be the proximal element and the other one may be the distal element. For example, in terms of the explanation that follows with reference to Figs. 2-8, first element 12 is the distal element that enters the body lumen first, and second element 14 is the proximal element that enters the body lumen last.
In accordance with an embodiment of the present invention, first and second expandable elements 12 and 14 expand to different shapes. First expandable element 12 may expand substantially radially with negligible axial expansion. In contrast, second expandable element 14 may expand both radially and axially, such as expanding generally spherically.
First and second expandable elements 12 and 14 may be mounted coaxially on a carrier 16. Carrier 16 may be made of any suitable, flexible, medically approved material, and may take the form of a tube. The expandable elements 12 and 14 may comprise full circumference or partial circumference elements.
Each expandable element 12 or 14 may comprise an inflatable, elastomeric tubular element formed with annular rings 18. Each expandable element 12 or 14 may be mounted in a pair of collar elements 20, wherein the annular rings 18 are received in annular grooves 22 formed in collar elements 20. Annular ring 18 may be held in groove 22 by means of an annular fastener 21, which snaps together with tongues 19 axially protruding from collar element 20. Collar elements 20 may be formed separately for each expandable element, and may be adjoined together by snapping together or by means of fasteners or any other suitable method. Alternatively, a single collar element 20 may be placed between first and second expandable elements 12 and 14, wherein the single collar element 20 has two sets of annular grooves 22 to receive therein the proximal annular ring 18 of the distal expandable element 12 and the distal annular ring 18 of the proximal expandable element 14. The collar elements 20 may be flexible and resilient to permit passage of imaging system 10 through folds of the GI tract. An O-ring 23 may slidingly seal the most proximal collar element 20 with respect to carrier 16. Accordingly, the collar elements 20 at the ends of first expandable element 12 may be fixed axially with respect to carrier 16, thereby preventing first expandable element 12 from expanding axially. In contrast, second expandable element 14 may slide axially relative to carrier 16.
In accordance with another embodiment of the invention, whether or not the collar elements 20 are fixed axially with respect to carrier 16 may be selectable. In this manner, a user may select which of the expandable elements may expand only radially and which may expand both radially and axially. For example, first expandable element 12 may expand both radially and axially, if desired, instead of second expandable element 14, which may cause imaging system 10 to move in a proximal direction instead of a distal direction.
Carrier 16 may be formed with a distal aperture 24 and a proximal aperture 26. A first supply tube 28 may be introduced through carrier 16 in fluid communication with distal aperture 24. Similarly, a second supply tube 30 may be introduced through earner 16 in fluid communication with proximal aperture 26. First expandable element 12 may be expanded outwards by introducing therein a fluid, such as but not limited to, air or water, by means of first supply tube 28 via distal aperture 24. Likewise, second expandable element 14 may be expanded outwards by introducing therein a fluid (which may or may not be the same fluid used to expand first expandable element 12), by means of second supply tube 30 via proximal aperture 26.
Reference is now made to Figs. IB and lC. An imaging device 32, such as but not limited to, a CCD (charge coupled device) or CMOS (complementary metal oxide semiconductor) camera, may be mounted at a distal end of imaging system 10. For example, imaging device 32 may be mounted in the most distal collar element 20, which may be formed with a viewing window 34 through which images may be captured. Imaging device 32 and viewing window 34 may be oriented for capturing images either axially or radially with respect to carrier 16. A light source 36 may be provided for imaging device 32, wherein electrical wiring and/or optic fibers 38 (Fig. 1C) may be fed through carrier 16 to imaging device 32 and light source 36.
Imaging device 32 may be connected to an imaging processor (not shown) by optical fibers. A control system (not shown) may be provided that oversees and controls the expansion/contraction of the expandable elements 12 and 14, and other functions of imaging system 10, such as but not limited to, the timing and amount of the expansion/contraction of the expandable elements 12 and 14.
