WO2009082535A3 - Method and device for microreactor pressure control - Google Patents

Method and device for microreactor pressure control Download PDF

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Publication number
WO2009082535A3
WO2009082535A3 PCT/US2008/080200 US2008080200W WO2009082535A3 WO 2009082535 A3 WO2009082535 A3 WO 2009082535A3 US 2008080200 W US2008080200 W US 2008080200W WO 2009082535 A3 WO2009082535 A3 WO 2009082535A3
Authority
WO
WIPO (PCT)
Prior art keywords
fluid
microfluidic
microfluidic reactor
pressure control
permeable membrane
Prior art date
Application number
PCT/US2008/080200
Other languages
French (fr)
Other versions
WO2009082535A2 (en
Inventor
R. Michael Van Dam
Kan Liu
Kwang-Fu Clifton Shen
Hsian-Rong Tseng
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Publication of WO2009082535A2 publication Critical patent/WO2009082535A2/en
Publication of WO2009082535A3 publication Critical patent/WO2009082535A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00905—Separation
    • B01J2219/00907—Separation using membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/0095—Control aspects
    • B01J2219/00952—Sensing operations
    • B01J2219/00968—Type of sensors
    • B01J2219/0097—Optical sensors

Abstract

A microfluidic device has a device body, wherein the device body defines a microfluidic reactor and a pressure control system therein, the pressure control system being arranged proximate the microfluidic reactor. The microfluidic device also has a fluid-permeable membrane arranged between the microfluidic reactor and the pressure control system, the fluid-permeable membrane having a surface area and thickness such that a fluid can pass from a high pressure side to a low pressure side of said fluid-permeable membrane during operation of the microfluidic device to at least one of change a pressure in the microfluidic reactor in a preselected manner, to maintain a substantially constant pressure in the microfluidic reactor, to change a composition of fluids in the microfluidic reactor, or maintain a composition of fluids in the microfluidic reactor. A method on performing chemical reactions includes introducing a plurality of chemical substances into a microfluidic reactor, wherein the microfluidic reactor has a fluid-permeable membrane between at least a portion of the microfluidic reactor and a microfluidic pressure control system; and at least one of pressurizing with a fluid or evacuating a region of the pressure control system proximate the fluid-permeable membrane to cause fluid to pass through the fluid-permeable membrane in a predetermined manner in order to cause a predetermined effect on a chemical reaction in the microfluidic reactor.
PCT/US2008/080200 2007-10-16 2008-10-16 Method and device for microreactor pressure control WO2009082535A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96084407P 2007-10-16 2007-10-16
US60/960,844 2007-10-16

Publications (2)

Publication Number Publication Date
WO2009082535A2 WO2009082535A2 (en) 2009-07-02
WO2009082535A3 true WO2009082535A3 (en) 2010-03-18

Family

ID=40801736

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/080200 WO2009082535A2 (en) 2007-10-16 2008-10-16 Method and device for microreactor pressure control

Country Status (1)

Country Link
WO (1) WO2009082535A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2200931B1 (en) 2007-09-19 2017-06-07 The Charles Stark Draper Laboratory, Inc. Microfluidic structures with circular cross-section
US9067189B2 (en) 2012-03-30 2015-06-30 General Electric Company Microfluidic device and a related method thereof
WO2014190258A1 (en) 2013-05-23 2014-11-27 The Regents Of The University Of California Proximal degas driven microfluidic actuation
WO2016044532A1 (en) 2014-09-17 2016-03-24 The Regents Of The University Of California Vacuum battery system for portable microfluidic pumping

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6375901B1 (en) * 1998-06-29 2002-04-23 Agilent Technologies, Inc. Chemico-mechanical microvalve and devices comprising the same
US20050037471A1 (en) * 2003-08-11 2005-02-17 California Institute Of Technology Microfluidic rotary flow reactor matrix
US20050266582A1 (en) * 2002-12-16 2005-12-01 Modlin Douglas N Microfluidic system with integrated permeable membrane
US20070178133A1 (en) * 2005-11-09 2007-08-02 Liquidia Technologies, Inc. Medical device, materials, and methods

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6375901B1 (en) * 1998-06-29 2002-04-23 Agilent Technologies, Inc. Chemico-mechanical microvalve and devices comprising the same
US20050266582A1 (en) * 2002-12-16 2005-12-01 Modlin Douglas N Microfluidic system with integrated permeable membrane
US20050037471A1 (en) * 2003-08-11 2005-02-17 California Institute Of Technology Microfluidic rotary flow reactor matrix
US20070178133A1 (en) * 2005-11-09 2007-08-02 Liquidia Technologies, Inc. Medical device, materials, and methods

Also Published As

Publication number Publication date
WO2009082535A2 (en) 2009-07-02

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