WO2005020847A2 - Graft materials containing bioactive substances, and methods for their manufacture - Google Patents
Graft materials containing bioactive substances, and methods for their manufacture Download PDFInfo
- Publication number
- WO2005020847A2 WO2005020847A2 PCT/US2004/027557 US2004027557W WO2005020847A2 WO 2005020847 A2 WO2005020847 A2 WO 2005020847A2 US 2004027557 W US2004027557 W US 2004027557W WO 2005020847 A2 WO2005020847 A2 WO 2005020847A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- extracellular matrix
- fgf
- level
- medical product
- hydrolysate
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/38—Stomach; Intestine; Goblet cells; Oral mucosa; Saliva
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3629—Intestinal tissue, e.g. small intestinal submucosa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3633—Extracellular matrix [ECM]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factors [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Nutrition Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physiology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE112004001553T DE112004001553T5 (en) | 2003-08-25 | 2004-08-25 | Transplanting materials containing bioactive substances and methods for their production |
US10/569,218 US8021692B2 (en) | 2003-08-25 | 2004-08-25 | Graft materials containing bioactive substances, and methods for their manufacture |
GB0605897A GB2424586B (en) | 2003-08-25 | 2004-08-25 | Graft materials containing bioactive substances, and methods for their manufacture |
US11/851,923 US8741352B2 (en) | 2003-08-25 | 2007-09-07 | Graft materials containing ECM components, and methods for their manufacture |
US12/762,058 US20100196480A1 (en) | 2003-08-25 | 2010-04-16 | Graft materials containing bioactive extracellular matrices and cells |
US13/225,585 US9504769B2 (en) | 2003-08-25 | 2011-09-06 | Graft materials containing bioactive substances, and methods for their manufacture |
US15/333,740 US10471182B2 (en) | 2003-08-25 | 2016-10-25 | Graft materials containing bioactive substances, and methods for their manufacture |
US15/843,159 US20180228939A1 (en) | 2003-08-25 | 2017-12-15 | Graft materials containing bioactive substances, and methods for their manufacture |
US16/453,459 US20190336650A1 (en) | 2003-08-25 | 2019-06-26 | Graft materials containing bioactive substances, and methods for their manufacture |
US16/801,831 US20200188559A1 (en) | 2003-08-25 | 2020-02-26 | Graft materials containing bioactive substances, and methods for their manufacture |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49774603P | 2003-08-25 | 2003-08-25 | |
US60/497,746 | 2003-08-25 |
Related Child Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/569,218 A-371-Of-International US8021692B2 (en) | 2003-08-25 | 2004-08-25 | Graft materials containing bioactive substances, and methods for their manufacture |
US43539306A Continuation-In-Part | 2003-08-25 | 2006-05-16 | |
US56921806A A-371-Of-International | 2003-08-25 | 2006-12-18 | |
US12/762,058 Continuation US20100196480A1 (en) | 2003-08-25 | 2010-04-16 | Graft materials containing bioactive extracellular matrices and cells |
US13/225,585 Continuation US9504769B2 (en) | 2003-08-25 | 2011-09-06 | Graft materials containing bioactive substances, and methods for their manufacture |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005020847A2 true WO2005020847A2 (en) | 2005-03-10 |
WO2005020847A3 WO2005020847A3 (en) | 2005-10-06 |
Family
ID=34272600
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/027557 WO2005020847A2 (en) | 2003-08-25 | 2004-08-25 | Graft materials containing bioactive substances, and methods for their manufacture |
Country Status (4)
Country | Link |
---|---|
US (7) | US8021692B2 (en) |
DE (1) | DE112004001553T5 (en) |
GB (1) | GB2424586B (en) |
WO (1) | WO2005020847A2 (en) |
Cited By (36)
