WO2008092119A3 - Systems and methods for identifying a contra-ictal condition in a subject - Google Patents

Systems and methods for identifying a contra-ictal condition in a subject Download PDF

Info

Publication number
WO2008092119A3
WO2008092119A3 PCT/US2008/052115 US2008052115W WO2008092119A3 WO 2008092119 A3 WO2008092119 A3 WO 2008092119A3 US 2008052115 W US2008052115 W US 2008052115W WO 2008092119 A3 WO2008092119 A3 WO 2008092119A3
Authority
WO
WIPO (PCT)
Prior art keywords
subject
contra
ictal condition
condition
ictal
Prior art date
Application number
PCT/US2008/052115
Other languages
French (fr)
Other versions
WO2008092119A2 (en
Inventor
David Snyder
Kent W Leyde
John F Harris
Original Assignee
Neurovista Corp
David Snyder
Kent W Leyde
John F Harris
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurovista Corp, David Snyder, Kent W Leyde, John F Harris filed Critical Neurovista Corp
Priority to EP08728338A priority Critical patent/EP2126785A2/en
Publication of WO2008092119A2 publication Critical patent/WO2008092119A2/en
Publication of WO2008092119A3 publication Critical patent/WO2008092119A3/en

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/30—Unsupervised data analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/369—Electroencephalography [EEG]
    • A61B5/372—Analysis of electroencephalograms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/369—Electroencephalography [EEG]
    • A61B5/375—Electroencephalography [EEG] using biofeedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4094—Diagnosing or monitoring seizure diseases, e.g. epilepsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A61B5/0006—ECG or EEG signals
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F2218/00—Aspects of pattern recognition specially adapted for signal processing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

The invention provides a method of monitoring a subject's neurological condition. In some embodiments, the method includes the steps of analyzing a physiological signal (such as an EEG) from a subject to determine if the subject is in a contra-ictal condition; and if the subject is in a contra-ictal condition, providing an indication (e.g., to the subject and/or to a caregiver) that the subject is in the contra-ictal condition, such as by activating a green light or other visible output. In some embodiments, if the subject is in a pro-ictal condition, the method includes the step of providing an indication (such as a red light) that the subject is in the pro-ictal condition. The invention also provides neurological system monitors.
PCT/US2008/052115 2007-01-25 2008-01-25 Systems and methods for identifying a contra-ictal condition in a subject WO2008092119A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP08728338A EP2126785A2 (en) 2007-01-25 2008-01-25 Systems and methods for identifying a contra-ictal condition in a subject

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89754907P 2007-01-25 2007-01-25
US60/897,549 2007-01-25

Publications (2)

Publication Number Publication Date
WO2008092119A2 WO2008092119A2 (en) 2008-07-31
WO2008092119A3 true WO2008092119A3 (en) 2008-10-09

Family

ID=39592795

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/052115 WO2008092119A2 (en) 2007-01-25 2008-01-25 Systems and methods for identifying a contra-ictal condition in a subject

Country Status (3)

Country Link
US (1) US9898656B2 (en)
EP (1) EP2126785A2 (en)
WO (1) WO2008092119A2 (en)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7747325B2 (en) 1998-08-05 2010-06-29 Neurovista Corporation Systems and methods for monitoring a patient's neurological disease state
US9050469B1 (en) 2003-11-26 2015-06-09 Flint Hills Scientific, Llc Method and system for logging quantitative seizure information and assessing efficacy of therapy using cardiac signals
US9314633B2 (en) 2008-01-25 2016-04-19 Cyberonics, Inc. Contingent cardio-protection for epilepsy patients
US8260426B2 (en) 2008-01-25 2012-09-04 Cyberonics, Inc. Method, apparatus and system for bipolar charge utilization during stimulation by an implantable medical device
US8565867B2 (en) 2005-01-28 2013-10-22 Cyberonics, Inc. Changeable electrode polarity stimulation by an implantable medical device
US8725243B2 (en) 2005-12-28 2014-05-13 Cyberonics, Inc. Methods and systems for recommending an appropriate pharmacological treatment to a patient for managing epilepsy and other neurological disorders
US7996079B2 (en) 2006-01-24 2011-08-09 Cyberonics, Inc. Input response override for an implantable medical device
ES2538726T3 (en) 2006-03-29 2015-06-23 Dignity Health Vagus nerve stimulation system
US7869885B2 (en) 2006-04-28 2011-01-11 Cyberonics, Inc Threshold optimization for tissue stimulation therapy
US7962220B2 (en) 2006-04-28 2011-06-14 Cyberonics, Inc. Compensation reduction in tissue stimulation therapy
US7869867B2 (en) * 2006-10-27 2011-01-11 Cyberonics, Inc. Implantable neurostimulator with refractory stimulation
US20080183097A1 (en) 2007-01-25 2008-07-31 Leyde Kent W Methods and Systems for Measuring a Subject's Susceptibility to a Seizure
US8036736B2 (en) 2007-03-21 2011-10-11 Neuro Vista Corporation Implantable systems and methods for identifying a contra-ictal condition in a subject
US7974701B2 (en) 2007-04-27 2011-07-05 Cyberonics, Inc. Dosing limitation for an implantable medical device
US9788744B2 (en) * 2007-07-27 2017-10-17 Cyberonics, Inc. Systems for monitoring brain activity and patient advisory device
US9259591B2 (en) 2007-12-28 2016-02-16 Cyberonics, Inc. Housing for an implantable medical device
US20090171168A1 (en) 2007-12-28 2009-07-02 Leyde Kent W Systems and Method for Recording Clinical Manifestations of a Seizure
US8337404B2 (en) 2010-10-01 2012-12-25 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US8382667B2 (en) 2010-10-01 2013-02-26 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US8571643B2 (en) 2010-09-16 2013-10-29 Flint Hills Scientific, Llc Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex
US8204603B2 (en) 2008-04-25 2012-06-19 Cyberonics, Inc. Blocking exogenous action potentials by an implantable medical device
US9443141B2 (en) * 2008-06-02 2016-09-13 New York University Method, system, and computer-accessible medium for classification of at least one ICTAL state
US8457747B2 (en) 2008-10-20 2013-06-04 Cyberonics, Inc. Neurostimulation with signal duration determined by a cardiac cycle
US8417344B2 (en) 2008-10-24 2013-04-09 Cyberonics, Inc. Dynamic cranial nerve stimulation based on brain state determination from cardiac data
US8849390B2 (en) 2008-12-29 2014-09-30 Cyberonics, Inc. Processing for multi-channel signals
US8588933B2 (en) 2009-01-09 2013-11-19 Cyberonics, Inc. Medical lead termination sleeve for implantable medical devices
US20100191304A1 (en) 2009-01-23 2010-07-29 Scott Timothy L Implantable Medical Device for Providing Chronic Condition Therapy and Acute Condition Therapy Using Vagus Nerve Stimulation
US8239028B2 (en) 2009-04-24 2012-08-07 Cyberonics, Inc. Use of cardiac parameters in methods and systems for treating a chronic medical condition
US8827912B2 (en) 2009-04-24 2014-09-09 Cyberonics, Inc. Methods and systems for detecting epileptic events using NNXX, optionally with nonlinear analysis parameters
US8786624B2 (en) * 2009-06-02 2014-07-22 Cyberonics, Inc. Processing for multi-channel signals
JP5395954B2 (en) * 2009-06-26 2014-01-22 ヴェーデクス・アクティーセルスカプ EEG monitoring system and method for monitoring EEG
US9643019B2 (en) 2010-02-12 2017-05-09 Cyberonics, Inc. Neurological monitoring and alerts
US20110218820A1 (en) 2010-03-02 2011-09-08 Himes David M Displaying and Manipulating Brain Function Data Including Filtering of Annotations
US20110219325A1 (en) 2010-03-02 2011-09-08 Himes David M Displaying and Manipulating Brain Function Data Including Enhanced Data Scrolling Functionality
US8831732B2 (en) 2010-04-29 2014-09-09 Cyberonics, Inc. Method, apparatus and system for validating and quantifying cardiac beat data quality
US8649871B2 (en) 2010-04-29 2014-02-11 Cyberonics, Inc. Validity test adaptive constraint modification for cardiac data used for detection of state changes
US8562536B2 (en) 2010-04-29 2013-10-22 Flint Hills Scientific, Llc Algorithm for detecting a seizure from cardiac data
US8679009B2 (en) 2010-06-15 2014-03-25 Flint Hills Scientific, Llc Systems approach to comorbidity assessment
US8641646B2 (en) 2010-07-30 2014-02-04 Cyberonics, Inc. Seizure detection using coordinate data
US8562524B2 (en) 2011-03-04 2013-10-22 Flint Hills Scientific, Llc Detecting, assessing and managing a risk of death in epilepsy
US8684921B2 (en) 2010-10-01 2014-04-01 Flint Hills Scientific Llc Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis
US8562523B2 (en) 2011-03-04 2013-10-22 Flint Hills Scientific, Llc Detecting, assessing and managing extreme epileptic events
WO2012095171A1 (en) * 2011-01-12 2012-07-19 Widex A/S Bi-hemispheric brain wave system and method of performing bi-hemispherical brain wave measurements
US9504390B2 (en) 2011-03-04 2016-11-29 Globalfoundries Inc. Detecting, assessing and managing a risk of death in epilepsy
US9498162B2 (en) 2011-04-25 2016-11-22 Cyberonics, Inc. Identifying seizures using heart data from two or more windows
US9402550B2 (en) 2011-04-29 2016-08-02 Cybertronics, Inc. Dynamic heart rate threshold for neurological event detection
US9549677B2 (en) 2011-10-14 2017-01-24 Flint Hills Scientific, L.L.C. Seizure detection methods, apparatus, and systems using a wavelet transform maximum modulus algorithm
US10448839B2 (en) 2012-04-23 2019-10-22 Livanova Usa, Inc. Methods, systems and apparatuses for detecting increased risk of sudden death
WO2014027962A1 (en) * 2012-08-14 2014-02-20 Nanyang Technological University Device, system and method for detection of fluid accumulation
CN102940490B (en) * 2012-10-19 2014-06-18 西安电子科技大学 Method for extracting motor imagery electroencephalogram signal feature based on non-linear dynamics
US10220211B2 (en) 2013-01-22 2019-03-05 Livanova Usa, Inc. Methods and systems to diagnose depression
WO2015089659A1 (en) * 2013-12-16 2015-06-25 Inbubbles Inc. Space time region based communications
US11504038B2 (en) * 2016-02-12 2022-11-22 Newton Howard Early detection of neurodegenerative disease
US20170258390A1 (en) * 2016-02-12 2017-09-14 Newton Howard Early Detection Of Neurodegenerative Disease
US20190254599A1 (en) * 2018-02-02 2019-08-22 Sentier Hc Llc Systems and methods for non-invasive monitoring of animals
US11517239B2 (en) 2018-04-05 2022-12-06 Cadwell Laboratories, Inc. Systems and methods for processing and displaying electromyographic signals
US11596337B2 (en) 2018-04-24 2023-03-07 Cadwell Laboratories, Inc Methods and systems for operating an intraoperative neurophysiological monitoring system in conjunction with electrocautery procedures
US11185684B2 (en) 2018-09-18 2021-11-30 Cadwell Laboratories, Inc. Minimally invasive two-dimensional grid electrode
ES2752273A1 (en) * 2018-10-03 2020-04-03 Mjn Neuroserveis S L Method and device for real-time monitoring and evaluation of the condition of a patient with a neurological condition (Machine-translation by Google Translate, not legally binding)
US11517245B2 (en) 2018-10-30 2022-12-06 Cadwell Laboratories, Inc. Method and system for data synchronization
US11471087B2 (en) 2018-11-09 2022-10-18 Cadwell Laboratories, Inc. Integrity verification system for testing high channel count neuromonitoring recording equipment
US11317841B2 (en) 2018-11-14 2022-05-03 Cadwell Laboratories, Inc. Method and system for electrode verification
US11529107B2 (en) 2018-11-27 2022-12-20 Cadwell Laboratories, Inc. Methods for automatic generation of EEG montages
US11128076B2 (en) 2019-01-21 2021-09-21 Cadwell Laboratories, Inc. Connector receptacle

