Methods and devices to detect analyte in body fluid are provided. Embodiments include receiving one or more analyte sensor data, receiving a reference measurement value associated with an analyte level, determining a sensitivity parameter based on the received one or more analyte sensor data and the...http://www.google.de/patents/US8103456?utm_source=gb-gplus-sharePatent US8103456 - Method and device for early signal attenuation detection using blood glucose measurements