WO2007037894A2 - Intraocular pressure control - Google Patents
Intraocular pressure control Download PDFInfo
- Publication number
- WO2007037894A2 WO2007037894A2 PCT/US2006/033720 US2006033720W WO2007037894A2 WO 2007037894 A2 WO2007037894 A2 WO 2007037894A2 US 2006033720 W US2006033720 W US 2006033720W WO 2007037894 A2 WO2007037894 A2 WO 2007037894A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- chamber
- fluid
- infusion
- providing
- irrigating fluid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M3/00—Medical syringes, e.g. enemata; Irrigators
- A61M3/02—Enemata; Irrigators
- A61M3/0233—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M3/00—Medical syringes, e.g. enemata; Irrigators
- A61M3/02—Enemata; Irrigators
- A61M3/0204—Physical characteristics of the irrigation fluid, e.g. conductivity or turbidity
- A61M3/0216—Pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3379—Masses, volumes, levels of fluids in reservoirs, flow rates
- A61M2205/3389—Continuous level detection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M3/00—Medical syringes, e.g. enemata; Irrigators
- A61M3/02—Enemata; Irrigators
- A61M3/0202—Enemata; Irrigators with electronic control means or interfaces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M3/00—Medical syringes, e.g. enemata; Irrigators
- A61M3/02—Enemata; Irrigators
- A61M3/0233—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs
- A61M3/0254—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs the liquid being pumped
Definitions
- the present invention generally pertains to microsurgical systems and more
- probes are inserted into the operative site to cut, remove, or otherwise manipulate tissue.
- fluid is typically infused into the eye, and the infusion fluid and tissue are aspirated from the surgical site.
- the present invention is a method of controlling intraocular pressure
- An infusion chamber containing an irrigating fluid is
- the infusion chamber is
- a flow rate of the fluid within a fluid line fluidly coupled to the surgical device is measured.
- intraocular pressure is calculated with the computer in response to the signal.
- the pressurized gas is adjusted in response to a second signal from the computer to
- an infusion chamber is provided.
- infusion chamber has a first chamber for holding irrigating fluid and a second chamber
- the first chamber is not fluidly coupled to the second chamber.
- An irrigating fluid is provided from an infusion source to the first chamber and the second chamber.
- the irrigating fluid is provided to a surgical device from the first
- the irrigating fluid in the first chamber reaches a bottom limit. Upon such ending, the irrigating fluid is provided to the surgical device from the second chamber, and the first
- Figure 1 is a schematic diagram illustrating infusion control in an ophthalmic microsurgical system
- Figure 2 is a schematic diagram illustrating infusion control and irrigation control
- microsurgical system 10 includes a pressure cuff 12; an infusion source 14; a dual infusion chamber 16 having a chamber 16a and a chamber 16b; fluid level sensors 18 and
- microprocessor 28 gas manifolds 30 and 32; a pressurized gas source 34; proportional
- solenoid valves 36, 38, and 40 Dual infusion
- gas lines 84 and 86 are preferably disposed in a surgical
- Infusion source 14 Infusion source 14; dual infusion chamber 16; flow sensor 22; filters 24 and 26; and surgical device 29 are fluidly coupled via infusion fluid lines 70-80.
- Infusion fluid lines 70-80 Infusion pump
- source 14 dual infusion chamber 16, gas manifolds 30 and 32; pressurized gas source 34;
- actuators 56, 58, 60, and 62 are fluidly coupled via gas lines 82, 84, 86, 88, 90, 92, 94, and 96.
- proportional solenoid valves 36-40; on/off solenoid valves 42-54; actuators 56-62; and pressure transducers 64-68 are electrically coupled via interfaces 100, 102, 104, 106,
- Infusion source 14 is preferably a flexible infusion source.
- Fluid level sensors 18 and 20 are preferably capable of
- Flow sensor 22 may be any suitable device for measuring the flow rate of fluid within fluid line 80.
- Flow sensor 22 is preferably a non-invasive flow sensor.
- Filters 24 and 26 are hydrophobic micro-bacterial filters.
- a preferred filter is the Versapor ® membrane
- Microprocessor 28 is capable of implementing feedback control, and preferably PID
- Surgical device 29 may be any suitable device for providing surgical irrigating fluid to the eye but is preferably an infusion cannula, an irrigation handpiece, or and
- Surgical irrigating fluid 140 may be any surgical irrigating fluid suitable for ophthalmic use, such as, by way of example, BSS PLUS®
- intraocular irrigating solution available from Alcon Laboratories, Inc.
- the pressurizing of infusion source 14 is preferably performed by pressure cuff
- microprocessor 28 sends a control signal to open solenoid valve
- Microprocessor 28 also sends a control signal to open proportional solenoid
- valve 40 via interface 104 so that manifold 30 supplies the appropriate amount of
- Pressure transducer 68 senses the pressure within gas line 82 and provides a corresponding signal to microprocessor 28 via interface
- Solenoid valves 48-54 are initially open so that manifold 32 provides pressurized air
- valves 48-54 actuates actuators 56-62 to open fluid lines 72-78. After all 1 chambers and fluid lines are primed, microprocessor 28 closes actuators 56-62 and thus fluid lines 72-
- infusion source 14 may be performed solely via
- Input 134 may be any suitable input device but is
- Chamber 16b is preferably the initial
- Microprocessor 28 sends appropriate control signals to open
- solenoid valve 44 and to open proportional solenoid valve 36 (via interface 100) to provide an appropriate level of pressurized air to chamber 16b.
