WO2008055157A3 - Circular polarization illumination based analyzer system - Google Patents
Circular polarization illumination based analyzer system Download PDFInfo
- Publication number
- WO2008055157A3 WO2008055157A3 PCT/US2007/083004 US2007083004W WO2008055157A3 WO 2008055157 A3 WO2008055157 A3 WO 2008055157A3 US 2007083004 W US2007083004 W US 2007083004W WO 2008055157 A3 WO2008055157 A3 WO 2008055157A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- light
- angle scattered
- circular polarization
- detected
- analyzer system
- Prior art date
Links
- 230000010287 polarization Effects 0.000 title abstract 2
- 238000005286 illumination Methods 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 3
- 230000000644 propagated effect Effects 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1404—Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/21—Polarisation-affecting properties
-
- G01N2015/016—
-
- G01N2015/1027—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1404—Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
- G01N2015/1413—Hydrodynamic focussing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N2015/1477—Multiparameters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N2015/1486—Counting the particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N2015/1493—Particle size
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N2021/4704—Angular selective
- G01N2021/4707—Forward scatter; Low angle scatter
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N2021/4792—Polarisation of scatter light
Abstract
A particle discriminator using circularly polarized light projected through a channel having target particles. Light may be propagated through the channel, with some light scattered separated into forward angle scattered light, small angle scattered light and unscattered light. The forward angle scattered light may be linearly polarized and detected. The small angle scattered light may be linearly polarized in a direction orthogonal to the direction of the polarization of the forward angle scattered light, and at least both these kinds of light may be detected. Data from these detected kinds of light may be analyzed to discriminate particles from one another.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/554,878 US7630075B2 (en) | 2004-09-27 | 2006-10-31 | Circular polarization illumination based analyzer system |
US11/554,878 | 2006-10-31 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008055157A2 WO2008055157A2 (en) | 2008-05-08 |
WO2008055157A3 true WO2008055157A3 (en) | 2008-06-26 |
Family
ID=39204975
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/083004 WO2008055157A2 (en) | 2006-10-31 | 2007-10-30 | Circular polarization illumination based analyzer system |
Country Status (2)
Country | Link |
---|---|
US (1) | US7630075B2 (en) |
WO (1) | WO2008055157A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7956998B2 (en) * | 2007-09-04 | 2011-06-07 | James Plant | Method and system for the polarmetric analysis of scattering media utilising polarization difference sensing (PDS) |
US8654332B2 (en) * | 2011-06-22 | 2014-02-18 | Teledyne Scientific & Imaging, Llc | Chip-scale optics module for optical interrogators |
JP6196502B2 (en) * | 2013-08-30 | 2017-09-13 | シスメックス株式会社 | Sample analysis method and sample analyzer |
GB201509926D0 (en) * | 2015-06-08 | 2015-07-22 | Univ Hertfordshire Higher Education Corp | Crystalline particle detection |
KR101658874B1 (en) * | 2015-08-03 | 2016-09-22 | 부경대학교 산학협력단 | Apparatus for discriminating bacteria types using optical scattering patterns |
WO2017078672A1 (en) * | 2015-11-02 | 2017-05-11 | Chiranjit Deka | Light scatter based apparatus and methods for hematology analysis using only three detectors |
US20230266227A1 (en) * | 2020-06-03 | 2023-08-24 | Kinetic River Corp. | Configurable particle analyzer apparatuses and methods |
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Also Published As
Publication number | Publication date |
---|---|
WO2008055157A2 (en) | 2008-05-08 |
US7630075B2 (en) | 2009-12-08 |
US20070058252A1 (en) | 2007-03-15 |
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