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002049500A2 (en) * 2000-12-12 2002-06-27 The Trustees Of The University Of Pennsylvania Forecasting and controlling neurological disturbances
WO2002058536A2 (en) * 2000-10-20 2002-08-01 The Trustees Of The University Of Pennsylvania Predicting and detecting seizure onsets
US20050124863A1 (en) * 2001-06-28 2005-06-09 Cook Daniel R. Drug profiling apparatus and method

Family Cites Families (463)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3218638A (en) 1962-05-29 1965-11-16 William M Honig Wireless passive biological telemetry system
US3498287A (en) 1966-04-28 1970-03-03 Neural Models Ltd Intelligence testing and signal analyzing means and method employing zero crossing detection
US3575162A (en) 1968-12-23 1971-04-20 Kenneth R Gaarder Physiological monitors and method of using the same in treatment of disease
US3522811A (en) 1969-02-13 1970-08-04 Medtronic Inc Implantable nerve stimulator and method of use
US3837331A (en) 1972-10-24 1974-09-24 S Ross System and method for controlling the nervous system of a living organism
US3967616A (en) 1972-10-24 1976-07-06 Ross Sidney A Multichannel system for and a multifactorial method of controlling the nervous system of a living organism
US3850161A (en) 1973-04-09 1974-11-26 S Liss Method and apparatus for monitoring and counteracting excess brain electrical energy to prevent epileptic seizures and the like
US3882850A (en) 1973-05-09 1975-05-13 Howard Bailin Brain wave feedback instrument
US3863625A (en) 1973-11-02 1975-02-04 Us Health Epileptic seizure warning system
US3918461A (en) 1974-01-31 1975-11-11 Irving S Cooper Method for electrically stimulating the human brain
US3993046A (en) 1974-11-06 1976-11-23 Heriberto Fernandez Seizure suppression device
US4505275A (en) 1977-09-15 1985-03-19 Wu Chen Treatment method and instrumentation system
JPS587291B2 (en) 1977-10-08 1983-02-09 財団法人交通医学研究財団 Automatic brain wave determination device
JPS5573269A (en) 1978-11-28 1980-06-02 Matsushita Electric Ind Co Ltd Living body feedback device
US4201224A (en) 1978-12-29 1980-05-06 Roy John E Electroencephalographic method and system for the quantitative description of patient brain states
US4305402A (en) 1979-06-29 1981-12-15 Katims Jefferson J Method for transcutaneous electrical stimulation
US4279258A (en) 1980-03-26 1981-07-21 Roy John E Rapid automatic electroencephalographic evaluation
JPS57177735A (en) 1981-04-27 1982-11-01 Toyoda Chuo Kenkyusho Kk Telemeter type brain nanometer
US4421122A (en) 1981-05-15 1983-12-20 The Children's Medical Center Corporation Brain electrical activity mapping
US4407299A (en) 1981-05-15 1983-10-04 The Children's Medical Center Corporation Brain electrical activity mapping
USRE34015E (en) 1981-05-15 1992-08-04 The Children's Medical Center Corporation Brain electrical activity mapping
US4408616A (en) 1981-05-15 1983-10-11 The Children's Medical Center Corporation Brain electricaL activity mapping
US4793353A (en) 1981-06-30 1988-12-27 Borkan William N Non-invasive multiprogrammable tissue stimulator and method
US4612934A (en) 1981-06-30 1986-09-23 Borkan William N Non-invasive multiprogrammable tissue stimulator
US4566464A (en) 1981-07-27 1986-01-28 Piccone Vincent A Implantable epilepsy monitor apparatus
SU1074484A1 (en) 1981-08-19 1984-02-23 Ленинградский Нейрохирургический Институт Им.Проф.А.Л.Поленова Method of diagnosis of epilepsia
US4494950A (en) 1982-01-19 1985-01-22 The Johns Hopkins University Plural module medication delivery system
US4556061A (en) 1982-08-18 1985-12-03 Cordis Corporation Cardiac pacer with battery consumption monitor circuit
EP0124663A1 (en) 1983-05-04 1984-11-14 General Foods Corporation Compressed tablets
US4545388A (en) 1983-06-09 1985-10-08 Roy John E Self-normed brain state monitoring
US4867164A (en) 1983-09-14 1989-09-19 Jacob Zabara Neurocybernetic prosthesis
EP0156854B1 (en) 1983-09-14 1990-09-05 ZABARA, Jacob Neurocybernetic prosthesis
US5025807A (en) 1983-09-14 1991-06-25 Jacob Zabara Neurocybernetic prosthesis
US4702254A (en) 1983-09-14 1987-10-27 Jacob Zabara Neurocybernetic prosthesis
US4844075A (en) 1984-01-09 1989-07-04 Pain Suppression Labs, Inc. Transcranial stimulation for the treatment of cerebral palsy
US4579125A (en) 1984-01-23 1986-04-01 Cns, Inc. Real-time EEG spectral analyzer
US4590946A (en) 1984-06-14 1986-05-27 Biomed Concepts, Inc. Surgically implantable electrode for nerve bundles
US4573481A (en) 1984-06-25 1986-03-04 Huntington Institute Of Applied Research Implantable electrode array
US4768176A (en) 1984-07-06 1988-08-30 Kehr Bruce A Apparatus for alerting a patient to take medication
US4768177A (en) 1984-07-06 1988-08-30 Kehr Bruce A Method of and apparatus for alerting a patient to take medication
US4679144A (en) * 1984-08-21 1987-07-07 Q-Med, Inc. Cardiac signal real time monitor and method of analysis
US4934372A (en) * 1985-04-01 1990-06-19 Nellcor Incorporated Method and apparatus for detecting optical pulses
US4686999A (en) * 1985-04-10 1987-08-18 Tri Fund Research Corporation Multi-channel ventilation monitor and method
US4817628A (en) 1985-10-18 1989-04-04 David L. Zealear System and method for evaluating neurological function controlling muscular movements
US5167229A (en) 1986-03-24 1992-12-01 Case Western Reserve University Functional neuromuscular stimulation system
US4735208B1 (en) * 1987-01-09 1995-07-04 Ad Tech Medical Instr Corp Subdural strip electrode for determining epileptogenic foci
US4785827A (en) * 1987-01-28 1988-11-22 Minnesota Mining And Manufacturing Company Subcutaneous housing assembly
US5070873A (en) 1987-02-13 1991-12-10 Sigmedics, Inc. Method of and apparatus for electrically stimulating quadriceps muscles of an upper motor unit paraplegic
US5047930A (en) * 1987-06-26 1991-09-10 Nicolet Instrument Corporation Method and system for analysis of long term physiological polygraphic recordings
US4838272A (en) 1987-08-19 1989-06-13 The Regents Of The University Of California Method and apparatus for adaptive closed loop electrical stimulation of muscles
US4926865A (en) 1987-10-01 1990-05-22 Oman Paul S Microcomputer-based nerve and muscle stimulator
US5010891A (en) 1987-10-09 1991-04-30 Biometrak Corporation Cerebral biopotential analysis system and method
US5871472A (en) 1987-11-17 1999-02-16 Brown University Research Foundation Planting devices for the focal release of neuroinhibitory compounds
US4852573A (en) 1987-12-04 1989-08-01 Kennedy Philip R Implantable neural electrode
GB8729899D0 (en) 1987-12-22 1988-02-03 Royal Postgrad Med School Method & apparatus for analysing electro-encephalogram
US5343064A (en) 1988-03-18 1994-08-30 Spangler Leland J Fully integrated single-crystal silicon-on-insulator process, sensors and circuits
US4920979A (en) 1988-10-12 1990-05-01 Huntington Medical Research Institute Bidirectional helical electrode for nerve stimulation
US4873981A (en) 1988-10-14 1989-10-17 Somatics, Inc. Electroconvulsive therapy apparatus and method for automatic monitoring of patient seizures
US4878498A (en) 1988-10-14 1989-11-07 Somatics, Inc. Electroconvulsive therapy apparatus and method for automatic monitoring of patient seizures
US4903702A (en) * 1988-10-17 1990-02-27 Ad-Tech Medical Instrument Corporation Brain-contact for sensing epileptogenic foci with improved accuracy
US5016635A (en) 1988-11-29 1991-05-21 Sigmedics, Inc. Of Delaware Control of FNS via pattern variations of response EMG
US5766573A (en) 1988-12-06 1998-06-16 Riker Laboratories, Inc. Medicinal aerosol formulations
US4955380A (en) 1988-12-15 1990-09-11 Massachusetts Institute Of Technology Flexible measurement probes
US5697369A (en) 1988-12-22 1997-12-16 Biofield Corp. Method and apparatus for disease, injury and bodily condition screening or sensing
FR2645641B1 (en) 1989-04-10 1991-05-31 Bruno Comby METHOD AND DEVICE FOR MEASURING VIBRATION, IN PARTICULAR MICROSCOPIC SHAKING OF LIVING ORGANISMS
DE58906649D1 (en) 1989-05-22 1994-02-17 Siemens Ag Implantable medical device with means for stimulating tissue contractions with adjustable stimulation intensity and method for operating such a device.
US4991582A (en) * 1989-09-22 1991-02-12 Alfred E. Mann Foundation For Scientific Research Hermetically sealed ceramic and metal package for electronic devices implantable in living bodies
US5292772A (en) 1989-09-26 1994-03-08 Carter-Wallace, Inc. Method for the prevention and control of epileptic seizure associated with Lennox-Gastaut syndrome
US5082861A (en) 1989-09-26 1992-01-21 Carter-Wallace, Inc. Method for the prevention and control of epileptic seizure associated with complex partial seizures
US4978680A (en) 1989-09-26 1990-12-18 Carter-Wallace, Inc. Method for the prevention and control of epileptic seizure
US4979511A (en) 1989-11-03 1990-12-25 Cyberonics, Inc. Strain relief tether for implantable electrode
US5361760A (en) 1989-11-07 1994-11-08 University Of Utah Research Foundation Impact inserter mechanism for implantation of a biomedical device
US5215088A (en) 1989-11-07 1993-06-01 The University Of Utah Three-dimensional electrode device
US5154172A (en) 1989-11-13 1992-10-13 Cyberonics, Inc. Constant current sources with programmable voltage source
US5186170A (en) 1989-11-13 1993-02-16 Cyberonics, Inc. Simultaneous radio frequency and magnetic field microprocessor reset circuit
US5179950A (en) 1989-11-13 1993-01-19 Cyberonics, Inc. Implanted apparatus having micro processor controlled current and voltage sources with reduced voltage levels when not providing stimulation
US5235980A (en) 1989-11-13 1993-08-17 Cyberonics, Inc. Implanted apparatus disabling switching regulator operation to allow radio frequency signal reception
US5031618A (en) 1990-03-07 1991-07-16 Medtronic, Inc. Position-responsive neuro stimulator
US5097835A (en) 1990-04-09 1992-03-24 Ad-Tech Medical Instrument Corporation Subdural electrode with improved lead connection
US5314458A (en) 1990-06-01 1994-05-24 University Of Michigan Single channel microstimulator
IE912227A1 (en) 1990-06-28 1992-01-01 Verhoeven Jean Marie Method and device for the treatment of epilepsy
