WO2008148557A3 - Sample holder device for ionization chambers for mass spectometry - Google Patents

Sample holder device for ionization chambers for mass spectometry Download PDF

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Publication number
WO2008148557A3
WO2008148557A3 PCT/EP2008/004499 EP2008004499W WO2008148557A3 WO 2008148557 A3 WO2008148557 A3 WO 2008148557A3 EP 2008004499 W EP2008004499 W EP 2008004499W WO 2008148557 A3 WO2008148557 A3 WO 2008148557A3
Authority
WO
WIPO (PCT)
Prior art keywords
ionization
sample holder
holder device
apci
esi
Prior art date
Application number
PCT/EP2008/004499
Other languages
French (fr)
Other versions
WO2008148557A2 (en
Inventor
Gaetano Corso
Dott.Ssa Oceania D'apolito
Dott. Giuseppe Paglia
Original Assignee
Universita' Degli Studi Di Foggia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universita' Degli Studi Di Foggia filed Critical Universita' Degli Studi Di Foggia
Publication of WO2008148557A2 publication Critical patent/WO2008148557A2/en
Publication of WO2008148557A3 publication Critical patent/WO2008148557A3/en

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/14—Ion sources; Ion guns using particle bombardment, e.g. ionisation chambers
    • H01J49/142—Ion sources; Ion guns using particle bombardment, e.g. ionisation chambers using a solid target which is not previously vapourised
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409—Sample holders or containers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0468—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample

Abstract

A sample holder device for ionization chambers is disclosed. The sample holder device of the present invention allows to perform DESI measurements (desorption electrospray ionization mass spectrometry) in ionization chambers equipped with facilities for other mass spectrometry ionization techniques such as ESI (electrospray ionization mass spectrometry) and APCI (atmospheric pressure chemical ionization). By simply and easily inserting the sample holder device according to the present invention in a ionization chamber equipped for instance with ESI or APCI facilities, it is possible to work with a further ionization technique (DESI) in the same ionization chamber without costly and time-consuming modifications of the chamber. It is thus possible to profit of all the advantages of the DESI technique and, at the same time, to compare the results obtained with those obtained with other ionization techniques such as ESI or APCI.
PCT/EP2008/004499 2007-06-05 2008-06-05 Sample holder device for ionization chambers for mass spectometry WO2008148557A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM2007A000312 2007-06-05
IT000312A ITRM20070312A1 (en) 2007-06-05 2007-06-05 SAMPLE HOLDER DEVICE FOR ROOMS FOR IONIZATION OF MASS SPECTROMETERS

Publications (2)

Publication Number Publication Date
WO2008148557A2 WO2008148557A2 (en) 2008-12-11
WO2008148557A3 true WO2008148557A3 (en) 2009-11-12

Family

ID=39967135

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/004499 WO2008148557A2 (en) 2007-06-05 2008-06-05 Sample holder device for ionization chambers for mass spectometry

Country Status (2)

Country Link
IT (1) ITRM20070312A1 (en)
WO (1) WO2008148557A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201420933D0 (en) * 2014-11-25 2015-01-07 Univ Huddersfield Analytical apparatus and method of use of the same
WO2016142681A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Spectrometric analysis of microbes
US11289320B2 (en) 2015-03-06 2022-03-29 Micromass Uk Limited Tissue analysis by mass spectrometry or ion mobility spectrometry
EP4257967A3 (en) 2015-03-06 2024-03-27 Micromass UK Limited Collision surface for improved ionisation
CN108700590B (en) 2015-03-06 2021-03-02 英国质谱公司 Cell population analysis
WO2016142679A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Chemically guided ambient ionisation mass spectrometry
CN107530065A (en) 2015-03-06 2018-01-02 英国质谱公司 In vivo Microendoscopic tissue identification instrument
DE202016008460U1 (en) 2015-03-06 2018-01-22 Micromass Uk Limited Cell population analysis
KR102017409B1 (en) 2015-03-06 2019-10-21 마이크로매스 유케이 리미티드 Improved Ionization Methods for Gaseous Samples
EP3265817B1 (en) 2015-03-06 2020-08-12 Micromass UK Limited Rapid evaporative ionisation mass spectrometry ("reims") and desorption electrospray ionisation mass spectrometry ("desi-ms") analysis of swabs and biopsy samples
WO2016142692A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Spectrometric analysis
GB201517195D0 (en) 2015-09-29 2015-11-11 Micromass Ltd Capacitively coupled reims technique and optically transparent counter electrode
US11454611B2 (en) 2016-04-14 2022-09-27 Micromass Uk Limited Spectrometric analysis of plants

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2355108A (en) * 1999-08-07 2001-04-11 Bruker Daltonik Gmbh Mass spectrometer with interchangeable ion sources and ion guides
US20050056776A1 (en) * 2000-06-09 2005-03-17 Willoughby Ross C. Laser desorption ion source

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2355108A (en) * 1999-08-07 2001-04-11 Bruker Daltonik Gmbh Mass spectrometer with interchangeable ion sources and ion guides
US20050056776A1 (en) * 2000-06-09 2005-03-17 Willoughby Ross C. Laser desorption ion source

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"Thorlabs Catalog 2004", 2004, pages: 132, XP007909597 *
"Thorlabs, MA45-2 drawing", 3 March 2003 (2003-03-03), XP007909469, Retrieved from the Internet <URL:http://www.thorlabs.de/Thorcat/0200/0248-E0W.pdf> [retrieved on 20090811] *
WATERS: "Waters. Micromass Quattro Micro API Tandem Quadrupole System", INTERNET CITATION, 1 August 2002 (2002-08-01), pages 1 - 20, XP007909006, Retrieved from the Internet <URL:http://las.perkinelmer.de/Content/featured/MSMS/BRO_WatersQuattroMicro.pdf> [retrieved on 20090626] *

Also Published As

Publication number Publication date
ITRM20070312A1 (en) 2008-12-06
WO2008148557A2 (en) 2008-12-11

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