A fiber optic based probe has been designed to sample the fluorescence or phosphorescence signal from animal or human tissues, such that the light intensity is not multiply scattered. This type of measurement allows a linear detection of the concentration of the luminescent compound non-invasively from...http://www.google.de/patents/US6377842?utm_source=gb-gplus-sharePatent US6377842 - Method for quantitative measurement of fluorescent and phosphorescent drugs within tissue utilizing a fiber optic probe