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(12) United States Patent
Marossero et al.
(io) Patent No.: (45) Date of Patent:
US 7,333,850 B2 Feb. 19, 2008
(54) MATERNAL-FETAL MONITORING SYSTEM
(75) Inventors: Dorothee Marossero, Gainesville, FL (US); Tammy Y. Euliano, Gainesville, FL (US); Neil Russell Euliano, II, Gainesville, FL (US); Jose C. Principe,
Gainesville, FL (US)
(73) Assignees: University of Florida Research
Foundation, Inc., Gainesville, FL (US);
Convergent Engineering, Inc.,
Gainesville, FL (US)
( * ) Notice: Subject to any disclaimer, the term of this patent is extended or adjusted under 35 U.S.C. 154(b) by 305 days.
(21) Appl. No.: 10/857,107
(22) Filed: May 28, 2004
(65) Prior Publication Data
US 2005/0267376 Al Dec. 1, 2005
(51) Int. CI.
A61B 5/0444 (2006.01)
(52) U.S. CI 600/511
(58) Field of Classification Search 600/511,
600/376, 304 See application file for complete search history.
A maternal-fetal monitoring system for use during all stages of pregnancy, including antepartum and intrapartum stages. The maternal-fetal monitoring system of the subject invention comprises (1) a set of sensors; (2) an amplifying/ filtering means; (3) a computing means; and (4) a graphical user interface. Accurate clinical data, which can be extracted and provided to the user in real-time using the system of the invention, include without limitation, maternal electrocardiogram (ECG) signals, maternal uterine activity signals (EHG), maternal heart rate, fetal ECG signals, and fetal heart rate. In a preferred embodiment, the maternal-fetal monitoring system of the invention includes an intelligence means, such as a neural network system, to analyze and interpret clinical data for use in clinical diagnosis antepartum, intrapartum and postpartum, as well as delivery strategy
22 Claims, 23 Drawing Sheets
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