US1180665A - Closure or stopper for serum-containers, &c. - Google Patents

Closure or stopper for serum-containers, &c. Download PDF

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Publication number
US1180665A
US1180665A US6392615A US6392615A US1180665A US 1180665 A US1180665 A US 1180665A US 6392615 A US6392615 A US 6392615A US 6392615 A US6392615 A US 6392615A US 1180665 A US1180665 A US 1180665A
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United States
Prior art keywords
stopper
cannula
lumen
serum
closure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US6392615A
Inventor
Patrick J Mcelroy
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RANDALL-FAICHNEY COMPANY Inc
RANDALL FAICHNEY Co Inc
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RANDALL FAICHNEY Co Inc
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Application filed by RANDALL FAICHNEY Co Inc filed Critical RANDALL FAICHNEY Co Inc
Priority to US6392615A priority Critical patent/US1180665A/en
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Publication of US1180665A publication Critical patent/US1180665A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/002Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S215/00Bottles and jars
    • Y10S215/03Medical

Definitions

  • This invention relates to a container'tor 1o storing and injecting serum, the container being provided with a stopper of compressible resilient material, such as rubber or cork, formed as a radially compressible plug and closing its outlet opening, and adapted to receive a-cannula through which the serum is ejected by means provided for that purpose.
  • a stopper of compressible resilient material such as rubber or cork
  • the stopper has heretofore been made imperforate, and is punctured by the cannula, the latter being provided With a sharply pointed inner end adapted to puncture the stopper.
  • a cannula is necessarily a slender or attenuated tube so that it is liable to be broken by the-force required to drive it through an imperforate stopper formed as a plug andradially' compressed .by the outlet wall in which it. is.
  • MclELROY or cartnarnen, nassacmi'sn'r'rs, assrenron or earn-e 1: an COMPY, we, or nos'ron', raassacn'usnrrs.
  • Fig. 2 represents a view sirni- -lar to Fig. l, the' cannula being present
  • Fig. 3 represents an enlarged section on line 33 of Fig. 1
  • Fig. 4 represents an enlarged
  • the stopper has been pro- "rendered liquid-tight b is embodied in an article: of manufacture, to wit,*a stopperltormed as a radiall compressible plug having a longi-lf body of the 'stopper 'permitting the easy. insertion of a cannula-having a blunt inner &c.
  • stopper is radially compressed by insertion "in the container outlet, the stopper constituting a liquidtight closure when the cannula is absent.
  • Fig. 8 represents a sectional view showing the stopper represented by Fig. 7 in-' sorted in a container outlet;
  • Fig, 9 represents a section on line 9-9 of mg. 7;
  • Fig. 10 represents a section on line. 10-10 of Fig.7.
  • '12 represents the body and 13 the outlet of a serum container of an suitable form, thecontainer being provi ed with means (not shown) for e ecting the serum throu h a cannula inserted in the stopper hereina 'er described.
  • l-t represents a stopper or closure made of compressible elastic material such as rubber or cork and formed as a plu to be inserted in the outlet 13 and radially compressed by the wall of said outletform in.
  • the stopper 14a longitudinal lumen 15 which is surrounded by the body ot the stopperand is'normally closed and the resilience of be' curvedfa's indicated by Figs.
  • the lumen preferablylhas parallel sides normallypressed closely together. :1
  • Fig. 5 showing a lumen which is cruciform in cross section, so that it has more than two abutting sides.
  • Fig. 6 shows a lumen having two abutting sides, said sides being flat instead of curved.
  • the lumen may be formed in the otherwise completed body of the stopper by a suitvulcanization and being subsequently removed.
  • Figs. 7 and 8 I show a lumen having a normally closed portion 15 characterize 'as above stated, extending from the inner end of the stopper partly to its outer end, and an enlarged normally open portion'l9 extending from the normally closed portion to the outer-end-of the stopper, and adapted to receive the cannula without being a preciably' distended thereby, so that the frictional resistance to the insertion of the cannula is considerably reduced,
  • the stopper is self-sealing because its lumen is automatically closed or sealed as above described.
  • a resilient self-sealing apertured closure or stopper formed as a radially compressible plug provided with a longitudinal lumen surrounded by the body of the stopper and including an inner portion extending from the inner end of the stopper partly to its outer end, and adapted to be closed by radial compression of the surrounding portion of the stopper, and an enlarged normally open outer portion extending to the outer end of the stop-- per, and formed to receive a cannula Without being distended thereby, the inner portion being distensible by the cannula.