DE69209324T2 (en) 1991-01-09 1996-11-21 Medtronic Inc Servo control for muscles
US5263480A (en) 1991-02-01 1993-11-23 Cyberonics, Inc. Treatment of eating disorders by nerve stimulation
US5188104A (en) 1991-02-01 1993-02-23 Cyberonics, Inc. Treatment of eating disorders by nerve stimulation
US5190029A (en) 1991-02-14 1993-03-02 Virginia Commonwealth University Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
US5269303A (en) 1991-02-22 1993-12-14 Cyberonics, Inc. Treatment of dementia by nerve stimulation
US5222503A (en) 1991-04-24 1993-06-29 Beth Israel Hospital Association Ambulatory electroencephalography system
US5215086A (en) 1991-05-03 1993-06-01 Cyberonics, Inc. Therapeutic treatment of migraine symptoms by stimulation
US5299569A (en) 1991-05-03 1994-04-05 Cyberonics, Inc. Treatment of neuropsychiatric disorders by nerve stimulation
US5251634A (en) 1991-05-03 1993-10-12 Cyberonics, Inc. Helical nerve electrode
US5335657A (en) 1991-05-03 1994-08-09 Cyberonics, Inc. Therapeutic treatment of sleep disorder by nerve stimulation
US5269302A (en) 1991-05-10 1993-12-14 Somatics, Inc. Electroconvulsive therapy apparatus and method for monitoring patient seizures
US5205285A (en) 1991-06-14 1993-04-27 Cyberonics, Inc. Voice suppression of vagal stimulation
US5222494A (en) 1991-07-31 1993-06-29 Cyberonics, Inc. Implantable tissue stimulator output stabilization system
US5231988A (en) 1991-08-09 1993-08-03 Cyberonics, Inc. Treatment of endocrine disorders by nerve stimulation
US5269315A (en) 1991-08-16 1993-12-14 The Regents Of The University Of California Determining the nature of brain lesions by electroencephalography
US5293879A (en) 1991-09-23 1994-03-15 Vitatron Medical, B.V. System an method for detecting tremors such as those which result from parkinson's disease
US5215089A (en) 1991-10-21 1993-06-01 Cyberonics, Inc. Electrode assembly for nerve stimulation
US5458117A (en) 1991-10-25 1995-10-17 Aspect Medical Systems, Inc. Cerebral biopotential analysis system and method
US5304206A (en) 1991-11-18 1994-04-19 Cyberonics, Inc. Activation techniques for implantable medical device
US5237991A (en) 1991-11-19 1993-08-24 Cyberonics, Inc. Implantable medical device with dummy load for pre-implant testing in sterile package and facilitating electrical lead connection
US5312439A (en) 1991-12-12 1994-05-17 Loeb Gerald E Implantable device having an electrolytic storage electrode
US5193540A (en) 1991-12-18 1993-03-16 Alfred E. Mann Foundation For Scientific Research Structure and method of manufacture of an implantable microstimulator
US5193539A (en) 1991-12-18 1993-03-16 Alfred E. Mann Foundation For Scientific Research Implantable microstimulator
US5330515A (en) 1992-06-17 1994-07-19 Cyberonics, Inc. Treatment of pain by vagal afferent stimulation
US5376359A (en) 1992-07-07 1994-12-27 Glaxo, Inc. Method of stabilizing aerosol formulations
SE500122C2 (en) * 1992-08-27 1994-04-18 Rudolf Valentin Sillen Method and apparatus for individually controlled, adaptive medication
US5476494A (en) 1992-09-11 1995-12-19 Massachusetts Institute Of Technology Low pressure neural contact structure
CA2105781C (en) 1992-09-14 2000-07-11 Alton B. Otis, Jr. Contactless communication system
US5311876A (en) 1992-11-18 1994-05-17 The Johns Hopkins University Automatic detection of seizures using electroencephalographic signals
US6117066A (en) 1992-12-04 2000-09-12 Somatics, Inc. Prevention of seizure arising from medical magnetoictal non-convulsive stimulation therapy
US5342408A (en) 1993-01-07 1994-08-30 Incontrol, Inc. Telemetry system for an implantable cardiac device
US5392788A (en) 1993-02-03 1995-02-28 Hudspeth; William J. Method and device for interpreting concepts and conceptual thought from brainwave data and for assisting for diagnosis of brainwave disfunction
US6167304A (en) 1993-05-28 2000-12-26 Loos; Hendricus G. Pulse variability in electric field manipulation of nervous systems
US5782874A (en) 1993-05-28 1998-07-21 Loos; Hendricus G. Method and apparatus for manipulating nervous systems
US6081744A (en) 1993-05-28 2000-06-27 Loos; Hendricus G. Electric fringe field generator for manipulating nervous systems
US5411540A (en) 1993-06-03 1995-05-02 Massachusetts Institute Of Technology Method and apparatus for preferential neuron stimulation
US5649068A (en) 1993-07-27 1997-07-15 Lucent Technologies Inc. Pattern recognition system using support vectors
US5549656A (en) 1993-08-16 1996-08-27 Med Serve Group, Inc. Combination neuromuscular stimulator and electromyograph system
DE4329898A1 (en) * 1993-09-04 1995-04-06 Marcus Dr Besson Wireless medical diagnostic and monitoring device
US5365939A (en) 1993-10-15 1994-11-22 Neurotrain, L.C. Method for evaluating and treating an individual with electroencephalographic disentrainment feedback
US5349962A (en) 1993-11-30 1994-09-27 University Of Washington Method and apparatus for detecting epileptic seizures
US5578036A (en) * 1993-12-06 1996-11-26 Stone; Kevin T. Method and apparatus for fixation of bone during surgical procedures
US5517115A (en) * 1993-12-16 1996-05-14 Numar Corporation Efficient processing of NMR echo trains
US5513649A (en) 1994-03-22 1996-05-07 Sam Technology, Inc. Adaptive interference canceler for EEG movement and eye artifacts
US5486999A (en) 1994-04-20 1996-01-23 Mebane; Andrew H. Apparatus and method for categorizing health care utilization
US5769778A (en) 1994-04-22 1998-06-23 Somatics, Inc. Medical magnetic non-convulsive stimulation therapy
US5782891A (en) * 1994-06-16 1998-07-21 Medtronic, Inc. Implantable ceramic enclosure for pacing, neurological, and other medical applications in the human body
US6249703B1 (en) 1994-07-08 2001-06-19 Medtronic, Inc. Handheld patient programmer for implantable human tissue stimulator
US5571148A (en) * 1994-08-10 1996-11-05 Loeb; Gerald E. Implantable multichannel stimulator
US6009061A (en) * 1994-08-25 1999-12-28 Discovision Associates Cartridge-loading apparatus with improved base plate and cartridge receiver latch
US5941106A (en) 1994-08-26 1999-08-24 Northwind Industries, Inc. Electronic remote controlled lock
US5531778A (en) 1994-09-20 1996-07-02 Cyberonics, Inc. Circumneural electrode assembly
US5540734A (en) 1994-09-28 1996-07-30 Zabara; Jacob Cranial nerve stimulation treatments using neurocybernetic prosthesis
US5555191A (en) 1994-10-12 1996-09-10 Trustees Of Columbia University In The City Of New York Automated statistical tracker
US5571150A (en) 1994-12-19 1996-11-05 Cyberonics, Inc. Treatment of patients in coma by nerve stimulation
US5638826A (en) 1995-06-01 1997-06-17 Health Research, Inc. Communication method and system using brain waves for multidimensional control
US5540730A (en) 1995-06-06 1996-07-30 Cyberonics, Inc. Treatment of motility disorders by nerve stimulation
HUP9700322A3 (en) 1995-06-09 2001-03-28 Euro Celtique Sa Formulations and methods for providing prolonged local anesthesia
GB9511964D0 (en) 1995-06-13 1995-08-09 Rdm Consultants Limited Monitoring an EEG
US5626627A (en) 1995-07-27 1997-05-06 Duke University Electroconvulsive therapy method using ICTAL EEG data as an indicator of ECT seizure adequacy
US5707400A (en) 1995-09-19 1998-01-13 Cyberonics, Inc. Treating refractory hypertension by nerve stimulation
US5700282A (en) 1995-10-13 1997-12-23 Zabara; Jacob Heart rhythm stabilization using a neurocybernetic prosthesis
US6480743B1 (en) 2000-04-05 2002-11-12 Neuropace, Inc. System and method for adaptive brain stimulation
US20020169485A1 (en) * 1995-10-16 2002-11-14 Neuropace, Inc. Differential neurostimulation therapy driven by physiological context
US6944501B1 (en) 2000-04-05 2005-09-13 Neurospace, Inc. Neurostimulator involving stimulation strategies and process for using it
US5704352A (en) * 1995-11-22 1998-01-06 Tremblay; Gerald F. Implantable passive bio-sensor
US5683432A (en) * 1996-01-11 1997-11-04 Medtronic, Inc. Adaptive, performance-optimizing communication system for communicating with an implanted medical device
US5995868A (en) 1996-01-23 1999-11-30 University Of Kansas System for the prediction, rapid detection, warning, prevention, or control of changes in activity states in the brain of a subject
US6463328B1 (en) 1996-02-02 2002-10-08 Michael Sasha John Adaptive brain stimulation method and system
US6066163A (en) 1996-02-02 2000-05-23 John; Michael Sasha Adaptive brain stimulation method and system
US5611350A (en) 1996-02-08 1997-03-18 John; Michael S. Method and apparatus for facilitating recovery of patients in deep coma
US6051017A (en) 1996-02-20 2000-04-18 Advanced Bionics Corporation Implantable microstimulator and systems employing the same
US5857978A (en) 1996-03-20 1999-01-12 Lockheed Martin Energy Systems, Inc. Epileptic seizure prediction by non-linear methods
US5743860A (en) 1996-03-20 1998-04-28 Lockheed Martin Energy Systems, Inc. Apparatus and method for epileptic seizure detection using non-linear techniques
US5626145A (en) 1996-03-20 1997-05-06 Lockheed Martin Energy Systems, Inc. Method and apparatus for extraction of low-frequency artifacts from brain waves for alertness detection
US5690681A (en) 1996-03-29 1997-11-25 Purdue Research Foundation Method and apparatus using vagal stimulation for control of ventricular rate during atrial fibrillation
US5813993A (en) 1996-04-05 1998-09-29 Consolidated Research Of Richmond, Inc. Alertness and drowsiness detection and tracking system
US5824021A (en) 1996-04-25 1998-10-20 Medtronic Inc. Method and apparatus for providing feedback to spinal cord stimulation for angina
US5716377A (en) 1996-04-25 1998-02-10 Medtronic, Inc. Method of treating movement disorders by brain stimulation
US5683422A (en) 1996-04-25 1997-11-04 Medtronic, Inc. Method and apparatus for treating neurodegenerative disorders by electrical brain stimulation
US6094598A (en) 1996-04-25 2000-07-25 Medtronics, Inc. Method of treating movement disorders by brain stimulation and drug infusion
US6006134A (en) 1998-04-30 1999-12-21 Medtronic, Inc. Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers
US5711316A (en) 1996-04-30 1998-01-27 Medtronic, Inc. Method of treating movement disorders by brain infusion
