WO2004065564A3 - Electromagnetic activation of gene expression and cell growth - Google Patents

Electromagnetic activation of gene expression and cell growth Download PDF

Info

Publication number
WO2004065564A3
WO2004065564A3 PCT/US2004/001694 US2004001694W WO2004065564A3 WO 2004065564 A3 WO2004065564 A3 WO 2004065564A3 US 2004001694 W US2004001694 W US 2004001694W WO 2004065564 A3 WO2004065564 A3 WO 2004065564A3
Authority
WO
WIPO (PCT)
Prior art keywords
activating
cell
gene expression
cell growth
delivering
Prior art date
Application number
PCT/US2004/001694
Other languages
French (fr)
Other versions
WO2004065564A2 (en
Inventor
Frank R George
John Moffett
Original Assignee
Regenesis Biomedical Inc
Frank R George
John Moffett
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regenesis Biomedical Inc, Frank R George, John Moffett filed Critical Regenesis Biomedical Inc
Priority to CA002514210A priority Critical patent/CA2514210A1/en
Priority to EP04704094A priority patent/EP1592790A4/en
Priority to AU2004205915A priority patent/AU2004205915A1/en
Publication of WO2004065564A2 publication Critical patent/WO2004065564A2/en
Publication of WO2004065564A3 publication Critical patent/WO2004065564A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2529/00Culture process characterised by the use of electromagnetic stimulation

Abstract

The invention is directed to a method for accelerating the cell cycle by delivering to a cell an effective amount of electromagnetic energy. The invention also provides a method for activating a cell cycle regulator by delivering to a cell an effective amount of electromagnetic energy. Also provided by the invention is a method for activating a signal transduction protein; a method for activating a transcription factor; a method for activating a DNA synthesis protein; and a method for activating a Receptor. A method for inhibiting an angiotensin receptor as well as a method for reducing inflammation also are provided by the present invention. The invention also is directed to a method for replacing damaged neuronal tissue as well as a method for stimulating growth of administered cells.
PCT/US2004/001694 2003-01-22 2004-01-21 Electromagnetic activation of gene expression and cell growth WO2004065564A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002514210A CA2514210A1 (en) 2003-01-22 2004-01-21 Electromagnetic activation of gene expression and cell growth
EP04704094A EP1592790A4 (en) 2003-01-22 2004-01-21 Electromagnetic activation of gene expression and cell growth
AU2004205915A AU2004205915A1 (en) 2003-01-22 2004-01-21 Electromagnetic activation of gene expression and cell growth

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US50906103P 2003-01-22 2003-01-22
US35031303A 2003-01-22 2003-01-22
US10/350,313 2003-01-22
US10/759,526 US20050059153A1 (en) 2003-01-22 2004-01-16 Electromagnetic activation of gene expression and cell growth

Publications (2)

Publication Number Publication Date
WO2004065564A2 WO2004065564A2 (en) 2004-08-05
WO2004065564A3 true WO2004065564A3 (en) 2005-02-03

Family

ID=38434624

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/001694 WO2004065564A2 (en) 2003-01-22 2004-01-21 Electromagnetic activation of gene expression and cell growth

Country Status (5)