Description

P. J. McELROY.
CLOSURE 0R STOPPER FOR SERUM CONTAINERS, 8w.
APPLICATlON FILED NOV. 29. 1915.
Patented Apr. 25, 1916.
(I FATRIU JLMQEL U w i A insects.
I To all whom) it may concern:
-]Be it known that I, PATRICK J..MEr.nor,
a citizen oi the United States, residing at Cambridge, in the county of l /lliddlesex and State of Massachusetts,- have invented new and useful Improvements in Closures or Stoppers tor Serum-Containers, &c.,-' of which. the following is a specification;
This invention relates to a container'tor 1o storing and injecting serum, the container being provided with a stopper of compressible resilient material, such as rubber or cork, formed as a radially compressible plug and closing its outlet opening, and adapted to receive a-cannula through which the serum is ejected by means provided for that purpose.
In some cases the stopper has heretofore been made imperforate, and is punctured by the cannula, the latter being provided With a sharply pointed inner end adapted to puncture the stopper. A cannula is necessarily a slender or attenuated tube so that it is liable to be broken by the-force required to drive it through an imperforate stopper formed as a plug andradially' compressed .by the outlet wall in which it. is.
inserted. Moreover'it is not an easy matter to so .drive'the cannula that itwill be centrally located and parallel with the axis at the stopper. There is also liability of clogging the inner endi'of the lumen of the. cannula by -material separated from the body of thesto'pper by the cutting action of the cannula.
vided with .a passage or lumen for the re- 4'0 permits liqu d to. pass through. it when the cannula is not present, the cannula being-v provided with means whereby the escape of" liquid is prevented when the cannula .is' partly withdrawn from fits'foperative 'position.
My invention end; and normall closed and rendered MclELROY, or cartnarnen, nassacmi'sn'r'rs, assrenron or earn-e 1: an COMPY, we, or nos'ron', raassacn'usnrrs.
= present on s'rorrnn m. snnurr-conrarm :1 r .1
particularly when the a part of'this speci sents a longitudinal section of a stopper fiembodying my invention inserted in the goutletend of a serum container, the cannula :being absent; Fig. 2 represents a view sirni- -lar to Fig. l, the' cannula being present; Fig. 3 represents an enlarged section on line 33 of Fig. 1; Fig. 4 represents an enlarged In other cases the stopper has been pro- "rendered liquid-tight b is embodied in an article: of manufacture, to wit,*a stopperltormed as a radiall compressible plug having a longi-lf body of the 'stopper 'permitting the easy. insertion of a cannula-having a blunt inner &c.
Specification of Le ers Patent. l pmtgmhgd App, 25, 11%1, Application filed November ae, raw. Serial No. 633%. i
stopper is radially compressed by insertion "in the container outlet, the stopper constituting a liquidtight closure when the cannula is absent.
Of the accoinpanging drawings forming cation, Figure 1 represection on line H of Fig. 2; Figs. 5 and '6 represent transverse sections of a stopper showing diderent forms of lumina; Fig. 7
represents a longitudinal section of a sto]pt e per having a lumen extending from,
inner end of the stopper partly to the outer end; Fig. 8 represents a sectional view showing the stopper represented by Fig. 7 in-' sorted in a container outlet; Fig, 9 represents a section on line 9-9 of mg. 7; Fig. 10 represents a section on line. 10-10 of Fig.7.
The same reference characters indicate the same or similar parts in all the views.
fill
in. the drawings, '12 represents the body and 13 the outlet of a serum container of an suitable form, thecontainer being provi ed with means (not shown) for e ecting the serum throu h a cannula inserted in the stopper hereina 'er described.
l-t represents a stopper or closure made of compressible elastic material such as rubber or cork and formed as a plu to be inserted in the outlet 13 and radially compressed by the wall of said outletform in. the stopper 14a longitudinal lumen 15 which is surrounded by the body ot the stopperand is'normally closed and the resilience of be' curvedfa's indicated by Figs.
The lumen preferablylhas parallel sides normallypressed closely together. :1 The said sides-may h 4 I 3, 4 and 10. They may however beother lience of, id body,
said body and is more tightly closed-by the radial. compression of; said body caused by itsinsertionin the outlet '13, the o eration of formingsaid lumen being one oft e steps otthe operation ct manufacturing the stopwisejtetmcd, as indicated by .llliffi; and 6., g I
Fig. 5 showing a lumen which is cruciform in cross section, so that it has more than two abutting sides. Fig. 6 shows a lumen having two abutting sides, said sides being flat instead of curved.
