Disclosed is an esophageal bulking device for implantation below the mucosa in the vicinity of the lower esophageal sphincter. Preferably, the bulking device comprises an expandable hydrogel implant. Also disclosed are methods of treating gastroesophageal reflux disease, by implanting an expandable bulking...http://www.google.de/patents/US6725866?utm_source=gb-gplus-sharePatent US6725866 - Method of treating gastroesophageal reflux disease