A novel process for producing novel and/or improved heterofunctional binding fusion proteins termed Totally Synthetic Affinity Reagents (TSARS) is disclosed. TSARs are concatenated heterofunctional polypeptides or proteins comprising at least two functional regions: a binding domain with affinity for...http://www.google.de/patents/US5935823?utm_source=gb-gplus-sharePatent US5935823 - Totally synthetic affinity reagents