WO2007023461A3 - Method for detection of micro-organisms and antibiotic resistance markers and nucleic acid oligonucleotides therefor - Google Patents

Method for detection of micro-organisms and antibiotic resistance markers and nucleic acid oligonucleotides therefor Download PDF

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Publication number
WO2007023461A3
WO2007023461A3 PCT/IB2006/052919 IB2006052919W WO2007023461A3 WO 2007023461 A3 WO2007023461 A3 WO 2007023461A3 IB 2006052919 W IB2006052919 W IB 2006052919W WO 2007023461 A3 WO2007023461 A3 WO 2007023461A3
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WO
WIPO (PCT)
Prior art keywords
organisms
micro
nucleic acid
antibiotic resistance
detection
Prior art date
Application number
PCT/IB2006/052919
Other languages
French (fr)
Other versions
WO2007023461A2 (en
Inventor
Gerd Luedke
Johannes Bacher
Jens-Peter Seher
Holger Engel
Juergen Lauber
Andre Bahr
Helge Lubenow
Original Assignee
Philips Intellectual Property
Koninkl Philips Electronics Nv
Gerd Luedke
Johannes Bacher
Jens-Peter Seher
Holger Engel
Juergen Lauber
Andre Bahr
Helge Lubenow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Intellectual Property, Koninkl Philips Electronics Nv, Gerd Luedke, Johannes Bacher, Jens-Peter Seher, Holger Engel, Juergen Lauber, Andre Bahr, Helge Lubenow filed Critical Philips Intellectual Property
Priority to JP2008527574A priority Critical patent/JP2009505651A/en
Publication of WO2007023461A2 publication Critical patent/WO2007023461A2/en
Publication of WO2007023461A3 publication Critical patent/WO2007023461A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays

Abstract

The present invention relates to methods of detecting one or more micro¬ organisms and/or one or more antibiotic resistance markers in a sample, comprising identifying the presence of distinct nucleic acid regions. Primers and probes suitable for use in such methods are provided.
PCT/IB2006/052919 2005-08-26 2006-08-23 Method for detection of micro-organisms and antibiotic resistance markers and nucleic acid oligonucleotides therefor WO2007023461A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008527574A JP2009505651A (en) 2005-08-26 2006-08-23 Method for detection of microbial and antibiotic resistance markers and nucleic acid oligonucleotides therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05107867.3 2005-08-26
EP05107867 2005-08-26

Publications (2)

Publication Number Publication Date
WO2007023461A2 WO2007023461A2 (en) 2007-03-01
WO2007023461A3 true WO2007023461A3 (en) 2008-01-03

Family

ID=37772009

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/052919 WO2007023461A2 (en) 2005-08-26 2006-08-23 Method for detection of micro-organisms and antibiotic resistance markers and nucleic acid oligonucleotides therefor

Country Status (3)

Country Link
JP (1) JP2009505651A (en)
CN (1) CN101248190A (en)
WO (1) WO2007023461A2 (en)

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US8883423B2 (en) 2010-10-22 2014-11-11 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes

