A method for detecting mutations, such as a single base change or an addition or deletion of about one to four base pairs, is based on the use of an immobilized DNA mismatch-binding protein, such as MutS, which binds to a nucleic acid hybrid having a single base mismatch or unpaired base or bases, thereby...http://www.google.de/patents/US6114115?utm_source=gb-gplus-sharePatent US6114115 - Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, and allele identification