Other tubes or passageways may be provided for other functionalities. For example, a suction tube 40 (Fig. IB) may be provided for sucking debris or other material. A tool lumen 42 may be provided for introducing therethrough mechanical devices and/or sensors (not shown), such as but not limited to, cutting devices for cutting and collecting materials for biopsies and the like, and biosensors. Additionally, passageways 44 may be provided for passing therethrough control wires 46 for directing the imaging system 10 through tight bends and the like.
A guide member 50 (Fig. 1C) may be disposed at the proximal end of carrier 16. Guide member 50 may be funnel-shaped, for example, for comfortable placement in a rectum of a patient (not shown). A linear encoder 52 may be disposed at the proximal end of carrier 16 and pass through guide member 50. Linear encoder 52 may comprise markings and the like detectable by a decoder 54 mounted on guide member 50. Decoder 54 may sense linear movement of carrier 16 with respect to linear encoder 52, which movement is described in greater detail hereinbelow.
It is noted that the electrical and optical components may be self-contained in imaging system 10, so that the entire system 10 is fully independent of external wiring. In such an embodiment, imaging system 10 may wirelessly transmit or receive data to or from an external processor (not shown).
Reference is now made to Figs. 1D-1G and Figs. 2-5, which illustrate imaging system 10 in different orientations for self-propulsion through a body lumen 60, such as but not limited to, the colon, in accordance with an embodiment of the present invention. (The body lumen 60 is omitted in Figs. 1D-1G for clarity.)
In the initial orientation of Figs. ID and 2, none of the expandable elements 12 and 14 are expanded, as in Fig. 1 A. In this contracted orientation, imaging system 10 may be inserted in body lumen 60. In Fig. 3, second (proximal) expandable element 14 may be expanded outwardly. As seen in Fig. 3, before the proximal expandable element 14 touches the inner wall of body lumen 60, it may expand both radially and axially (e.g., spherically). O-ring 23 slides proximally along carrier 16, as indicated by arrow 53, with the result that carrier 16 (along with imaging device 32) does not yet advance in body lumen 60.
In Fig. 4, the proximal expandable element 14 has expanded sufficiently so that it touches the inner wall of body lumen 60. Carrier 16 (along with imaging device 32) has still not advanced in body lumen 60, and O-ring 23 has continued to slide proximally along carrier 16, as indicated by arrow 53. The orientation of Fig. 4 is shown in pictorially in Fig. 6. In Fig. 5, the proximal expandable element 14 continues to expand. Since the proximal expandable element 14 has already contacted the inner wall of body lumen 60, the continued expansion of expandable element 14 presses it against the inner wall of body lumen 60. The friction between expandable element 14 and the inner wall resists the radial expansion, with the result that most of the expansion of the proximal expandable element 14 is in the axial direction, as indicated by double arrow 57. This causes carrier
16 (along with imaging device 32) to advance distally in body lumen 60, as indicated by arrow 62, by a distance δ in Fig. 5. The distal advancement of carrier 16 relative to guide member 50 may be detected by linear encoder 52 and decoder 54 (seen also in Fig. IE).
Thus the expansion of second expandable element 14 may advance the carrier 16 distally in body lumen 60, without any need for sensing when second expandable element 14 has actually contacted the inner wall of body lumen 60. Rather once second expandable element 14 presses against the inner wall of body lumen 60, further expansion of second expandable element 14 may advance the carrier 16 distally in body lumen 60. The control system may control the further expansion of second expandable element 14 in order to control the amount of incremental advancement of carrier 16 and imaging device 32.
In Figs. IF and 7, first (distal) expandable element 12 may be expanded radially. Both first and second expandable elements 12 and 14 now press against the inner wall of body lumen 60 (not shown in Fig. 7) and fix imaging system 10 in place in lumen 60. In Figs. 1G and 8, second expandable element 14 may be contracted inwardly (e.g., deflated) so that it no longer presses against the inner wall of body lumen 60 (not shown in Fig. 8). Images may be captured by imaging device 32 at either of the orientations shown in Figs. 7 and 8. As seen best in Fig. 1G, second expandable element 14 advances distally along carrier 16 when it is contracted inwardly, as indicated by arrow 67.
