WO2004073551A3 - Transscleral drug delivery device and related methods - Google Patents

Transscleral drug delivery device and related methods Download PDF

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Publication number
WO2004073551A3
WO2004073551A3 PCT/US2004/004625 US2004004625W WO2004073551A3 WO 2004073551 A3 WO2004073551 A3 WO 2004073551A3 US 2004004625 W US2004004625 W US 2004004625W WO 2004073551 A3 WO2004073551 A3 WO 2004073551A3
Authority
WO
WIPO (PCT)
Prior art keywords
eye
drug
delivery device
drug delivery
related methods
Prior art date
Application number
PCT/US2004/004625
Other languages
French (fr)
Other versions
WO2004073551A2 (en
Inventor
Anthony P Adamis
Joan W Miller
Mark J Mescher
Evangelos S Gragoudas
Jeffrey T Borenstein
Original Assignee
Massachusetts Eye & Ear Infirm
Draper Lab Charles S
Anthony P Adamis
Joan W Miller
Mark J Mescher
Evangelos S Gragoudas
Jeffrey T Borenstein
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Eye & Ear Infirm, Draper Lab Charles S, Anthony P Adamis, Joan W Miller, Mark J Mescher, Evangelos S Gragoudas, Jeffrey T Borenstein filed Critical Massachusetts Eye & Ear Infirm
Priority to US10/545,726 priority Critical patent/US20060167435A1/en
Publication of WO2004073551A2 publication Critical patent/WO2004073551A2/en
Publication of WO2004073551A3 publication Critical patent/WO2004073551A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Abstract

The invention provides a low-profile, dome-shaped body for attachment to a scleral surface of an eye and defining an internal cavity for receiving a drug or other pharmaceutically active agent. The device has an opening for controllably delivering the drug into the eye at therapeutically effective concentrations over a prolonged period of time. When attached, the device does not affect or otherwise restrict movement of the eye. Features of the invention include an optional drug inlet port and puncture guard, both designed for refilling the device while preventing a needle inserted through the inlet port from contacting the sclera.
PCT/US2004/004625 2003-02-18 2004-02-17 Transscleral drug delivery device and related methods WO2004073551A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US10/545,726 US20060167435A1 (en) 2003-02-18 2004-02-17 Transscleral drug delivery device and related methods

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44797103P 2003-02-18 2003-02-18
US60/447,971 2003-02-18

Publications (2)

Publication Number Publication Date
WO2004073551A2 WO2004073551A2 (en) 2004-09-02
WO2004073551A3 true WO2004073551A3 (en) 2004-12-29

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2004/004625 WO2004073551A2 (en) 2003-02-18 2004-02-17 Transscleral drug delivery device and related methods
PCT/US2004/004643 WO2004073765A2 (en) 2003-02-18 2004-02-18 Drug delivery device and syringe for filling the same

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2004/004643 WO2004073765A2 (en) 2003-02-18 2004-02-18 Drug delivery device and syringe for filling the same

Country Status (4)

Country Link
US (2) US20060167435A1 (en)
EP (1) EP1644057A2 (en)
JP (1) JP2006526430A (en)
WO (2) WO2004073551A2 (en)

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WO2004073765A3 (en) 2006-07-20
WO2004073765A9 (en) 2004-10-28
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WO2004073765A2 (en) 2004-09-02
US20060167435A1 (en) 2006-07-27

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