A labeled primer for use in detection of nucleic acid is described, which primer is labeled at the two ends of the oligonucleotide strand with a reporter dye molecule and a quencher molecule, and in which labeled primer, at least one base at the 3' end is deliberately not complementary to the nucleic...http://www.google.de/patents/US6248526?utm_source=gb-gplus-sharePatent US6248526 - Labeled primer for use in and detection of target nucleic acids