US5735814A (en) 1996-04-30 1998-04-07 Medtronic, Inc. Techniques of treating neurodegenerative disorders by brain infusion
US5709214A (en) 1996-05-02 1998-01-20 Enhanced Cardiology, Inc. PD2i electrophysiological analyzer
US5690691A (en) 1996-05-08 1997-11-25 The Center For Innovative Technology Gastro-intestinal pacemaker having phased multi-point stimulation
US5713923A (en) 1996-05-13 1998-02-03 Medtronic, Inc. Techniques for treating epilepsy by brain stimulation and drug infusion
US6104956A (en) 1996-05-31 2000-08-15 Board Of Trustees Of Southern Illinois University Methods of treating traumatic brain injury by vagus nerve stimulation
US5782798A (en) 1996-06-26 1998-07-21 Medtronic, Inc. Techniques for treating eating disorders by brain stimulation and drug infusion
DE19645371C1 (en) * 1996-10-23 1997-12-18 Biotronik Mess & Therapieg Implant, e.g. heart pacemaker, for mounting in human tissue
US5752979A (en) 1996-11-01 1998-05-19 Medtronic, Inc. Method of controlling epilepsy by brain stimulation
US5800474A (en) 1996-11-01 1998-09-01 Medtronic, Inc. Method of controlling epilepsy by brain stimulation
US7630757B2 (en) 1997-01-06 2009-12-08 Flint Hills Scientific Llc System for the prediction, rapid detection, warning, prevention, or control of changes in activity states in the brain of a subject
US6070098A (en) 1997-01-11 2000-05-30 Circadian Technologies, Inc. Method of and apparatus for evaluation and mitigation of microsleep events
US5876424A (en) * 1997-01-23 1999-03-02 Cardiac Pacemakers, Inc. Ultra-thin hermetic enclosure for implantable medical devices
US5957861A (en) * 1997-01-31 1999-09-28 Medtronic, Inc. Impedance monitor for discerning edema through evaluation of respiratory rate
US5950632A (en) 1997-03-03 1999-09-14 Motorola, Inc. Medical communication apparatus, system, and method
US7111009B1 (en) 1997-03-14 2006-09-19 Microsoft Corporation Interactive playlist generation using annotations
US6042579A (en) 1997-04-30 2000-03-28 Medtronic, Inc. Techniques for treating neurodegenerative disorders by infusion of nerve growth factors into the brain
US6128537A (en) 1997-05-01 2000-10-03 Medtronic, Inc Techniques for treating anxiety by brain stimulation and drug infusion
US5975085A (en) 1997-05-01 1999-11-02 Medtronic, Inc. Method of treating schizophrenia by brain stimulation and drug infusion
US5815413A (en) 1997-05-08 1998-09-29 Lockheed Martin Energy Research Corporation Integrated method for chaotic time series analysis
US6052619A (en) * 1997-08-07 2000-04-18 New York University Brain function scan system
US6479523B1 (en) 1997-08-26 2002-11-12 Emory University Pharmacologic drug combination in vagal-induced asystole
US6622036B1 (en) 2000-02-09 2003-09-16 Cns Response Method for classifying and treating physiologic brain imbalances using quantitative EEG
US6931274B2 (en) 1997-09-23 2005-08-16 Tru-Test Corporation Limited Processing EEG signals to predict brain damage
US5941906A (en) * 1997-10-15 1999-08-24 Medtronic, Inc. Implantable, modular tissue stimulator
US5938688A (en) 1997-10-22 1999-08-17 Cornell Research Foundation, Inc. Deep brain stimulation method
US6354299B1 (en) 1997-10-27 2002-03-12 Neuropace, Inc. Implantable device for patient communication
US6459936B2 (en) 1997-10-27 2002-10-01 Neuropace, Inc. Methods for responsively treating neurological disorders
US6597954B1 (en) 1997-10-27 2003-07-22 Neuropace, Inc. System and method for controlling epileptic seizures with spatially separated detection and stimulation electrodes
US6647296B2 (en) 1997-10-27 2003-11-11 Neuropace, Inc. Implantable apparatus for treating neurological disorders
US6016449A (en) 1997-10-27 2000-01-18 Neuropace, Inc. System for treatment of neurological disorders
US6230049B1 (en) 1999-08-13 2001-05-08 Neuro Pace, Inc. Integrated system for EEG monitoring and electrical stimulation with a multiplicity of electrodes
US6427086B1 (en) 1997-10-27 2002-07-30 Neuropace, Inc. Means and method for the intracranial placement of a neurostimulator
US5931791A (en) * 1997-11-05 1999-08-03 Instromedix, Inc. Medical patient vital signs-monitoring apparatus
US6042548A (en) 1997-11-14 2000-03-28 Hypervigilant Technologies Virtual neurological monitor and method
US6248126B1 (en) 1998-01-12 2001-06-19 The Johns Hopkins University Technique for using heat flow management to treat brain disorders
US5978710A (en) 1998-01-23 1999-11-02 Sulzer Intermedics Inc. Implantable cardiac stimulator with safe noise mode
US6208893B1 (en) * 1998-01-27 2001-03-27 Genetronics, Inc. Electroporation apparatus with connective electrode template
US6227203B1 (en) 1998-02-12 2001-05-08 Medtronic, Inc. Techniques for controlling abnormal involuntary movements by brain stimulation and drug infusion
US5971594A (en) 1998-03-24 1999-10-26 Innovative Medical Devices, Inc. Medication dispensing system
US6266556B1 (en) 1998-04-27 2001-07-24 Beth Israel Deaconess Medical Center, Inc. Method and apparatus for recording an electroencephalogram during transcranial magnetic stimulation
US6018682A (en) 1998-04-30 2000-01-25 Medtronic, Inc. Implantable seizure warning system
US6411854B1 (en) * 1998-04-30 2002-06-25 Advanced Bionics Corporation Implanted ceramic case with enhanced ceramic case strength
US6374140B1 (en) 1998-04-30 2002-04-16 Medtronic, Inc. Method and apparatus for treating seizure disorders by stimulating the olfactory senses
US6006124A (en) 1998-05-01 1999-12-21 Neuropace, Inc. Means and method for the placement of brain electrodes
US5938689A (en) 1998-05-01 1999-08-17 Neuropace, Inc. Electrode configuration for a brain neuropacemaker
US5928272A (en) 1998-05-02 1999-07-27 Cyberonics, Inc. Automatic activation of a neurostimulator device using a detection algorithm based on cardiac activity
US7242984B2 (en) 1998-08-05 2007-07-10 Neurovista Corporation Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease
US6366813B1 (en) 1998-08-05 2002-04-02 Dilorenzo Daniel J. Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease
US7209787B2 (en) 1998-08-05 2007-04-24 Bioneuronics Corporation Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease
US7403820B2 (en) 1998-08-05 2008-07-22 Neurovista Corporation Closed-loop feedback-driven neuromodulation
US9375573B2 (en) 1998-08-05 2016-06-28 Cyberonics, Inc. Systems and methods for monitoring a patient's neurological disease state
US7747325B2 (en) 1998-08-05 2010-06-29 Neurovista Corporation Systems and methods for monitoring a patient's neurological disease state
US7277758B2 (en) 1998-08-05 2007-10-02 Neurovista Corporation Methods and systems for predicting future symptomatology in a patient suffering from a neurological or psychiatric disorder
US7231254B2 (en) 1998-08-05 2007-06-12 Bioneuronics Corporation Closed-loop feedback-driven neuromodulation
US7324851B1 (en) 1998-08-05 2008-01-29 Neurovista Corporation Closed-loop feedback-driven neuromodulation
US7599736B2 (en) 2001-07-23 2009-10-06 Dilorenzo Biomedical, Llc Method and apparatus for neuromodulation and physiologic modulation for the treatment of metabolic and neuropsychiatric disease
US9113801B2 (en) 1998-08-05 2015-08-25 Cyberonics, Inc. Methods and systems for continuous EEG monitoring
US8762065B2 (en) 1998-08-05 2014-06-24 Cyberonics, Inc. Closed-loop feedback-driven neuromodulation
US6171239B1 (en) 1998-08-17 2001-01-09 Emory University Systems, methods, and devices for controlling external devices by signals derived directly from the nervous system
AU5900299A (en) 1998-08-24 2000-03-14 Emory University Method and apparatus for predicting the onset of seizures based on features derived from signals indicative of brain activity
DE19844296A1 (en) 1998-09-18 2000-03-23 Biotronik Mess & Therapieg Arrangement for patient monitoring
US6668191B1 (en) 1998-10-26 2003-12-23 Birinder R. Boveja Apparatus and method for electrical stimulation adjunct (add-on) therapy of atrial fibrillation, inappropriate sinus tachycardia, and refractory hypertension with an external stimulator
US7076307B2 (en) 2002-05-09 2006-07-11 Boveja Birinder R Method and system for modulating the vagus nerve (10th cranial nerve) with electrical pulses using implanted and external components, to provide therapy neurological and neuropsychiatric disorders
US6356788B2 (en) 1998-10-26 2002-03-12 Birinder Bob Boveja Apparatus and method for adjunct (add-on) therapy for depression, migraine, neuropsychiatric disorders, partial complex epilepsy, generalized epilepsy and involuntary movement disorders utilizing an external stimulator
US6205359B1 (en) 1998-10-26 2001-03-20 Birinder Bob Boveja Apparatus and method for adjunct (add-on) therapy of partial complex epilepsy, generalized epilepsy and involuntary movement disorders utilizing an external stimulator
US6366814B1 (en) 1998-10-26 2002-04-02 Birinder R. Boveja External stimulator for adjunct (add-on) treatment for neurological, neuropsychiatric, and urological disorders
US6513046B1 (en) * 1999-12-15 2003-01-28 Tangis Corporation Storing and recalling information to augment human memories
US6496724B1 (en) 1998-12-31 2002-12-17 Advanced Brain Monitoring, Inc. Method for the quantification of human alertness
US6280198B1 (en) * 1999-01-29 2001-08-28 Scientific Learning Corporation Remote computer implemented methods for cognitive testing
US6650779B2 (en) 1999-03-26 2003-11-18 Georgia Tech Research Corp. Method and apparatus for analyzing an image to detect and identify patterns
US6923784B2 (en) 1999-04-30 2005-08-02 Medtronic, Inc. Therapeutic treatment of disorders based on timing information
US6356784B1 (en) 1999-04-30 2002-03-12 Medtronic, Inc. Method of treating movement disorders by electrical stimulation and/or drug infusion of the pendunulopontine nucleus
US6341236B1 (en) 1999-04-30 2002-01-22 Ivan Osorio Vagal nerve stimulation techniques for treatment of epileptic seizures
US6109269A (en) 1999-04-30 2000-08-29 Medtronic, Inc. Method of treating addiction by brain infusion
US6176242B1 (en) 1999-04-30 2001-01-23 Medtronic Inc Method of treating manic depression by brain infusion
US6161045A (en) 1999-06-01 2000-12-12 Neuropace, Inc. Method for determining stimulation parameters for the treatment of epileptic seizures
