A method and apparatus is disclosed for the instant intraoperative detection and biopsy of metastatic cancer using fluorescence spectroscopy. A photosensitizing agent selectively retained by cancerous tissue is administered prior to surgery. A fiberoptic probe integrated with a biopsy device illuminates...http://www.google.de/patents/US5318023?utm_source=gb-gplus-sharePatent US5318023 - Apparatus and method of use for a photosensitizer enhanced fluorescence based biopsy needle