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CA2348042A1 (en) 2001-06-04 2002-12-04 Ann Huletsky Sequences for detection and identification of methicillin-resistant staphylococcus aureus
US11834720B2 (en) 2005-10-11 2023-12-05 Geneohm Sciences, Inc. Sequences for detection and identification of methicillin-resistant Staphylococcus aureus (MRSA) of MREJ types xi to xx
WO2008051285A2 (en) 2006-04-01 2008-05-02 Medical Service Consultation International, Llc Methods and compositions for detecting fungi and mycotoxins
EP1978111B1 (en) 2007-04-02 2013-03-27 Gen-Probe Incorporated Compositions, kits and related methods for the detection and/or monitoring of Pseudomonas aeruginosa
EP2150625B1 (en) 2007-04-19 2013-03-20 Molecular Detection Inc. Methods, compositions and kits for detection and analysis of antibiotic-resistant bacteria
ATE525483T1 (en) * 2007-07-30 2011-10-15 Univ Ulm OLIGONUCLEOTIDE PROBE AND METHOD FOR DETECTING OR DISTINCTING MICROORGANISMS IN A SAMPLE
WO2009086218A2 (en) * 2007-12-21 2009-07-09 Gen-Probe Incorporated Detection of antibiotic-resistant microorganisms
US7595164B2 (en) 2007-12-26 2009-09-29 Gen-Probe Incorporated Compositions and methods to detect Candida albicans nucleic acid
AU2012202811B2 (en) * 2007-12-26 2014-02-13 Gen-Probe Incorporated Compositions and methods to detect Candida albicans nucleic acid
FI121884B (en) 2008-01-17 2011-05-31 Mobidiag Oy Method for detection and identification of methicillin-resistant staphylococci, probe and test kit for the method
US20100068718A1 (en) 2008-08-22 2010-03-18 Hooper Dennis G Methods and Compositions for Identifying Yeast
FI20095544A0 (en) * 2009-05-15 2009-05-15 Juha Kirveskari Method and kit for identifying antibiotic resistant bacteria
EP2473639A2 (en) * 2009-09-04 2012-07-11 Intelligent Medical Devices, Inc. OPTIMIZED PROBES AND PRIMERS AND METHODS OF USING SAME FOR THE DETECTION, SCREENING, ISOLATION AND SEQUENCING OF MRSA, MSSA, STAPHYLOCOCCUS MARKERS AND THE ANTIBIOTIC RESISTANCE GENE mecA
EP2473630B1 (en) * 2009-09-04 2017-11-08 QIAGEN GmbH Optimized probes and primers and methods of using same for the detection, screening, isolation and sequencing of vancomycin resistance genes and vancomycin resistant enterococci
US8962251B2 (en) 2009-10-08 2015-02-24 Medical Service Consultation International, Llc Methods and compositions for identifying sulfur and iron modifying bacteria
CN101880728B (en) * 2010-07-29 2012-03-21 河南农业大学 Multiple PCR detection primer of enterococcus and method thereof
EP2630517B1 (en) 2010-10-22 2016-03-16 T2 Biosystems, Inc. Nmr systems and methods for the rapid detection of analytes
EP2839038B1 (en) 2012-04-20 2019-01-16 T2 Biosystems, Inc. Compositions and methods for detection of candida species
CN102952881B (en) * 2012-10-25 2014-02-26 浙江省淡水水产研究所 Enterobacter cloacae specific PCR (polymerase chain reaction) detection primer
US8956821B2 (en) 2013-02-06 2015-02-17 Medical Service Consultation International, Llc Methods and compositions for detecting Aspergillus terreus, Aspergillus niger, and mycotoxins
WO2017044880A1 (en) 2015-09-09 2017-03-16 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics infectious disease and other health conditions associated with antibiotic usage
US11519016B2 (en) 2016-01-21 2022-12-06 T2 Biosystems, Inc. NMR methods and systems for the rapid detection of bacteria
US9889165B2 (en) 2016-04-21 2018-02-13 Naked Biome, Inc. Compositions and methods for treatment of skin disorders
EP3472355A4 (en) 2016-06-15 2020-07-29 Genecapture, Inc. Compositions, methods and devices comprising stem-loop captor molecules
WO2019079612A1 (en) * 2017-10-20 2019-04-25 Naked Biome, Inc. Systems and methods for bacterial detection and treatment
EP3599283A1 (en) * 2018-07-25 2020-01-29 Blue DNA Companion Method for assessing fecal pollution in water
CN113502354A (en) * 2021-07-14 2021-10-15 中国医学科学院输血研究所 Pathogen detection primer and probe set for transplanted patient infection, kit and application

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US6512105B1 (en) * 1986-11-24 2003-01-28 Gen-Probe Incorporated Methods for making oligonucleotide probes for the detection and/or quantitation of non-viral organisms
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Patent Citations (3)

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WO2000052203A2 (en) * 1999-03-02 2000-09-08 King's College London Identification of bacteria by amplification and probing
US20050079490A1 (en) * 1999-12-23 2005-04-14 Roche Diagnostics Corporation Method for quickly detecting microbial dna/rna, kit therefor and the use of said method

Non-Patent Citations (2)

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Title
DE VRIES JOHANN ET AL: "Spread of recombinant DNA by roots and pollen of transgenic potato plants, identified by highly specific biomonitoring using natural transformation of an Acinetobacter sp.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY AUG 2003, vol. 69, no. 8, August 2003 (2003-08-01), pages 4455 - 4462, XP002445290, ISSN: 0099-2240 *
MITTERER G ET AL: "Microarray-based identification of bacteria in clinical samples by solid-phase PCR amplification of 23S ribosomal DNA sequences", JOURNAL OF CLINICAL MICROBIOLOGY, WASHINGTON, DC, US, vol. 42, no. 3, March 2004 (2004-03-01), pages 1048 - 1057, XP002363929, ISSN: 0095-1137 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8883423B2 (en) 2010-10-22 2014-11-11 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US9360457B2 (en) 2010-10-22 2016-06-07 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes

Also Published As

Publication number Publication date
CN101248190A (en) 2008-08-20
JP2009505651A (en) 2009-02-12
WO2007023461A2 (en) 2007-03-01

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