US6312378B1 (en) 1999-06-03 2001-11-06 Cardiac Intelligence Corporation System and method for automated collection and analysis of patient information retrieved from an implantable medical device for remote patient care
US6343226B1 (en) 1999-06-25 2002-01-29 Neurokinetic Aps Multifunction electrode for neural tissue stimulation
DE19930263A1 (en) * 1999-06-25 2000-12-28 Biotronik Mess & Therapieg Method and device for data transmission between an electromedical implant and an external device
US6587719B1 (en) 1999-07-01 2003-07-01 Cyberonics, Inc. Treatment of obesity by bilateral vagus nerve stimulation
US6221011B1 (en) 1999-07-26 2001-04-24 Cardiac Intelligence Corporation System and method for determining a reference baseline of individual patient status for use in an automated collection and analysis patient care system
CA2314517A1 (en) 1999-07-26 2001-01-26 Gust H. Bardy System and method for determining a reference baseline of individual patient status for use in an automated collection and analysis patient care system
US6304775B1 (en) 1999-09-22 2001-10-16 Leonidas D. Iasemidis Seizure warning and prediction
US6560486B1 (en) 1999-10-12 2003-05-06 Ivan Osorio Bi-directional cerebral interface system
US6473644B1 (en) 1999-10-13 2002-10-29 Cyberonics, Inc. Method to enhance cardiac capillary growth in heart failure patients
US6882881B1 (en) 1999-10-19 2005-04-19 The Johns Hopkins University Techniques using heat flow management, stimulation, and signal analysis to treat medical disorders
US6386882B1 (en) 1999-11-10 2002-05-14 Medtronic, Inc. Remote delivery of software-based training for implantable medical device systems
US7300449B2 (en) 1999-12-09 2007-11-27 Mische Hans A Methods and devices for the treatment of neurological and physiological disorders
US6309406B1 (en) 1999-11-24 2001-10-30 Hamit-Darwin-Fresh, Inc. Apparatus and method for inducing epileptic seizures in test animals for anticonvulsant drug screening
US6358281B1 (en) * 1999-11-29 2002-03-19 Epic Biosonics Inc. Totally implantable cochlear prosthesis
US20020035338A1 (en) 1999-12-01 2002-03-21 Dear Stephen P. Epileptic seizure detection and prediction by self-similar methods
US6873872B2 (en) 1999-12-07 2005-03-29 George Mason University Adaptive electric field modulation of neural systems
WO2001041867A1 (en) 1999-12-07 2001-06-14 Krasnow Institute Adaptive electric field modulation of neural systems
WO2001048676A1 (en) 1999-12-24 2001-07-05 Medtronic, Inc. Central network to facilitate remote collaboration with medical instruments
US8002700B2 (en) 1999-12-30 2011-08-23 Medtronic, Inc. Communications system for an implantable medical device and a delivery device
US6471645B1 (en) 1999-12-30 2002-10-29 Medtronic, Inc. Communications system for an implantable device and a drug dispenser
US6510340B1 (en) 2000-01-10 2003-01-21 Jordan Neuroscience, Inc. Method and apparatus for electroencephalography
US6328699B1 (en) 2000-01-11 2001-12-11 Cedars-Sinai Medical Center Permanently implantable system and method for detecting, diagnosing and treating congestive heart failure
US6970742B2 (en) * 2000-01-11 2005-11-29 Savacor, Inc. Method for detecting, diagnosing, and treating cardiovascular disease
US20010027384A1 (en) 2000-03-01 2001-10-04 Schulze Arthur E. Wireless internet bio-telemetry monitoring system and method
US6973342B1 (en) 2000-03-02 2005-12-06 Advanced Neuromodulation Systems, Inc. Flexible bio-probe assembly
US6473639B1 (en) 2000-03-02 2002-10-29 Neuropace, Inc. Neurological event detection procedure using processed display channel based algorithms and devices incorporating these procedures
US6484132B1 (en) 2000-03-07 2002-11-19 Lockheed Martin Energy Research Corporation Condition assessment of nonlinear processes
US6768969B1 (en) 2000-04-03 2004-07-27 Flint Hills Scientific, L.L.C. Method, computer program, and system for automated real-time signal analysis for detection, quantification, and prediction of signal changes
AU2001249785A1 (en) 2000-04-03 2001-10-15 Flint Hills Scientific, L.L.C. Method, computer program, and system for automated real-time signal analysis fordetection, quantification, and prediction of signal changes
US6466822B1 (en) 2000-04-05 2002-10-15 Neuropace, Inc. Multimodal neurostimulator and process of using it
US7660621B2 (en) * 2000-04-07 2010-02-09 Medtronic, Inc. Medical device introducer
US6441747B1 (en) * 2000-04-18 2002-08-27 Motorola, Inc. Wireless system protocol for telemetry monitoring
US6353754B1 (en) 2000-04-24 2002-03-05 Neuropace, Inc. System for the creation of patient specific templates for epileptiform activity detection
US6442421B1 (en) 2000-04-27 2002-08-27 Centre National De La Recherche Scientifique Method for the medical monitoring in real time of a patient from the analysis of electroencephalograms to characterize and differentiate between physiological or pathological conditions, and a method for anticipating epileptic seizures
US6453198B1 (en) 2000-04-28 2002-09-17 Medtronic, Inc. Power management for an implantable medical device
AU5662001A (en) * 2000-05-08 2001-11-20 Brainsgate Ltd. Method and apparatus for stimulating the sphenopalatine ganglion to modify properties of the bbb and cerebral blood flow
US6306403B1 (en) 2000-06-14 2001-10-23 Allergan Sales, Inc. Method for treating parkinson's disease with a botulinum toxin
US6687538B1 (en) 2000-06-19 2004-02-03 Medtronic, Inc. Trial neuro stimulator with lead diagnostics
US6505077B1 (en) * 2000-06-19 2003-01-07 Medtronic, Inc. Implantable medical device with external recharging coil electrical connection
US6782292B2 (en) 2000-06-20 2004-08-24 Advanced Bionics Corporation System and method for treatment of mood and/or anxiety disorders by electrical brain stimulation and/or drug infusion
US6434419B1 (en) * 2000-06-26 2002-08-13 Sam Technology, Inc. Neurocognitive ability EEG measurement method and system
US7010351B2 (en) * 2000-07-13 2006-03-07 Northstar Neuroscience, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US7146217B2 (en) 2000-07-13 2006-12-05 Northstar Neuroscience, Inc. Methods and apparatus for effectuating a change in a neural-function of a patient
US6811562B1 (en) 2000-07-31 2004-11-02 Epicor, Inc. Procedures for photodynamic cardiac ablation therapy and devices for those procedures
US6402678B1 (en) 2000-07-31 2002-06-11 Neuralieve, Inc. Means and method for the treatment of migraine headaches
JP2004507293A (en) 2000-08-15 2004-03-11 ザ　リージェンツ　オブ　ザ　ユニバーシティ　オブ　カリフォルニア Method and apparatus for reducing contamination of electrical signals
WO2002014635A1 (en) * 2000-08-17 2002-02-21 Biometix Pty Ltd. A security container for medicines and system for filling prescriptions
US6591138B1 (en) 2000-08-31 2003-07-08 Neuropace, Inc. Low frequency neurostimulator for the treatment of neurological disorders
US6443891B1 (en) 2000-09-20 2002-09-03 Medtronic, Inc. Telemetry modulation protocol system for medical devices
US20020077675A1 (en) 2000-09-26 2002-06-20 Transneuronix, Inc. Minimally invasive surgery placement of stimulation leads in mediastinal structures
US6488617B1 (en) 2000-10-13 2002-12-03 Universal Hedonics Method and device for producing a desired brain state
WO2002038031A2 (en) 2000-10-30 2002-05-16 Neuropace, Inc. System and method for determining stimulation parameters for the treatment of epileptic seizures
US7089059B1 (en) 2000-11-03 2006-08-08 Pless Benjamin D Predicting susceptibility to neurological dysfunction based on measured neural electrophysiology
US6534693B2 (en) 2000-11-06 2003-03-18 Afmedica, Inc. Surgically implanted devices having reduced scar tissue formation
US6591137B1 (en) 2000-11-09 2003-07-08 Neuropace, Inc. Implantable neuromuscular stimulator for the treatment of gastrointestinal disorders
US6529774B1 (en) 2000-11-09 2003-03-04 Neuropace, Inc. Extradural leads, neurostimulator assemblies, and processes of using them for somatosensory and brain stimulation
US7158833B2 (en) 2000-11-28 2007-01-02 Neuropace, Inc. Ferrule for cranial implant
US6618623B1 (en) 2000-11-28 2003-09-09 Neuropace, Inc. Ferrule for cranial implant
ATE311811T1 (en) * 2000-12-21 2005-12-15 Insulet Corp REMOTE CONTROL MEDICAL DEVICE
US7177701B1 (en) * 2000-12-29 2007-02-13 Advanced Bionics Corporation System for permanent electrode placement utilizing microelectrode recording methods
US6609025B2 (en) 2001-01-02 2003-08-19 Cyberonics, Inc. Treatment of obesity by bilateral sub-diaphragmatic nerve stimulation
US6788975B1 (en) 2001-01-30 2004-09-07 Advanced Bionics Corporation Fully implantable miniature neurostimulator for stimulation as a therapy for epilepsy
US6571125B2 (en) 2001-02-12 2003-05-27 Medtronic, Inc. Drug delivery device
US20040176359A1 (en) * 2001-02-20 2004-09-09 University Of Kentucky Research Foundation Intranasal Benzodiazepine compositions
US6597953B2 (en) 2001-02-20 2003-07-22 Neuropace, Inc. Furcated sensing and stimulation lead
US7299096B2 (en) * 2001-03-08 2007-11-20 Northstar Neuroscience, Inc. System and method for treating Parkinson's Disease and other movement disorders
US6901292B2 (en) 2001-03-19 2005-05-31 Medtronic, Inc. Control of externally induced current in an implantable pulse generator
US6889086B2 (en) * 2001-04-06 2005-05-03 Cardiac Pacemakers, Inc. Passive telemetry system for implantable medical device
US7916013B2 (en) * 2005-03-21 2011-03-29 Greatbatch Ltd. RFID detection and identification system for implantable medical devices
US7369897B2 (en) 2001-04-19 2008-05-06 Neuro And Cardiac Technologies, Llc Method and system of remotely controlling electrical pulses provided to nerve tissue(s) by an implanted stimulator system for neuromodulation therapies
US6572528B2 (en) 2001-04-20 2003-06-03 Mclean Hospital Corporation Magnetic field stimulation techniques
US6684105B2 (en) 2001-08-31 2004-01-27 Biocontrol Medical, Ltd. Treatment of disorders by unidirectional nerve stimulation
US6901294B1 (en) * 2001-05-25 2005-05-31 Advanced Bionics Corporation Methods and systems for direct electrical current stimulation as a therapy for prostatic hypertrophy
US6901296B1 (en) * 2001-05-25 2005-05-31 Advanced Bionics Corporation Methods and systems for direct electrical current stimulation as a therapy for cancer and other neoplastic diseases
