Novel methods for producing, and compositions of, humanized immunoglobulins having one or more complementarity determining regions (CDR's) and possible additional amino acids from a donor immunoglobulin and a framework region from an accepting human immunoglobulin are provided. Each...http://www.google.de/patents/US5693761?utm_source=gb-gplus-sharePatent US5693761 - Polynucleotides encoding improved humanized immunoglobulins
