WO2007081386A3 - Microfluidic devices and methods of use - Google Patents
Microfluidic devices and methods of use Download PDFInfo
- Publication number
- WO2007081386A3 WO2007081386A3 PCT/US2006/021286 US2006021286W WO2007081386A3 WO 2007081386 A3 WO2007081386 A3 WO 2007081386A3 US 2006021286 W US2006021286 W US 2006021286W WO 2007081386 A3 WO2007081386 A3 WO 2007081386A3
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- WIPO (PCT)
- Prior art keywords
- methods
- microfluidic devices
- channel
- useful
- flow
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C12N15/1034—Isolating an individual clone by screening libraries
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Abstract
The present invention provides novel microfluidic devices and methods that are useful for performing high-throughput screening assays and combinatorial chemistry. The device can include a plurality of electrically addressable, channel bearing fluidic modules integrally arranged on a microfabricated substrate such that a continuous channel is provided for flow of immiscible fluids.
Applications Claiming Priority (6)
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USPCT/US2006/000931 | 2006-01-11 | ||
USPCT/US2006/000931 | 2006-01-11 | ||
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US60/763,524 | 2006-01-30 | ||
US77128606P | 2006-02-07 | 2006-02-07 | |
US60/771,286 | 2006-02-07 |
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WO2007081386A2 WO2007081386A2 (en) | 2007-07-19 |
WO2007081386A3 true WO2007081386A3 (en) | 2007-11-08 |
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PCT/US2006/021380 WO2007081387A1 (en) | 2006-01-11 | 2006-06-01 | Microfluidic devices, methods of use, and kits for performing diagnostics |
PCT/US2006/021286 WO2007081386A2 (en) | 2006-01-11 | 2006-06-01 | Microfluidic devices and methods of use |
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PCT/US2006/021380 WO2007081387A1 (en) | 2006-01-11 | 2006-06-01 | Microfluidic devices, methods of use, and kits for performing diagnostics |
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JP2006507921A (en) | 2002-06-28 | 2006-03-09 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | Method and apparatus for fluid dispersion |
GB0307403D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
AU2004229440B2 (en) | 2003-04-10 | 2010-08-12 | President And Fellows Of Harvard College | Formation and control of fluidic species |
EP1658133A1 (en) | 2003-08-27 | 2006-05-24 | President And Fellows Of Harvard College | Electronic control of fluidic species |
US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
US9477233B2 (en) | 2004-07-02 | 2016-10-25 | The University Of Chicago | Microfluidic system with a plurality of sequential T-junctions for performing reactions in microdroplets |
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