US6671555B2 (en) 2001-04-27 2003-12-30 Medtronic, Inc. Closed loop neuromodulation for suppression of epileptic activity
US6810285B2 (en) 2001-06-28 2004-10-26 Neuropace, Inc. Seizure sensing and detection using an implantable device
US6606521B2 (en) 2001-07-09 2003-08-12 Neuropace, Inc. Implantable medical lead
US6694159B2 (en) * 2001-07-16 2004-02-17 Art, Advanced Research Technologies Inc. Choice of wavelengths for multiwavelength optical imaging
WO2003009207A1 (en) 2001-07-20 2003-01-30 Medical Research Group Ambulatory medical apparatus and method using a robust communication protocol
US6622038B2 (en) 2001-07-28 2003-09-16 Cyberonics, Inc. Treatment of movement disorders by near-diaphragmatic nerve stimulation
US6622047B2 (en) 2001-07-28 2003-09-16 Cyberonics, Inc. Treatment of neuropsychiatric disorders by near-diaphragmatic nerve stimulation
US6600956B2 (en) 2001-08-21 2003-07-29 Cyberonics, Inc. Circumneural electrode assembly
US6622041B2 (en) 2001-08-21 2003-09-16 Cyberonics, Inc. Treatment of congestive heart failure and autonomic cardiovascular drive disorders
US6547746B1 (en) 2001-08-27 2003-04-15 Andrew A. Marino Method and apparatus for determining response thresholds
US6760626B1 (en) 2001-08-29 2004-07-06 Birinder R. Boveja Apparatus and method for treatment of neurological and neuropsychiatric disorders using programmerless implantable pulse generator system
US6832200B2 (en) * 2001-09-07 2004-12-14 Hewlett-Packard Development Company, L.P. Apparatus for closed-loop pharmaceutical delivery
US6662035B2 (en) 2001-09-13 2003-12-09 Neuropace, Inc. Implantable lead connector assembly for implantable devices and methods of using it
US7136695B2 (en) 2001-10-12 2006-11-14 Pless Benjamin D Patient-specific template development for neurological event detection
US20030083716A1 (en) 2001-10-23 2003-05-01 Nicolelis Miguel A.L. Intelligent brain pacemaker for real-time monitoring and controlling of epileptic seizures
US6591132B2 (en) 2001-11-30 2003-07-08 Stellate Systems Inc. Artifact detection in encephalogram data using an event model
WO2003063684A2 (en) 2002-01-25 2003-08-07 Intellipatch, Inc. Evaluation of a patient and prediction of chronic symptoms
US6721603B2 (en) 2002-01-25 2004-04-13 Cyberonics, Inc. Nerve stimulation as a treatment for pain
US20030144711A1 (en) 2002-01-29 2003-07-31 Neuropace, Inc. Systems and methods for interacting with an implantable medical device
US7110820B2 (en) 2002-02-05 2006-09-19 Tcheng Thomas K Responsive electrical stimulation for movement disorders
US7024249B2 (en) * 2002-02-21 2006-04-04 Alfred E. Mann Foundation For Scientific Research Pulsed magnetic control system for interlocking functions of battery powered living tissue stimulators
US20030176806A1 (en) 2002-02-26 2003-09-18 Pineda Jaime A. Method and system for an intelligent supervisory control system
DE10215115A1 (en) 2002-04-05 2003-10-16 Oliver Holzner Method and device for the prevention of epileptic seizures
US6990372B2 (en) * 2002-04-11 2006-01-24 Alfred E. Mann Foundation For Scientific Research Programmable signal analysis device for detecting neurological signals in an implantable device
US6735467B2 (en) 2002-04-15 2004-05-11 Persyst Development Corporation Method and system for detecting seizures using electroencephalograms
US7146222B2 (en) 2002-04-15 2006-12-05 Neurospace, Inc. Reinforced sensing and stimulation leads and use in detection systems
US20030195588A1 (en) 2002-04-16 2003-10-16 Neuropace, Inc. External ear canal interface for the treatment of neurological disorders
US6950706B2 (en) 2002-04-26 2005-09-27 Medtronic, Inc. Wave shaping for an implantable medical device
US6937891B2 (en) 2002-04-26 2005-08-30 Medtronic, Inc. Independent therapy programs in an implantable medical device
US7191012B2 (en) 2003-05-11 2007-03-13 Boveja Birinder R Method and system for providing pulsed electrical stimulation to a craniel nerve of a patient to provide therapy for neurological and neuropsychiatric disorders
US6921538B2 (en) 2002-05-10 2005-07-26 Allergan, Inc. Therapeutic treatments for neuropsychiatric disorders
US7177698B2 (en) * 2002-06-28 2007-02-13 Advanced Bionics Corporation Telemetry system for use with microstimulator
US7209861B2 (en) 2002-07-12 2007-04-24 Ut-Battelle Llc Methods for improved forewarning of critical events across multiple data channels
US7373198B2 (en) 2002-07-12 2008-05-13 Bionova Technologies Inc. Method and apparatus for the estimation of anesthetic depth using wavelet analysis of the electroencephalogram
US7139677B2 (en) 2002-07-12 2006-11-21 Ut-Battelle, Llc Methods for consistent forewarning of critical events across multiple data channels
US6934580B1 (en) 2002-07-20 2005-08-23 Flint Hills Scientific, L.L.C. Stimulation methodologies and apparatus for control of brain states
US7460903B2 (en) 2002-07-25 2008-12-02 Pineda Jaime A Method and system for a real time adaptive system for effecting changes in cognitive-emotive profiles
US7007191B2 (en) * 2002-08-23 2006-02-28 Lsi Logic Corporation Method and apparatus for identifying one or more devices having faults in a communication loop
US7263467B2 (en) 2002-09-30 2007-08-28 University Of Florida Research Foundation Inc. Multi-dimensional multi-parameter time series processing for seizure warning and prediction
JP2005537115A (en) 2002-08-27 2005-12-08 ユニバーシティ オブ フロリダ Optimization of multidimensional time series processing for seizure warning and seizure prediction
US7277748B2 (en) 2002-09-13 2007-10-02 Neuropace, Inc. Spatiotemporal pattern recognition for neurological event detection and prediction in an implantable device
US20060200038A1 (en) * 2002-09-13 2006-09-07 Robert Savit Noninvasive nonlinear systems and methods for predicting seizure
US7460904B2 (en) * 2002-10-09 2008-12-02 Wake Forest University Health Sciences Wireless systems and methods for the detection of neural events using onboard processing
EP1579608A4 (en) 2002-10-11 2012-09-05 Flint Hills Scient Llc Method, computer program, and system for intrinsic timescale decomposition, filtering, and automated analysis of signals of arbitrary origin or timescale
ATE489031T1 (en) 2002-10-11 2010-12-15 Flint Hills Scient Llc MULTIMODAL SYSTEM FOR DETECTING AND CONTROLLING CHANGES IN THE STATE OF THE BRAIN
AU2003287159A1 (en) 2002-10-15 2004-05-04 Medtronic Inc. Synchronization and calibration of clocks for a medical device and calibrated clock
EP1629341A4 (en) 2002-10-15 2008-10-15 Medtronic Inc Multi-modal operation of a medical device system
AU2003286451A1 (en) 2002-10-15 2004-05-04 Medtronic Inc. Signal quality monitoring and control for a medical device system
AU2003285889A1 (en) 2002-10-15 2004-05-04 Medtronic Inc. Control of treatment therapy during start-up and during operation of a medical device system
WO2004036372A2 (en) 2002-10-15 2004-04-29 Medtronic Inc. Scoring of sensed neurological signals for use with a medical device system
EP1583464B1 (en) 2002-10-15 2014-04-09 Medtronic, Inc. Clustering of recorded patient neurological activity to determine length of a neurological event
EP1558130A4 (en) 2002-10-15 2009-01-28 Medtronic Inc Screening techniques for management of a nervous system disorder
US20040138647A1 (en) 2002-10-15 2004-07-15 Medtronic, Inc. Cycle mode providing redundant back-up to ensure termination of treatment therapy in a medical device system
WO2004036370A2 (en) 2002-10-15 2004-04-29 Medtronic Inc. Channel-selective blanking for a medical device system
EP1558121A4 (en) 2002-10-15 2008-10-15 Medtronic Inc Signal quality monitoring and control for a medical device system
US8543214B2 (en) 2002-10-15 2013-09-24 Medtronic, Inc. Configuring and testing treatment therapy parameters for a medical device system
WO2004034997A2 (en) 2002-10-15 2004-04-29 Medtronic Inc. Medical device system with relaying module for treatment of nervous system disorders
FR2845883B1 (en) 2002-10-18 2005-08-05 Centre Nat Rech Scient METHOD AND DEVICE FOR REAL-TIME MEDICAL OR COGNITIVE FOLLOW-UP BY ANALYZING BRAIN ELECTROMAGNETIC ACTIVITY OF AN INDIVIDUAL, APPLYING THE METHOD FOR CHARACTERIZING AND DIFFERENTIATING PHYSIOLOGICAL OR PATHOLOGICAL CONDITIONS
US20050010261A1 (en) 2002-10-21 2005-01-13 The Cleveland Clinic Foundation Application of stimulus to white matter to induce a desired physiological response
WO2004037342A2 (en) 2002-10-21 2004-05-06 The Cleveland Clinic Foundation Electrical stimulation of the brain
US20050049649A1 (en) 2002-10-21 2005-03-03 The Cleveland Clinic Foundation Electrical stimulation of the brain
US7212851B2 (en) * 2002-10-24 2007-05-01 Brown University Research Foundation Microstructured arrays for cortex interaction and related methods of manufacture and use
WO2004043536A1 (en) 2002-11-12 2004-05-27 Neuropace, Inc. System for adaptive brain stimulation
US20040243146A1 (en) 2002-11-18 2004-12-02 Chesbrough Richard M Method and apparatus for supporting a medical device
TR200202651A2 (en) * 2002-12-12 2004-07-21 Met�N�Tulgar the vücutádışındanádirekátedaviásinyaliátransferliáábeyinápil
US7294101B2 (en) 2002-12-21 2007-11-13 Neuropace, Inc. Means and methods for treating headaches
US7269455B2 (en) 2003-02-26 2007-09-11 Pineda Jaime A Method and system for predicting and preventing seizures
US20040199212A1 (en) 2003-04-01 2004-10-07 Fischell David R. External patient alerting system for implantable devices
AU2004238259B2 (en) * 2003-05-06 2010-02-18 Covidien Lp System and method of assessment of the efficacy of treatment of neurological disorders using the electroencephalogram
US7117108B2 (en) * 2003-05-28 2006-10-03 Paul Ernest Rapp System and method for categorical analysis of time dependent dynamic processes
US7454251B2 (en) * 2003-05-29 2008-11-18 The Cleveland Clinic Foundation Excess lead retaining and management devices and methods of using same
US20050004622A1 (en) 2003-07-03 2005-01-06 Advanced Neuromodulation Systems System and method for implantable pulse generator with multiple treatment protocols
US20050033369A1 (en) 2003-08-08 2005-02-10 Badelt Steven W. Data Feedback loop for medical therapy adjustment
