Amplification and/or expression of nucleic acids is carried out in a medium immobilized by using an organic and/or inorganic solid matrix penetrating the medium and having a porous, fibrous, reticulated, coiled, capillary, lamellar or folded texture and which includes the components of a cell-free enzyme...http://www.google.de/patents/US5616478?utm_source=gb-gplus-sharePatent US5616478 - Method for amplification of nucleic acids in solid media