In order to advance carrier 16 further distally, first expandable element 12 may be contracted so that imaging system 10 returns to the contracted orientation of Fig. 2, and the operating cycle may be repeated to incrementally advance imaging system 10 through body lumen 60. The user or control system may ensure that carrier 16 does not move back proximally at each increment distal advance. Alternatively, as another way of ensuring that carrier 16 does not move back proximally at each incremental distal advance, first expandable element 12 may initially remain expanded against the inner wall of body lumen 60 while re-expanding second expandable element 14, and then first expandable element 12 may be contracted so as not to impede the incremental distal advancement caused by the re-expansion of second expandable element 14. The control system may control the timing of the contraction of the first expandable element 12 and the expansion of the second expandable element 14.
Imaging system 10 may be contracted to the orientation of Fig. 2 for removal from body lumen 60.
Reference is now made to Figs. 9-12, which illustrate an imaging system 70, constructed and operative in accordance with an embodiment of the present invention.
Imaging system 70 may comprise a carrier 72, such as in the form of a tube, to which a stopper 74 is mounted at a distal portion thereof. An expandable element 82 may be at a distal portion of carrier 72 in fluid communication with a fluid source (not shown) via one or more apertures 80. Expandable element 82 and carrier 72 may comprise an elastic, flexible member folded into itself, wherein the expandable element 82 is at the distal end and the carrier 72 extends proximally therefrom. An O-ring 78 may seal expandable element 82 with respect to the rest of carrier 72 (Fig. 12). Fluid 79 may flow through aperture 80 to at least partially fill expandable element 82 (Fig. 12). Expandable element 82 may comprise a flexible sleeve, such as a sleeve made of an elastomeric material (e.g., rubber, latex, etc.).
Imaging system 70 may be inserted in a body lumen, e.g., rectum of a patient (not shown), wherein stopper 74 abuts against the anus (not shown). Fluid 79 may then be introduced via aperture 80 to at least partially fill the flexible sleeve, thereby expanding expandable element 82 relative to carrier 72 and further into the colon (not shown). The portion of carrier 72 proximal to stopper 74 may be drawn distally into the colon by the expansion of expandable element 82. Carrier 72 may have a lumen 76 for passage therethrough of an instrument 84, such as but not limited to, imaging devices (e.g., camera, x-ray imaging device), illumination devices, biopsy collecting tools, optical devices, fluid devices, etc. The instrument 84 may pass all the way through lumen 76 and through a distal aperture 73. In this manner, for example, an imaging device may be introduced through carrier 72 to provide images of the colon.
Reference is now made to Fig. 13, which illustrates an imaging system 90, constructed and operative in accordance with another embodiment of the present invention.
Imaging system 90 may comprise a carrier 92, such as in the form of a tube, comprising a fluid passageway 93 for passage of a fluid 94 (liquid or gas) therethrough. A jet-action head 95 may be mounted on a distal end 91 of carrier 92. Jet-action head 95 may be formed with fluid jet outlets 96 facing a proximal end of carrier 92, which are in fluid communication with fluid passageway 93. An imaging device 97 may be disposed in jet-action head 95. As mentioned similarly above, imaging device 97 may comprise, without limitation, illumination devices, biopsy devices, other tools, etc. Imaging device
97 may comprise a camera, in which case jet-action head 95 is preferably transparent.
Imaging device 97 may alternatively comprise an x-ray imaging device, for example.
Imaging system 90 may be inserted in a rectum of a patient (not shown), and fluid 94 introduced in fluid passageway 93 (from a fluid source, not shown) exits fluid jet outlets 96 to propel imaging system 90 in the body lumen, e.g., colon (not shown).
Jet-action head 95 may be expandable and contractible, such as made of an elastomeric material. Alternatively, jet-action head 95 may be made of a rigid material, such as but not limited to, plastic or metal. Jet-action head 95 may comprise a magnet 98 for attaching to an imaging device (capsule or bolus) in the gastrointestinal tract (not shown). Any of the other embodiments of the present invention may also comprise a magnet like magnet 98.
Reference is now made to Figs. 14-16, which illustrate an imaging system 100, constructed and operative in accordance with another embodiment of the present invention. Imaging system 100 may comprise a carrier 102, such as in the form of a tube, which comprises one or more traction members 104. Traction member 104 may comprise a loop 106 extending from carrier 102. An actuator 108 may be in operative communication with traction member 104. Actuator 108 may comprise, without limitation, a servomotor, gear motor, step motor and the like.