Country Link
US (1) US20050059153A1 (en)
EP (1) EP1592790A4 (en)
AU (2) AU2004205915A1 (en)
CA (1) CA2514210A1 (en)
WO (1) WO2004065564A2 (en)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7837719B2 (en) 2002-05-09 2010-11-23 Daemen College Electrical stimulation unit and waterbath system
US20040057983A1 (en) 2002-09-25 2004-03-25 David Schmidt Biomolecular wearable apparatus
US7094572B2 (en) * 2003-03-14 2006-08-22 Bristol-Myers Squibb Polynucleotide encoding a novel human G-protein coupled receptor variant of HM74, HGPRBMY74
US20040226556A1 (en) * 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
US9433797B2 (en) 2003-12-05 2016-09-06 Rio Grande Neurosciences, Inc. Apparatus and method for electromagnetic treatment of neurodegenerative conditions
US20110112352A1 (en) * 2003-12-05 2011-05-12 Pilla Arthur A Apparatus and method for electromagnetic treatment
US20070173904A1 (en) * 2006-01-25 2007-07-26 Pilla Arthur A Self-contained electromagnetic apparatus for treatment of molecules, cells, tissues, and organs within a cerebrofacial area and method for using same
US20130218235A9 (en) * 2005-03-07 2013-08-22 Arthur A. Pilla Excessive fibrous capsule formation and capsular contracture apparatus and method for using same
US9440089B2 (en) 2003-12-05 2016-09-13 Rio Grande Neurosciences, Inc. Apparatus and method for electromagnetic treatment of neurological injury or condition caused by a stroke
US7744524B2 (en) * 2003-12-05 2010-06-29 Ivivi Health Sciences, Llc Apparatus and method for electromagnetic treatment of plant, animal, and human tissue, organs, cells, and molecules
US8961385B2 (en) * 2003-12-05 2015-02-24 Ivivi Health Sciences, Llc Devices and method for treatment of degenerative joint diseases with electromagnetic fields
US9656096B2 (en) 2003-12-05 2017-05-23 Rio Grande Neurosciences, Inc. Method and apparatus for electromagnetic enhancement of biochemical signaling pathways for therapeutics and prophylaxis in plants, animals and humans
US10350428B2 (en) 2014-11-04 2019-07-16 Endonovo Therapetics, Inc. Method and apparatus for electromagnetic treatment of living systems
US9415233B2 (en) 2003-12-05 2016-08-16 Rio Grande Neurosciences, Inc. Apparatus and method for electromagnetic treatment of neurological pain
US7840263B2 (en) * 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
CA2563660C (en) 2004-04-19 2012-10-30 Ivivi Technologies, Inc. Electromagnetic treatment apparatus and method
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7729761B2 (en) * 2004-07-14 2010-06-01 Cardiac Pacemakers, Inc. Method and apparatus for controlled gene or protein delivery
JP2008507995A (en) * 2004-08-02 2008-03-21 セルーメン、インコーポレイテッド Method for detecting molecular interactions in cells
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US8060219B2 (en) 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US20070036770A1 (en) * 2005-08-12 2007-02-15 Wagner Darrell O Biologic device for regulation of gene expression and method therefor
US8457324B2 (en) * 2005-08-16 2013-06-04 Honeywell International Inc. Directional speaker system
US7774057B2 (en) 2005-09-06 2010-08-10 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression for cardiac protection
US9037247B2 (en) 2005-11-10 2015-05-19 ElectroCore, LLC Non-invasive treatment of bronchial constriction
CN101674862A (en) * 2005-11-10 2010-03-17 电子核心公司 Electrical stimulation treatment of bronchial constriction
US8812112B2 (en) * 2005-11-10 2014-08-19 ElectroCore, LLC Electrical treatment of bronchial constriction
US8041428B2 (en) 2006-02-10 2011-10-18 Electrocore Llc Electrical stimulation treatment of hypotension
US20110125203A1 (en) * 2009-03-20 2011-05-26 ElectroCore, LLC. Magnetic Stimulation Devices and Methods of Therapy
