WO2012162569A3 - Magnetoencephalography source imaging - Google Patents

Magnetoencephalography source imaging Download PDF

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Publication number
WO2012162569A3
WO2012162569A3 PCT/US2012/039478 US2012039478W WO2012162569A3 WO 2012162569 A3 WO2012162569 A3 WO 2012162569A3 US 2012039478 W US2012039478 W US 2012039478W WO 2012162569 A3 WO2012162569 A3 WO 2012162569A3
Authority
WO
WIPO (PCT)
Prior art keywords
signal data
brain
locations
magnetoencephalography
source imaging
Prior art date
Application number
PCT/US2012/039478
Other languages
French (fr)
Other versions
WO2012162569A2 (en
Inventor
Ming-xiong HUANG
Roland R. Lee
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Priority to CN201280036640.7A priority Critical patent/CN103717129A/en
Priority to EP12789805.4A priority patent/EP2713867A4/en
Priority to US14/118,886 priority patent/US20140378815A1/en
Publication of WO2012162569A2 publication Critical patent/WO2012162569A2/en
Publication of WO2012162569A3 publication Critical patent/WO2012162569A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/242—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents
    • A61B5/245—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents specially adapted for magnetoencephalographic [MEG] signals
    • A61B5/246—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents specially adapted for magnetoencephalographic [MEG] signals using evoked responses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/242—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents
    • A61B5/245—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents specially adapted for magnetoencephalographic [MEG] signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7253—Details of waveform analysis characterised by using transforms
    • A61B5/7257—Details of waveform analysis characterised by using transforms using Fourier transforms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4806—Functional imaging of brain activation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4808—Multimodal MR, e.g. MR combined with positron emission tomography [PET], MR combined with ultrasound or MR combined with computed tomography [CT]
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5602—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by filtering or weighting based on different relaxation times within the sample, e.g. T1 weighting using an inversion pulse
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56341—Diffusion imaging

Abstract

Techniques, devices and systems are disclosed for magnetoencephalography (MEG) source imaging. In one aspect, a method includes selecting signal data associated with one or more frequency bands from a spectrum of the signal data in the frequency domain, in which the signal data represents magnetic signals emitted by a brain of a subject and detected by a plurality of sensors outside the brain, defining locations of sources within the brain that generate the magnetic signals, in which the number of locations of the sources is selected to be greater than the number of sensors, and generating a source value of signal power based on the selected signal data corresponding to a respective location of the locations at the one or more frequencies.
PCT/US2012/039478 2011-05-24 2012-05-24 Magnetoencephalography source imaging WO2012162569A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN201280036640.7A CN103717129A (en) 2011-05-24 2012-05-24 Magnetoencephalography source imaging
EP12789805.4A EP2713867A4 (en) 2011-05-24 2012-05-24 Magnetoencephalography source imaging
US14/118,886 US20140378815A1 (en) 2011-05-24 2012-05-24 Magnetoencephalography source imaging

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161489667P 2011-05-24 2011-05-24
US61/489,667 2011-05-24

Publications (2)

Publication Number Publication Date
WO2012162569A2 WO2012162569A2 (en) 2012-11-29
WO2012162569A3 true WO2012162569A3 (en) 2013-01-24

Family

ID=47218106

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2012/039478 WO2012162569A2 (en) 2011-05-24 2012-05-24 Magnetoencephalography source imaging

Country Status (4)

Country Link
US (1) US20140378815A1 (en)
EP (1) EP2713867A4 (en)
CN (1) CN103717129A (en)
WO (1) WO2012162569A2 (en)