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WO2008092011A2 (en) * | 2007-01-24 | 2008-07-31 | Cook Incorporated | Biofilm-inhibiting medical products |
US7442206B2 (en) | 2004-10-28 | 2008-10-28 | Cook Incorporated | Methods and systems for modifying vascular valves |
WO2009086499A2 (en) * | 2007-12-28 | 2009-07-09 | Cook Biotech Incorporated | Medical composition including an extracellular matrix particulate |
US7645229B2 (en) | 2003-09-26 | 2010-01-12 | Armstrong David N | Instrument and method for endoscopic visualization and treatment of anorectal fistula |
US7744621B2 (en) | 2004-12-06 | 2010-06-29 | Cook Incorporated | Inflatable occlusion devices, methods, and systems |
WO2010088678A2 (en) | 2009-02-02 | 2010-08-05 | Cook Biotech Incorporated | Medical bead products |
US7815923B2 (en) | 2005-12-29 | 2010-10-19 | Cook Biotech Incorporated | Implantable graft material |
US20100317080A1 (en) * | 2007-02-24 | 2010-12-16 | Zimmermann Hanngoerg | Method for the treatment of biological tissue of animal or human origin, such as porcine, bovine pericardium or human cadaver heart valves, and biological tissue treated accordingly |
WO2011006877A1 (en) * | 2009-07-14 | 2011-01-20 | Novartis Ag | Surface decontamination of prefilled containers in secondary packaging |
US7897167B2 (en) | 2005-06-21 | 2011-03-01 | Cook Incorporated | Implantable graft to close a fistula |
DE112009001300T5 (en) | 2008-05-29 | 2011-04-14 | Cook Biotech, Inc., West Lafayette | Devices and methods for the treatment of rectovaginal and other fistulas |
US8029560B2 (en) | 2007-09-12 | 2011-10-04 | Cook Medical Technologies Llc | Enhanced remodelable materials for occluding bodily vessels |
US8066732B2 (en) | 2004-12-30 | 2011-11-29 | Cook Incorporated | Inverting occlusion devices, methods, and systems |
WO2012018680A1 (en) | 2010-07-31 | 2012-02-09 | Global Therapeutics Llc | Methods and systems for generating a tissue pocket in a patient |
WO2012078669A1 (en) | 2010-12-10 | 2012-06-14 | Cook Biotech Incorporated | Quilted implantable graft |
EP2532310A2 (en) | 2005-04-29 | 2012-12-12 | Cook Biotech Incorporated | Volumetric grafts for treatment of fistulae and related methods and systems |
WO2012170538A2 (en) | 2011-06-06 | 2012-12-13 | Cook Medical Technologies Llc | Vascular occlusion devices and methods |
US8343536B2 (en) | 2007-01-25 | 2013-01-01 | Cook Biotech Incorporated | Biofilm-inhibiting medical products |
US8535349B2 (en) | 2007-07-02 | 2013-09-17 | Cook Biotech Incorporated | Fistula grafts having a deflectable graft body portion |
US8741354B2 (en) * | 2008-06-20 | 2014-06-03 | Cook Biotech Incorporated | Composite extracellular matrix materials and medical products formed therefrom |
US8764791B2 (en) | 2004-01-21 | 2014-07-01 | Cook Medical Technologies Llc | Implantable graft to close a fistula |
US8784889B2 (en) | 2004-07-30 | 2014-07-22 | Cook Biotech Incorporated | Graft with increased resistance to enzymatic degradation |
US8790414B2 (en) | 2006-11-10 | 2014-07-29 | Cook Biotech Incorporated | Graft for hysterotomy closure |
WO2014144370A1 (en) | 2013-03-15 | 2014-09-18 | Cook Biotech Incorporated | Ecm implant compositions and methods |
US8956378B2 (en) | 2008-02-29 | 2015-02-17 | Cook Biotech Incorporated | Coated embolization device |
US9113851B2 (en) | 2007-08-23 | 2015-08-25 | Cook Biotech Incorporated | Fistula plugs and apparatuses and methods for fistula plug delivery |
US9307995B2 (en) | 2006-06-15 | 2016-04-12 | Cook Medical Technologies Llc | Methods, systems and devices for the delivery of endoluminal prostheses |
US9538996B2 (en) | 2006-01-31 | 2017-01-10 | Cook Biotech Incorporated | Fistula grafts and related methods and systems for treating fistulae |
US9788821B2 (en) | 2005-04-29 | 2017-10-17 | Cook Biotech Incorporated | Physically modified extracellular matrix materials and uses thereof |
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US9956315B2 (en) | 2005-04-29 | 2018-05-01 | Cook Biotech Incorporated | Fistula graft with deformable sheet-form material |
