WO2008115694A3 - Polymerization of multifunctional azides, and polymers therefrom - Google Patents

Polymerization of multifunctional azides, and polymers therefrom Download PDF

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Publication number
WO2008115694A3
WO2008115694A3 PCT/US2008/055905 US2008055905W WO2008115694A3 WO 2008115694 A3 WO2008115694 A3 WO 2008115694A3 US 2008055905 W US2008055905 W US 2008055905W WO 2008115694 A3 WO2008115694 A3 WO 2008115694A3
Authority
WO
WIPO (PCT)
Prior art keywords
multifunctional
polymers
polymerization
azides
polymers therefrom
Prior art date
Application number
PCT/US2008/055905
Other languages
French (fr)
Other versions
WO2008115694A2 (en
Inventor
Michael E. Benz
Metasebia T. Munie
Lian L. Luo
Original Assignee
Medtronic, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic, Inc. filed Critical Medtronic, Inc.
Publication of WO2008115694A2 publication Critical patent/WO2008115694A2/en
Publication of WO2008115694A3 publication Critical patent/WO2008115694A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • C07C247/02Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C247/04Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton being saturated

Abstract

Methods for preparing polymers from multifunctional azides and multifunctional azide-reactants are described in the present disclosure. Exemplary multifunctional azide-reactants include multifunctional alkynes and/or multifunctional α-phosphine esters. In certain embodiments, such polymers can be prepared in vivo. Such polymers can be useful in a wide variety of biomedical applications.
PCT/US2008/055905 2007-03-16 2008-03-05 Polymerization of multifunctional azides, and polymers therefrom WO2008115694A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91849707P 2007-03-16 2007-03-16
US60/918,497 2007-03-16

Publications (2)

Publication Number Publication Date
WO2008115694A2 WO2008115694A2 (en) 2008-09-25
WO2008115694A3 true WO2008115694A3 (en) 2010-06-03

Family

ID=39560915

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/055905 WO2008115694A2 (en) 2007-03-16 2008-03-05 Polymerization of multifunctional azides, and polymers therefrom

Country Status (1)

Country Link
WO (1) WO2008115694A2 (en)

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US8034396B2 (en) 2008-04-01 2011-10-11 Tyco Healthcare Group Lp Bioadhesive composition formed using click chemistry
AU2010215936B2 (en) 2009-02-21 2015-03-05 Covidien Lp Medical devices having activated surfaces
US8663689B2 (en) 2009-02-21 2014-03-04 Sofradim Production Functionalized adhesive medical gel
CA2753173C (en) 2009-02-21 2017-05-30 Sofradim Production Medical devices with an activated coating
EP2398584A2 (en) 2009-02-21 2011-12-28 Sofradim Production Apparatus and method of reaching polymers by exposure to uv radiation to produce injectable medical devices
US8968733B2 (en) * 2009-02-21 2015-03-03 Sofradim Production Functionalized surgical adhesives
US8877170B2 (en) 2009-02-21 2014-11-04 Sofradim Production Medical device with inflammatory response-reducing coating
EP2398943B1 (en) 2009-02-21 2013-04-17 Sofradim Production Crosslinked fibers and method of making same using uv radiation
US8512728B2 (en) 2009-02-21 2013-08-20 Sofradim Production Method of forming a medical device on biological tissue
US8535477B2 (en) 2009-02-21 2013-09-17 Sofradim Production Medical devices incorporating functional adhesives
AU2010215931A1 (en) 2009-02-21 2011-10-13 Covidien Lp Medical devices having activated surfaces
WO2010095047A2 (en) 2009-02-21 2010-08-26 Sofradim Production Apparatus and method of reacting polymers passing through metal ion chelated resin matrix to produce injectable medical devices
WO2010095052A2 (en) 2009-02-21 2010-08-26 Sofradim Production Compounds and medical devices activated with solvophobic linkers
CA2753179A1 (en) 2009-02-21 2010-08-26 Sofradim Production Crosslinked fibers and method of making same by extrusion
AU2010215192B2 (en) 2009-02-21 2015-04-30 Sofradim Production Amphiphilic compounds and self-assembling compositions made therefrom
WO2011117745A2 (en) 2010-03-25 2011-09-29 Sofradim Production Surgical fasteners and methods for sealing wounds
AU2011231245B2 (en) 2010-03-25 2015-03-26 Covidien Lp Medical devices incorporating functional adhesives
AU2011276443A1 (en) 2010-06-29 2013-01-31 Covidien Lp Microwave-powered reactor and method for in situ forming implants
CA2804251A1 (en) 2010-07-01 2012-01-05 Sofradim Production Medical device with predefined activated cellular integration
EP2598178B1 (en) 2010-07-27 2018-07-11 Sofradim Production Polymeric fibers having tissue reactive members
US9775928B2 (en) 2013-06-18 2017-10-03 Covidien Lp Adhesive barbed filament
AU2016353345B2 (en) 2015-11-12 2021-12-23 University Of Virginia Patent Foundation Compositions and methods for vas-occlusive contraception and reversal thereof
US10751124B2 (en) 2017-01-05 2020-08-25 Contraline, Inc. Methods for implanting and reversing stimuli-responsive implants
US11318040B2 (en) 2018-11-13 2022-05-03 Contraline, Inc. Systems and methods for delivering biomaterials

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070005140A1 (en) * 2005-06-29 2007-01-04 Kim Daniel H Fabrication and use of biocompatible materials for treating and repairing herniated spinal discs

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070005140A1 (en) * 2005-06-29 2007-01-04 Kim Daniel H Fabrication and use of biocompatible materials for treating and repairing herniated spinal discs

Also Published As

Publication number Publication date
WO2008115694A2 (en) 2008-09-25

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