- Pressure transducer 64 is
- microprocessor 28 senses the pressure within gas line 84 and provides a corresponding signal to microprocessor 28 via interface 124. Microprocessor 28 also sends an appropriate control
- Chamber 16b supplies pressurized fluid
- Microprocessor 28 calculates a predicted intraocular pressure using the
- Microprocessor 28 then sends an appropriate feedback control
- Fluid level sensor 20 continuously monitors the decrease in the level of fluid 140 in chamber 16b during surgery and provides a corresponding signal to microprocessor 28
- Microprocessor 28 performs adjustments to the air pressure provided
- microprocessor 28 closes solenoid valve 44 and actuator 60 and opens solenoid
- Chamber 16a is now the active infusion chamber.
- Microprocessor 28 sends an appropriate control signal to proportional solenoid valve 38
- interface 102 via interface 102 to provide an appropriate level of pressurized air to chamber 16a.
- Pressure transducer 66 senses the pressure within gas line 86 and provides a corresponding signal to microprocessor 28 via interface 122. Chamber 16a supplies
- pressurized fluid 140 to the eye via fluid lines 76 and 80 and surgical device 29.
- sensor 22 measures the flow rate of fluid 140 and provides a corresponding signal to
- Microprocessor 28 via interface 132.
- Microprocessor 28 calculates the predicted intraocular pressure as described above and the sends an appropriate feedback signal to
- proportional solenoid valve 38 to maintain the predicted intraocular pressure at or near the desired intraocular pressure during all portions of the surgery.
- Fluid level sensor 18 continuously monitors the decrease in the level of fluid 140
- microprocessor 28 performs adjustments to the air pressure provided
- microprocessor 28 switches chamber 16b to active infusion, makes chamber 16a inactive, and refills chamber 16a with fluid 140 via fluid line 72. This cycling between
- Infusion source 14 is preferably mom ' tored via a fluid level sensor (not shown) capable of providing a signal to microprocessor 28 via interface 112 when source 14
- Chambers 16a and 16b also preferably each have a volume that enable infusion source 14 to be exchanged, when near empty, without interrupting
- chambers 16a and 16b preferably each have a
- volume of about 30 cc. Such volume allows about two minutes for a near empty infusion source 14 to be exchanged during conditions of maximum flow (e.g. core vitrectomy), hi
- microprocessor 28 can
- microprocessor 28 can preferably continue surgery using only one active chamber. In the case of failure of both chambers 16a and 16b, microprocessor 28 can preferably continue surgery using only
- FIG. 2 shows a modified ophthalmic microsurgical system 10a.
- system 10a is similar to microsurgical system 10 except that it has an irrigation system in
- system 10a is identical to system 10 except that system 10a also includes an irrigation source
- irrigation source 200 is pressurized solely by gravity.
- microsurgical system 10a allows surgical
- irrigating fluid 140 to be delivered to surgical device 29 via fluid line 80 (infusion), and
- Microprocessor 28 can calculate flow information for fluid
Abstract
Description
Claims
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06790076.1A EP1928538B1 (en) | 2005-09-28 | 2006-08-29 | Intraocular pressure control |
KR1020087010191A KR101287163B1 (en) | 2005-09-28 | 2006-08-29 | Intraocular pressure control |
AU2006295256A AU2006295256B2 (en) | 2005-09-28 | 2006-08-29 | Intraocular pressure control |
MX2008003363A MX2008003363A (en) | 2005-09-28 | 2006-08-29 | Intraocular pressure control. |
CA2620928A CA2620928C (en) | 2005-09-28 | 2006-08-29 | Intraocular pressure control |
BR122018073489A BR122018073489B8 (en) | 2005-09-28 | 2006-08-29 | intraocular pressure microsurgical system |
ES06790076.1T ES2534552T3 (en) | 2005-09-28 | 2006-08-29 | Intraocular pressure control |
CN2006800361978A CN101277735B (en) | 2005-09-28 | 2006-08-29 | Microsurgery system for controlling intraocular pressure |
BRPI0616420A BRPI0616420B8 (en) | 2005-09-28 | 2006-08-29 | method for switching between a first and a second chamber to maintain a desired pressure |
JP2008533364A JP5420904B2 (en) | 2005-09-28 | 2006-08-29 | Intraocular pressure control |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/237,503 US7326183B2 (en) | 2005-09-28 | 2005-09-28 | Intraocular pressure control |
US11/237,503 | 2005-09-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007037894A2 true WO2007037894A2 (en) | 2007-04-05 |
WO2007037894A3 WO2007037894A3 (en) | 2007-07-12 |
Family
ID=37900212
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/033720 WO2007037894A2 (en) | 2005-09-28 | 2006-08-29 | Intraocular pressure control |
Country Status (14)
Country | Link |
---|---|
US (3) | US7326183B2 (en) |
EP (1) | EP1928538B1 (en) |
JP (3) | JP5420904B2 (en) |
KR (1) | KR101287163B1 (en) |
CN (1) | CN101277735B (en) |
AR (1) | AR058463A1 (en) |
AU (1) | AU2006295256B2 (en) |
BR (2) | BR122018073489B8 (en) |
CA (1) | CA2620928C (en) |
ES (1) | ES2534552T3 (en) |
MX (1) | MX2008003363A (en) |
RU (2) | RU2411022C2 (en) |
TW (1) | TWI451885B (en) |
WO (1) | WO2007037894A2 (en) |
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US11311661B2 (en) | 2018-03-09 | 2022-04-26 | D.O.R.C. Dutch Ophthalmic Research Center (International) B.V. | Ophthalmic pressure control system, a kit of parts and a method |
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