An apparatus and method for performing successive chemical or biochemical operations in an automated or semi-automated format are disclosed. The apparatus includes (i) a substrate having two or more wells, where each well is separated from adjacent well(s) by an energy barrier, (ii), a magnetic bead...http://www.google.de/patents/US7329392?utm_source=gb-gplus-sharePatent US7329392 - Device and method for handling reaction components