WO2007022248A3 - Methods of detection of cancer using peptide profiles - Google Patents
Methods of detection of cancer using peptide profiles Download PDFInfo
- Publication number
- WO2007022248A3 WO2007022248A3 PCT/US2006/031957 US2006031957W WO2007022248A3 WO 2007022248 A3 WO2007022248 A3 WO 2007022248A3 US 2006031957 W US2006031957 W US 2006031957W WO 2007022248 A3 WO2007022248 A3 WO 2007022248A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cancer
- detection
- profiles
- methods
- peptide profiles
- Prior art date
Links
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0027—Methods for using particle spectrometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
Abstract
The disclosed methods address the identification and monitoring of cancer in a subject using serum peptide profiles. Such profiles allow the detection of the differential presence of certain serum peptide markers in comparison with controls. The profiles can be determined employing mass spectrometry.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/063,968 US7972770B2 (en) | 2005-08-16 | 2006-08-16 | Methods of detection of cancer using peptide profiles |
US13/116,956 US20110312522A1 (en) | 2005-08-16 | 2011-05-26 | Methods of detection of cancer using peptide profiles |
US14/031,712 US20140234880A1 (en) | 2005-08-16 | 2013-09-19 | Methods of detection of cancer using peptide profiles |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70867605P | 2005-08-16 | 2005-08-16 | |
US60/708,676 | 2005-08-16 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/063,968 A-371-Of-International US7972770B2 (en) | 2005-08-16 | 2006-08-16 | Methods of detection of cancer using peptide profiles |
US13/116,956 Division US20110312522A1 (en) | 2005-08-16 | 2011-05-26 | Methods of detection of cancer using peptide profiles |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007022248A2 WO2007022248A2 (en) | 2007-02-22 |
WO2007022248A3 true WO2007022248A3 (en) | 2009-05-14 |
Family
ID=37758335
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/031957 WO2007022248A2 (en) | 2005-08-16 | 2006-08-16 | Methods of detection of cancer using peptide profiles |
Country Status (2)
Country | Link |
---|---|
US (3) | US7972770B2 (en) |
WO (1) | WO2007022248A2 (en) |
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ES2543341T3 (en) * | 2005-09-13 | 2015-08-18 | National Research Council Of Canada | Methods and compositions to modulate the activity of tumor cells |
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US10049447B2 (en) * | 2013-11-06 | 2018-08-14 | H. Lee Moffitt Cancer Center and Research Insititute, Inc. | Pathology case review, analysis and prediction |
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CN105384805B (en) * | 2015-10-16 | 2018-05-04 | 上海市肺科医院 | A kind of diagnosis polypeptide and its application |
WO2018039137A1 (en) * | 2016-08-22 | 2018-03-01 | Jo Eung Joon | Database management using a matrix-assisted laser desorption/ionization time-of-flight mass spectrometer |
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WO2018081691A1 (en) * | 2016-10-28 | 2018-05-03 | Frontier Diagnostics, Llc | Imaging mass spectrometry and uses thereof |
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CN108169184B (en) * | 2017-09-05 | 2021-01-05 | 哈尔滨工业大学 | Establishment method and application of tumor classification identification model |
US10692605B2 (en) | 2018-01-08 | 2020-06-23 | International Business Machines Corporation | Library screening for cancer probability |
JP7336097B2 (en) | 2019-07-19 | 2023-08-31 | 京都府公立大学法人 | Peptide markers for breast cancer |
JP7310692B2 (en) | 2020-04-21 | 2023-07-19 | 株式会社島津製作所 | Theoretical mass table display system |
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WO2006099126A2 (en) * | 2005-03-11 | 2006-09-21 | Ciphergen Biosystems, Inc. | Biomarkers for ovarian cancer and endometrial cancer: hepcidin |
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ITRM20040098A1 (en) * | 2004-02-25 | 2004-05-25 | Univ Roma | OLIGOCLONAL ANTI-CLASTERINE ANTIBODIES FOR THE DIAGNOSIS OF NEOPLASIE AND THE PREDICTION OF THEIR DEGREE OF MALIGNITY, DIAGNOSTIC METHOD AND RELATED KITS. |
WO2006044666A2 (en) * | 2004-10-15 | 2006-04-27 | Northeastern University | Detection of disease associated proteolysis by direct mass spectrometry analysis of low molecular weight peptides |
-
2006
- 2006-08-16 WO PCT/US2006/031957 patent/WO2007022248A2/en active Application Filing
- 2006-08-16 US US12/063,968 patent/US7972770B2/en not_active Expired - Fee Related
-
2011
- 2011-05-26 US US13/116,956 patent/US20110312522A1/en not_active Abandoned
-
2013
- 2013-09-19 US US14/031,712 patent/US20140234880A1/en not_active Abandoned
Patent Citations (4)
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US20050059013A1 (en) * | 2002-08-06 | 2005-03-17 | The Johns Hopkins University | Use of biomarkers for detecting ovarian cancer |
WO2006034032A2 (en) * | 2004-09-17 | 2006-03-30 | The Johns Hopkins University | Biomarkers for breast cancer |
WO2006099126A2 (en) * | 2005-03-11 | 2006-09-21 | Ciphergen Biosystems, Inc. | Biomarkers for ovarian cancer and endometrial cancer: hepcidin |
US20070054329A1 (en) * | 2005-03-11 | 2007-03-08 | Ciphergen Biosystems, Inc. | Biomarker for ovarian and endometrial cancer: hepcidin |
Non-Patent Citations (5)
Title |
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CAPUTO ET AL.: "Peptide profiling in epithelial tumor plasma by the emerging proteomic techniques.", J OF CHROMATOGRAPHY., vol. 819, May 2005 (2005-05-01), pages 59 - 66, XP002496511, DOI: doi:10.1016/j.jchromb.2005.01.022 * |
FUNG ET AL.: "Classification of cancer types by measuring variants of host response proteins using SELDI serum assays.", INT J CANCER., vol. 115, 2005, pages 783 - 789, XP002504152, DOI: doi:10.1002/ijc.20928 * |
KOOMEN ET AL.: "Direct tandem mass spectrometry reveals limitations in protein profiling experiments for plasma biomarker discover.", J OF PROTEOME RESEARCH., vol. 4, May 2005 (2005-05-01), pages 972 - 981 * |
SONG ET AL.: "Quantification of fragments of human serum inter-alpha-trypsin inhibitor heavy chain 4 by a surface-enhanced laser desorption/ionization-based immunoassay.", CLINICAL CHEMISTRY, vol. 52, June 2006 (2006-06-01), pages 1045 - 1053, XP002584414, DOI: doi:10.1373/clinchem.2005.065722 * |
VILLANUEVA ET AL.: "Differential exoprotease activities confer tumor-specific serum peptidome pattems.", J OF CLINICAL INVESTIGATION., vol. 116, January 2006 (2006-01-01), pages 271 - 284, XP002434651, DOI: doi:10.1172/JCI26022 * |
Also Published As
Publication number | Publication date |
---|---|
US20090208921A1 (en) | 2009-08-20 |
WO2007022248A2 (en) | 2007-02-22 |
US20110312522A1 (en) | 2011-12-22 |
US7972770B2 (en) | 2011-07-05 |
US20140234880A1 (en) | 2014-08-21 |
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