WO2005030211A8 - Aerosolformulierung für die inhalation enthaltend ein anticholinergikum - Google Patents

Aerosolformulierung für die inhalation enthaltend ein anticholinergikum

Info

Publication number
WO2005030211A8
WO2005030211A8 PCT/EP2004/010564 EP2004010564W WO2005030211A8 WO 2005030211 A8 WO2005030211 A8 WO 2005030211A8 EP 2004010564 W EP2004010564 W EP 2004010564W WO 2005030211 A8 WO2005030211 A8 WO 2005030211A8
Authority
WO
WIPO (PCT)
Prior art keywords
inhalation
aerosol formulation
anticholinergic agent
pharmacologically compatible
ethanol
Prior art date
Application number
PCT/EP2004/010564
Other languages
English (en)
French (fr)
Other versions
WO2005030211A1 (de
Inventor
Georg Boeck
Friedrich Schmidt
Original Assignee
Boehringer Ingelheim Int
Boehringer Ingelheim Pharma
Georg Boeck
Friedrich Schmidt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EA200600497A priority Critical patent/EA010629B1/ru
Priority to JP2006527333A priority patent/JP5314243B2/ja
Priority to CA2540174A priority patent/CA2540174C/en
Priority to BRPI0414815-0A priority patent/BRPI0414815A/pt
Priority to AU2004275490A priority patent/AU2004275490B2/en
Priority to EP04765441A priority patent/EP1670472B8/de
Priority to DK04765441T priority patent/DK1670472T3/da
Priority to MXPA06003411A priority patent/MXPA06003411A/es
Priority to UAA200604363A priority patent/UA83506C2/uk
Priority to KR1020067008090A priority patent/KR101228405B1/ko
Application filed by Boehringer Ingelheim Int, Boehringer Ingelheim Pharma, Georg Boeck, Friedrich Schmidt filed Critical Boehringer Ingelheim Int
Priority to MEP-510/08A priority patent/MEP51008A/xx
Priority to NZ546667A priority patent/NZ546667A/en
Priority to YUP-2006/0208A priority patent/RS20060208A/sr
Priority to SI200430651T priority patent/SI1670472T1/sl
Priority to DE502004006606T priority patent/DE502004006606D1/de
Priority to PL04765441T priority patent/PL1670472T3/pl
Publication of WO2005030211A1 publication Critical patent/WO2005030211A1/de
Priority to IL174496A priority patent/IL174496A/en
Priority to NO20061833A priority patent/NO20061833L/no
Priority to HR20080140T priority patent/HRP20080140T3/xx
Publication of WO2005030211A8 publication Critical patent/WO2005030211A8/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Die vorliegende Erfindung betrifft Arzneimittelzubereitungen für die Inhalation enthaltend als alleinigen Wirkstoff eine Verbindung der Formel (I) worin X - ein Anion welches bevorzugt ausgewählt ist aus der Gruppe bestehend aus Chlorid, Bromid, Iodid, Sulfat, Phosphat, Methansulfonat, Nitrat, Maleat, Acetat, Citrat, Fumarat, Tartrat, Oxalat, Succinat, Benzoat und p-Toluolsulfonat, bedeutet, als Lösungsmittel Ethanol oder Mischungen aus Ethanol und Wasser, wenigstens eine pharmakologisch verträgliche Säure sowie gegebenenfalls weitere pharmakologisch verträgliche Hilfsstoffe und/oder Komplexbildner.
PCT/EP2004/010564 2003-09-26 2004-09-21 Aerosolformulierung für die inhalation enthaltend ein anticholinergikum WO2005030211A1 (de)

Priority Applications (19)

