A method of synthesizing isolated, soluble peptides having constrained secondary structure in solution is described herein. The peptides are encoded by expressible oligonucleotides having a desirable bias of random codon sequences. ...http://www.google.de/patents/US5770434?utm_source=gb-gplus-sharePatent US5770434 - Soluble peptides having constrained, secondary conformation in solution and method of making same 