EP1984065B1 (en) 2006-02-10 2012-08-22 Electrocore, Inc. Electrical stimulation treatment of hypotension
AU2006337679A1 (en) * 2006-02-10 2007-08-16 Electrocore, Inc. Methods and apparatus for treating anaphylaxis using electrical modulation
US20100241188A1 (en) * 2009-03-20 2010-09-23 Electrocore, Inc. Percutaneous Electrical Treatment Of Tissue
JP5406019B2 (en) 2006-05-17 2014-02-05 セルーメン、インコーポレイテッド Method for automated tissue analysis
WO2008060483A2 (en) * 2006-11-10 2008-05-22 Cellumen, Inc. Protein-protein interaction biosensors and methods of use thereof
US20090005713A1 (en) * 2007-02-12 2009-01-01 Podrazhansky Yury M Method and Device for Using Vibroacoustical Stimulation to Treat Target Tissue Areas of Living Organisms
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
EP2259774B1 (en) 2008-02-27 2012-12-12 Biomet Biologics, LLC Methods and compositions for delivering interleukin-1 receptor antagonist
ES2398052T5 (en) 2008-05-09 2021-10-25 Nuvaira Inc Systems for treating a bronchial tree
US8602961B2 (en) 2008-05-15 2013-12-10 Lifewave Products Llc Apparatus and method of stimulating elevation of glutathione levels in a subject
EP2493408B1 (en) 2009-10-27 2015-06-24 Holaira, Inc. Delivery devices with coolable energy emitting assemblies
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
KR101820542B1 (en) 2009-11-11 2018-01-19 호라이라 인코포레이티드 Systems, apparatuses, and methods for treating tissue and controlling stenosis
EP2977054A1 (en) * 2010-09-03 2016-01-27 Biomet Biologics, LLC Methods and compositions for delivering interleukin-1 receptor antagonist
WO2012045079A2 (en) 2010-10-01 2012-04-05 Ivivi Health Sciences, Llc Method and apparatus for electromagnetic treatment of head cerebral and neural injury in animals and humans
WO2012048423A1 (en) * 2010-10-13 2012-04-19 Biolux Research Limited Method and apparatus for tooth regulation with heavy forces
US10018631B2 (en) 2011-03-17 2018-07-10 Cernostics, Inc. Systems and compositions for diagnosing Barrett's esophagus and methods of using the same
US8343027B1 (en) 2012-01-30 2013-01-01 Ivivi Health Sciences, Llc Methods and devices for providing electromagnetic treatment in the presence of a metal-containing implant
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
US9758806B2 (en) 2013-03-15 2017-09-12 Biomet Biologics, Llc Acellular compositions for treating inflammatory disorders
US9878011B2 (en) 2013-03-15 2018-01-30 Biomet Biologics, Llc Treatment of inflammatory respiratory disease using biological solutions
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
WO2015058284A1 (en) 2013-10-22 2015-04-30 Biolux Research Ltd. Intra-oral light-therapy apparatuses and methods for their use
US9320913B2 (en) 2014-04-16 2016-04-26 Rio Grande Neurosciences, Inc. Two-part pulsed electromagnetic field applicator for application of therapeutic energy
US10441807B2 (en) * 2014-11-21 2019-10-15 Regenesis Biomedical, Inc. Treatment of conditions susceptible to pulsed electromagnetic field therapy
US10806942B2 (en) 2016-11-10 2020-10-20 Qoravita LLC System and method for applying a low frequency magnetic field to biological tissues
WO2019023265A1 (en) 2017-07-24 2019-01-31 Regenesis Biomedical, Inc. High-power pulsed electromagnetic field applicator system
US11207541B2 (en) 2018-03-23 2021-12-28 Regenesis Biomedical, Inc. High-power pulsed electromagnetic field applicator systems
US11547848B2 (en) 2018-06-21 2023-01-10 Regenesis Biomedical, Inc. High-power pulsed electromagnetic field applicator systems
CN109529192A (en) * 2018-11-15 2019-03-29 郭良 One kind activating the active device and method of ERK by applying AC field
US11833363B2 (en) 2019-10-25 2023-12-05 Regenesis Biomedical, Inc. Current-based RF driver for pulsed electromagnetic field applicator systems