Application Number Priority Date Filing Date Title
MEP-510/08A MEP51008A (en) 2003-09-26 2004-09-21 Aerosol formulation for inhalation, containing an anticholinergic agent
JP2006527333A JP5314243B2 (ja) 2003-09-26 2004-09-21 抗コリン作用薬を含有する吸入用エアロゾル製剤
BRPI0414815-0A BRPI0414815A (pt) 2003-09-26 2004-09-21 formulação em aerossol para inalação contendo um anticolinérgico
AU2004275490A AU2004275490B2 (en) 2003-09-26 2004-09-21 Aerosol formulation for inhalation, containing an anticholinergic agent
EP04765441A EP1670472B8 (de) 2003-09-26 2004-09-21 Aerosolformulierung für die inhalation enthaltend ein antich olinergikum
DK04765441T DK1670472T3 (da) 2003-09-26 2004-09-21 Aerosolformulering til inhalation indeholdende et antikolinergikum
MXPA06003411A MXPA06003411A (es) 2003-09-26 2004-09-21 Formulacion de aerosol para inhalacion, que contiene un agente anticolinergico.
NZ546667A NZ546667A (en) 2003-09-26 2004-09-21 Aerosol formulation for inhalation, containing an anticholinergic agent
KR1020067008090A KR101228405B1 (ko) 2003-09-26 2004-09-21 항콜린제를 함유하는 흡입용 에어로졸 제제
EA200600497A EA010629B1 (ru) 2003-09-26 2004-09-21 Композиция для аэрозольной ингаляции, содержащая антихолинергическое средство
CA2540174A CA2540174C (en) 2003-09-26 2004-09-21 Aerosol formulation for inhalation, containing an anticholinergic agent
UAA200604363A UA83506C2 (uk) 2003-09-26 2004-09-21 Композиція для аерозольної інгаляції, яка містить антихолінергічний засіб
YUP-2006/0208A RS20060208A (en) 2003-09-26 2004-09-21 Aerosol formulation for inhalation, containing an anticholinergic agent
SI200430651T SI1670472T1 (sl) 2003-09-26 2004-09-21 Aerosolna formulacija za inhaliranje, ki vsebuje antiholinergik
DE502004006606T DE502004006606D1 (de) 2003-09-26 2004-09-21 Aerosolformulierung für die inhalation enthaltend ein antich olinergikum
PL04765441T PL1670472T3 (pl) 2003-09-26 2004-09-21 Preparat aerozolowy do inhalacji zawierający środek antycholinergiczny
IL174496A IL174496A (en) 2003-09-26 2006-03-23 Aerosol formulation for inhalation containing an anticholinergic agent
NO20061833A NO20061833L (no) 2003-09-26 2006-04-25 Aerosolformulgering for inhalering, inneholdende anticholinergt middel
HR20080140T HRP20080140T3 (en) 2003-09-26 2008-03-27 Aerosol formulation for inhalation, containing an anticholinergic agent

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10345065A DE10345065A1 (de) 2003-09-26 2003-09-26 Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE10345065.3 2003-09-26

Publications (2)

Publication Number Publication Date
WO2005030211A1 WO2005030211A1 (de) 2005-04-07
WO2005030211A8 true WO2005030211A8 (de) 2008-05-08

Family

ID=34306135

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/010564 WO2005030211A1 (de) 2003-09-26 2004-09-21 Aerosolformulierung für die inhalation enthaltend ein anticholinergikum

Country Status (34)

Country Link
US (1) US7579358B2 (de)
EP (2) EP1870101A1 (de)
JP (1) JP5314243B2 (de)
KR (1) KR101228405B1 (de)
CN (1) CN1856306A (de)
AR (1) AR046533A1 (de)
AT (1) ATE389407T1 (de)
AU (1) AU2004275490B2 (de)
BR (1) BRPI0414815A (de)
CA (1) CA2540174C (de)
CO (1) CO5680401A2 (de)
CY (1) CY1108135T1 (de)
DE (2) DE10345065A1 (de)
DK (1) DK1670472T3 (de)
EA (1) EA010629B1 (de)
EC (1) ECSP066460A (de)
ES (1) ES2303952T3 (de)
HR (1) HRP20080140T3 (de)
IL (1) IL174496A (de)
ME (1) MEP51008A (de)
MX (1) MXPA06003411A (de)
MY (1) MY139361A (de)
NO (1) NO20061833L (de)
NZ (1) NZ546667A (de)
PE (1) PE20050472A1 (de)
PL (1) PL1670472T3 (de)
PT (1) PT1670472E (de)
RS (2) RS20060208A (de)
SI (1) SI1670472T1 (de)
TW (1) TW200516078A (de)
UA (1) UA83506C2 (de)
UY (1) UY28527A1 (de)
WO (1) WO2005030211A1 (de)
ZA (1) ZA200601045B (de)

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