The lumen may be formed in the otherwise completed body of the stopper by a suitvulcanization and being subsequently removed.
It will now be seen that when a cannula 16 having a blunt inner end 17 and a lateral liquid bore 18 communicating with the lumen of the cannula is inserted in the stopper lumen 15, it is enabled by'the latter to pass readily through the stopper, the sides of the stopper lumen being pressed closely against the periphery of the cannula and forming a liquid-tight joint therewith. When the cannula is removed the sides 'of the stopper lumen close together so that no liquid can escape therethrough.
In Figs. 7 and 8 I show a lumen having a normally closed portion 15 characterize 'as above stated, extending from the inner end of the stopper partly to its outer end, and an enlarged normally open portion'l9 extending from the normally closed portion to the outer-end-of the stopper, and adapted to receive the cannula without being a preciably' distended thereby, so that the frictional resistance to the insertion of the cannula is considerably reduced,
The stopper is self-sealing because its lumen is automatically closed or sealed as above described.
. closed throughout its length by the elasticity of the said body, whereby the lumen is selfsealing and liquid tight, said lumen being distensible by a blunt ended cannula inserted in It. e
2. As an article of manufacture, a resilient self-sealing apertured closure or stopper formed as a radially compressible plug provided with a longitudinal lumen surrounded by the body of the stopper and including an inner portion extending from the inner end of the stopper partly to its outer end, and adapted to be closed by radial compression of the surrounding portion of the stopper, and an enlarged normally open outer portion extending to the outer end of the stop-- per, and formed to receive a cannula Without being distended thereby, the inner portion being distensible by the cannula.
In testimony whereof I have affixed my signature. I 1
PATRICK J. MOELROY.
US6392615A 1915-11-29 1915-11-29 Closure or stopper for serum-containers, &c. Expired - Lifetime US1180665A (en)

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Cited By (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2903990A (en) * 1956-08-29 1959-09-15 Reinforced Plastics Corp Marine fender
US2906423A (en) * 1956-07-18 1959-09-29 American Cyanamid Co Closure puncturable by polyethylene needle
US3009217A (en) * 1958-02-28 1961-11-21 Chase Bottle & Supply Corp Clinical thermometer retainer
US3659587A (en) * 1970-06-30 1972-05-02 Affiliated Hospital Prod Valved connector arrangement
US3739779A (en) * 1970-04-28 1973-06-19 Medical Electroscience & Pharm Hypodermic syringe and needle construction
US3811441A (en) * 1972-02-10 1974-05-21 Survival Technology Cartridge syringe
US3853127A (en) * 1973-04-03 1974-12-10 R Spademan Elastic sealing member
US3977403A (en) * 1975-02-24 1976-08-31 The Kendall Company Catheter adapter
FR2400198A1 (en) * 1977-08-11 1979-03-09 Braun Melsungen Ag DEVICE FOR DETERMINING THE RATE OF SEDIMENTATION OF RED BLOOD CELLS
US4244478A (en) * 1979-06-27 1981-01-13 Mpl, Inc. Closure assembly for unit dose vial
WO1983001912A1 (en) * 1981-11-30 1983-06-09 Suovaniemi, Osmo Safety device for sealing a test tube
US4545497A (en) * 1984-11-16 1985-10-08 Millipore Corporation Container cap with frangible septum
US4761078A (en) * 1984-05-14 1988-08-02 Farris Richard J Deformation calorimeter
US5080654A (en) * 1989-09-18 1992-01-14 Applied Medical Technology, Inc. Fluid injection device for intravenous delivery system
US5215537A (en) * 1990-09-13 1993-06-01 Lynn Lawrence A Septum for a blunt cannula
US5300034A (en) * 1992-07-29 1994-04-05 Minnesota Mining And Manufacturing Company Iv injection site for the reception of a blunt cannula
US5322516A (en) * 1993-05-20 1994-06-21 Cobe Laboratories, Inc. Safety needle system and method for using the same
