WO2005077337A3 - Dispersions prepared by use of self-stabilizing agents - Google Patents

Dispersions prepared by use of self-stabilizing agents Download PDF

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Publication number
WO2005077337A3
WO2005077337A3 PCT/US2005/002471 US2005002471W WO2005077337A3 WO 2005077337 A3 WO2005077337 A3 WO 2005077337A3 US 2005002471 W US2005002471 W US 2005002471W WO 2005077337 A3 WO2005077337 A3 WO 2005077337A3
Authority
WO
WIPO (PCT)
Prior art keywords
dispersion
self
stabilizing agents
dispersions prepared
agent
Prior art date
Application number
PCT/US2005/002471
Other languages
French (fr)
Other versions
WO2005077337A2 (en
Inventor
James E Kipp
Mark Doty
Christine L Rebbeck
Original Assignee
Baxter Int
James E Kipp
Mark Doty
Christine L Rebbeck
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int, James E Kipp, Mark Doty, Christine L Rebbeck filed Critical Baxter Int
Priority to JP2006552152A priority Critical patent/JP2007520555A/en
Priority to EP05712082A priority patent/EP1711163A2/en
Publication of WO2005077337A2 publication Critical patent/WO2005077337A2/en
Publication of WO2005077337A3 publication Critical patent/WO2005077337A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil

Abstract

The present invention relates to a dispersion of an active agent, which includes a multiphase system of an organic phase and an aqueous phase. The agent, preferably poorly water soluble, possesses surface active properties and itself serves as a dispersantor a stabilizer for the dispersion. The dispersion is suitable for pharmaceutical, veterinary, cosmetic, and agricultural applications, and is suitable for in vivo delivery, particularly by parenteral routes.
PCT/US2005/002471 2004-02-05 2005-01-26 Dispersions prepared by use of self-stabilizing agents WO2005077337A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2006552152A JP2007520555A (en) 2004-02-05 2005-01-26 Dispersants prepared by use of self-stabilizing agents
EP05712082A EP1711163A2 (en) 2004-02-05 2005-01-26 Dispersions prepared by use of self-stabilizing agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54237204P 2004-02-05 2004-02-05
US60/542,372 2004-02-05

Publications (2)

Publication Number Publication Date
WO2005077337A2 WO2005077337A2 (en) 2005-08-25
WO2005077337A3 true WO2005077337A3 (en) 2006-03-23

Family

ID=34860298

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/002471 WO2005077337A2 (en) 2004-02-05 2005-01-26 Dispersions prepared by use of self-stabilizing agents

Country Status (4)

Country Link
US (1) US20050196416A1 (en)
EP (1) EP1711163A2 (en)
JP (1) JP2007520555A (en)
WO (1) WO2005077337A2 (en)

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US20120052126A1 (en) * 2010-08-30 2012-03-01 Yashwant Pathak Nanoemulsions Containing Antioxidants And Other Health-Promoting Compounds
US8968757B2 (en) 2010-10-12 2015-03-03 Ecolab Usa Inc. Highly wettable, water dispersible, granules including two pesticides
US8835357B2 (en) * 2011-01-14 2014-09-16 Dow Agrosciences, Llc. Agricultural compositions comprising oil-in-water emulsions
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JP6962655B2 (en) * 2015-07-07 2021-11-05 ライフラフト バイオサイエンシーズ，インコーポレイテッド Low Sodium Poroxamer 188 Formulation and Usage
EP3124047A1 (en) 2015-07-28 2017-02-01 Merz Pharma GmbH & Co. KGaA Pentacyclic triterpenoids for injection lipolysis
KR20180082457A (en) * 2015-10-16 2018-07-18 마리누스 파마슈티컬스 인코포레이티드 Injectable neuro-steroid agents containing nanoparticles
US10391105B2 (en) 2016-09-09 2019-08-27 Marinus Pharmaceuticals Inc. Methods of treating certain depressive disorders and delirium tremens
BR112019007448A2 (en) * 2016-10-14 2019-07-16 Marinus Pharmaceuticals Inc Method of Administering a Neurosteroid to Cause Electroencephalographic Surgeup (eeg)
BR112019010131A2 (en) 2016-11-21 2019-10-08 Eirion Therapeutics Inc transdermal delivery of large agents
CA3145923A1 (en) 2019-08-05 2021-02-11 David Czekai Ganaxolone for use in treatment of status epilepticus
CN115501181A (en) * 2021-06-07 2022-12-23 武汉科福新药有限责任公司 Nadolol flexible nano gel emulsion and preparation method thereof
CN115969807B (en) * 2023-01-17 2023-09-19 青岛双鲸药业股份有限公司 Soft capsule content containing bioactive components and its preparation method

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Also Published As

Publication number Publication date
EP1711163A2 (en) 2006-10-18
WO2005077337A2 (en) 2005-08-25
JP2007520555A (en) 2007-07-26
US20050196416A1 (en) 2005-09-08

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