Compositions and methods for modulating tumor proliferation in an individual are provided. The methods employ nucleolin-binding agents, such as aptamers. The aptamers of the present invention can be used to modulate the proliferation of malignant, dysplastic, hyperproliferative, and/or metastatic cells...http://www.google.de/patents/US8114850?utm_source=gb-gplus-sharePatent US8114850 - Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin