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6334069B1 (en) * 1998-01-15 2001-12-25 Regenesis Biomedical, Inc. Pulsed electromagnetic energy treatment apparatus and method
US20020177885A1 (en) * 2000-10-24 2002-11-28 Eisfeld Timothy M. Method and device for selectively targeting cells within a three-dimensional specimen
US20040014052A1 (en) * 2002-07-22 2004-01-22 Kurtz Warren H. Process for regulating gene expression

Family Cites Families (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3181535A (en) * 1957-10-04 1965-05-04 Diapulse Mfg Corp Of America Athermapeutic apparatus
US3043310A (en) * 1959-04-24 1962-07-10 Diapulse Mfg Corp Of America Treatment head for athermapeutic apparatus
US3127895A (en) * 1962-07-02 1964-04-07 Dynapower System Corp Therapeutic pulse generation and control circuit
US3229892A (en) * 1962-07-16 1966-01-18 Continental Can Co Carrier for single chime cans
US3329148A (en) * 1965-09-21 1967-07-04 Dynapower Systems Corp Of Cali Control of electrotherapeutic apparatus
US3978864A (en) * 1965-10-11 1976-09-07 L. B. Smith Estates, Inc. Electrotherapeutic treatment head
US3513851A (en) * 1966-07-19 1970-05-26 W F L Try Electrotherapeutic pulse generating apparatus
US3464010A (en) * 1966-10-25 1969-08-26 Diapulse Corp Of America Power meter for athermapeutic apparatus
US3503403A (en) * 1967-04-27 1970-03-31 Medical Electronics Corp Power supply
US3566877A (en) * 1968-01-05 1971-03-02 Luther B Smith Electrotherapeutic apparatus and treatment head and method for tuning said treatment head
US3638657A (en) * 1969-07-30 1972-02-01 Hal C Mettler Short wave diathermy circuit
US3670737A (en) * 1970-07-02 1972-06-20 Diapulse Corp Of America Ultra-short wave athermapeutic apparatus
AT316729B (en) * 1971-04-06 1974-07-25 Kraus Werner Device to support the formation of bone substance
US3800802A (en) * 1972-01-07 1974-04-02 Int Medical Electronics Ltd Short-wave therapy apparatus
US3893462A (en) * 1972-01-28 1975-07-08 Esb Inc Bioelectrochemical regenerator and stimulator devices and methods for applying electrical energy to cells and/or tissue in a living body
DE2314573C2 (en) * 1973-03-23 1986-12-18 Werner Dipl.-Ing. 8000 München Kraus Device for promoting healing processes
JPS6025138B2 (en) * 1973-12-28 1985-06-17 宏 佐藤 Audio frequency band AC electric therapy device
LU70345A1 (en) * 1974-06-18 1976-05-31
DE7422801U (en) * 1974-07-04 1977-04-07 Kraus, Werner, Dipl.-Ing., 8000 Muenchen Solenoil coil for an electromagnetic therapy device
US3952751A (en) * 1975-01-08 1976-04-27 W. Denis Kendall High-performance electrotherapeutic apparatus
US4266532A (en) * 1976-11-17 1981-05-12 Electro-Biology, Inc. Modification of the growth, repair and maintenance behavior of living tissues and cells by a specific and selective change in electrical environment
US4197851A (en) * 1977-04-14 1980-04-15 Fellus Victor M Apparatus for emitting high-frequency electromagnetic waves
CH617590A5 (en) * 1977-05-27 1980-06-13 Carba Ag
JPS54119792A (en) * 1978-03-03 1979-09-17 Iriyou Kougaku Kenkiyuushiyo K Electric stimulation device for removing pain
US4210152A (en) * 1978-05-01 1980-07-01 International Medical Electronics Ltd. Method and apparatus for measuring and controlling the output power of a shortwave therapy apparatus
US4429698A (en) * 1979-09-13 1984-02-07 Bentall Richard Hugh Cameron High frequency electromagnetic therapy apparatus
DE2939254A1 (en) * 1979-09-27 1981-04-09 Siemens AG, 1000 Berlin und 8000 München HEART PACEMAKER
US4323056A (en) * 1980-05-19 1982-04-06 Corning Glass Works Radio frequency induced hyperthermia for tumor therapy
US4587957A (en) * 1981-08-20 1986-05-13 Physio Technology, Inc. Tissue and bone regeneration
EP0076074A1 (en) * 1981-09-24 1983-04-06 BENTALL, Richard Hugh Cameron Device for applying a high frequency electromagnetic field to living tissue to promote healing thereof
US4432361A (en) * 1982-01-18 1984-02-21 Sutter Biomedical Inc. Portable continuously self-monitoring bone healing device and method
US4454883A (en) * 1982-02-16 1984-06-19 Therafield Holdings Limited Electrotherapeutic apparatus
ES510489A0 (en) * 1982-03-16 1982-08-16 Rodriguez Delgado Jose Manu "ELECTRONIC SYSTEM FOR THE ACTIVATION, INHIBITION AND-OR MODIFICATION OF THE DEVELOPMENT AND FUNCTIONING OF CELLS, ORGANS AND ORGANISMS OF LIVING BEINGS".
US4467809A (en) * 1982-09-17 1984-08-28 Biolectron, Inc. Method for non-invasive electrical stimulation of epiphyseal plate growth
US4467808A (en) * 1982-09-17 1984-08-28 Biolectron, Inc. Method for preventing and treating osteoporosis in a living body by using electrical stimulation non-invasively
US4535775A (en) * 1983-02-10 1985-08-20 Biolectron, Inc. Method for treatment of non-union bone fractures by non-invasive electrical stimulation
FR2541902B1 (en) * 1983-03-04 1986-02-07 Cofrem International Sa THERMAL THERAPEUTIC APPARATUS
IT1159024B (en) * 1983-06-02 1987-02-25 Ruggero Cadossi METHOD AND DEVICE FOR THE TREATMENT OF FABRICS AND LIVING CELLS THROUGH ELECTROMAGNETIC FIELDS BUTTONS
US4654574A (en) * 1983-06-29 1987-03-31 Sheldon Thaler Apparatus for reactively applying electrical energy pulses to a living body
US4665898A (en) * 1984-05-23 1987-05-19 Maxwell Laboratories, Inc. Malignancy treatment
US4619264A (en) * 1984-06-14 1986-10-28 Singh Om P Method and apparatus for treatment of fresh fractures, delayed unions and non-unions of living bone
US4548208A (en) * 1984-06-27 1985-10-22 Medtronic, Inc. Automatic adjusting induction coil treatment device
US4574809A (en) * 1984-06-29 1986-03-11 Electro-Biology, Inc. Portable non-invasive electromagnetic therapy equipment
US4674482A (en) * 1984-09-12 1987-06-23 Irt, Inc. Pulse electro-magnetic field therapy device with auto bias circuit
US5198941A (en) * 1985-03-27 1993-03-30 Canon Kabushiki Kaisha Recording or reproducing apparatus
US4616629A (en) * 1985-05-24 1986-10-14 Electro-Biology, Inc. Coil construction for electromagnetic treatment of an afflicted body region
US4727878A (en) * 1985-09-26 1988-03-01 The University Of Michigan Functional electrical stimulation for pressure sore inhibition
US4738250A (en) * 1985-10-01 1988-04-19 Mems Technology, Incorporated Apparatus and method for micro-electric medical stimulation of cells of living animal tissue
US4765310A (en) * 1985-11-01 1988-08-23 Dynatens Research Corporation Electrical and magnetic pain treatment device
US4758429A (en) * 1985-11-04 1988-07-19 Gordon Robert T Method for the treatment of arthritis and inflammatory joint diseases
US5863531A (en) * 1986-04-18 1999-01-26 Advanced Tissue Sciences, Inc. In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework
US5902741A (en) * 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
US5000178A (en) * 1986-05-23 1991-03-19 Lti Biomedical, Inc. Shielded electromagnetic transducer
US4998532A (en) * 1986-05-23 1991-03-12 Lti Biomedical, Inc. Portable electro-therapy system
US5014699A (en) * 1986-05-23 1991-05-14 Trustees Of The University Of Pennsylvania Electromagnetic method and apparatus for healing living tissue
US4757804A (en) * 1986-08-25 1988-07-19 Lti Biomedical, Inc. Device for electromagnetic treatment of living tissue
US4818697A (en) * 1986-10-27 1989-04-04 Life Resonances, Inc. Techniques for enhancing the permeability of ions through membranes
US4932951A (en) * 1988-03-23 1990-06-12 Life Resonances, Inc. Method and apparatus for controlling tissue growth and an applied fluctuating magnetic field
US5117826A (en) * 1987-02-02 1992-06-02 Staodyn, Inc. Combined nerve fiber and body tissue stimulation apparatus and method
EP0325456B1 (en) * 1988-01-20 1995-12-27 G2 Design Limited Diathermy unit
US4895154A (en) * 1988-02-19 1990-01-23 Staodynamics, Inc. Electronic stimulating device for enhanced healing of soft tissue wounds
US5123898A (en) * 1988-03-23 1992-06-23 Life Resonances, Inc. Method and apparatus for controlling tissue growth with an applied fluctuating magnetic field
US5088976A (en) * 1988-03-23 1992-02-18 Life Resonances, Inc. Deformable magnetic field aiding coils for use in controlling tissue growth
US4993413A (en) * 1988-09-22 1991-02-19 The Research Foundation Of State University Of New York Method and apparatus for inducing a current and voltage in living tissue
US4919140A (en) * 1988-10-14 1990-04-24 Purdue Research Foundation Method and apparatus for regenerating nerves
US4982742A (en) * 1989-02-22 1991-01-08 C&Y Technology, Inc. Apparatus and method to facilitate healing of soft tissue wounds
US5107835A (en) * 1989-05-22 1992-04-28 Physiodynamics Electrotherapeutic treatment
US5099756A (en) * 1989-06-01 1992-03-31 Harry H. Leveen Radio frequency thermotherapy
CA2021506A1 (en) * 1989-08-17 1991-02-18 Abraham R. Liboff Electromagnetic treatment therapy for stroke victims
US5045050A (en) * 1989-11-15 1991-09-03 Life Resonances Method and apparatus for the treatment of cancer
US5183456A (en) * 1989-11-15 1993-02-02 Life Resonances, Inc. Method and apparatus for the treatment of cancer
US5186181A (en) * 1990-07-27 1993-02-16 Cafiero Franconi Radio frequency thermotherapy
US5181902A (en) * 1990-09-21 1993-01-26 American Medical Electronics, Inc. Double-transducer system for PEMF Therapy
US5195941A (en) * 1991-01-07 1993-03-23 American Medical Electronics, Inc. Contoured triangular transducer system for PEMF therapy
US5314401A (en) * 1991-03-29 1994-05-24 Amei Technologies Inc. Conformable PEMF transducer
US5158081A (en) * 1991-05-29 1992-10-27 Trillion Medical Resources, Inc. Method for treatment of soft tissue wounds by electrical stimulation
US5195940A (en) * 1991-06-20 1993-03-23 Iatromed, Inc. Method for increased production of growth factor in living tissue using an applied fluctuating magnetic field
DE4221739A1 (en) * 1991-07-09 1993-01-14 Fischer Ag LF pulse generator and transmission antenna for proton transport in blood - has coil which induces higher energy in electrolyte fluid than thermal energy, and within cell-specific amplitude window
AU661789B2 (en) * 1992-08-26 1995-08-03 Larkace Pty Ltd Magnetic field induction multi-pulse therapy
US5441528A (en) * 1992-09-25 1995-08-15 Symtonic, S.A. Method and system for applying low energy emission therapy
US5338286A (en) * 1992-12-08 1994-08-16 Electro-Biology, Inc. Electromagnetic bioresponse by selective spectral suppression in pulsed field stimulation
US5352458A (en) * 1992-12-21 1994-10-04 Applied Genetics Inc. Tanning method using DNA repair liposomes
US5395398A (en) * 1993-07-28 1995-03-07 C. R. Bard, Inc. Microelectric apparatus for the antisepsis, promulgation of healing and analgesia of wound and chronic skin ulcers
US5433735A (en) * 1993-09-27 1995-07-18 Zanakis; Michael F. Electrical stimulation technique for tissue regeneration
US5549639A (en) * 1994-09-16 1996-08-27 Sandia Corporation Non-invasive hyperthermia apparatus including coaxial applicator having a non-invasive radiometric receiving antenna incorporated therein and method of use thereof
US6121042A (en) * 1995-04-27 2000-09-19 Advanced Tissue Sciences, Inc. Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs
US5549640A (en) * 1995-06-08 1996-08-27 Fontenot; Mark G. Device and method for enhancement of wound healing
US5776175A (en) * 1995-09-29 1998-07-07 Esc Medical Systems Ltd. Method and apparatus for treatment of cancer using pulsed electromagnetic radiation
US5800458A (en) * 1996-09-30 1998-09-01 Rehabilicare, Inc. Compliance monitor for monitoring applied electrical stimulation
IL119683A (en) * 1996-11-25 2002-12-01 Rachel Lubart Method and device for light irradiation into tissue
US6250255B1 (en) * 1998-08-06 2001-06-26 Virginia Commonwealth University Methods and apparatus for alerting and/or repelling birds and other animals
US7105292B2 (en) * 2000-09-08 2006-09-12 New York University Screening methods used to identify compounds that modulate a response of a cell to ultraviolet radiation exposure
US7177695B2 (en) * 2001-12-17 2007-02-13 Cefamoptec Industries, Inc. Early stage wound healing using electromagnetic radiation
US20030181962A1 (en) * 2002-02-19 2003-09-25 Jackson Streeter Low power energy therapy methods for bioinhibition

