A means for cleaving a nucleic acid cleavage structure in a site-specific manner is disclosed. A cleaving enzyme having 5' nuclease activity without interfering nucleic acid synthetic ability is employed as the basis of a novel method of detection of specific nucleic acid sequences. ...http://www.google.de/patents/US5719028?utm_source=gb-gplus-sharePatent US5719028 - Cleavase fragment length polymorphism