US5328041A (en) * 1993-06-30 1994-07-12 Abbott Laboratories Two piece stopper for blunt fluid connector
EP0354947B1 (en) * 1988-01-25 1994-07-20 BAXTER INTERNATIONAL INC. (a Delaware corporation) Pre-slit injection site and tapered cannula
US5351383A (en) * 1992-07-29 1994-10-04 Minnesota Mining And Manufacturing Company Method of making an injection or sampling site
US5354275A (en) * 1993-09-13 1994-10-11 Minnesota Mining And Manufacturing Company Injection or sampling site
US5376077A (en) * 1992-12-04 1994-12-27 Interventional Technologies, Inc. Introducer sheath with seal protector
US5443791A (en) * 1990-04-06 1995-08-22 Perkin Elmer - Applied Biosystems Division Automated molecular biology laboratory
US5549577A (en) * 1993-12-29 1996-08-27 Ivac Corporation Needleless connector
US5622183A (en) * 1993-11-09 1997-04-22 Hazard; James T. Urine specimen and other body fluids collection device
US5658260A (en) * 1988-01-25 1997-08-19 Baxter International Inc. Bayonet lock cannula for pre-slit y-site
US5776125A (en) * 1991-07-30 1998-07-07 Baxter International Inc. Needleless vial access device
US5795784A (en) * 1996-09-19 1998-08-18 Abbott Laboratories Method of performing a process for determining an item of interest in a sample
US5856194A (en) * 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
US5928935A (en) * 1995-09-26 1999-07-27 Reuss, Jr.; William Alexander Biological specimen containment and incubation device
US5957898A (en) * 1997-05-20 1999-09-28 Baxter International Inc. Needleless connector
US5983770A (en) * 1994-08-03 1999-11-16 Abbott Laboratories Reseal with a partial perforation and method and apparatus for creating a partial perforation in a reseal
US6050935A (en) * 1997-05-09 2000-04-18 Biofertec Container assembly for intravaginal fertilization and culture and embryo transfer and method of intravaginal fertilization and culture employing such a container
US6193697B1 (en) 1987-03-17 2001-02-27 Baxter International Inc. Pre-slit injection site and tapered cannula
US6213996B1 (en) 1988-01-25 2001-04-10 Baxter International Inc. Pre-slit injection site and tapered cannula
US6261282B1 (en) 1997-05-20 2001-07-17 Baxter International Inc. Needleless connector
WO2002036182A2 (en) * 2000-11-03 2002-05-10 Chromatography Research Supplies, Inc. Septum with chamfer and linear pre-piercing
US20020085959A1 (en) * 1991-03-04 2002-07-04 Glen Carey Cuvette for an automated analyzer
US6416499B2 (en) 1997-07-30 2002-07-09 Cook Incorporated Medical fluid flow control valve
US20020091359A1 (en) * 2000-12-12 2002-07-11 Luca Caleffi Site for access to the inside of a channel, and corresponding cannula
US20030194349A1 (en) * 1991-03-04 2003-10-16 Glen Carey Fluid handling apparatus for an automated analyzer
US6663599B2 (en) 1992-05-06 2003-12-16 Cook Incorporated Hemostasis cannula
US20040199126A1 (en) * 2001-12-07 2004-10-07 Harding Weston F Needleless luer access connector
US20040217081A1 (en) * 2003-04-17 2004-11-04 Grainer Bio-One Gmbh Container system and closure device comprising a sealing device and cap
US20050192537A1 (en) * 1992-05-06 2005-09-01 Osborne Thomas A. Hemostasis cannula
US20060013729A1 (en) * 1991-02-14 2006-01-19 Glen Carey Fluid handling apparatus for an automated analyzer
US20060142705A1 (en) * 2003-04-24 2006-06-29 Halili Edgardo C Implantable medication delivery device having needle receiving slot
US20080289975A1 (en) * 2007-05-23 2008-11-27 Imperial Toy, Llc Spill Resistant Container and Toy
US7635357B2 (en) 1994-06-20 2009-12-22 Mayer Bruno Franz P Needleless injection site
US20130174937A1 (en) * 2011-07-26 2013-07-11 Hainan Weikang Pharmaceutical (Qianshan) Co.,Ltd Puncture Free Bottle Cork and the Application Thereof
US8864725B2 (en) 2009-03-17 2014-10-21 Baxter Corporation Englewood Hazardous drug handling system, apparatus and method

Cited By (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2906423A (en) * 1956-07-18 1959-09-29 American Cyanamid Co Closure puncturable by polyethylene needle
