A synthetic nuclease resistant antisense oligodeoxynucleotide (AS-ODN) capable of selectively modulating human acetylcholinesterase (AChE) production and a composition comprising at least one AS-ODN as an active ingredient. A nuclease resistant antisense targeted against the splice junction in the AChE...http://www.google.de/patents/US6121046?utm_source=gb-gplus-sharePatent US6121046 - Synthetic antisense oligodeoxynucleotides targeted to human ache