Methods and devices for enhanced ultrasound detection based upon changing temperature and ultrasound reflectivity of a temperature-dependent contrast agent bound to an ultrasound target are disclosed. The methods and devices can be used for enhanced imaging alone or in conjunction with drug delivery,...http://www.google.de/patents/US20020102216?utm_source=gb-gplus-sharePatent US20020102216 - Enhanced ultrasound detection with temperature-dependent contrast agents