In the embodiment illustrated in Fig. 14, loop 106 may have a helical shape that at least partially corkscrews around a periphery of carrier 102. In the embodiment illustrated in Fig. 15, loop 106 protrudes from a side of carrier 102 and extends towards a proximal end 109 of carrier 102. In the embodiment illustrated in Fig. 16, loop 106 protrudes from a side of carrier 102 and extends towards a distal end 111 of carrier 102. It is appreciated that these are just some examples of possible loops and the invention is not limited to these examples. The traction members 104 may be provided in any amount, size and shape.
Actuator 108 may move loop 106 relative to carrier 102. For example, in the illustrated embodiments, loop 106 may be rotated about its own axis (as indicated by arrows 112). Alternatively, as indicated by arrows 114 in Figs. 15 and 16, loops 106 may be rotated like the track of a tracked vehicle. The rotational movement of loops 106 against the inner wall of the body lumen, e.g., colon (not shown), propels and advances imaging system 100 through the colon. To increase traction and friction against the lumen walls, loop 106 may be expandable and contractible, such as by means of a fluid introduced therein through appropriate fluid passageways (not shown) in carrier 102, as similarly described hereinabove for the embodiment of Figs. 9-12. The expansion of loop
106 may improve the field of view for imaging. It is noted that in any of the embodiments of the invention, components may be inflated to improve the view for imaging.
An imaging device 116 (seen in the embodiment of Fig. 16) may be disposed in carrier 102. Imaging device 116 may comprise a camera, in which case the distal end of carrier 102 is preferably transparent. Imaging device 116 may alternatively comprise an x-ray imaging device.
It is noted that in any of the embodiments of the invention, the components of the system may be energized by an internal or external power source, and may comprise a transmitter and/ or receiver to an external device. It is further noted that in any of the embodiments of the invention, the elements that move in the body lumen may be shaped or may comprise structure that preferentially facilitate movement in one direction (e.g., in the distal direction) as opposed to the opposite direction (e.g., in the proximal direction). Such structure may comprise, without limitation, inflatable protrusions or spurs, which when deflated or contracted, permit movement in the opposite direction (e.g., in the proximal direction).
Reference is now made to Fig. 17, which illustrates an imaging system 120, constructed and operative in accordance with another embodiment of the present invention.
Imaging system 120 may comprise a carrier 122, such as in the form of a tube. A percussion device 124 may be mounted on a distal portion of carrier 122. Percussion device 124 may comprise, without limitation, a vibrator, an oscillator, a solenoid device, a pneumatic, hydraulic, or electromechanical hammering device and the like. Percussion device 124 may contain its own power source (e.g., battery) or may be operated by an external actuator (not shown). Oscillation or vibration of percussion device 124, indicated by arrows 126, against the inner wall of the body lumen, e.g., colon (not shown), propels and advances imaging system 120 through the colon. An imaging device 128 may be disposed in the distal portion of carrier 122. Imaging device 128 may comprise a camera, in which case the distal end of carrier 122 is preferably transparent. Imaging device 128 may alternatively comprise an x-ray imaging device. In the embodiment of Fig. 17, it is possible to use carrier 122 as a guide member or wire for a catheter-like procedure (as similarly used in angioplasty procedures), wherein an instrument may be introduced in or over carrier 122. For example, an outer catheter 129 may be slipped over carrier 122. An instrument 127 may be introduced over carrier 122, on either side of percussion device 124, and may be pushed distally by any suitable means. As similarly described hereinabove with instrument 84, the instrument
127 that may be introduced in or over carrier 122 may comprise, without limitation, a torus-shaped camera (CCD) or other imaging device (e.g., x-ray imaging device), illumination device, biopsy collecting tool, optical device, fluid device, etc.
It will be appreciated by person skilled in the art that the present invention is not limited by what has been particularly shown and described herein above. Rather the scope of the present invention is defined only by the claims that follow:

