WO2005115535A3 - Treating a tumor or the like with electric fields at different frequencies - Google Patents

Treating a tumor or the like with electric fields at different frequencies Download PDF

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Publication number
WO2005115535A3
WO2005115535A3 PCT/IB2005/002410 IB2005002410W WO2005115535A3 WO 2005115535 A3 WO2005115535 A3 WO 2005115535A3 IB 2005002410 W IB2005002410 W IB 2005002410W WO 2005115535 A3 WO2005115535 A3 WO 2005115535A3
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WO
WIPO (PCT)
Prior art keywords
cells
field
tumor
electric fields
treating
Prior art date
Application number
PCT/IB2005/002410
Other languages
French (fr)
Other versions
WO2005115535A2 (en
Inventor
Yoram Palti
Original Assignee
Staden Ltd
Palti Yoram Prof
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Staden Ltd, Palti Yoram Prof filed Critical Staden Ltd
Priority to EP05767642A priority Critical patent/EP1740268A2/en
Priority to CA2563817A priority patent/CA2563817C/en
Priority to CN200580018206.6A priority patent/CN1976738B/en
Priority to JP2007509012A priority patent/JP4750784B2/en
Publication of WO2005115535A2 publication Critical patent/WO2005115535A2/en
Publication of WO2005115535A3 publication Critical patent/WO2005115535A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Electrotherapy Devices (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

Cells that are in the late anaphase or telophase stages of cell division are vulnerable to damage by AC electric fields that have specific frequency and field strength characteristics. The selective destruction of rapidly dividing cells can therefore be accomplished by imposing an AC electric field in a target region for extended periods of time. Some of the cells that divide while the field is applied will be damaged, but the cells that do not divide will not be harmed. This selectively damages rapidly dividing cells like tumor cells, but does not harm normal cells that are not dividing. Improved results may be achieved by using a field with two or more frequencies.
PCT/IB2005/002410 2004-04-23 2005-04-21 Treating a tumor or the like with electric fields at different frequencies WO2005115535A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP05767642A EP1740268A2 (en) 2004-04-23 2005-04-21 Treating a tumor or the like with electric fields at different frequencies
CA2563817A CA2563817C (en) 2004-04-23 2005-04-21 Treating a tumor or the like with electric fields at different frequencies
CN200580018206.6A CN1976738B (en) 2004-04-23 2005-04-21 Treating a tumor or the like with an electric field
JP2007509012A JP4750784B2 (en) 2004-04-23 2005-04-21 Treatment of tumors by electric fields of different frequencies

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56506504P 2004-04-23 2004-04-23
US60/565,065 2004-04-23

Publications (2)

Publication Number Publication Date
WO2005115535A2 WO2005115535A2 (en) 2005-12-08
WO2005115535A3 true WO2005115535A3 (en) 2006-04-06

Family

ID=35240980

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/002410 WO2005115535A2 (en) 2004-04-23 2005-04-21 Treating a tumor or the like with electric fields at different frequencies

Country Status (6)

Country Link
US (5) US8244345B2 (en)
EP (1) EP1740268A2 (en)
JP (2) JP4750784B2 (en)
CN (1) CN1976738B (en)
CA (1) CA2563817C (en)
WO (1) WO2005115535A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11850422B2 (en) 2019-04-23 2023-12-26 Boston Scientific Scimed, Inc. Electrodes for electrical stimulation to treat cancer

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US8706261B2 (en) 2014-04-22
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US8244345B2 (en) 2012-08-14
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US20120283726A1 (en) 2012-11-08
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