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US8593141B1 (en) 2009-11-24 2013-11-26 Hypres, Inc. Magnetic resonance system and method employing a digital squid
US8970217B1 (en) 2010-04-14 2015-03-03 Hypres, Inc. System and method for noise reduction in magnetic resonance imaging
US10433742B2 (en) 2013-08-05 2019-10-08 The Regents Of The University Of California Magnetoencephalography source imaging for neurological functionality characterizations
US10702208B2 (en) * 2015-03-31 2020-07-07 Cerenion Oy Apparatus and method for electroencephalographic examination
JP2018519029A (en) * 2015-05-27 2018-07-19 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． Motion detection with multi-element radio frequency antenna
US10751017B2 (en) 2015-06-17 2020-08-25 Siemens Heatlhcare GmbH Modular automated scoring system for TBI assessment
US10441172B2 (en) * 2015-08-05 2019-10-15 Seiko Epson Corporation Brain image reconstruction apparatus
CN105212895B (en) * 2015-08-24 2019-01-15 中国科学院苏州生物医学工程技术研究所 Dynamic brain source localization method
CN105816165B (en) * 2016-05-04 2019-12-13 把脉(上海)信息科技有限公司 real-time dynamic heart rate monitoring device and monitoring method
CN109863512B (en) * 2016-09-01 2023-10-20 通用医疗公司 System and method for automatic transformation by manifold approximation
US10678240B2 (en) * 2016-09-08 2020-06-09 Mentor Graphics Corporation Sensor modification based on an annotated environmental model
CN106923790B (en) * 2017-01-17 2019-12-24 上海理工大学 High-precision quick positioning system and method in magnetoencephalogram detection
WO2018162307A1 (en) * 2017-03-10 2018-09-13 Koninklijke Philips N.V. Seizure characterization with magnetic resonance imaging (mri) fused with an electroencephalography (eeg) model
WO2018200723A1 (en) 2017-04-25 2018-11-01 Washington University Resorbable implant for stimulating tissue, systems including such implant, and methods of using
EP3621518A4 (en) * 2017-05-12 2021-01-06 The Korea Research Institute of Standards and Science (KRISS) Multi-sensor magneto-monitoring-imaging system
CN107550493B (en) * 2017-07-14 2020-09-08 北京大学 Time-varying constraint electroencephalogram or magnetoencephalogram tracing method based on functional magnetic resonance imaging
EP3684463A4 (en) 2017-09-19 2021-06-23 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement
US11717686B2 (en) 2017-12-04 2023-08-08 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to facilitate learning and performance
US11318277B2 (en) 2017-12-31 2022-05-03 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to enhance emotional response
JP6961274B2 (en) * 2018-02-22 2021-11-05 バヤール イメージング リミテッド Detection and measurement of correlated movement using MIMO radar
CN108514413B (en) * 2018-04-04 2023-09-22 漫迪医疗仪器（上海）有限公司 Dewar biological magnetic detection system, design method/system thereof and readable storage medium
US11364361B2 (en) 2018-04-20 2022-06-21 Neuroenhancement Lab, LLC System and method for inducing sleep by transplanting mental states
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US11786694B2 (en) 2019-05-24 2023-10-17 NeuroLight, Inc. Device, method, and app for facilitating sleep
CN112168167B (en) * 2020-09-25 2022-05-03 北京大学 Magnetoencephalogram single auditory evoked signal detection method and electronic device
CN112220482B (en) * 2020-09-25 2021-07-30 北京大学 Method for detecting and eliminating magnetoencephalogram eye movement artifact based on neural network and electronic device
CN112674773B (en) * 2020-12-22 2021-12-24 北京航空航天大学 Magnetoencephalogram source positioning method and device based on Tucker decomposition and ripple time window
CN113143293B (en) * 2021-04-12 2023-04-07 天津大学 Continuous speech envelope nerve entrainment extraction method based on electroencephalogram source imaging
CN113031782B (en) * 2021-04-22 2023-01-24 深圳大学 Motor imagery feedback method, system and storage medium
CN113616181B (en) * 2021-09-17 2023-07-21 北京航空航天大学 Multi-mode optical and magnetic nanoparticle imaging fusion brain detection system
CN114065825B (en) * 2022-01-17 2022-04-19 北京航空航天大学杭州创新研究院 Brain magnetic MEG source positioning method based on structural similarity
CN117100277A (en) * 2022-07-25 2023-11-24 北京大学 Multi-mode synchronous brain imaging method based on magnetoencephalography and near infrared brain imaging

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Also Published As

Publication number Publication date
CN103717129A (en) 2014-04-09
EP2713867A2 (en) 2014-04-09
US20140378815A1 (en) 2014-12-25
WO2012162569A2 (en) 2012-11-29
EP2713867A4 (en) 2015-01-21

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