US2903990A (en) * 1956-08-29 1959-09-15 Reinforced Plastics Corp Marine fender
US3009217A (en) * 1958-02-28 1961-11-21 Chase Bottle & Supply Corp Clinical thermometer retainer
US3739779A (en) * 1970-04-28 1973-06-19 Medical Electroscience & Pharm Hypodermic syringe and needle construction
US3659587A (en) * 1970-06-30 1972-05-02 Affiliated Hospital Prod Valved connector arrangement
US3811441A (en) * 1972-02-10 1974-05-21 Survival Technology Cartridge syringe
US3853127A (en) * 1973-04-03 1974-12-10 R Spademan Elastic sealing member
US3977403A (en) * 1975-02-24 1976-08-31 The Kendall Company Catheter adapter
FR2400198A1 (en) * 1977-08-11 1979-03-09 Braun Melsungen Ag DEVICE FOR DETERMINING THE RATE OF SEDIMENTATION OF RED BLOOD CELLS
US4187719A (en) * 1977-08-11 1980-02-12 B. Braun Melsungen Aktiengesellschaft Apparatus to determine the sedimentation rate of red blood cells
US4244478A (en) * 1979-06-27 1981-01-13 Mpl, Inc. Closure assembly for unit dose vial
WO1983001912A1 (en) * 1981-11-30 1983-06-09 Suovaniemi, Osmo Safety device for sealing a test tube
US4761078A (en) * 1984-05-14 1988-08-02 Farris Richard J Deformation calorimeter
US4545497A (en) * 1984-11-16 1985-10-08 Millipore Corporation Container cap with frangible septum
US6193697B1 (en) 1987-03-17 2001-02-27 Baxter International Inc. Pre-slit injection site and tapered cannula
US5797897A (en) * 1988-01-25 1998-08-25 Baxter International Inc. Pre-slit injection site and tapered cannula
US5658260A (en) * 1988-01-25 1997-08-19 Baxter International Inc. Bayonet lock cannula for pre-slit y-site
US6605076B1 (en) 1988-01-25 2003-08-12 Baxter International Inc. Pre-slit injection site and tapered cannula
US6447498B1 (en) 1988-01-25 2002-09-10 Baxter International Inc. Pre-slit injection site and tapered cannula
EP0354947B1 (en) * 1988-01-25 1994-07-20 BAXTER INTERNATIONAL INC. (a Delaware corporation) Pre-slit injection site and tapered cannula
US6261266B1 (en) 1988-01-25 2001-07-17 Baxter International Inc. Pre-slit injection site and tapered cannula
US6217568B1 (en) 1988-01-25 2001-04-17 Edwards Lifesciences Corporation Preslit injection site and tapered cannula for blood sampling
US6213996B1 (en) 1988-01-25 2001-04-10 Baxter International Inc. Pre-slit injection site and tapered cannula
US5871500A (en) * 1988-01-25 1999-02-16 Baxter International Inc. Pre-slit injection site and tapered cannula
US6569125B2 (en) 1988-01-25 2003-05-27 Baxter International Inc Pre-slit injection site and tapered cannula
US5080654A (en) * 1989-09-18 1992-01-14 Applied Medical Technology, Inc. Fluid injection device for intravenous delivery system
US5443791A (en) * 1990-04-06 1995-08-22 Perkin Elmer - Applied Biosystems Division Automated molecular biology laboratory
US5215537A (en) * 1990-09-13 1993-06-01 Lynn Lawrence A Septum for a blunt cannula
US20060013729A1 (en) * 1991-02-14 2006-01-19 Glen Carey Fluid handling apparatus for an automated analyzer
US20050266570A1 (en) * 1991-03-04 2005-12-01 Bayer Corporation Cuvette for an automated analyzer
US20020085959A1 (en) * 1991-03-04 2002-07-04 Glen Carey Cuvette for an automated analyzer
US7182912B2 (en) 1991-03-04 2007-02-27 Bayer Corporation Fluid handling apparatus for an automated analyzer
US20030194349A1 (en) * 1991-03-04 2003-10-16 Glen Carey Fluid handling apparatus for an automated analyzer
US5776125A (en) * 1991-07-30 1998-07-07 Baxter International Inc. Needleless vial access device
US6663599B2 (en) 1992-05-06 2003-12-16 Cook Incorporated Hemostasis cannula
US20040153021A1 (en) * 1992-05-06 2004-08-05 Osborne Thomas A. Hemostasis cannula
US20050192537A1 (en) * 1992-05-06 2005-09-01 Osborne Thomas A. Hemostasis cannula
US7445611B2 (en) 1992-05-06 2008-11-04 Cook Incorporated Hemostasis cannula
US8753317B2 (en) 1992-05-06 2014-06-17 Cook Medical Technologies Llc Hemostasis cannula