Claims

CLAIMSWhat is claimed is:
1. An imaging system comprising: an imaging device assembled on a carrier; and a first outwardly expandable element and a second outwardly expandable element mounted on said carrier, wherein said second expandable element is expandable both radially and axially, said imaging system comprising a mode of operation, wherein during expansion of said second expandable element, obstruction of the radial expansion of said second expandable element causes the axial expansion of said second expandable element to propel said carrier and said imaging device axially.
2. The imaging system according to claim 1, wherein said first expandable element is fixed axially to said carrier, and said second expandable element is slidable axially relative to said carrier.
3. The imaging system according to claim 1, wherein said carrier is formed with first and second apertures in fluid communication with said first and second expandable elements, respectively.
4. The imaging system according to claim 3, further comprising a first supply tube disposed in said carrier in fluid communication with said first aperture, and a second supply tube disposed in said carrier in fluid communication with said second aperture.
5. The imaging system according to claim 1, wherein said first and second expandable elements are expandable to different shapes.
6. The imaging system according to claim 1, wherein said first expandable element is expandable substantially radially with negligible axial expansion.
7. The imaging system according to claim 1, wherein said second expandable element is expandable generally spherically.
8. The imaging system according to claim 1, wherein said imaging device is mounted at a distal end of said carrier, distally of said first and second expandable elements.
9. The imaging system according to claim 1, further comprising a light source disposed in said carrier.
10. The imaging system according to claim 1, further comprising a suction tube disposed in said carrier.
11. The imaging system according to claim 1, further comprising a tool lumen disposed in said carrier.
12. The imaging system according to claim 1, further comprising control wires disposed in said carrier.
13. The imaging system according to claim 1, further comprising a guide member disposed at a proximal end of said carrier.
14. The imaging system according to claim 1, further comprising a linear encoder disposed on said carrier, and a decoder operative to sense linear movement of said carrier with respect to said linear encoder.
15. An imaging system comprising : a carrier comprising a fluid passageway; an expandable element mounted on a distal portion of said carrier and in fluid communication with said fluid passageway, said expandable element comprising a flexible sleeve, wherein in a first orientation, said flexible sleeve is folded into itself, and in a second orientation fluid at least partially fills said flexible sleeve and at least partially unfolds said flexible sleeve, so as to extend said expandable element distally outwards from said carrier; and an imaging device disposed in said expandable element.
16. An imaging system comprising: a carrier comprising a fluid passageway; a jet-action head mounted on a distal end of said carrier, said jet-action head being formed with fluid jet outlets facing a proximal end of said carrier, which are in fluid communication with said fluid passageway; and an imaging device disposed in said jet-action head, wherein fluid expelled from said fluid jet outlets propels said imaging system.
17. The imaging system according to claim 16, wherein said jet-action head is expandable and contractible.
18. An imaging system comprising : a carrier; at least one traction member comprising a loop extending from said carrier; and an actuator in operative communication with said at least one traction member, said actuator moving said loop relative to said carrier.
19. The imaging system according to claim 18, wherein said loop has a helical shape that at least partially corkscrews around a periphery of said carrier.
20. The imaging system according to claim 18, wherein said loop protrudes from a side of said carrier and extends towards a proximal end of said carrier.
21. The imaging system according to claim 18, wherein said loop protrudes from a side of said carrier and extends towards a distal end of said carrier.
22. The imaging system according to claim 18, wherein said loop is expandable and contractible.
23. The imaging system according to claim 18, further comprising an imaging device disposed in said carrier.
24. An imaging system comprising: a carrier; a percussion device mounted on a distal portion of said carrier; and an imaging device mounted on the distal portion of said carrier.
25. The imaging system according to claim 24, wherein said carrier comprises a guide member for a catheter-like procedure.
26. The imaging system according to any of the preceding claims, further comprising a magnet adapted to be attached to an object in a gastrointestinal tract.
PCT/IL2003/000627 2001-07-02 2003-07-29 Self-propelled imaging system WO2004010858A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2004524045A JP4541888B2 (en) 2002-07-29 2003-07-29 Self-propelled image system
US10/523,578 US20060201351A1 (en) 2001-07-02 2003-07-29 Self-propelled imaging system
EP03741050A EP1526802A2 (en) 2002-07-29 2003-07-29 Self-propelled imaging system
AU2003281767A AU2003281767A1 (en) 2002-07-29 2003-07-29 Self-propelled imaging system

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US39883802P 2002-07-29 2002-07-29
US60/398,838 2002-07-29
US10/302,897 2002-11-25
US10/302,897 US6988986B2 (en) 2002-11-25 2002-11-25 Self-propelled imaging system

Publications (2)

Publication Number Publication Date
WO2004010858A2 true WO2004010858A2 (en) 2004-02-05
WO2004010858A3 WO2004010858A3 (en) 2004-03-25

Family

ID=31190813

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2003/000627 WO2004010858A2 (en) 2001-07-02 2003-07-29 Self-propelled imaging system

Country Status (4)

