WO2007089393A3 - Treatment of reproductive endocrine disorders by vagus nerve stimulation - Google Patents

Treatment of reproductive endocrine disorders by vagus nerve stimulation Download PDF

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Publication number
WO2007089393A3
WO2007089393A3 PCT/US2007/000342 US2007000342W WO2007089393A3 WO 2007089393 A3 WO2007089393 A3 WO 2007089393A3 US 2007000342 W US2007000342 W US 2007000342W WO 2007089393 A3 WO2007089393 A3 WO 2007089393A3
Authority
WO
WIPO (PCT)
Prior art keywords
reproductive endocrine
treatment
endocrine disorders
nerve stimulation
vagus nerve
Prior art date
Application number
PCT/US2007/000342
Other languages
French (fr)
Other versions
WO2007089393A2 (en
Inventor
William R Buras
Original Assignee
Cyberonics Inc
William R Buras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cyberonics Inc, William R Buras filed Critical Cyberonics Inc
Priority to EP07763003A priority Critical patent/EP1993661A2/en
Publication of WO2007089393A2 publication Critical patent/WO2007089393A2/en
Publication of WO2007089393A3 publication Critical patent/WO2007089393A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/3615—Intensity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset

Abstract

I disclose a method of treating a reproductive endocrine disorder in a patient, including coupling at least one electrode to at least one portion of a cranial nerve of the patient; and applying an electrical signal to said cranial nerve using said electrode to treat said reproductive endocrine disorder. Among the reproductive endocrine disorders which may be treated by the method are gonadal dysgenesis, hypogonadism, hypergonadism, delayed puberty, amenorrhea, infertility, premature menopause, and polycystic ovarian disease.
PCT/US2007/000342 2006-01-26 2007-01-09 Treatment of reproductive endocrine disorders by vagus nerve stimulation WO2007089393A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07763003A EP1993661A2 (en) 2006-01-26 2007-01-09 Treatment of reproductive endocrine disorders by vagus nerve stimulation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/340,309 2006-01-26
US11/340,309 US7657310B2 (en) 2006-01-26 2006-01-26 Treatment of reproductive endocrine disorders by vagus nerve stimulation

Publications (2)

Publication Number Publication Date
WO2007089393A2 WO2007089393A2 (en) 2007-08-09
WO2007089393A3 true WO2007089393A3 (en) 2007-10-25

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/000342 WO2007089393A2 (en) 2006-01-26 2007-01-09 Treatment of reproductive endocrine disorders by vagus nerve stimulation

Country Status (3)

Country Link
US (1) US7657310B2 (en)
EP (1) EP1993661A2 (en)
WO (1) WO2007089393A2 (en)

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