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United States Patent [19] [in Patent Number: 4,757,815

Strandberg et al. [45] Date of Patent: Jul. 19, 1988

[54] HEART PACEMAKER

[75] Inventors: Hans Strandberg, Sundbyberg;

Sven-Erik Hedberg, Kungsangen;
Martin Obel, Danderyd, all of
Sweden

[73] Assignee: Siemens Aktiengesellschaft, Berlin and Munich, Fed. Rep. of Germany

[21] Appl. No.: 942,719

[22] Filed: Dec. 17,1986

[30] Foreign Application Priority Data

Dec. 20, 1985 [DE] Fed. Rep. of Germany 3545359

[51] Int. Cl.« A61N 1/36

[52] U.S. CI 128/419 PG; 128/716;

128/671

[58] Field of Search 128/419 PG, 716, 671

[56] References Cited

U.S. PATENT DOCUMENTS

3,593,718 7/1971 Krasner 128/419

4,303,075 12/1981 Heilman et al 128/419 PG

4,365,636 12/1982 Barker 128/716

4,428,378 1/1984 Anderson et al 128/419 PG

4,596,251 6/1986 Plicchi et al 128/419 PG

FOREIGN PATENT DOCUMENTS 0089014 9/1983 European Pat. Off. 419 PG/

OTHER PUBLICATIONS

"Valsalva-Induced Variations in the Intracardiac Signal", Rosenqvist et al, PACE, vol. 8, Nov.-Dec. 1985, pp. 856-861.

"Variations of the Intraatrial Potential in Patients with a DDD Pacemaker," Langenfeld et al, Cardiac Pacing & Electrophysiology, Jun. 7-11, 1987, pp. 185-189. "Relationship Between Changes in R Wave Voltage & Cardiac Volumes. A Vectorcardiographs Study During Hemodialysis," Vitolo et al, J. Electrocardiology vol. 20(2), 1987, pp. 138-146.

Primary Examiner—William E. Kamm

Assistant Examiner—Timothy Keegan

Attorney, Agent, or Firm—Hill, Van Santen, Steadman &

Simpson

[57] ABSTRACT

A heart pacemaker has a pulse generator and circuitry for measuring a respiration signal of the user and a control unit for controlling the pulse generator by changing the pulse repetition rate dependent on the respiration signal. A heart action detector is provided for acquiring heart action signals and the respiration signal measuring circuitry includes detectors for measuring the amplitude fluctuations in the heart action signal and supplying those fluctuations to the control unit.

5 Claims, 1 Drawing Sheet

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4,757,815

1 2

pies of the present invention, this envelope corresponds HEART PACEMAKER to the respiration signal.

Two successive QRS complexes 4 and 5 are shown BACKGROUND OF THE INVENTION enlarged in FIG. 2 having different amplitudes. As

1. Field of the Invention 5 shown in FIG. 2, a measurement is undertaken for each The present invention relates to heart pacemakers, complex from the most positive point to the most nega

and in particular to heart pacemakers which vary the tive Point of the R wave, with the respective distances

output pulse rate based on respiration activity of the 6 311(1 7 between the peak values being the measure of

user. the respiration signal used in the present invention.

2. Description of the Prior Art 10 A schematic circuit diagram for a heart pacemaker Heart pacemakers are known which employ a respi- for operating based on the measurement principles deration signal obtained from the user of the pacemaker to scribed above is shown in FIG. 3. The pacemaker is vary the repetition rate of the pulses generated by the encapsulated in a housing 8 and comprises a pulse genpacemaker. Such pacemakers are described, for exam- erator 9 for generating heart pacing pulses which are pie, in U.S. Pat. No. 3,593,718 and in European patent 15 conducted to a heart 10 via an electrode line 11 having application No. 00 89 014. These known heart pacemak- an electrode tip 12 introduced in the heart 10. The paceers use an impedance pneumograph for acquiring a maker further includes an amplifier 13 for the incoming respiration signal. Such an impedance pneumograph heart action signals acquired by the electrode line 11. requires additional electrodes and energy for impe- The amplifier 13 is followed by a peak sensing means 14 dance measurement. 20 for QRS complexes including a first sample/hold ele

SUMMARY OF THE INVENTION ment 15a for positive peaks and a second sample/hold

element 15b for negative peaks.