Country Link
EP (1) EP1526802A2 (en)
JP (1) JP4541888B2 (en)
AU (1) AU2003281767A1 (en)
WO (1) WO2004010858A2 (en)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7087011B2 (en) 2003-12-30 2006-08-08 Gi View Ltd. Gastrointestinal system with traction member
JP2006334141A (en) * 2005-06-02 2006-12-14 Konica Minolta Medical & Graphic Inc Capsule endoscope
WO2006072928A3 (en) * 2005-01-06 2007-05-18 G I View Ltd Gastrointestinal tool over guiding element
JP2008531193A (en) * 2005-02-28 2008-08-14 ユニヴァーシティ オブ ワシントン Capsule endoscope with tether for Barrett's esophageal screening
WO2008125529A1 (en) * 2007-04-13 2008-10-23 Siemens Aktiengesellschaft Navigable endoscopy capsule
WO2008155776A1 (en) 2007-06-21 2008-12-24 Easyglide Ltd. System for advancing in a body lumen
US20090182197A1 (en) * 2005-08-01 2009-07-16 G.I. View Ltd. Tools for use in small intestine
ES2341086A1 (en) * 2010-01-29 2010-06-14 Nicolas Anthony Costovici Catheter for performing image-based colonoscopies
GB2466985A (en) * 2009-01-19 2010-07-21 Univ Sheffield Hallam A self-retaining speculum
US7947013B2 (en) 2004-01-09 2011-05-24 G.I. View Ltd. Pressure-propelled system for body lumen
US8419678B2 (en) 2004-01-09 2013-04-16 G.I. View Ltd. Pressure-propelled system for body lumen
US8702620B2 (en) 2008-11-03 2014-04-22 G.I. View Ltd. Remote pressure sensing system and method thereof
US8876730B2 (en) 2007-01-17 2014-11-04 G. I. View Ltd. Diagnostic or treatment tool for colonoscopy
US9597179B2 (en) 2011-07-25 2017-03-21 Rainbow Medical Ltd. Sinus stent
US10080481B2 (en) 2005-02-10 2018-09-25 G.I. View Ltd. Advancement techniques for gastrointestinal tool with guiding element
US10226600B2 (en) 2008-07-30 2019-03-12 G.I. View Ltd. System and method for enhanced maneuverability
US10441144B2 (en) 2013-08-31 2019-10-15 Mor Research Applications Ltd. Endoscope with shared working channel

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9241614B2 (en) 2005-08-01 2016-01-26 G.I. View Ltd. Tools for use in esophagus
US8430809B2 (en) 2005-08-01 2013-04-30 G. I View Ltd. Capsule for use in small intestine
US20080015413A1 (en) * 2006-02-22 2008-01-17 Olympus Medical Systems Corporation Capsule endoscope system and medical procedure
JP5307338B2 (en) * 2007-02-05 2013-10-02 オリンパス株式会社 Endoscope device
JP5331318B2 (en) * 2007-08-09 2013-10-30 オリンパス株式会社 Endoscope device
JP2012183221A (en) * 2011-03-07 2012-09-27 Fujifilm Corp Self-propelled device

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5337732A (en) 1992-09-16 1994-08-16 Cedars-Sinai Medical Center Robotic endoscopy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1465723A (en) * 1965-12-03 1967-01-13 Alsthom Cgee Probe capable of moving in a tube without taking support from the outside
JPS5431825Y2 (en) * 1975-06-30 1979-10-04
US4561427A (en) * 1983-01-05 1985-12-31 Masazumi Takada Endoscope
DE3635183A1 (en) * 1986-10-16 1988-04-28 Medizintechnik Wedel Gmbh & Co Mobile intestinal probe
US4838859A (en) * 1987-05-19 1989-06-13 Steve Strassmann Steerable catheter
JPH07313443A (en) * 1994-05-23 1995-12-05 Olympus Optical Co Ltd Inserting device of in-pipe inserting implement
US6007482A (en) * 1996-12-20 1999-12-28 Madni; Asad M. Endoscope with stretchable flexible sheath covering
AUPP123698A0 (en) * 1998-01-07 1998-01-29 Ayre, Peter Self propelling endoscope
JPH11342106A (en) * 1998-06-03 1999-12-14 Masazumi Takada Self-traveling colon endoscope

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5337732A (en) 1992-09-16 1994-08-16 Cedars-Sinai Medical Center Robotic endoscopy