US7680537B2 (en) 2003-08-18 2010-03-16 Cardiac Pacemakers, Inc. Therapy triggered by prediction of disordered breathing
US7813809B2 (en) 2004-06-10 2010-10-12 Medtronic, Inc. Implantable pulse generator for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue
US20050059867A1 (en) * 2003-09-13 2005-03-17 Cheng Chung Yuan Method for monitoring temperature of patient
US7252090B2 (en) 2003-09-15 2007-08-07 Medtronic, Inc. Selection of neurostimulator parameter configurations using neural network
US7617002B2 (en) 2003-09-15 2009-11-10 Medtronic, Inc. Selection of neurostimulator parameter configurations using decision trees
US7502650B2 (en) 2003-09-22 2009-03-10 Cvrx, Inc. Baroreceptor activation for epilepsy control
US7129836B2 (en) 2003-09-23 2006-10-31 Ge Medical Systems Information Technologies, Inc. Wireless subject monitoring system
US20050070970A1 (en) 2003-09-29 2005-03-31 Knudson Mark B. Movement disorder stimulation with neural block
US8190248B2 (en) * 2003-10-16 2012-05-29 Louisiana Tech University Foundation, Inc. Medical devices for the detection, prevention and/or treatment of neurological disorders, and methods related thereto
US20050113744A1 (en) 2003-11-21 2005-05-26 Cyberkinetics, Inc. Agent delivery systems and related methods under control of biological electrical signals
US20050113885A1 (en) 2003-11-26 2005-05-26 Haubrich Gregory J. Patient notification of medical device telemetry session
US7813799B2 (en) 2003-12-08 2010-10-12 Cardiac Pacemakers, Inc. Adaptive safety pacing
US7174212B1 (en) * 2003-12-10 2007-02-06 Pacesetter, Inc. Implantable medical device having a casing providing high-speed telemetry
EP1734920A2 (en) * 2004-02-13 2006-12-27 Neuromolecular Inc. Combination of a nmda receptor antagonist and an mao-inhibitor or a gadph-inhibitor for the treatment of psychiatric conditions
US20050182420A1 (en) * 2004-02-13 2005-08-18 Schulte Gregory T. Low profile apparatus for securing a therapy delivery device within a burr hole
US20050187789A1 (en) 2004-02-25 2005-08-25 Cardiac Pacemakers, Inc. Advanced patient and medication therapy management system and method
US20050203584A1 (en) * 2004-03-10 2005-09-15 Medtronic, Inc. Telemetry antenna for an implantable medical device
US20050203366A1 (en) * 2004-03-12 2005-09-15 Donoghue John P. Neurological event monitoring and therapy systems and related methods
US7805196B2 (en) * 2004-03-16 2010-09-28 Medtronic, Inc. Collecting activity information to evaluate therapy
US8055348B2 (en) 2004-03-16 2011-11-08 Medtronic, Inc. Detecting sleep to evaluate therapy
US7881798B2 (en) * 2004-03-16 2011-02-01 Medtronic Inc. Controlling therapy based on sleep quality
US7387608B2 (en) 2004-04-06 2008-06-17 David A Dunlop Apparatus and method for the treatment of sleep related disorders
JP4705952B2 (en) 2004-04-07 2011-06-22 カーディアック ペースメイカーズ， インコーポレイテッド System and method for RF transceiver duty cycle in implantable medical devices
US7283856B2 (en) 2004-04-09 2007-10-16 Neuro Pace, Inc. Implantable lead system with seed electrodes
US7272435B2 (en) 2004-04-15 2007-09-18 Ge Medical Information Technologies, Inc. System and method for sudden cardiac death prediction
US20050231374A1 (en) 2004-04-15 2005-10-20 Diem Bjorn H Data management system
US7035076B1 (en) * 2005-08-15 2006-04-25 Greatbatch-Sierra, Inc. Feedthrough filter capacitor assembly with internally grounded hermetic insulator
US7532936B2 (en) 2004-04-20 2009-05-12 Advanced Neuromodulation Systems, Inc. Programmable switching device for implantable device
EP1740267A4 (en) 2004-04-28 2008-06-25 Transoma Medical Inc Implantable medical devices and related methods
US7463917B2 (en) 2004-04-28 2008-12-09 Medtronic, Inc. Electrodes for sustained delivery of energy
US20050245984A1 (en) 2004-04-30 2005-11-03 Medtronic, Inc. Implantable medical device with lubricious material
WO2005117693A1 (en) 2004-05-27 2005-12-15 Children's Medical Center Corporation Patient-specific seizure onset detection system
US7450991B2 (en) 2004-05-28 2008-11-11 Advanced Neuromodulation Systems, Inc. Systems and methods used to reserve a constant battery capacity
WO2006006159A1 (en) * 2004-07-09 2006-01-19 Aerotel Medical Systems (1998) Ltd. A wearable device, system and method for monitoring physiological and/or environmental parameters
WO2006019822A2 (en) * 2004-07-14 2006-02-23 Arizona Technology Enterprises Pacemaker for treating physiological system dysfunction
JP2008506464A (en) * 2004-07-15 2008-03-06 ノーススター ニューロサイエンス インコーポレイテッド System and method for enhancing or influencing neural stimulation efficiency and / or efficacy
US20060025828A1 (en) 2004-07-28 2006-02-02 Armstrong Randolph K Impedance measurement for an implantable device
US20060058627A1 (en) 2004-08-13 2006-03-16 Flaherty J C Biological interface systems with wireless connection and related methods
WO2006035392A1 (en) 2004-09-27 2006-04-06 Koninklijke Philips Electronics N. V. Biosensors for the analysis of samples
US8560041B2 (en) * 2004-10-04 2013-10-15 Braingate Co., Llc Biological interface system
EP1827217B1 (en) * 2004-11-02 2010-08-11 Medtronic, Inc. Techniques for data reporting in an implantable medical device
US20060122469A1 (en) * 2004-11-16 2006-06-08 Martel Normand M Remote medical monitoring system
US20060129056A1 (en) * 2004-12-10 2006-06-15 Washington University Electrocorticography telemitter
US8112153B2 (en) * 2004-12-17 2012-02-07 Medtronic, Inc. System and method for monitoring or treating nervous system disorders
US20060293578A1 (en) 2005-02-03 2006-12-28 Rennaker Robert L Ii Brian machine interface device
US7493167B2 (en) * 2005-03-22 2009-02-17 Greatbatch-Sierra, Inc. Magnetically shielded AIMD housing with window for magnetically actuated switch
US20060253096A1 (en) 2005-04-15 2006-11-09 Blakley Daniel R Intelligent medical cabinet
WO2006135791A2 (en) * 2005-06-09 2006-12-21 Medtronic, Inc. Peripheral nerve field stimulation and spinal cord stimulation
US7769472B2 (en) * 2005-07-29 2010-08-03 Medtronic, Inc. Electrical stimulation lead with conformable array of electrodes
US20070027367A1 (en) * 2005-08-01 2007-02-01 Microsoft Corporation Mobile, personal, and non-intrusive health monitoring and analysis system
US20070055320A1 (en) * 2005-09-07 2007-03-08 Northstar Neuroscience, Inc. Methods for treating temporal lobe epilepsy, associated neurological disorders, and other patient functions
US9042974B2 (en) * 2005-09-12 2015-05-26 New York University Apparatus and method for monitoring and treatment of brain disorders
US7729773B2 (en) * 2005-10-19 2010-06-01 Advanced Neuromodualation Systems, Inc. Neural stimulation and optical monitoring systems and methods
EP1965696A2 (en) 2005-12-20 2008-09-10 Koninklijke Philips Electronics N.V. Device for detecting and warning of a medical condition
US20070149952A1 (en) 2005-12-28 2007-06-28 Mike Bland Systems and methods for characterizing a patient's propensity for a neurological event and for communicating with a pharmacological agent dispenser
US8868172B2 (en) 2005-12-28 2014-10-21 Cyberonics, Inc. Methods and systems for recommending an appropriate action to a patient for managing epilepsy and other neurological disorders
US8725243B2 (en) 2005-12-28 2014-05-13 Cyberonics, Inc. Methods and systems for recommending an appropriate pharmacological treatment to a patient for managing epilepsy and other neurological disorders
US8078618B2 (en) * 2006-01-30 2011-12-13 Eastman Kodak Company Automatic multimode system for organizing and retrieving content data files
US20070287931A1 (en) 2006-02-14 2007-12-13 Dilorenzo Daniel J Methods and systems for administering an appropriate pharmacological treatment to a patient for managing epilepsy and other neurological disorders
US7787945B2 (en) * 2006-03-08 2010-08-31 Neuropace, Inc. Implantable seizure monitor
US8209018B2 (en) * 2006-03-10 2012-06-26 Medtronic, Inc. Probabilistic neurological disorder treatment
US8002701B2 (en) 2006-03-10 2011-08-23 Angel Medical Systems, Inc. Medical alarm and communication system and methods
US20070217121A1 (en) * 2006-03-14 2007-09-20 Greatbatch Ltd. Integrated Filter Feedthrough Assemblies Made From Low Temperature Co-Fired (LTCC) Tape
JP5649303B2 (en) * 2006-03-30 2015-01-07 エスアールアイ インターナショナルＳＲＩ Ｉｎｔｅｒｎａｔｉｏｎａｌ Method and apparatus for annotating media streams
US20080027515A1 (en) 2006-06-23 2008-01-31 Neuro Vista Corporation A Delaware Corporation Minimally Invasive Monitoring Systems
US7885706B2 (en) 2006-09-20 2011-02-08 New York University System and device for seizure detection
US20080091090A1 (en) * 2006-10-12 2008-04-17 Kenneth Shane Guillory Self-contained surface physiological monitor with adhesive attachment
US8380311B2 (en) * 2006-10-31 2013-02-19 Medtronic, Inc. Housing for implantable medical device
US9913593B2 (en) * 2006-12-27 2018-03-13 Cyberonics, Inc. Low power device with variable scheduling
US20080161712A1 (en) * 2006-12-27 2008-07-03 Kent Leyde Low Power Device With Contingent Scheduling
US8075499B2 (en) 2007-05-18 2011-12-13 Vaidhi Nathan Abnormal motion detector and monitor
US20080221876A1 (en) 2007-03-08 2008-09-11 Universitat Fur Musik Und Darstellende Kunst Method for processing audio data into a condensed version
US8036736B2 (en) 2007-03-21 2011-10-11 Neuro Vista Corporation Implantable systems and methods for identifying a contra-ictal condition in a subject
US7917218B2 (en) 2007-03-21 2011-03-29 Medtronic, Inc. Filtering capacitor feedthrough assembly
WO2009009724A1 (en) 2007-07-11 2009-01-15 Mayo Foundation For Medical Education And Research Seizure forecasting, microseizure precursor events, and related therapeutic methods and devices
JP2012033673A (en) 2010-07-30 2012-02-16 Nec Tokin Corp Magnetic element and manufacturing method of the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002058536A2 (en) * 2000-10-20 2002-08-01 The Trustees Of The University Of Pennsylvania Predicting and detecting seizure onsets
WO2002049500A2 (en) * 2000-12-12 2002-06-27 The Trustees Of The University Of Pennsylvania Forecasting and controlling neurological disturbances
US20050124863A1 (en) * 2001-06-28 2005-06-09 Cook Daniel R. Drug profiling apparatus and method