It is an object of the present invention to provide a The acquired peak values are supplied through a heart pacemaker which varies the output pulse repeti- multiplexer 16 and an analog-to-digital converter 17 to tion rate in dependence upon a respiration signal from 23 a difference fonner 18. The difference former 18 forms the pacemaker user in a simple manner with low energy a signal corresponding to the differences between the consumption. acquired positive and negative peaks for each QRS

In accordance with the principles of the present in- ,ex ^ sj ^ of the difference former 18

vention, the above object is achieved m a pacemaker ig Ued tQ ... ^ w a k&tion si ^ for havmg a pulse generator, a respiration signal measuring *i ^ ^

taker. The control unit 19 controls the means, and control means for controlling the pulse , r . „ . , ... „ . ,

. , . , .... ° . c pulse generator 9 via a control line 20 so that the pulse

generator by modifymg the pulse repetition rate thereof tl. , ■ >• ,

dependent on the ration signal The pacemaker has "Pf'T rate ,of the pacmg Pulsfs 18 ...

a heart action detector for acquiring a heart action sig- smfted from a !ower Pacm/ ^te toward higher pacing

nal, and the respiration signal measuring means includes 35 rates with an mcreasmg frequency of the respiration

means for determining amplitude fluctuations in the ^ ■* the 0UtPut °f the difference former 18. The

heart action signal and supplying a signal corresponding ?aculS frequency is thus appropriately adapted to the

to those fluctuations to the control unit as the respira- ^creasing requirements of the pacemaker user m a sim

tion signal. Ple manner.

The respiration signal in the pacemaker disclosed 40 Although modifications and changes may be sugherein can thus be directly acquired from fluctuations of gested by those skilled in the art it is the mtention of the the heart action signal. An additional current for mak- inventors to embody within the patent warranted ing an impedance measurement is thus not required and hereon all changes and modifications as reasonably and no extra electrode is needed. The pacemaker is thus properly come within the scope of their contribution to technically simpler to construct and consumes less en- 45 the art. ergy to operate. We claim as our invention:

1. A heart pacemaker comprising: DESCRIPTION OF THE DRAWINGS pulse generator means for generating heart pacing

FIG. 1 is a schematic illustration of heart action sig- pulses; nals and their amplitude fluctuations from which a res- 50 means for acquiring a heart action signal from said piration signal can be derived. heart having amplitude fluctuations therein which

FIG. 2 is an enlarged portions of successive heart vary according to respiratory activity of the pace

action signals of the type shown in FIG. 1 and illustrates maker user;

the measuring principle employed by the pacemaker respiration signal measuring means for measuring said disclosed herein. 55 amplitude fluctuations and generating a respiration

FIG. 3 is a schematic block circuit diagram of a heart signal therefrom; and

pacemaker constructed in accordance with the princi- control means connected to said pulse generator pies of the present invention. means and to said respiration signal measuring

nuc^DTimmi /->=• Tuc ... means for changing the rate of said heart pacing

DESCRIPTION OF THEPREFERRED ^ signals generated by said pulse generator means in EMBODIMENTS response to said respiration signal.

A series of heart action signals 1 is shown in FIG. 1 2. A heart pacemaker as claimed in claim 1, wherein which are acquired by a heart pacemaker in a conven- said respiration signal measuring means comprises a first tional manner, such as by means of a QRS detector. The peak value sensor for sensing positive fluctuations and a amplitudes 2 (R waves) thereof are subject to fluctua- 65 second peak value sensor for sensing negative fluctuations caused by the respiration cycle of the user of the tions in said heart action signal, a difference former heart pacemaker. The envelope for all such fluctuations connected to the outputs of said first and second peak is referenced 3 in FIG. 1. In accordance with the princi- value sensors, said difference former measuring the

[blocks in formation]

distance between positive and negative peaks in said heart action signal, and said difference former being connected to said control unit for supplying a signal corresponding to said difference to said control unit as said respiration signal.

3. A heart pacemaker comprising: a pulse generator for generating pacing pulses for pacing a heart; a heart action signal detector for acquiring successive heart action signals which fluctuate positively and negatively corresponding to respiratory activity of the pacemaker user; means connecting said pulse generator and said heart

action detector to said heart; a first sample/hold circuit having an input connected to said heart action detector for measuring positive peaks of said heart action signals; a second sample/hold circuit having an input connected to an output of said heart action detector for measuring negative peaks of said heart action signals;

a difference former having an input to which the outputs of said first and second sample/hold cir

10

15

20

cuits are supplied, said difference former generating a respiration signal as an output which corresponds to the difference between the positive and negative peaks measured by said first and second sample/hold circuits; and a control unit having an input connected to said difference former for receiving said respiration signal therefrom and an output connected to said pulse generator for controlling said pulse generator in dependence upon said respiration signal.

4. A heart pacemaker as claimed in claim 3, further comprising a multiplexer controlled by said control unit interconnected between said outputs of said first and second sample/hold circuits and the input of said difference former for alternatingly supplying the outputs of said first and sample/hold circuits to said input of said difference former.

5. A heart pacemaker as claimed in claim 4, further comprising an analog-to-digial converter interconnected between said multiplexer and said difference former.

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