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8602974B2 (en) 2003-08-13 2013-12-10 G.I. View Ltd. Gastrointestinal tool over guiding element
US7087011B2 (en) 2003-12-30 2006-08-08 Gi View Ltd. Gastrointestinal system with traction member
US8419678B2 (en) 2004-01-09 2013-04-16 G.I. View Ltd. Pressure-propelled system for body lumen
US7947013B2 (en) 2004-01-09 2011-05-24 G.I. View Ltd. Pressure-propelled system for body lumen
EP2361545A1 (en) 2005-01-06 2011-08-31 G.I. View Ltd. Gastrointestinal tool over guiding element
WO2006072928A3 (en) * 2005-01-06 2007-05-18 G I View Ltd Gastrointestinal tool over guiding element
AU2005323771B2 (en) * 2005-01-06 2011-03-31 G.I. View Ltd. Gastrointestinal tool over guiding element
US10080481B2 (en) 2005-02-10 2018-09-25 G.I. View Ltd. Advancement techniques for gastrointestinal tool with guiding element
JP2008531193A (en) * 2005-02-28 2008-08-14 ユニヴァーシティ オブ ワシントン Capsule endoscope with tether for Barrett's esophageal screening
US9161684B2 (en) 2005-02-28 2015-10-20 University Of Washington Monitoring disposition of tethered capsule endoscope in esophagus
US9872613B2 (en) 2005-02-28 2018-01-23 University Of Washington Monitoring disposition of tethered capsule endoscope in esophagus
JP2013240712A (en) * 2005-02-28 2013-12-05 Univ Of Washington Tethered capsule endoscope for barrett's esophagus screening
JP2006334141A (en) * 2005-06-02 2006-12-14 Konica Minolta Medical & Graphic Inc Capsule endoscope
US20090182197A1 (en) * 2005-08-01 2009-07-16 G.I. View Ltd. Tools for use in small intestine
US8876730B2 (en) 2007-01-17 2014-11-04 G. I. View Ltd. Diagnostic or treatment tool for colonoscopy
WO2008125529A1 (en) * 2007-04-13 2008-10-23 Siemens Aktiengesellschaft Navigable endoscopy capsule
WO2008155776A1 (en) 2007-06-21 2008-12-24 Easyglide Ltd. System for advancing in a body lumen
US10226600B2 (en) 2008-07-30 2019-03-12 G.I. View Ltd. System and method for enhanced maneuverability
US8702620B2 (en) 2008-11-03 2014-04-22 G.I. View Ltd. Remote pressure sensing system and method thereof
GB2466985B (en) * 2009-01-19 2011-04-27 Univ Sheffield Hallam A speculum
GB2466985A (en) * 2009-01-19 2010-07-21 Univ Sheffield Hallam A self-retaining speculum
WO2011092358A1 (en) * 2010-01-29 2011-08-04 Nicolas Anthony Costovici Catheter for performing image-based colonoscopies
ES2341086A1 (en) * 2010-01-29 2010-06-14 Nicolas Anthony Costovici Catheter for performing image-based colonoscopies
US9597179B2 (en) 2011-07-25 2017-03-21 Rainbow Medical Ltd. Sinus stent
US10441144B2 (en) 2013-08-31 2019-10-15 Mor Research Applications Ltd. Endoscope with shared working channel

Also Published As

Publication number Publication date
WO2004010858A3 (en) 2004-03-25
EP1526802A2 (en) 2005-05-04
AU2003281767A1 (en) 2004-02-16
JP4541888B2 (en) 2010-09-08
JP2005534367A (en) 2005-11-17

Similar Documents

Publication Publication Date Title
US6988986B2 (en) Self-propelled imaging system
JP4541888B2 (en) Self-propelled image system
JP5341315B2 (en) Pressure propulsion system for body lumen
JP5658289B2 (en) Pressure propulsion system for body lumen
US10363396B2 (en) Biological navigation device
US6007482A (en) Endoscope with stretchable flexible sheath covering
US7635345B2 (en) Pressure-propelled system for body lumen
US6485409B1 (en) Propulsion of a probe in the colon using a flexible sleeve
US8419678B2 (en) Pressure-propelled system for body lumen
US7833176B2 (en) Pressure-propelled system for body lumen
US20230079408A1 (en) Devices and systems for body cavities and methods of use
US20240041301A1 (en) Body cavity navigation devices and methods of use
KR101105218B1 (en) Pressure-propelled system for body lumen
IL176610A (en) Pressure-propelled system for body lumen
IL212934A (en) Pressure-propelled system for body lumen

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2004524045

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2003741050

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2003741050

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 10523578

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 10523578

Country of ref document: US