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
FRANASZCZUK, P.J. AND BERGEY, G.K: "An autoregressive method for the measurement of synchronization of interictal and ictal EEG signals", BIOLOGICAL CYBERNETICS, vol. 81, no. 1, 1999, pages 3 - 9, XP002488615 *
LE VAN QUYEN M ET AL: "Preictal state identification by synchronization changes in long-term intracranial EEG recordings", CLINICAL NEUROPHYSIOLOGY, ELSEVIER SCIENCE, IE, vol. 116, no. 3, 1 March 2005 (2005-03-01), pages 559 - 568, XP004766631, ISSN: 1388-2457 *
LEHNERTZ, K. AND ANDRZEJAK, R.G. AND ARNHOLD, J. AND KREUZ, T. AND MORMANN, F. AND RIEKE, C. AND WIDMAN, G. AND ELGER, C.E.},: "Nonlinear EEG Analysis in Epilepsy: Its Possible Use for Interictal Focus Localization, Seizure Anticipation, and Prevention", JOURNAL OF CLINICAL NEUROPHYSIOLOGY, vol. 18, no. 3, 2001, pages 209 - 222, XP002488616 *

Also Published As

Publication number Publication date
EP2126785A2 (en) 2009-12-02
WO2008092119A2 (en) 2008-07-31
US20080183096A1 (en) 2008-07-31
US9898656B2 (en) 2018-02-20

Similar Documents

Publication Publication Date Title
WO2008092119A3 (en) Systems and methods for identifying a contra-ictal condition in a subject
WO2012015808A3 (en) A system and method for reducing false alarms associated with vital-signs monitoring
WO2006063084A3 (en) Vital signs monitor using an optical ear-based module
WO2004030525A3 (en) Systems and methods for providing trend analysis in a sedation and analgesia system
WO2012025622A3 (en) Monitoring method and system for assessment or prediction of mood trends
WO2007130997A3 (en) Method and device for filtering, segmenting, compressing and classifying oscillatory signals
WO2010031070A3 (en) Patient monitor including multi-parameter graphical display
WO2008092133A3 (en) Methods and systems for measuring a subject's susceptibility to a seizure
WO2007070551A3 (en) Providing authentication of remotely collected external sensor measures
ATE460882T1 (en) REAL-TIME MONITORING OF THE STATE OF THE VEGETATED NERVOUS SYSTEM
WO2007089328A3 (en) System and method for monitoring health using exhaled breath
WO2006136174A3 (en) Methods and systems for assessing hearing ability
WO2007103377A3 (en) Systems and methods using a dynamic database to provide aesthetic improvement procedures
WO2007015200A3 (en) Apparatus for monitoring a person having an interest to an object, and method thereof
WO2006099120A3 (en) Mobile wireless customizable health and condition monitor
WO2007149856A3 (en) Automatic and ambulatory monitoring of congestive heart failure patients
MX2009007880A (en) Tools for aiding in the diagnosis of neurodegenerative diseases.
WO2007040963A3 (en) Internet-based system for monitoring blood test, vital sign, and exercise information from a patient
AU2003291239A1 (en) System and method for assessing the functional ability or medical condition of an actor
AU2003212608A1 (en) System and method for assessing and indicating the health of components
WO2008109603A3 (en) Vital sign monitor for cufflessly measuring blood pressure without using an external calibration
WO2007062029A3 (en) System and method of monitoring respiratory events
WO2012021179A3 (en) System and method to assess and report the health of landing gear related components
WO2007103474A3 (en) Drug adherence monitoring system
WO2006041789A3 (en) Apparatuses and methods for non-invasively monitoring blood parameters

Legal Events

Date Code Title Description
NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2008728338

Country of ref document: EP