WO2008091712A3 - Low field electron paramagnetic resonance imaging with squid detection - Google Patents

Low field electron paramagnetic resonance imaging with squid detection Download PDF

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Publication number
WO2008091712A3
WO2008091712A3 PCT/US2008/001136 US2008001136W WO2008091712A3 WO 2008091712 A3 WO2008091712 A3 WO 2008091712A3 US 2008001136 W US2008001136 W US 2008001136W WO 2008091712 A3 WO2008091712 A3 WO 2008091712A3
Authority
WO
WIPO (PCT)
Prior art keywords
squid
resonance imaging
low field
field electron
paramagnetic resonance
Prior art date
Application number
PCT/US2008/001136
Other languages
French (fr)
Other versions
WO2008091712A2 (en
Inventor
Inseob Hanh
Peter Day
Konstantin I Penanen
Byeong H Eom
Mark S Cohen
Original Assignee
California Inst Of Techn
Inseob Hanh
Peter Day
Konstantin I Penanen
Byeong H Eom
Mark S Cohen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Inst Of Techn, Inseob Hanh, Peter Day, Konstantin I Penanen, Byeong H Eom, Mark S Cohen filed Critical California Inst Of Techn
Publication of WO2008091712A2 publication Critical patent/WO2008091712A2/en
Publication of WO2008091712A3 publication Critical patent/WO2008091712A3/en
Priority to US12/359,576 priority Critical patent/US8179135B2/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
    • G01R33/323—Detection of MR without the use of RF or microwaves, e.g. force-detected MR, thermally detected MR, MR detection via electrical conductivity, optically detected MR
    • G01R33/326—Detection of MR without the use of RF or microwaves, e.g. force-detected MR, thermally detected MR, MR detection via electrical conductivity, optically detected MR involving a SQUID
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
    • G01N24/10—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using electron paramagnetic resonance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/02—Measuring direction or magnitude of magnetic fields or magnetic flux
    • G01R33/035—Measuring direction or magnitude of magnetic fields or magnetic flux using superconductive devices
    • G01R33/0354—SQUIDS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/02—Measuring direction or magnitude of magnetic fields or magnetic flux
    • G01R33/035—Measuring direction or magnitude of magnetic fields or magnetic flux using superconductive devices
    • G01R33/0354—SQUIDS
    • G01R33/0358—SQUIDS coupling the flux to the SQUID
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/445—MR involving a non-standard magnetic field B0, e.g. of low magnitude as in the earth's magnetic field or in nanoTesla spectroscopy, comprising a polarizing magnetic field for pre-polarisation, B0 with a temporal variation of its magnitude or direction such as field cycling of B0 or rotation of the direction of B0, or spatially inhomogeneous B0 like in fringe-field MR or in stray-field imaging

Abstract

A flux transformer is magnetically coupled to a SQUID (112), and a plurality of SQUIDs (114B1 115B, 116B, 117B), connected in series, is magnetically coupled to the output of the SQUID. Alternatively, a flux transformer (108, 110) and a modulating coil (330) are magnetically coupled to a SQUID and an oscillator drives the modulating coil (230) at a frequency f. A processing system (306) mixes the output signal of the SQUID with sin(wt) and cos(2wt), where w = 2TT.f.
PCT/US2008/001136 2007-01-25 2008-01-28 Low field electron paramagnetic resonance imaging with squid detection WO2008091712A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/359,576 US8179135B2 (en) 2008-01-28 2009-01-26 Low field electron paramagnetic resonance imaging with SQUID detection

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89735607P 2007-01-25 2007-01-25
US60/897,356 2007-01-25

Publications (2)

Publication Number Publication Date
WO2008091712A2 WO2008091712A2 (en) 2008-07-31
WO2008091712A3 true WO2008091712A3 (en) 2008-11-06

Family

ID=39422394

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/001136 WO2008091712A2 (en) 2007-01-25 2008-01-28 Low field electron paramagnetic resonance imaging with squid detection

Country Status (1)

Country Link
WO (1) WO2008091712A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9529035B2 (en) * 2011-11-14 2016-12-27 Neocera, Llc Method and system for localization of open defects in electronic devices with a DC squid based RF magnetometer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5885215A (en) * 1989-07-06 1999-03-23 U.S. Philips Corporation Method of reconstructing the spatial current distribution in a biological object, and device for performing the method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5885215A (en) * 1989-07-06 1999-03-23 U.S. Philips Corporation Method of reconstructing the spatial current distribution in a biological object, and device for performing the method

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHUI T ET AL: "High-resolution displacement sensor using SQUID array amplifier", NUCLEAR PHYSICS B. PROCEEDINGS SUPPLEMENT, NORTH-HOLLAND, AMSTERDAM, NL, vol. 134, 1 September 2004 (2004-09-01), pages 214 - 216, XP004573801, ISSN: 0920-5632 *
MCDERMOTT R ET AL: "SQUID-Detected Magnetic Resonance Imaging in Microtesla Magnetic Fields", JOURNAL OF LOW TEMPERATURE PHYSICS, KLUWER ACADEMIC PUBLISHERS-CONSULTANTS BUREAU, NE, vol. 135, no. 5-6, 1 June 2004 (2004-06-01), pages 793 - 821, XP019282681, ISSN: 1573-7357 *
WELTY R P ET AL: "Two-stage integrated SQUID amplifier with series array output", IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY USA, vol. 3, no. 1, March 1993 (1993-03-01), pages 2605 - 2608, XP002482165, ISSN: 1051-8223 *

Also Published As

Publication number Publication date
WO2008091712A2 (en) 2008-07-31

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