US10143457B2 (en) | 2007-04-06 | 2018-12-04 | Cook Biotech Incorporated | Fistula plugs having increased column strength and fistula plug delivery apparatuses and methods |
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US10688219B2 (en) | 2008-06-10 | 2020-06-23 | Cook Biotech Incorporated | Quilted implantable graft |
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US11213545B2 (en) | 2017-03-02 | 2022-01-04 | University of Pittsburgh—of the Commonwealth System of Higher Education | ECM hydrogel for treating esophageal inflammation |
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US8568761B2 (en) * | 2005-07-15 | 2013-10-29 | Cormatrix Cardiovascular, Inc. | Compositions for regenerating defective or absent myocardium |
US8679176B2 (en) | 2007-12-18 | 2014-03-25 | Cormatrix Cardiovascular, Inc | Prosthetic tissue valve |
US8257434B2 (en) | 2007-12-18 | 2012-09-04 | Cormatrix Cardiovascular, Inc. | Prosthetic tissue valve |
US9480549B2 (en) | 2008-04-25 | 2016-11-01 | Allosource | Multi-layer tissue patches |
US9358320B2 (en) | 2008-04-25 | 2016-06-07 | Allosource | Multi-layer tissue patches |
US9192695B2 (en) | 2008-11-20 | 2015-11-24 | Allosource | Allografts combined with tissue derived stem cells for bone healing |
WO2010096458A1 (en) * | 2009-02-18 | 2010-08-26 | Cormatrix Cardiovascular, Inc. | Compositions and methods for preventing cardiac arrhythmia |
US20140286911A1 (en) | 2013-03-15 | 2014-09-25 | Allosource | Cell repopulated collagen matrix for soft tissue repair and regeneration |
US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
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US11826490B1 (en) | 2020-12-29 | 2023-11-28 | Acell, Inc. | Extracellular matrix sheet devices with improved mechanical properties and method of making |
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US6264992B1 (en) * | 1998-02-27 | 2001-07-24 | Purdue Research Foundation | Submucosa as a growth substrate for cells |
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US5281422A (en) | 1991-09-24 | 1994-01-25 | Purdue Research Foundation | Graft for promoting autogenous tissue growth |
US5275826A (en) | 1992-11-13 | 1994-01-04 | Purdue Research Foundation | Fluidized intestinal submucosa and its use as an injectable tissue graft |
US5711969A (en) | 1995-04-07 | 1998-01-27 | Purdue Research Foundation | Large area submucosal tissue graft constructs |
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2004
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- 2004-08-25 DE DE112004001553T patent/DE112004001553T5/en active Pending
- 2004-08-25 WO PCT/US2004/027557 patent/WO2005020847A2/en active Application Filing
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2010
- 2010-04-16 US US12/762,058 patent/US20100196480A1/en not_active Abandoned
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2011
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2016
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2017
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2019
- 2019-06-26 US US16/453,459 patent/US20190336650A1/en active Pending
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2020
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Also Published As
Publication number | Publication date |
---|---|
US20100196480A1 (en) | 2010-08-05 |
WO2005020847A3 (en) | 2005-10-06 |
US20170128628A1 (en) | 2017-05-11 |
GB2424586B (en) | 2008-05-28 |
US9504769B2 (en) | 2016-11-29 |
US10471182B2 (en) | 2019-11-12 |
US20180228939A1 (en) | 2018-08-16 |
GB2424586A (en) | 2006-10-04 |
US20110318419A1 (en) | 2011-12-29 |
US8021692B2 (en) | 2011-09-20 |
US20190336650A1 (en) | 2019-11-07 |
GB0605897D0 (en) | 2006-05-03 |
US20200188559A1 (en) | 2020-06-18 |
DE112004001553T5 (en) | 2006-08-10 |
US20070082060A1 (en) | 2007-04-12 |
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