US5300034A (en) * 1992-07-29 1994-04-05 Minnesota Mining And Manufacturing Company Iv injection site for the reception of a blunt cannula
US5400500A (en) * 1992-07-29 1995-03-28 Minnesota Mining And Manufacturing Company Apparatus for making an injection or sampling site
US5351383A (en) * 1992-07-29 1994-10-04 Minnesota Mining And Manufacturing Company Method of making an injection or sampling site
US5376077A (en) * 1992-12-04 1994-12-27 Interventional Technologies, Inc. Introducer sheath with seal protector
US5322516A (en) * 1993-05-20 1994-06-21 Cobe Laboratories, Inc. Safety needle system and method for using the same
US5328041A (en) * 1993-06-30 1994-07-12 Abbott Laboratories Two piece stopper for blunt fluid connector
US5354275A (en) * 1993-09-13 1994-10-11 Minnesota Mining And Manufacturing Company Injection or sampling site
US5622183A (en) * 1993-11-09 1997-04-22 Hazard; James T. Urine specimen and other body fluids collection device
US5549577A (en) * 1993-12-29 1996-08-27 Ivac Corporation Needleless connector
US7635357B2 (en) 1994-06-20 2009-12-22 Mayer Bruno Franz P Needleless injection site
US5983770A (en) * 1994-08-03 1999-11-16 Abbott Laboratories Reseal with a partial perforation and method and apparatus for creating a partial perforation in a reseal
EP0773776B1 (en) * 1994-08-03 2000-04-19 Abbott Laboratories A reseal with a partial perforation and method and apparatus for creating a partial perforation in a reseal
US5928935A (en) * 1995-09-26 1999-07-27 Reuss, Jr.; William Alexander Biological specimen containment and incubation device
US6562298B1 (en) 1996-09-19 2003-05-13 Abbott Laboratories Structure for determination of item of interest in a sample
US5856194A (en) * 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
US5795784A (en) * 1996-09-19 1998-08-18 Abbott Laboratories Method of performing a process for determining an item of interest in a sample
US6050935A (en) * 1997-05-09 2000-04-18 Biofertec Container assembly for intravaginal fertilization and culture and embryo transfer and method of intravaginal fertilization and culture employing such a container
US5957898A (en) * 1997-05-20 1999-09-28 Baxter International Inc. Needleless connector
US6669681B2 (en) 1997-05-20 2003-12-30 Baxter International Inc. Needleless connector
US6261282B1 (en) 1997-05-20 2001-07-17 Baxter International Inc. Needleless connector
US6416499B2 (en) 1997-07-30 2002-07-09 Cook Incorporated Medical fluid flow control valve
WO2002036182A3 (en) * 2000-11-03 2002-11-07 Chromatography Res Supplies In Septum with chamfer and linear pre-piercing
WO2002036182A2 (en) * 2000-11-03 2002-05-10 Chromatography Research Supplies, Inc. Septum with chamfer and linear pre-piercing
US6936031B2 (en) 2000-12-12 2005-08-30 Gambro Dasco S.P.A. Site for access to the inside of a channel, and corresponding cannula
US20020091359A1 (en) * 2000-12-12 2002-07-11 Luca Caleffi Site for access to the inside of a channel, and corresponding cannula
US20040199126A1 (en) * 2001-12-07 2004-10-07 Harding Weston F Needleless luer access connector
US7713250B2 (en) 2001-12-07 2010-05-11 Becton, Dickinson And Company Needleless luer access connector
US20100179489A1 (en) * 2001-12-07 2010-07-15 Becton, Dickinson And Company Needleless luer access connector
US7947032B2 (en) 2001-12-07 2011-05-24 Becton, Dickinson And Company Needleless luer access connector
US20040217081A1 (en) * 2003-04-17 2004-11-04 Grainer Bio-One Gmbh Container system and closure device comprising a sealing device and cap
US20060142705A1 (en) * 2003-04-24 2006-06-29 Halili Edgardo C Implantable medication delivery device having needle receiving slot
US20080289975A1 (en) * 2007-05-23 2008-11-27 Imperial Toy, Llc Spill Resistant Container and Toy
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US20130174937A1 (en) * 2011-07-26 2013-07-11 Hainan Weikang Pharmaceutical (Qianshan) Co.,Ltd Puncture Free Bottle Cork and the Application Thereof
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