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6334069B1 (en) * 1998-01-15 2001-12-25 Regenesis Biomedical, Inc. Pulsed electromagnetic energy treatment apparatus and method
US20020177885A1 (en) * 2000-10-24 2002-11-28 Eisfeld Timothy M. Method and device for selectively targeting cells within a three-dimensional specimen
US20040014052A1 (en) * 2002-07-22 2004-01-22 Kurtz Warren H. Process for regulating gene expression

Also Published As

Publication number Publication date
EP1592790A2 (en) 2005-11-09
AU2009225279A1 (en) 2009-10-29
US20050059153A1 (en) 2005-03-17
AU2004205915A1 (en) 2004-08-05
CA2514210A1 (en) 2004-08-05
WO2004065564A2 (en) 2004-08-05
EP1592790A4 (en) 2006-02-01

Similar Documents

Publication Publication Date Title
WO2004065564A3 (en) Electromagnetic activation of gene expression and cell growth
WO2010069317A8 (en) Bursts of electrical pulses in the treatment of pelvic disorders by electrical nerve stimulation
EP1546173A4 (en) Methods of down regulating target gene expression in vivo by introduction of interfering rna
WO2006066244A3 (en) Method for extending lifespan and delaying the onset of age-related disease
DE69636937D1 (en) THERAPEUTIC MOLECULES OBTAINED BY TRANS-CLEARANCE
AU2003267203A1 (en) Method for administering thermotherapy to prevent the growth of tumors
WO2006049812A3 (en) Process for treating a biological organism
RU2007140927A (en) COCHLEAR PROSTHETIC SYSTEM (OPTIONS), STIMULATION SYSTEM (OPTIONS) AND MACHINE READABLE MEDIA (OPTIONS)
WO2010118178A3 (en) Uterine electrical stimulation system and method
WO2005121323A3 (en) Methods for ex vivo propagation of somatic hair follicle stem cells
WO2005042692A3 (en) A method of inhibiting the expression of genes which mediate cellular cholesterol influx in animal cells and inhibiting the production of proteins resulting from the expression of such genes using cholesterol absorption inhibitors
WO2003083080A3 (en) Mixed- cell gene therapy
WO2005120633A3 (en) Method and associated apparatus for feedback therapy
AUPS112802A0 (en) Methods of inducing differentiation of stem cells into a specific cell lineage
WO2009141163A3 (en) Bioreactor and method for cultivating cells and tissues
WO2004010953A3 (en) Implantable artificial organ devices
AU2003214363A8 (en) Method to modify differentiation of pluripotential stem cells
AU2003279570A1 (en) Delivery agent, method of delivering a target substance to cells, method for producing delivery agent, composition for producing delivery agent, and kit for producing delivery agent
AU2003235783A1 (en) Method of fuel cell activation
EP1598421A3 (en) Oligoribuncloetides for influencing hair growth
WO2004003152A3 (en) Sos1 inhibitors
AU2003273250A1 (en) Triazaspiro compounds useful for treating or preventing pain
TW200504210A (en) A nucleolin antisense inhibiting growth of cancer cell
WO2005027830A3 (en) Chimeric transcription factor decoy oligonucleotides
WO2004101748A3 (en) A method of increasing yield in a plant and genes useful therefor

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2514210

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2004704094

Country of ref document: EP

Ref document number: 2004205915

Country of ref document: AU

ENP Entry into the national phase

Ref document number: 2004205915

Country of ref document: AU

Date of ref document: 20040121

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2004205915

Country of ref document: AU

WWP Wipo information: published in national office

Ref document number: 2004704094

Country of ref document: EP